• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.11
• /
• pp.4617-4622
• /
• 2014

Background: Several studies have previously focused on associations between the (GT)n repeat polymorphism of the heme oxygenase-1 (HO-1) gene promoter region and risk of cancers, but results are complex. We conducted the present meta-analysis to integrate relevant findings and evaluate the association between HO-1(GT)n repeat polymorphism and cancer susceptibility. Materials and Methods: Published literature was retrieved from the PubMed/MEDLINE, EMBASE and ISI Web of Science databases before November 2013. For all alleles and genogypes, odds ratios were pooled to assess the strength of the associations using either fixed-effects or random-effects models according to heterogeneity. Subgroup analysis was conducted according to ethnicity and histopathology. Results: A total of 10 studies involving 2,367 cases and 2,870 controls were identified. The results showed there was no association between HO-1 (GT)n repeat polymorphism and the cancer risk both at the allelic and genotypic level. However, in the stratified analysis, we observed an increased risk of squamous cell carcinoma in persons carrying the LL genotype and the LL+LS genotype as compared with those carrying the SS genotype. When the LS and SS genotypes were combined, the odds ratio for squamous cell carcinoma in LL-genotype carriers, were also significantly increased. No publication bias was observed. Conclusions: The LL genotype and L-allele carrying genotypes (LL+LS) of HO-1 (GT)n repeat polymorphism are potential genetic factors for developing squamous cell carcinoma. More large and well-designed studies are required for further validations.

• Journal of Korean Public Health Nursing
• /
• v.12 no.1
• /
• pp.55-74
• /
• 1998

In the past most major accidents resulted in death, but today there is a dramatic increase in the number of people who survive such accidents but who are left with permanent injury. Particularly, children who are inquisitive about their surroundings but immature in their ability to assess danger, are more vulnerable to accidents and their causes as well as to determine attitudes towards prevention. The main objective of the study was to assess the effectiveness of using an accident prevention manual for accident for accident prevention education. The study was a quasi-experimental study using a questionnaire format. The subjects of the study were 393 mothers of children attending six day care centers in Seoul. Data collection was done between May 1 and June 15, 1997. The tools used for the study were a questionnaire developed the researchers and a manual for accident prevention. The collected data were analyzed using SPSS. The results of the study are as follows: 1. Types of accidents included stabbing, bums, falls from heights, choking, falls on slippery surfaces, traffic accidents, drowning, poisoning, and electrical shock in that order of frequency. 2. The main causes of accidents in children were from cosmetics and household medications. 3. The most frequent locations of accidents in the home were the bathroom, kitchen, and stairways in that order. 4. For $90.4\%$ of children safety seats were not used when the ridding in a car. 5. In examining the parents' accident prevention practices, it was found that many parents used only . one electrical outlet for many appliances, tending to overload the electricity lines and that they were not practically concerned bout the flammability of children's pajamas, indicating a less than positive attitude towards fire prevention. 6. The parents had not provided their children with any instruction on accident prevention or on what to do after an accident had occurred. 7. After the use of pamphlet in an accident prevention education program, it was found that there was a statistically significant difference in the degree to which children carried out safety measures (t=14.96, p=.000) and in their safety habits (t=-1.67, p<.1) indicating an effectiveness in this method of education. The results of this study showed that there are many things in a child's environment that can cause accidents and that the possibility of an accident occurring is high. So nurses looking after children should be aware of the need for safety education to prevent accidents in the home and plan to provide appropriate educational material to help parents with this education.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.8
• /
• pp.495-500
• /
• 2020

As the prevention of dementia is more important than the treatment after the onset, attention has focused on the prevention of dementia in the elderly. For this study based on 11 integrated programs, we analyzed the domestic research trends of dementia prevention programs for the elderly from 2000 to 2018 in the study of Yang Su-gyeong, Ko Bo-sook, and Park Jeong-hwan (2019) We reviewed the literature research on the elderly's dementia prevention program centered on play. By activity type, music, language, and physical activity were 4 (40.0%), respectively, and games, art, and work were 3 (30.0%), respectively. Dance, literature, traditional play, and recreation were 2 (20.0%), and yoga and life were 1 (10.0%), respectively. In this study, for the purpose of exploring the possibility of using the contents of early childhood education in the elderly dementia prevention program, play shows very positive aspects such as physical exercise ability, positive emotions, and emotional characteristics for the elderly. It is considered that if dementia prevention programs are developed using the contents of early childhood education for the elderly, they will be able to utilize leisure time positively while providing continuous services and maintaining group experiences and mental health.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.10
• /
• pp.6103-6108
• /
• 2013

Objective: Excision repair cross-complementing group 6 (ERCC6) is a major component of the nucleotide excision repair pathway that plays an important role in maintaining genomic stability and integrity. Several recent studies suggested a link of ERCC6 polymorphisms with susceptibility to various cancers. However, the relation of ERCC6 polymorphism with gastric cancer (GC) risk remains elusive. In this sex- and age-matched case-control study including 402 GC cases and 804 cancer-free controls, we aimed to investigate the association between a potentially functional polymorphism (rs1917799 T>G) in the ERCC6 regulatory region and GC risk. Methods: The genotypes of rs1917799 were determined by Sequenom MassARRAY platform and the status of Helicobacter pylori infection was detected by enzyme-linked immunosorbent assay. Odd ratios (ORs) and 95% confidential interval (CI) were calculated by logistic regression analysis. Results: Compared with the common TT genotype, the ERCC6 rs1917799 GG genotype was associated with increased GC risk (adjusted OR=1.46, 95%CI: 1.03-2.08, P=0.035). When compared with (GT+TT) genotypes, the GG genotype also demonstrated a statistical association with increased GC risk (adjusted OR=1.38, 95%CI: 1.01-1.89, P=0.044). This was also observed for the male subpopulation (GG vs. TT: adjusted OR=1.71, 95%CI: 1.12-2.62, P=0.013; G allele vs. T allele: adjusted OR=1.32, 95%CI: 1.07-1.62, P=0.009). Genetic effects on increased GC risk tended to be enhanced by H. pylori infection, smoking and drinking, but their interaction effects on GC risk did not reach statistical significance. Conclusions: ERCC6 rs1917799 GG genotype might be associated with increased GC risk in Chinese, especially in males.

• Child Health Nursing Research
• /
• v.9 no.2
• /
• pp.180-189
• /
• 2003

Purpose: To provide basic data for developing problematic drinking prevention problem through the investigation of the educational needs on drinking of primary students. Method: Subjects were 630 fourth, fifth, and sixth grades in 5 primary schools in Seoul. Data were collected from November to December 2000 by using structured questionnaire. Result: 1) Among the students under inquiry, 41.2％ answered the had educational need about drinking. Educational need about drinking was significantly higher in the students with higher mothers educational level than those of with lower ones. 2) With regard to the appropriate class in providing education, 37.3％ selected normal class education. 47.3％ of the respondents said experiments would be the most effective education method. 61.8％ of the students picked school nurses as the most appropriate person in carrying out the education. As for the most effective media for education, 40.3％ chose video/television. The most concerning topic was academic achievement with 51.9％ of the surveyed. As for the rate of preference in methods of drinking prevention education, Significant differences were shown in the class, teaching method, instructor, media, memory of education and concerning topic according to the gender. Conclusion: The results of the finding suggest that the various programs of drinking prevention education for the primary students should be developed with consider the difference of preference by the grade and the gender.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.6
• /
• pp.2947-2951
• /
• 2016

A quasi-experimental study was conducted to develop a health education modification program based on self-efficacy and motivation regarding liver flukes and cholangiocarcinoma development in Keang Sanam Nang district, Nakhon Ratchasima province, Thailand. A total of 36 individuals were invited to participate in the program and were screened for population at risk of liver fluke infection and cholangiocarcinoma using SUT-OV-001 and SUT-CCA-001. Development of health education modification program regarding liver fluke and cholangiocarcinoma prevention included 3 steps: (1) preparation, (2) health education program, and (3) follow-up and evaluation. The study was implemented for 10 weeks. Pre-and-post-test knowledge was measured with questionnaires, Kuder-Richardson-20: KR-20 = 0.718,and Cronbach's Alpha Coefficient = 0.724 and 0.716 for percection and outcome expectation questionnaires. Paired and independent t-tests were applied for data analysis. The majority of the participants were female (55.6%), aged between ${\leq}50$ and 60 years old (36.1%), married (86.1%), education level of primary school (63.9%), agricultural occupation (80.6%), and income <4,000 Baht (44.4%). The results revealed that after the health education program, the experimental group had a mean score of knowledge, perception, and outcome expectation regarding liver fluke and cholangiocarcinoma prevention significantly higher than before participation and in the control group. In conclusion, this successful health education modification program for liver fluke and cholangiocarcinoma, therefore may useful for further work behavior modification in other epidemic areas.

• The Journal of Korean Society for School & Community Health Education
• /
• v.9 no.1
• /
• pp.99-113
• /
• 2008

Background: School is a primary health education setting for students and the related continuous support should be provided to renovate school health education curriculum consistent to socio-cultural changes in Korean society. Objectives: This study was conducted to identify the principals' and teachers' needs and perceptions of health education topics for high school students and to analyze their conceptual map for health education curriculum in Korean high school. Methods: The sample size of the preliminary survey was 77 and that of the main survey was 276 who successfully participated in the survey among the high school teachers selected from the stratified sampling over Korea. The self-administered mailing survey was conducted to identify the factor structure of the health education topics and to analyze the conceptual properties with exploratory factor analysis and multidimensional scaling analysis in SPSS 12.0. Results: A total of 31 health education topics were generated from the preliminary survey. The five factors were determined: 'health promotion behavior and management', 'injury and sexual harassment prevention', 'bulling and aggression prevention', 'public regularity and safety perception' and 'smoking and drinking prevention'. The mean score of health education needs was between medium to high and 'public regularity and safety perception' had the highest score of education need. The two-dimensional cooperates were generated for the 31 health education topics and the two dimensional properties which divided the conceptual space were 'disease-injury' for one and 'public/environmental/individual/personal' for the other. Conclusions: Health education curriculum and its textbook should be developed considering teachers' needs and field environments for health education in every school. Therefore developing field-based health education curriculum and the textbooks should be the essential key to realize problem-solving health education for youth in real school fields.

• Journal of Korean Academy of Nursing
• /
• v.44 no.5
• /
• pp.525-533
• /
• 2014

Purpose: This study was done to propose and test a predictive model that would explain and predict fall prevention behaviors in postmenopausal women. The health belief model was the theoretical basis to aid development of a nursing intervention fall prevention program. Methods: Data for 421 postmenopausal women were selected from an original data set using a survey design. The structural equation model was tested for 3 constructs: modifying factors, expectation factors, and threat factors. Expectation factors were measured as relative perceived benefit (perceived benefit minus perceived barrier), self-efficacy, and health motivation; threat factors, as perceived susceptibility (fear of falling) and perceived severity (avoiding activity for fear of falling); and modifying factors: level of education and knowledge about fall prevention. Data were analyzed using SPSS Windows and AMOS program. Results: Mean age was 55.7 years (range 45-64), and 19.7% had experienced a fall within the past year. Fall prevention behaviors were explained by expectation and threat factors indicating significant direct effects. Mediating effect of health beliefs was significant in the relationship between modifying factors and fall prevention behaviors. The proposed model explained 33% of the variance. Conclusion: Results indicate that fall prevention education should include knowledge, expectation, and threat factors based on health belief model.

• Journal of Korean Academy of Nursing Administration
• /
• v.19 no.3
• /
• pp.394-403
• /
• 2013

Purpose: The purpose of this study was to identify self-leadership and attitude to patient falls and fall prevention behavior in nurses. Methods: The participants were 178 nurses from two general hospitals in Seoul. Data were collected from March 20 to May 10, 2012 using structured questionnaires which included a Self-leadership scale, Fall attitude scale, and Fall prevention scale. Data were analyzed using descriptive statistics, Pearson correlation and Hierarchial multiple regression with the SPSS/WIN 20.0 program. Results: The mean score for nurses' self-leadership was 3.48 (5 point scale). The average reported fall attitude was 3.59 (5 point scale) and fall prevention behavior was 3.26 (4 point scale). Self-leadership had a 18% explanatory power in fall attitude and a 5% explanatory power in fall prevention behavior. The factors which influenced fall prevention behavior were nurses' fall attitude (${\beta}$=.21, p=.009), fall prevention education (${\beta}$=.20, p=.007) and self-leadership (${\beta}$=.16, p=.047). All of the factors together had a 13.1% explanatory power. Conclusion: The results of this study suggest that provision of regularly fall prevention education to nurses is required and should include a program to activate their positive attitude and self-leadership in order to improve fall prevention behavior in nurses.

• The Korean Journal of Rehabilitation Nursing
• /
• v.16 no.1
• /
• pp.55-62
• /
• 2013

Purpose: The purpose of this study was to identify the factors affected with nurses' prevention activity against hospital fall. Methods: The data were collected from 325 nurses at C University Hospital in G City by using the structured questionnaires from February 21, 2011 to March 12, 2011. The data were analyzed by stepwise multiple regression. Results: The main factor associated with prevention activity against hospital fall was the attitude towards hospital fall (${\beta}$=.26, p<.001), the next one was the educational level (${\beta}$=.16, p=.002), and the last one was the frequency of fall prevention education (${\beta}$=.14, p=.009). The all factors could explain 11.1% of the variance in the nurses' prevention activities against hospital fall. Conclusion: Hospital managers need to make hospital culture to enhance the nurse's positive attitude about hospital fall prevention. In addition, educators need to develop educational programs including hospital fall prevention through academic curriculum and continuing education.