• Title/Summary/Keyword: Prevention Control

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Exploration of Functional Materials from Oriental Medicine Extracts Cultured with Tricholoma Matsutake Mycelium - (2) Effect of Extracts on Blood Glucose and Liver Function in Streptozotocin-Induced Diabetic Rat -

  • Kim, Hae-Ja;Choi, Yun-Hee;Cho, Hwa-Eun;Hong, Hak-Gi;Han, Jung-Ho;Lee, Ki-Nam
    • Journal of Society of Preventive Korean Medicine
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    • v.12 no.2
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    • pp.13-25
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    • 2008
  • The purpose of this study was to investigate extract from mixed culture with Trichloloma matsutake mycelium in oriental medicine and cereal medium(OCM) to develop new material for pharmaceutical products and medicinal food for diabetes mellitus. To evaluate of hypoglycemic activity of OCM extracts, we examined the inhibitory activity of ${\alpha}$-glucosidasein OCM, blood glucose level and liver function of streptozotocin(STZ) induced diabetic rat. Experimental group was divided into 6 groups: first, it was divided into normal control group(hereafter NC group) and diabetes-induced group, and diabetes-induced group was subdivided into diabetic control group(DC group), treated by hot water extracts group(HE), ultra sonic waves, micro waves, and micro bubble extracts g roup(UE), crude polysaccharide of HE group (HEE) and crude polysaccharide of UE group(UEE) at a dose of 300mg/kg/body weight, respectively. In diabetic-induced groups, after streptozotocin was melted in 0.01M citrate buffer at 50mg/kg/body weight, when the non-fasting blood glucose levelwas 300 mg/dl or more in blood collected from the tail vein, it was regarded as diabetic induction and then such diabetic-induced experimental animals were used in this experiment. At the end of the experiment, blood glucose level increased by 4.19% in DC group but significantly decreased by 32.34%, 19.19%, 17.81% and 17.64%, respectively in UEEE, UE, HE, and HEE groups. In the cases of AST, ALT, and ALP, the experiment group treated with extracts showed significantly lowerblood glucose level than DC group. The levels of BUN and uric acid were found to be lower in the UMPM extract group(UE) than HW extract group(HE), which implies that herb medicine medium extracts in which Tricholoma matsutake mycelia were cultured are effective in reducing impaired liver function as well as high blood glucose level caused by diabetes. In addition, the administration of low temperature UMPM extracts was found to produce better results than that of high temperature hot water extracts. In this regard, it is expected that extracts from herb medicine obtained by cultivating Tricholoma matsutake mycelia will be widely used as new ingredients for foods and medicines for prevention and treatment of diabetes.

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Development of an Underwater Rope-cutter Device and Controller for Removal of Propeller and Shaft Foreign Material for Small Vessel (소형선박용 프로펠러 및 샤프트 이물질 제거를 위한 수중절단기 기구 설계 및 제어기 개발)

  • Lee, Hunseok;Oh, Jin-Seok;Choi, Sun-Hong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.7
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    • pp.927-935
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    • 2019
  • Screw-failure accidents in small ships frequently occur in coastal waters. In particular, vessels' propulsion systems are frequently coiled due to objects such as fish-nets and ropes that float on the sea. The failure of the ship's propulsion system can cause primary accidents such as ship operation delays and drifting due to loss of power; furthermore, the possibility of secondary accidents such as those involving operators in the underwater removal of rope stuck in a propeller. Ships that do not have the proper tools to solve these problems must be either lifted onto land to be repaired or divers must dive directly under the ship to solve the problem. Accordingly, some small vessels have been equipped with rope-cutter devices on the propeller shaft to prevent ship propeller system accidents in recent years; however, they are not being applied efficiently due to the cost and time of installation. To solve these problems, this study develops an underwater rope-cutter device and controller for the removal of propeller and shaft foreign material in small vessels. This device has simple structures that use the principle of a saw. Meteor gears and crank pins were used for the straight-line rotation of saw blades of the underwater rope-cutters to allow for long strokes. Furthermore, the underwater rope-cutting machines can be operated by being connected to the ship battery. The user, a non-professional, can ensure convenience and stability by applying reverse current prevention and a speed control circuit so that it can be used more conveniently and safely.

Effects of herbal acupuncture(Atratylodes japonica, Coix lachrymajobi, Ephedra sinica, Atratylodes japonica mixed with Coix lachrymajobi and Ephedra sinica mixed with Green tea) at Pungnyung(ST40) and Umnungchon(SP9) in obese Rats induced by high fat diet (고지방식이(高脂肪食餌)로 유발(誘發)된 비만백서(肥滿白鼠)모델에서 창출(蒼朮), 의이인(薏苡仁), 마황(麻黃), 창출합의이인(蒼朮合薏苡仁) 마황합록차(麻黃合綠茶) 약침(藥鍼)이 혈청지질(血淸脂質) 및 간기능(肝機能)에 미치는 영향(影響))

  • Youn, Dae-Hwan;Kang, Ja-Don;Joo, Joon-Sung;Chae, Woo-Seok;Na, Chang-Su
    • Journal of Pharmacopuncture
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    • v.7 no.1 s.12
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    • pp.87-100
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    • 2004
  • Objective : This research was performed to investigate the effect of herbal acupuncture(Atratylodes japonica, Coix lachrymajobi, Ephedra sinica, Atratylodes japonica mixed with Coix lachrymajobi and Ephedra sinica mixed with Green tea) at Pungnyung(ST40) and Umnungchon(SP9) on weight gain, food intake, food efficiency, serum of lipid concentrations, liver function and HDL to total cholesterol ratio of rats fed high fat diet for 5weeks. Method : Experimental groups were divided into normal group(Normal), high fat diet group(Control), high fat diet and Atractylodes japonica-herbal acupuncture group(AJ), high fat diet and Coix lachrymajobi-herbal acupuncture group(CL), high fat diet and Ephedra sinica-herbaI acupuncture group(ES), high fat diet and Atractylodes japonica+Coix lachrymajobi-herbal acupuncture group(AJ+CL), Ephedra sinica+Green tea-herbal acupuncture group(ES+GT). Herbal acupuncture was bilaterally treated at the level of 132.5mg/kg body weight per 2day. Results : Body weight and food efficiency were decreased in AJ, ES, AJ+CL, ES+GT. The level of serum total cholesterol, triglyceride and free fatty acid were increased in AJ, ES, ES+GT. That of serum HDL-cholesterol was increased in AJ. The change of food intake, the level of serum phospholipid and ALP were not significant. The HDL to Total cholesterol ratio was increased in AJ and ES. Conclusion : Atractylodes japonica-herbal acupuncture in ST40 SP9 is effective on Body weight, food efficiency ratio, the level of serum lipid, protection of liver function and prevention cardiovascular risk by obesity induced by high fat diet. Herbal acupuncture mixed Ephedra sinica with Green tea can control the body weight, food efficiency ratio and the level of serum lipid.

Design and Implement a Smart Control System of Door Security Guard (도어 안전고리 스마트 제어시스템 설계 및 구현)

  • Lee, Hyo Seung;Oh, Jae Chul
    • Smart Media Journal
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    • v.6 no.1
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    • pp.61-67
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    • 2017
  • A large number of people living in modern times prefer remaining unmarried or living alone independently for the reason of their own will or another person's will. This is because they dislike being interfered with by other persons or because there is a financial problem. This behavior has become mainstream in persons working for professional jobs, persons having a strong disposition toward individual activity or college students. In particular, career women pursuing their own comfortable life have the tendency to prefer single life. However, sometimes, they become a target of crime that targets and makes bad use of this point. For these reasons. Consequently, sometimes, they additionally install and use a security system such as door security guard at front door and so on. It is not so difficult to lock the door security guard at the front door. However, it is apt to be forgotten. And when they are on the bedspread before falling asleep, in case they should check whether the door security guard is locked or in case they should lock it, they should get up, go to the entrance, and check and lock the door security guard. They often don't lock the door security guard due to their feeling that it is all right because of annoyance and inconvenience. This paper is intended to work for safety from crime such as illegal housebreaking by more conveniently using the door security guard after designing and implementing a system that can remotely control the door security guard, using a smartphone as a method of resolving this annoyance and keeping life more safe.

Analysis of Soil Erosion and Sediment Yields at the Doam-dam Watershed considering Soil Properties from the Soil Reconditioned Agricultural Fields using SATEEC System (SATEEC 시스템을 이용한 객토 토양의 토성고려에 따른 도암댐 유역의 토양유실 및 유사량 분석)

  • Yoo, Dongsun;Ahn, Jaehun;Yoon, Jongsuk;Heo, Sunggu;Park, Younshik;Kim, Jonggun;Lim, Kyoung Jae;Kim, Ki-sung
    • Journal of Korean Society on Water Environment
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    • v.23 no.4
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    • pp.518-526
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    • 2007
  • There have been serious soil erosion and water pollution problems caused by highland agriculture practices at Doam-dam watershed. Especially agricultural activities, chemical and organic fertilizer and pesticide applications, soil reconditioning to maintain soil fertility are known as primary causes of soil erosion and water qaulity degradation in the receiving water bodies. Among these, soil reconditioning can accelerate soil erosion rates. To develop soil erosion prevention practices, it is necessary to estimate the soil erosion from the watershed. Thus, the Universal Soil Loss Equation (USLE) model has been developed and utilized to assess soil erosion. However, the USLE model cannot be used at watershed scale because it does not consider sediment delivery ratio (SDR) for watershed application. For this reason, the Sediment Assessment Tool for Effective Erosion Control (SA TEEC) was developed to assess the sediment yield at any point in the watershed. The USLE-based SA TEEC system can estimate the SDR using area-based SDR and slope-based SDR module. In this study, the SATEEC system was used to estimate soil erosion and sediment yield at the Doam-dam watershed using the soil properties from reconditioned agricultural fields. Based on the soil sampling and analysis, the US LE K factor was calculated and used in the SA TEEC system to analyze the possible errors of previous USLE application studies using soil properties from the digital soil map, and compared with that using soil properties obtained in this study. The estimated soil erosion at the Doam-dam watershed without using soil properties obtained in the soil sampling and analysis is 1,791,400 ton/year (123 ton/ha/year), while the soil erosion amount is 2,429,900 ton/year (166.8 ton/ha/year) with the use of soil properties from the soil sampling and analysis. There is 35 % increase in estimated soil erosion and sediment yield with the use of soil properties from soil reconditioned agricultural fields. Since significant amount of soil erosion are known to be occurring from the agricultural fields, the soil erosion and sediment yield from only agricultural fields was assessed. The soil erosion rate is 45.9 ton/ha/year without considering soil properties from soil reconditioned agricultural fields, while 105.3 ton/ha/year after considering soil properties obtained in this study, increased in 129%. This study shows that it is very important to use correct soil properties to assess soil erosion and sediment yield simulation. It is recommended that further studies are needed to develop environment friendly soil reconditioning method should be developed and implemented to decrease the speed of soil erosion rates and water quality degradation.

Effects of (-)-Epigallocatechin-3-gallate on the Release of Pancreatic Enzymes and Expression of Regenerating Genes in Ethanol-injured Murine Pancreatic Primary Acinar Cells (에탄올에 의하여 유도된 마우스 췌장 선포세포의 염증성 손상에서 췌장분비 효소의 활성 및 세포 재생관련 유전자들의 발현에 미치는 EGCG의 영향)

  • Kim, Sung Ok;Choi, Yung Hyun
    • Journal of Life Science
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    • v.23 no.11
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    • pp.1404-1408
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    • 2013
  • (-)-Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, has been shown to have strong antibacterial, antiviral, antioxidant, anti-inflammatory, and chemopreventive effects. However it is unknown whether EGCG can recover alcohol-associated pancreatitis. The aim of this study was to investigate the effects of EGCG on pancreatic enzyme activities and the expressions of pancreatic regenerating related markers, such as adenosine monophosphate-activated protein kinase (AMPK), raf-1 kinase inhibitor protein (RKIP), and Regenerating gene 1 (Reg1), in mice pancreatic primary acinar cells. Our results revealed that activities of ${\alpha}$-amylase and chymotrypsin were significantly increased in the cells treated with ethanol compared to the untreated control cells; however, the increased activities of both enzymes were markedly reduced by pretreatment with EGCG. Phosphorylation of AMPK and total expression of RKIP were decreased in the ethanol-treated primary acinar cells; however, these were both significantly increased in the EGCG-pretreated cells. In addition, when EGCG was treated, expression of Reg1 was markedly increased compared with that of the control or the ethanol-treated primary acinar cells, demonstrating that EGCG can modulate pancreatic regenerating related genes. Therefore, our findings suggest that EGCG may have therapeutic utility in the prevention or treatment of alcohol-associated pancreatitis.

Control of Suspended Dust in Various Ventilation Systems of Cement Packaging Process (시멘트 포장공정에서 환기시스템에 따른 발생분진의 제어)

  • Lee, Seung-Chul;Kim, Soo-Chang;Noh, Kwang-Chul;Park, Myoung-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.3
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    • pp.463-469
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    • 2009
  • We performed the experimental study on the control of suspended dust in a cement packaging process for various ventilation systems. To effectively remove the dust generated in the cement packaging process, three different kinds of ventilation system, such as local exhaust ventilation, electrostatic scrubber, and local air supply system, were adopted. Dust concentrations in the packaging process were measured with the variation of the airflow rate of the ventilation systems and then their ventilation performance were evaluated. From the results, we knew that the ventilation performance was the best when the local exhaust ventilation and the electrostatic scrubber were simultaneously operated in the packaging process. In the electrostatic scrubber system, the effect of the airflow rate on the indoor dust removal efficiency was negligible so hat he system ust be operated at $2,700m^3/h$ for saving power consumption.

A Study on the Peak Runoff Reduction Effect of Seolleung·Jeongneung Zone by Applying LID(Low Impact Development) System based on the Landscape Architectural Technology (조경기술기반 LID 시스템 적용을 통한 선릉·정릉 권역의 첨두유출량 분석)

  • Kim, Tae-Han;Choi, Jong-Hee
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.35 no.4
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    • pp.126-133
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    • 2017
  • This study analyzed hydrological changes of stormwater runoff of Seolleung Jeongneung zone according to the application of LID system based on landscape Architectural technology. The results are as follows. First, when flooding occurred in Gwanghwamun in July 27, 2011, the maximum instantaneous rainfall amount was 183 mm/hr recorded at 10:00 on 27th for 10 minutes, and it was confirmed that rainfall intensity more than three times as high as the maximum rainfall of 57.5 mm/hr. Second, it is possible to control peak flow rate in the case of 1,500mm of soil thickness, so that it is possible to improve the vulnerability of flood damage in Seolleung and Jeongneung zone when applying the LID system. Third, in the berm height scenario, peak flow rate control was not controled in all depth level models, but the first stormwater runoff was delayed by 4 hours and 10 minutes compared to the soil thickness scenario. It was interpreted as a relatively important indicator the soil thickness for the initial stromwater runoff reduction and the berm height for the peak runoff. Through this, the systematic adaptation of landscape-friendly ecological factors within the cultural property protection zone could theoretically confirm the effects of flood disaster prevention.

Protective effects of Acanthopanax koreanum Kakai extract against carbon tetrachloride-induced liver injury in Sprague-Dawley rats (사염화탄소로 유도된 간 손상에 대한 섬오갈피 추출물의 보호 효과)

  • Yang, Yoon Kyoung;Wang, Lin;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.47 no.2
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    • pp.106-112
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    • 2014
  • Purpose: This study was conducted in order to investigate the protective effects of ethanolic extract of Acanthopanax koreanum Nakai (AE) against carbon tetrachloride ($CCl_4$)-induced liver injury in rats. Methods: Male Sprague-Dawley rats were randomly divided into four groups in order to receive the following experimental diets with intraperitoneal injection of $CCl_4$ (2.0 mL/kg body weight, 20% solution 0.65 mL) for eight weeks (n = 8 per group): $CCl_4$ control (CON), $CCl_4$ + AE 1% (AE1), $CCl_4$ + AE 3% (AE3), or $CCl_4$ + acanthoic acid 0.037%, which is equivalent to AE 3% (AA). Results: Highest serum ALT activity and albumin level were observed in the $CCL_4$ control group, but showed a significant decrease by either AE or AA supplementation in a dose-dependent manner (p = 0.0063 and 0.0076, respectively). Both hemotoxylin and eosin staining and Masson's staining indicated remarkable prevention of $CCl_4$-induced liver damage in the AE3 group. $TNF{\alpha}$ and IL-6 production were significantly lowered in the AE treated groups, but not in the AA group (p = 0.0016 and p = 0.0002, respectively). The effects of AE3 were greater than those of AA for inflammation and liver toxicity biomarkers. Conclusion: Taken together, the results suggested that ethanolic extract of Acanthopanax koreanum Nakai provided hepatoprotective effects, leading to the reduction of inflammatory response. In addition, the effect of AE was superior to that of single compound AA.

Investigation for Developing 3D Concrete Printing Apparatus for Underwater Application (수중적층용 3D 콘크리트 프린팅 장비 개발에 대한 연구)

  • Hwang, Jun Pil;Lee, Hojae;Kwon, Hong-Kyu
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.44 no.3
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    • pp.10-21
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    • 2021
  • Recently, the demand for atypical structures with functions and sculptural beauty is increasing in the construction industry. Existing mold-based structure production methods have many advantages, but building complex atypical structures represents limitations due to the cost and technical characteristics. Production methods using molding are suitable for mass production systems, but production cost, construction period, construction cost, and environmental pollution can occur in small quantity batch production. The recent trend in the construction industry calls for new construction methods of customized small quantity batch production methods that can produce various types of sophisticated structures. In addition to the economic effects of developing related technologies of 3D Concrete Printers (3DCP), it can enhance national image through the image of future technology, the international status of the construction civil engineering industry, self-reliance, and technology export. Until now, 3DCP technology has been carried out in producing and utilizing residential houses, structures, etc., on land or manufacturing on land and installing them underwater. The final purpose of this research project is to produce marine structures by directly printing various marine structures underwater with 3DCP equipment. Compared to current underwater structure construction techniques, constructing structures directly underwater using 3DCP equipment has the following advantages: 1) cost reduction effects: 2) reduction of construct time, 3) ease of manufacturing amorphous underwater structures, 4) disaster prevention effects. The core element technology of the 3DCP equipment is to extrude the transferred composite materials at a constant quantitative speed and control the printing flow of the materials smoothly while printing the output. In this study, the extruding module of the 3DCP equipment operates underwater while developing an extruding module that can control the printing flow of the material while extruding it at a constant quantitative speed and minimizing the external force that can occur during underwater printing. The research on the development of 3DCP equipment for printing concrete structures underwater and the preliminary experiment of printing concrete structures using high viscosity low-flow concrete composite materials is explained.