• The Korean Journal of Physiology and Pharmacology
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• 제6권1호
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• pp.57-61
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• 2002

The renoprotective activities of white ginseng radix and rootlet were compared in spontaneously hypertensive rat (SHR) with diabetes. During oral administration of white ginseng radix (Ginseng Radix Alba, GRA) and white ginseng rootlet (Ginseng Radix Palva, GRP) for four weeks, arterial blood pressure and blood glucose levels were determined at every 10 days. In both GRA- and GRP-treatment groups, arterial blood pressures started to go down after 10 days of administration and maintained throughout the study period. After four weeks administrations of GRA and GRP, diastolic blood pressures were significantly decreased with 17% and 9%, respectively. GRA treatment also decreased blood glucose levels after 10 days of administration when compared with diabetic SHR group. At the end of the experiment, serum creatinine (Scr) and blood urea nitrogen (BUN) were not significantly different between the groups, except 62% higher value of BUN in diabetic SHR group when compared with SHR group. In the diabetic SHR group, the excretion of urinary albumin was increased significantly when compared with SHR. The level of urinary albumin in GRA treated group was markedly reduced when compared with diabetic SHR group $(67.8{\pm}4.7\;vs.\;131.3{\pm}13.5\;mg/24\;h).$ To examine the effects of ginseng radices on an overt diabetic nephropathy, index of kidney hypertrophy and transforming growth $factor-{\beta}1\;(TGF-{\beta}1)$ protein levels were evaluated. The glomerular and tubular cells stained positive for $TGF-{\beta}1$ seemed to be more abundant in diabetic SHR than in those with SHR, and GRA treated rats showed somewhat less $TGF-{\beta}1$ protein in glomerular and tubular cells when compared with diabetic SHR. Our results suggest that GRA might be a useful antihypertensive and antidiabetic agent with renoprotective effect.

• 대한조선학회논문집
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• 제37권3호
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• pp.57-68
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• 2000

이착륙 속력을 줄이기 위해 날개 밑으로 프로펠러 후류를 불어넣어 날개와 수면사이의 압력을 증가시키는 PAR(Power Augmented Ram) 효과는 해면효과익선의 성능을 크게 향상시킨다. 본 논문에서는 풍동실험을 통해 이러한 PARWIG(Wing in Ground)선의 공력특성을 연구하였으며 송풍기(blower)와 덕트(duct)를 사용한 제트분사를 프로펠러 후류로 대신하였다. 제트의 분사속도, 분사위치(수평 및 수직 방향), 분사각 및 덕트 직경 변화에 대해 20인승 PARWIG선의 1/25 축소 모형선의 지면과의 고도, 앙각 및 플랩각의 변화에 따른 양력, 항력 및 피치모멘트를 계측하여 공력특성을 비교하였다. 적절한 PAR효과의 사용은 양력을 크게 증가시키며 최대 4의 양력계수까지 얻을 수 있었다.

• 한국전산유체공학회지
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• 제21권2호
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• pp.90-98
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• 2016

A numerical study is conducted on thermal performance of a large-area hot plate specially designed as a heating and cooling tool for thermal nanoimprint lithography process. The hot plate has a dimension of $240mm{\times}240mm{\times}20mm$, in which a series of cartridge heaters and cooling holes are installed. The material is stainless steel selected for enduring the high molding pressure. A numerical model based on the ANSYS Fluent is employed to predict the thermal behavior of the hot plate both in heating and cooling phases. The PID thermal control of the device is modeled by adding user defined functions. The results of numerical computation demonstrate that the use of cartridge heaters provides sufficient heat-up performance and the active liquid cooling in the cooling holes provides the required cool-down performance. However, a crucial technical issue is raised that the proposed design poses a large temperature non-uniformity in the steady heating phase and in the transient cooling phase. As a remedy, a new hot plate in which heat pipes are installed in the cooling holes is considered. The numerical results show that the installation of heat pipes could enhance the temperature uniformity both in the heating and cooling phases.

• 한국소음진동공학회논문집
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• 제24권2호
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• pp.108-116
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• 2014

With the increasing the importance of emotional quality of vehicle, the sound quality of systems with electric motor components has become increasingly important. Electric motors are used for windows, seats, sun roof, mirrors, steering columns, windshield wiper and climate control blowers, etc. In this paper, a study was conducted to identify sound quality factors that contribute to customer's satisfaction and preference of the window lift system. Jury test for subjective evaluation was carried out and sound quality index was developed. Averaged sound pressure level and sharpness were significant factors when glass moves down. Also, maximum loudness at stop section and averaged loudness were significant factor when glass moves up. Next, noise source identification was carried out using beam forming method during glass transferred section and impulsive noise at stop section. Several improvement methods were applied using the source identification result. And finally, the degree of sound quality improvement was judged using sound quality index.

• Archives of Plastic Surgery
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• 제37권3호
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• pp.313-316
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• 2010

Purpose: Tie-over dressing is widely used to secure skin grafting on face, body, or extremities. It can be a rather complicated task and is not easy to make compressive dressing again if performed in a conventional method. So, we hereby introduce an easy reproducible tie over dressing method. Methods: After completing the skin graft, Cut the silastic drainage longitudinally in half and spread to the grafted skin margin. Drainage is fixed by using the stapes or sutures. A fluffy gauze bolus dressing is placed over a furacin impregnated gauze and wrapped around. After suturing the distal margin of silastics with opposite side using the silk thread either 5 - 0 or 3 - 0, knot of suturing, which is pressed down against the dressing while the threads are tightened, is made into center of each sides. Results: It can make dressing again after observing the grafted skin, and it can also make pressure on the grafted area evenly until the grafted skin is taken. Conclusion: This dressing method makes the surgeons and patients comfortable. To surgeons, it provides more rapid and easier way to do dressing, and to patients, it eliminates pain caused by redressing.

• Tribology and Lubricants
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• 제33권3호
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• pp.98-105
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• 2017

A pin-on-disk test is performed to measure the wear volume of a ductile cast iron (DCI) roll when it wears down using a high carbon steel and two alloy steels at different sliding velocities between the roll and the material (steel). Normal pressure is set as constant and test temperatures are 400, 500 and $600^{\circ}C$. In addition, thermal softening behavior of the DCI roll is examined using a high-temperature micro-hardness tester and the surface hardness variation of the DCI roll is expressed in terms of temperature and heating time. Based on experimental data, a wear coefficient used in Archard's wear model for each material is obtained. The wear volume is clearly observed when the test temperature is $400^{\circ}C$ and sliding velocity varies. However, it is not measured at temperatures of $500^{\circ}C$ and $600^{\circ}C$ even with variations in sliding velocity. From the optical photographs of the pin and disk, the abrasive wear is observed at $400^{\circ}C$ clearly, but no at $500^{\circ}C$ and $600^{\circ}C$. At higher temperatures, the pin surface is not smooth and has many tiny caves distributed on it. It is found that wear volume is dependent on the carbon contents rather than alloy contents. Results also reveal that the variations of wear coefficients are almost linearly proportional to the carbon contents of the material.

• Journal of Korean Biological Nursing Science
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• 제16권3호
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• pp.182-191
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• 2014

Purpose: The aim of this study was to identify necessary emergency treatment and nursing activities for severe trauma patients according to elapsed time and vital signs. Methods: A survey was conducted with 121 patients over 15 points ISS on EMR from June 1, 2011 to May 31, 2012. Collected data were analyzed with descriptive statistics, applying McNemar's test using SPSS 12.0. Results: Almost all of the subjects were men and the mean age was 46.9. Run-time for primary diagnosis, treatment decision, and leaving for the hospital room was 0.19, 4.36, and 4.21 hours, respectively, and stayover time was 9 hours. Regardless of vital signs, emergency treatments involving ambu-bagging, intubation, ventilator, and central vein catheterization insertion were offered within an hour. Central venous pressure, Foley catheter/Levin tube preparation and maintenance were performed in cases of unstable vital sign patients within an hour. Unrelated to vital signs, nursing activities for consciousness assessment, skin assesment and wound care, bed sore/fall down assesment and care, intravenous injection insertion and maintenance were conducted for all severe trauma patients within an hour. Foley catheter/Levin tube drainage care was performed for patients who had unstable vital signs within an hour. Conclusion: Emergency treatment and nursing activities for severe trauma patients were specific according to elapsed time and vital signs.

• 한국산학기술학회논문지
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• 제10권12호
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• pp.3546-3552
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• 2009

본 연구에서는 천정 설치형 공조기 적용을 위해 연구가 활발히 진행되고 있는 알루미늄 평행류 증발기 해석 프로그램을 개발하여 190mm*650mm*25mm(W*H*D) 크기의 열교환기를 해석하였다. R410A냉매의 분배비가 일정하고 상하로 유동하는 2, 3 패스의 경우와 3 패스이고 분배비율(1:1:1, 1:2:2)을 달리할 때, 열교환 성능을 예측하였다. 계산 결과, 2 패스가 3 패스보다 국소 전열량이 30% 정도 높았지만, 건도에 따른 열전달계수는 25% 낮았으며, 3 패스의 경우, 분배비 1:1:1 보다 1:2:2가 냉매 압력손실이 높게 나타났다. 본 해석에서는 패스당 냉매가 균일하게 분포하는 것으로 가정하였으므로, 패스별로 불균일하게 유동되는 실제의 경우보다 열교환성능을 과대 예측하는 것으로 판단된다.

• 한국자동차공학회논문집
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• 제12권3호
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• pp.101-108
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• 2004

A FEM-based efficient method is developed for the shape optimization of 2-D structures. The combined SLP and Simplex method are coupled with finite element analysis. Selected set of master nodes on the design boundaries are employed as design variables and assigned to move towards their normal directions. The other nodes along the design boundaries are grouped into the master node. By interpolating the repositioned master nodes, the B-spline curves are formed so that the rest mid-nodes efficiently settle down on the B-spline curves. Mesh smoothing scheme is also applied for the nodes on the design boundary to maintain most finite elements in good quality. Finally, a numerical implementation of optimum design of an automobile torque converter piston subjected to pressure and centrifugal loads is presented. The results shows additional weight up to 13% may be saved after the shape optimization.

• 대한의용생체공학회:의공학회지
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• 제32권1호
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• pp.55-60
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• 2011

Although sound intensity is considered as one of important factors in auditory processing, its neural mechanism in auditory neurons with limited dynamic range of firing rates is still unclear. In this study, we examined the effect of sound intensity adaptation on the change of glucose metabolism in a rat brain using [F-18] micro positron emission tomography (PET) neuroimaging technique. In the experiment, broadband white noise sound was given for 30 minutes after the [F-18]FDG injection in order to explore the functional adaptation of rat brain into the sound intensity levels. Nine rats were scanned with four different sound intensity levels: 40 dB, 60 dB, 80 dB, 100 dB sound pressure level (SPL) for four weeks. When glucose uptake during the adaptation of a high intensity sound level (100 dB SPL) was compared with that during adaptation to a low intensity level (40 dB SPL) in the experiment, the former induced a greater uptake at bilateral cochlear nucleus, superior olivary complexes and inferior colliculi in the auditory pathway. Expectedly, the metabolic activity in those areas linearly increased as the sound intensity level increased. In contrast, significant decrease interestingly occurred in the bilateral auditory cortices: The activities of auditory cortex proportionally decreased with higher sound intensities. It may reflect that the auditory cortex actively down-regulates neural activities when the sound gets louder.