• Archives of Pharmacal Research
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• v.27 no.6
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• pp.646-652
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• 2004

The objective of this study was to determine the acute effect of trimetazidine (TMZ) on the pre-fatigue, fatigue and post-fatigue contractile characteristics and tension-frequency relationships of isolated rat diaphragm muscle. Muscle strips were taken from the ventral-costal aspects of the diaphragm muscle of rats killed by decapitation. The muscle strips were suspended in organ baths containing Krebs solution, with a gas mixture of 95% $O_2$ and 5% $CO_2$ at $37^{\circ}C$ and pH 7.35-7.45. After determining the thermoregulation and optimum muscle length the muscles were subjected to direct supramaximal stimulation with 0.05 Hz frequency square pulses for periods of 0.5 msec to obtain control values. After adding $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine solution to the respective bath media, the contractile parameters of the muscles were recorded. The contractile parameters were also recorded for both the trimetazidine and tri-metazidine-free media after application of the high frequency fatigue protocols. Later, the tension-frequency relationship was determined by applying stimulating pulses of 10, 20, 50 and 100 Hz to the muscle strips. Whilst the twitch tension obtained from the $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine media showed numerical increases compared to that of the controls, these were not statistically significant (p>0.05). The contraction time exhibited a dose dependent increase (p<0.001), whilst the contraction and relaxation rates did not differ significantly. The isometric contraction forces obtained with the different stimulating frequencies showed a significant increase in the tetanic contraction only at 100 Hz (p<0.05). A comparison of the pre- and post-fatigue twitch tensions in the trimetazidine media showed the post- fatigue twitch tensions to be significantly higher than those of the pre-fatigue contraction forces (p<0.05). In the $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine media the increases in the post-fatigue contraction force were 22 and 30%, respectively. These results demonstrated that in isolated rat diaphragm muscle, TMZ significantly limited the mechanical performance decrease during fatigue. It is our opinion that trimetazidine contributed to the observed fatigue tolerance by eliminating the factors of fatigue, due to preservation of intracellular calcium homeostasis, provision of the ATP energy levels needed by ATPase dependent pumps and especially by keeping the intracellular pH within cer-tain limits.

• Journal of Agricultural Extension & Community Development
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• v.11 no.2
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• pp.279-290
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• 2004

This study aims to explore the benefits and extension's role with farmers' markets in USA. This study was conducted by literature review and case study. They help establish connections between consumers and food producers, provide an additional income source for farmers. and in general, serve as a tool for community development. First, from education to advocacy, from research to advising, extension educators have multiple roles to play in promoting the growth of farmers' markets. Second, it is essential that extension engage others who are interested in seeing the markets succeed and create opportunities for such groups to make the market unique in their given communities. Third, extension promotes farmers' markets through the creation and dissemination of how-to publications. These publications typically include tips about having a market establishing a prominent and easily accessible market location, and offering a sufficient product variety to ensure consumer satisfaction. Fourth, efforts by extension offices are already paying off for consumers, vendors, and communities. Involving those who will purchase as well as produce the foods sold at who will purchase as well as produce the foods sold at farmers' markets should diversify the audience extension educators reach. Fifth, extension educators can aid in this effort by encouraging farmers' market vendors to diversify their of offerings and to produce and sell value-added products. Sixth, many extension offices offer guides to the direct marketing venues in their counties, such as farmers' markets, pick your own operations, roadside stands, and community supported apiculture farms. Once such a guide is produced. extension educators can distribute it at workshops and inform local media about the guide so that they can publicize it. Seventh, extension educators should seek to involve those groups who can collaborators could include community economic development organizations, consumer groups, churches, food banks, land preservation organizations, school, farmers' organizations, and other community groups. Eighth, extension educators can also contribute to the improvement of existing markets by offering workshops for vendors in business management, advertizing, marketing, bookkeeping, personnel management, and food preservation. Ninth, farmer's market also provide an opportunity for extension to have face-to face communication with farmers. Tenth, if farmers' markets are well managed, these markets can provide economic, nutritive, educational, social and psychological benefits to venders and the community.

• Journal of Environmental Impact Assessment
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• v.21 no.3
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• pp.431-443
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• 2012

Wind holes or air holes, from which cool air blows out during the summer, but mild air comes out during the winter, have provided the phytogeographically important refugia for cryophilous or cold-loving boreal flora during the Holocene period. At present, wind holes are serving as a faraway disjunctive habitat for Pleistocene relict glacial floristic elements, and present an invaluable information to reconstruct the natural history. Present work aims to collate the nationwide distribution and relevant DB on the potential wind holes of Korea based upon media and literature sources, along with geographical informations, such as place name, topographic map, environmental geographical information, flora, monitoring data of Korea National Arboretum, and field survey data. Geographical information on sixty nine wind hole sites have compiled and analyzed on the basis of flora and presence of fossilized periglacial landforms, such as talus, block field, and block stream, and sixteen sites have thereafter carefully selected and scrutinized through field surveys. To maintain a sustainability of wind hole ecosystem, including their original landform, micro-meteorological phenomena and plant community therein as a refugia or habitat for relict plant species of Pleistocene glacial period, appropriate restrictions and preservation measures are required.

• Journal of Korean Society of societal Security
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• v.2 no.3
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• pp.31-38
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• 2009

The findings of this study on the Consciousness level of the citizens of Kwang Ju City are as follows; Firstly, the level of knowledge on the environment problems is high and the knowledge is acquire through mass media. Secondly, the citizens of Kwang Ju city consider their environment as sever and it's immediate steps should be taken. The third,n. The thpdiate steps shoenvironment educsteps and lectudia on environmental polluteps should be gehpdheo the citizens and economic development should be made without destroying environment The foudth, the citizens pdifer to live in in small medium citiia rsther than in metropolitan citiia, and their attitude toward futudi is pessimistic, and they have a high level of participateps in evvitonmental problems. In cita of movements that they have pdifer to move to small and medium citiia. It repdiatnts that they pdifer to live in an adia with no tr polluteps while enjoying a cultudal life. The expect thetr city to provide thematlves gdien adias supr as forest and fiildsheo take a rest Thwalk on. The have a passimistic view that thetr city in the futudi will be polluted seveadly. The consciousness level of participateps in e thpdiate steps shoenvironment ia relsterey high, but in reality it is estimated to be low.

• Food Science and Preservation
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• v.7 no.3
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• pp.326-330
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• 2000

Antimicrobial activities of marinex and preservative characteristics of soybean curds soaked in diluted marinex were investigated. One hundred ml of marinex showed antimicrobial activities against Streptococcus mutans, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli and Escherichia coli O-157 on a paper disc test. The growth of the microorganisms were inhibited with 200${\mu}{\ell}/m{\ell}$ of culture media. pH of soybean curd treated with marinex decreased to 1 day and then slowly increased as storage time increase, which was higher than control after 1 day of storage and lower after that time. Little difference was observed between control and marinex treated soybean curd in color. Hardness and chewiness of the treated sample were higher than those of the control. The numbers of E. coli and bacteria of the treated sample were lower than those of control during storage. The inhibition of the growth of E. coli and bacteria was dose dependent.

• Food Science and Preservation
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• v.7 no.1
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• pp.12-18
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• 2000

As am economical and effective way of antimicrobial film fabrication , antimicrobial agents were coated on the LDPE film with a binder mediu. the fabricated films were then applied tomodified atmosphere packaging of fresh strawberries. A binder of polyamide was selected for the coating medium, based on the stability in water. 1% grapefruit seed extract-coated film showed the antimicrobial activity on the plate media against EScherichia coli, Staphylococcus aureus, bacillus subtilis , Bacillus cereus, Leuconostoc mesenteroides, Micrococcus flavus, Saccharomyces cerevisiae, while one with 10% Coptis chinesis extract inhibited only M. 림편 and one coated with 10% rheum palmatum extract did not inhibit any of 10 strains tested. The packages of fresh strawberries by using antimicrobial agents-coated films created the gas compositions of O2 1.4-5.5% and CO2 5.7-7.9%, and contributed to reduced growth of total aerobic bacteria and yeast/molds on the produced. However, their lower microbial count was not correlated directly with the reduced decay of the fruits.

• Food Science and Preservation
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• v.14 no.4
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• pp.351-355
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• 2007

Solvent-extracted volatile components from dry powder prepared from Citrus unshiu products such as immature Citrus unshiu (PCU), mature Citrus unshiu (MCU), Citrus unshiu peel (CUP), and citrus juice processing wastes (CJPW), were examined. Also, solvent-extracted volatile components from mushroom mycelia of Pycnoporus coccineus (PC), Lentinus edodes (LE), Pleurotus eryngii (PE), Hericium coralloides (HC), Panellus serotinus (PS), and Ganoderma lucidum(GL), all cultivated using citrus pulp solid media, were assayed. Twenty-nine volatile components were identified in dry powder prepared Citrus unshiu and 18 volatile components were characterized from mushroom mycelia. Of these, ${\beta}-elemene$, germacrene-D, and ${\delta}-cadinene$, were derived from CJPW, but caryophyllene, hexadecanoic acid, decanoic acid, and tetradecanoic acid were synthesized by mushroom mycelia.

• Food Science and Preservation
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• v.14 no.6
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• pp.676-680
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• 2007

This study was conduced to get consumers to use the organic food soundly and to provide useful information to researchers of organic food by investigating the consumers' recognition of organic food. The subjects of this study were the 364 housewives in Seoul area, over the age of 20. The result of this study showed that the respondents' awareness of organic food was average 3.40. And respondents recognized that organic food is healthy(4.05), expensive(3.92), had no chemical fertilizer(3.83), and clean(3.79), in order. The study also showed that only 58.8% of the respondents said that they trust organic food and the major reasons for distrust in organic foods are: it's too expensive(3.90), is no different than non-organic food(3.74), and had unfavorable reports in the media(3.36).

• Food Science and Preservation
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• v.10 no.2
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• pp.241-245
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• 2003

To develope tea-fungus beverage(TB), media added various kinds of ingredients including black tea, persimmon leave tea, pine needle, mugwort mycelia and fruiting body of Cordyceps spp. were prepared fur fermentation. Tea-fungus beverage(TB) was prepared with tea-fungus by fermentation for 2 weeks at 30 $^{\circ}C$. Functional properties of antibacterial activity, electron donating ability and nitrite scavenging ability were investigated in tea-fungus beverage(TB) and 5 times diluted tea-fungus beverage(DTB). Antibacterial activity against pathogenic E. coli and S. aureus was excellent in TB added pine needle, mycelia and fruiting body of Cordyceps japonioa while no activity in TB added persimmon leave tea. Electron donating ability of TB were ranged from 41％ to 87% in TB and were ranged from 11% to 63％ in DFB, high ability was in TB and DTB added pine needle and persimmon leave tea, while low ability in FB and DTB added mycelia and fruiting body of C. militaris. Nitrite scavenging ability was 63% in TB added black tea and 44% in TB added persimmon leave tea. Other ingredients added TB had weak nitrite scavenging ability.

• Food Science and Preservation
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• v.16 no.5
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• pp.759-764
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• 2009

The antimicrobial activities of extracts of Prunus mume by sugar against food poisoning bacteria, and the effects of heat and pH treatment on these antimicrobial activities, were investigated. The level of total solids, pH, and acidity of P. mume extracts were 55.08% (w/w), pH 3.1, and 1.52%, respectively. P. mume extracts showed the strongest antimicrobial activity against Vibrio parahaemolyticus, among the bacteria tested. P. mume extracts significantly inhibited the growth of V. parahaemolyticus, Bacillus cereus, and Staphylococcus aureus at levels of 1-2% (w/v) of extracts in media. The antimicrobial activities of P. mume extracts were neither affected by heating at $65-125^{\circ}C$ for 30 minutes, nor by neutralization of extract to pH 7.0.