• 약학회지
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• 제57권2호
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• pp.150-159
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• 2013

A study was performed to identify current drug shortages, assess impact of drug shortages on public hospitals and patients, and investigate needs of pharmacists for a drug shortage list. An e-mail survey was sent to the pharmacists of 13 national public hospitals. Total 61.5% of public hospitals has 10 or fewer drugs a year in short supply. Shortages involved mood drugs, anti-tumor drugs, analgesics, antibiotics and etc. in 2012. Among them 75.0% was prescription drugs and the other 25.0% was non-prescription drugs. 79.2% was domestic products and 20.8% was imported drugs. Only 12.5% was injections. Less than 3 pharmacists usually spent within 3 hours managing one drug shortage. Since a single item for a certain medicine may raise risk of drug shortages, it's needed to consider developing manuals, laying up medicine stocks and holding plural medicines for drug shortages in public hospitals. Main information resources of drug shortages are wholesalers or manufacturers. But the information appeared to be not only inadequate but also too late for appropriate activities. A survey of pharmacists revealed that overall 84.6% of respondents were in need of the drug shortage list. They expected it to be conducted to take proper measures for the drug shortage and to improve patient healthcare outcome and convenience. This study will contribute to improving public health by promoting stable supply of drugs and repairing the information delivery system.

• 약학회지
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• 제49권5호
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• pp.399-404
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• 2005

To investigate drug interaction, 23,536 prescriptions published for 1 year were investigated with 'Drug Inter­action Fact 2002'. Dispensing records and a database file written in a local general hospital in South Korea were used as a sample. The number of total cases of drug interaction was 3,238 ($13.76\%$) out of 23,536 prescriptions. The incidence of drug interaction in each prescription the children, the adults, and the elderly were $1.33\%,\;10.97\%,\;25.50\%$, respectively. The incidences of drug interaction per each prescription were $22.03\%,\;20.52\%,\;0.51\%,\;and\;0.36\%$ in neurosurgery, internal med­icine, pediatrics, and orthopedics, respectively. In neurosurgery and internal medicine, risk-high drugs of drug interaction such as antihypertensive drugs, diuretics, and cimetidine were used very often in elderly. In this paper, several suggestions to reduce drug interaction were postulated with regard to the usage of analgesics, non-steroidal antiinflammatory drugs, and antibiotics.

• International journal of advanced smart convergence
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• 제10권3호
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• pp.66-71
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• 2021

Recent healthcare environments have characteristics of expanding the scope of healthcare-impacting healthcare, complexity resulting from diversification of components, and accelerating the pace of change. Drugs are used for the prevention, mitigation, and treatment of diseases, so they can inevitably cause harm, while they have efficacy and effectiveness, which are key elements of health recovery. Therefore, many countries regulate permits for safe and effective medicines, and also designate essential drugs directly related to life as pay targets and guarantee health insurance. Especially Pharmacist relying on manpower for composition medicine is liable for mal-manufacture due to combination of toxic medical substances or other chemical usage. In this paper, we focus on using Kiosk and Optical Character Recognition (OCR) for automated pharmacy to level up medical service and create labor friendly environment for pharmacist themselves through maintenance of prescription data and automated manufacturing solution. Presentation of drug substances and precautions will lead to efficient drug prescription and prevent misuse of information while auto manufacturing system efficiently maintain labor force and raise patient satisfaction level by reduction of waiting time.

• 한국의료질향상학회지
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• 제14권2호
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• pp.125-132
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• 2008

Background : The number of outpatient injected anticancer drug is increasing. and the pathway of prescribing, compounding, and injecting anticancer drug is processed very rapidly in out-patient department. Moreover, Dose of anticancer drug is often changed depending on side effect of patients. So we need more effective inspection of anticancer drug prescriptions. The purpose of this study was to analyze the prescription errors for anticancer drugs in Out-Patient Department and to suggest system to prevent them. Method : The study took place at Asan Medical Center from July to September 2007. The pharmacists performed inspection of anticancer drug prescriptions before compounding and injecting. We used protocol-based anticancer drug order program and Electronic Medical Record (EMR). Result : During the study period, we analyzed 4683 prescriptions for out-patient. And we detected 55 medication errors (1.2%). Most common errors included dosage above or below the correct ones (56.3%), followed by incorrect treatment duration. Because most of dosing errors were in the range of usual dosage, it was hard to detect them. So when inspecting the prescription, we considered the medical records of individual patients. As a result, we could raise the efficiency of intervention. Therefore inspection using EMR could possibly reduce the number of anticancer drug errors. Conclusion : we are preventing the medication errors on stability and dosage above or below the maximum therapeutic dose according to the previous inspection system. However most of dosing errors were in the range of usual dosage according to the result of this study. Because of there was interpatient variability of dosage depending adverse effect. For improvement of quality assurance, we suggest inspection system based on patient's medical history.

• 한국콘텐츠학회논문지
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• 제11권4호
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• pp.312-320
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• 2011

이 논문에서는 일개 POC(Point Of Care) 시스템을 사용하는 의료기관을 중심으로 의약품 처방조제지원 시스템(Clinical Decision Support System, CDSS)과 조직성과와의 관계를 규명하는 것에 목적을 두고 있다. 이를 위하여 정보시스템 평가요소에 대해 정의를 내리고, CDSS의 성과 평가 모형을 제시하여 설문조사 분석을 통해 의약품 처방조제지원시스템의 도입 효과를 밝히고자 하였다. 분석결과 시스템 품질을 제외하고는 각 평가 영역들 사이에 인과성이 존재하는 것으로 분석되었으며, 통계적으로 유의하게 지지되는 것으로 분석되었다. 평가모형 검증결과 의약품처방최적화를 위한 CDSS의 시스템 품질이 사용자 만족도에 영향을 미친다는 근거를 발견할 수 없었다. 그러나 정보품질이 사용자의 만족도에 긍정적인 영향을 미치며 사용자 만족은 조직성과에 긍정적인 영향을 미치는 것으로 나타났다.

• 한국임상약학회지
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• 제32권4호
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• pp.313-320
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• 2022

Background: Serotonin syndrome is a life-threatening disease if not appropriately treated. This study aimed to investigate the prescription status of contraindicated drug combinations that cause serotonin syndrome and identify the related factors. Methods: A cross-sectional study was conducted using nationwide claims data. Adult patients taking serotonergic drugs with Parkinson's disease or mental disorders were selected. Based on international medical databases (MDBs) and the Korean Drug Utilization Review (DUR), the status of prescribing contraindicated drug combinations that induce serotonin syndrome, the related factors, and the difference between international MDBs and the Korean DUR were analyzed. Results: Of the 49,773 study subjects, 163 (0.3%) were prescribed contraindicated serotonergic drug combinations based on international MDBs, and among them, only 105 (64.4%) were contraindicated by the Korean DUR. Positive influencing factors for prescribing contraindicated drug combinations include patient age between 65 and 74 and physician's specialties (neurologists, and orthopedists). Negative influencing factors were physician's specialty (internists) and medical institution (primary institutions). Conclusion: Despite the implementation of DUR, 3 out of 1,000 study subjects received contraindicated drug combinations that caused serotonin syndrome. Hence, it is necessary to comply with the DUR and improve it in accordance with international MDBs.

• 한국임상약학회지
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• 제21권2호
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• pp.106-114
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• 2011

1) 제주도 사업의 경우에 고양시보다 의료기관의 참여도가 높았는데 이것은 처방내에서 혹은 동일 의사의 처방내에서 병용금기나 중복의 발생을 줄이는 노력을 기울인 사실을 의미하였다. 빈도수에 있어서 병용금기는 고양시에서 처방전 1만 건당 0.45건 발생에서 제주도는 0건으로, 중복의 경우는 고양시에서 1만 건당 197건에서 제주도는 23건으로 감소하였다. 2) 하지만 제주도의 의료기관 참여도가 높음에도 불구하고 다른 의사 처방과의 점검에서는 병용금기 및 중복이 뚜렷이 감소하지 않았다. 병용금기의 발생은 고양시에서 1만 건당 4.95건에서 제주도의 경우 4.16건으로, 중복의 경우에 고양시의 경우 1만 건당 426건에서 제주도는 381건으로 감소하였지만 그 차이는 동일 의사 점검에서와 같은 뚜렷한 감소가 아닌 미세한 것이었다. 3) 두 지역을 통합하여 계산하였을 때 병용금기 발생의 동일 의사 점검: 다른 의사 점검의 비(比)(ratio)는 1:23으로 계산되었다. 4) 고양시 지역에서 중복의 발생은 동일 의사 점검: 다른 의사 점검의 비(比)(ratio)는 1: 2.12이었으며 제주도의 경우 그 비(比)(ratio)는 1:16.5이다. 5) 병용금기나 중복의 발생 문제 대부분이 다른 의사가 발행한 복수 처방에 의한 의약품의 병용에서 비롯하는 문제이며 이것은 의도하거나 인지하지 못한다는 점에서 단순 다제병용보다 심각한 문제를 포함할 수 있다. 6) 연구의 발견점은 의료 및 약사용 측면에서 통합성을 높이는 정책대안의 시급성을 시사하고 있으며 DUR제도의 확대강화와 단골약국 이용을 통하여 이러한 목표를 향한 정책을 지지해주는 결과라고 볼 수 있다.

• 경영과학
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• 제28권2호
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• pp.93-103
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• 2011

This paper has aimed to identify marketing variables which affect physicians' prescription of drug. Based on a literature review this paper derives the three factors (indirect commercial source, direct commercial source, academic information source) of information sources that physicians rely on for medicines, the three factors (research supporting activity, marketing supporting activity, medicine information supporting activity) of promotion activities physicians prefer, and the four factors (indirect quality of medicine, direct quality of medicine, experience of using medicine, price and design of medicine) of prescription criteria physicians use. Then it investigates using canonical correlation analysis whether or not physicians' prescriptions are affected by the information sources, the promotion activities, and the type of physicians. From the canonical correlation analysis this paper derives the meaningful three canonical functions of prescription for drugs. The first function explains the prescription which is insensitive to marketing activities, the second function does the prescription which is sensitive to them, and the final function does the prescription which is not affected by them.

• 약학회지
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• 제55권6호
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• pp.500-509
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• 2011

This study was to identify factors influencing drug compliance based on the subjects' interview regarding community pharmacy utilization for 2 weeks, in 2005 KNHANES. Good compliance was regarded as important factors in improving the effectiveness and minimizing adverse drug reaction, resulting in reducing the medical costs. 83% of total 11,208 pharmacy visits in 7,066 subjects showed good compliance. Good satisfaction for pharmacist's medication counseling (OR=2.23, 95% CI 1.92-2.58), higher out-of-pocket money (OR=1.32, 95% CI 1.14-1.54), and users of prescription drugs than non-prescription (OR=2.21, 95% CI 1.91-2.57) drugs were significant factors for better compliance. Disease of nervous system and mental and behavioral disorders showed lower drug compliance.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2006년도 춘계종합학술대회
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• pp.1055-1059
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• 2006

최근 인터넷 기술이 비약적으로 발전하는 추세에 부응하여 의료사업분야에서도 전자처방전 및 처방 EDI 시스템이 병 의원과 약국간에 이루어지고 있다. 그러나 현재 대부분의 병 의원들의 전산화구축 현황을 볼 때 전산화시스템을 도입하지 않은 병 의원이 많고 워드프로세스로 발급하거나 수기로 처방하는 현실이다. 이런 병 의원들을 웹을 통한 처방전관리를 하게 된다면 데이터의 호환성 및 약국과의 연계를 통해 처방에 대한 검증까지 가능할 것이다. 본 논문에서 의료자료의 처방전표준양식을 설계하고 이용자가 처방전발급을 위해 별도의 환경설정을 하지 않고 운영환경에 무관하도록 XML 웹기반의 처방전양식표준을 개발하였고 이용자의 인터페이스를 편리하게 하면서 프로그램 유지보수가 용이하도록 데이터베이스의 검색결과를 XML형태로 작성하도록 구현하였다.