• The Journal of Korean Physical Therapy
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• v.15 no.4
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• pp.398-411
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• 2003

The purpose of this study was to investigate the effects of circuit weight training(CWT) on isokinetic muscle strength and body composition in elderly. The subjects who engaged in this experiment exercised at $40\%$ of 1-RM, 12 repetitions, followed by 15 sec as the subject moved to the each break training program which was consist of the circuit of 10 stations performed on 3 set a day, circuits 3 days a week during 10 weeks. The assessment of isokinetic factor was in concentric flexors and extensors of right and left knee joint. Tests were performed on the Cybex 770 Isokinetic Dynamometer and body composition were estimated the three parts of chest, abdomen and anterior thigh by using skinfold caliper, calculated the average and followed by Seri and Brozek way. Statistical analysis were performed using analysis of variance paired t-test, accepting level for all significant was above ${\alpha}=.05$ and ${\alpha}=.01$. Following is as a result of 10 weeks circuit weight training. 1. At the $60_{\circ}$ /sec, the right and left knee isokinetic concentric flexors and extensors peak torque increased significantly(p<.01). 2. At the $180_{\circ}$ /sec, the right and left knee isokinetic concentric flexors and extensors peak torque increased significantly(p<.01). 3. At the $60_{\circ}$ /sec, the right and left knee isokenetic concentric flexors and extensors average power increased significantly(p<.05, p<.01) and at the $180_{\circ}$ /sec, the right extensors didn't show any statistical significant. 4. At the $60_{\circ}$ /sec, the right and left knee Isokinetic concentric flexors and extensors total work increased significantly(p<.05, p<.01) but at the $180_{\circ}$ /sec right concentric flexors didn't show any statistical significant. 5. The body composition changed significantly(p<.01). These results suggest that 10 weeks circuit weight training increases the peak torque, average power, total work significantly and decreases the $\%$body fat significantly.

• Journal of Oriental Neuropsychiatry
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• v.13 no.2
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• pp.41-56
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• 2002

The Analysis of MMPI and Clinical Study was carried out the 28 patients with somatoform disorder and depressive disorder who were treated in Daejeon University Oriental Hospital from 19 June 2001 to 17 April 2002. The results were summarized as follows. 1. The ratio of female was higher, especially in the depressive disorder, the ratio of female was higher and in the age distribution, the 40 aged were higher frequence. 2. In the somatoform disorder, symptoms appeared to be busy in physical symptoms, and they were in descending order the digestive organs system, head and face portion and musculoskeletal system symptoms, in the depressive disorder, appeared to be busy in psychosomatic system symptoms and in the prescription drugs, soyosan(逍遙散), punsimkiyyin(分心氣飮) were used to be busy. 3. In the scales of L, F, K, somatoform disorder showed ${\wedge}$ typed graph, and depressive disorder showed ${\vee}$ typed graph. 4. In the somatoform disorder, scales of Hs, Hy, D, Pa were higher, and in the depressive disorder, scales of Hy, Hs, Pd, D were higher. 5. In the scales of Hs, D, Hy, somatoform disorder showed ${\vee}$ typed graph, and depressive disorder showed/typed graph. 6. the average of T-scores and the ratio over 65 score and 70 score showed common distribution.

• The Korean Journal of Food And Nutrition
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• v.25 no.3
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• pp.513-520
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• 2012

This research was planned and executed to evaluate how the composition of Yack-sun tea can affect the health conditions of people who are suffering from diet-related such as being overweight, are obese and have hyperlipidemia, by taking Yack-sun tea in a form of a nutritional supplement with our daily meals. We produced Kangjieum with Lycium chinense Mill., Polygonum multflorum Thunb, Cassia tora L., Crataegus pinnatifida Bge and Salvia miltiorrhiza Bge. Thus, we approach of oriental diet therapy area research of Kangjieum and analysis proximate composition, water soluble antioxidant content. The content(%, dry basis) of total carbohydrate was 60.23%, crude protein was 18.18%, crude ash was 11.36% and crude fat was 10.23% in Kangjieum. Total water soluble antioxidant content was 1.027 ${\mu}g/m{\ell}$ of Kangjieum. We think that scientific and objective evaluation was done on the components of the Kangjieum prescription. This basic data could help guide the application of oriental medicinal resources into other foods and serve as a stepping-stone for use of Kangjieum in the burgeoning field of nutraceutical foods. Last, the scientific effects of oriental medicinal foods developed according to oriental medicinal theory. This theory is believed to be essential for government policy development concerning validation of medicinal effects and assessment, with the aim of fostering systematic development and providing guidance to food development in the interest of national health.

• Herbal Formula Science
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• v.20 no.2
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• pp.37-46
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• 2012

Objectives : Oyaksungi-san(Wuyaoshunqisan) has been used for treatment of stroke and rheumatoid arthritis in Korea. In this study, a simple and accurate high-performance liquid chromatography(HPLC) method was established for simultaneous determination of six main components, liquiritin, ferulic acid, naringin, hesperidin, neohesperidin, and glycyrrhizin in Oyaksungi-san, a traditional Korean herbal prescription. Methods : The analytical column for separation of six constituents was used a Gemini $C_{18}$ column maintained at $40^{\circ}C$. The mobile phase consisted of two solvent systems, 1.0% (v/v) acetic acid in $H_2O$ (A) and 1.0% (v/v) acetic acid in acetonitrile (B) by gradient flow. The flow rate was 1.0 mL/min and the detector was a photodiode array (PDA) set at 254 nm for glycyrrhizin, 280 nm for liquiritin, naringin, hesperidin, and neohesperidin, and 320 nm for ferulic acid. Results : Calibration curves were acquired with $r^2$ values ${\geq}0.9998$. The results of recovery test were 91.58%-105.90% with a relative standard deviations (RSDs, %) value less than 2.0%. The values of RSD for intra- and inter-day precision were 0.03%-1.72% and 0.03%-1.63%, respectively. The contents of the six compounds in Oyaksungi-san were 0.33-9.30 mg/g. Conclusions : The newly established HPLC method will be helpful to improve quality control of Oyaksungi-san.

• Journal of the Korean Applied Science and Technology
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• v.35 no.2
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• pp.399-411
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• 2018

Taekwon dancing was a program developed to popularize Taekwondo. The purpose of this study is to examine the research trend of Taekwondo dancing to understand academic value and purpose. To accomplish this goal, this study analyzed 46 article published in 26 journals. Data analysis was performed using the IBM SPSS 23.0 program, which was divided into research subjects, research methods, and research subjects. The results were as follows. First, in the research area, the study was consistently published in exercise physiology / prescription area, and recently studies have been published in the field of sports pedagogy. Second, quantitative research was conducted more than qualitative research in research methods. In the quantitative research, the research that verified the difference between the groups was published the most. in the qualitative research, literature research was the most. Finally, in the study subjects, most studies were conducted on people, by subgroup, the study was published in many order of adult, elderly, middle school students. In the analysis of the data, literature, web-site news and so on were analyzed, other study was analyzed the program system in computer games.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.1
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• pp.1-14
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• 2006

Objective : As prevalence of atopic dermatitis(AD) rises and medicine of atopic dematitis develops, the methods of measurement for atopic dermatitis have developed. Therefore, we aimed to establish a new sconring system in oriental medicine for a childhood atopic dematitis, by comparison, analysis of various sconing systems. Method : We searched for the data related to severity sconing systems of atopic dermatitis in Entrez PubMed on abroad thesis and KISS(Korenstdued Information Service System) on domestic thesis from 1990 to 2005. Result : Severity sconing systems for atopic dermatitis satisfy validity, reliability, sensitivity of change and verification of this. The essential items of severity sconing systems are extent, intensity and subjective symptoms. The lesion is divided into 9 areas(head and neck, upper limbs, elbow, hands, trunk, hip and inguinal, lower limbs, knee, feet). The items of intensity are erythema, oedema and induration and papulation, oozing and weeping and erosion, excorition, scaling, lichenification. The subjective symptom is pruritis, evaluated according to sleep loss and obstruction of play and study. The extent and intensity is evaluated in combination. We suggested that extent and intensity occupied for 70% and subject symptoms accounted for 30% of total score.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1370-1374
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• 2005

The Tosyl-JM3 (TJM3) is a modified compound from one of 1,2,3,4-Tetra- hydroisoquinoline (THIQ) derivatives. The THIQs include potent cytotoxic agents that display a range of anti-tumor activities, antimicrobial activity, and other biological properties. In this study, we investigated the effect of TJM3 on the cytotoxicity, induction of apoptosis in human promyelocytic leukemia cells (HL-60 cells). TJM3 showed a significant cytotoxic activity in HL-60 cells (IC50 = approximately $60{\mu}g/m{\ell}$) after a 24 hr incubation. Treatment of HL-60 cells with TJM3 exhibited several features of apoptosis, including formation of DNA ladders in agarose gel electrophoresis, morphological changes of HL-60 cells with DAPI stain. Here we observed that TJM3 caused a decrease of procaspase-3 protein. Further molecular analysis demonstrated that TJM3 led to cleavage of poly(ADP-ribose) polymerase (PARP) by western blot and increase of hypodiploid (Sub-G1) population in the flow cytometric analysis. In conclusion, these above results indicate that TJM3 dramatically suppresses HL-60 cell growth and induces apoptosis. These data may support a possibility for the use of TJM3 in the prevention and treatment of leukemia.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.3
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• pp.772-778
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• 2005

The chloromethyl-2-dihydroxyphosphinyl-6,7-dimethoxy-1,2,3,4-tetrahydro- isoquinoline (CDDT) is a newly synthesized derivative from 1,2,3,4-Tetra- hydroisoquinoline (THIQ). The THIQs include potent cytotoxic agents that display a range of antitumor activities, antimicrobial activity, and other biological properties. In this study, we investigated the effect of CDDT on the cytotoxicity, induction of apoptosis in human promyelocytic leukemia cells (HL-60 cells). CDDT showed a significant cytotoxic activity in HL-60 cells ($IC_{50}$ = approximately $37\;{\mu}g/ml$) at a 24 hr incubation. Treatment of HL-60 cells with CDDT displayed several features of apoptosis, including formation of DNA ladders in agarose gel electrophoresis, morphological changes of HL-60 cells with DAPI stain. Here we observed that CDDT caused activation of caspase-3, caspase-8, and caspase-9. The most efficacious time on the activation of caspases-3 was achieved at 12 hr. Further molecular analysis demonstrated that CDDT led to cleavage of poly(ADP-ribose) polymerase (PARP), increase of hypodiploid (Sub-G1) population in the flow cytometric analysis. In conclusion, these above results indicate that CDDT dramatically suppresses HL-60 cell growth by activation of caspase-3 with caspase-8, -9 activity. These data may support a pivotal mechanism for the use of CDDT in the prevention and treatment of leukemia.

• YAKHAK HOEJI
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• v.59 no.5
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• pp.235-244
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• 2015

The goal of this study is to help for the utilization the national pharmacists test through the analysis of item development management to the foreign pharmacists examination. The United States is going to NABP (National Association of Boards of Pharmacy) initiative under the curriculum in question on the basis of this assessment and develop standards and unified, systematic system to conduct tests pharmacist. Practice oriented (patient scenario, the participation of a pharmacist or perform work, clinical practice) examination is doing in Canada, The UK is asking the for more than 70 percent and the prescription needed for actual calculation in practice prior to testing program, and by the including that allows references use. Our country may introduce the job as a clinical pharmacist, positively. Item management system is integrated into four regions based on the six-year curriculum should be done in harmony proportion of each region. Integration of fusion of each region in accordance with the duties should be come out. It has gradually been able to item management system developed by the United States or Canada. This item notice pharmacist judging the results of the work must be carried out for management upgrading to a form of management with an emphasis on clinical practice in developed countries. Foundation design, development, production and management and test after actively reviewing ways to improve management system for to management systems, a pharmacist to improve the quality of the national examination could be contributing are involved.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.11 no.2
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• pp.59-67
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• 2007

Objectives: Pathogenesis treats cause of disease. Pyungweesan is pathogenic prescription of indigestion. This study researched for developing questionnaire of prescribing pyungweesan. Methods: Korean medical doctor classified the patients into two group, pyungweesan symptom group and non pyungweesan symptom group. After that, each group responsed to the questionnaire. We tested for both the reliability and validity of the questionnaire. For validity test, we compared the sum, average and standard deviation of 20 items of pyungweesan symptom group with those of non-pyungweesan symptom group through independent sample t-test, For reliability test, we computerized crohnbach's a value of the items. Results: The developed questionnaire showed remarkable reliability. (Cronbach's ${\alpha}$ =0.854) There were a significant differences on the sum of the 20 items and each 19 item's average and standard deviation, except 1 item; Do you have an irregular discharge from the womb? Conclusions: Based on the results of the above analysis, the korean medical doctor will make an effort to apply the pyungweesan questionnaire clinically. In the future, the additional research is needed.