• 산업과 과학
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• 제2권1호
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• pp.8-14
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• 2023

본 연구에서는 흑마늘 제조 시 발생하는 부산물을 이용하여 기능성 사료 첨가제룰 개발하기 위한 사전 실험으로 수행되었다. 흑마늘박의 항산화 활성과 면역증강 활성을 측정하였으며 흑마늘박의 항산화 활성을 측정한 결과 흑마늘박이 항산화 활성이 있는 것으로 나타났다. 실험에 사용된 시료중 흑마늘박을 포함한 식물성 시료의 면역증강 활성을 실험하기 위해 Nitric oxide(NO) assay 실험을 한 결과 식물성 추출물인 흑마늘박, 섬쑥부쟁이, MIX가 최고 농도에서 LPS(100%)대비 각각 흑마늘박(69.4%), 섬쑥부쟁이(35.9%), MIX(45.3%)의 NO를 생성하였다. 따라서, 흑마늘박이 항염증 효과를 함유하고 있고 흑마늘박과 섬쑥부쟁이의 최적의 혼합비를 선정한다면 항염증 효과를 함유하고 있는 사료 첨가제로써 충분한 가치가 있을 것으로 사료된다.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2000년도 제28회 학술심포지엄
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• pp.3-8
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• 2000

The complete genome sequence of a Gram-positive bacterium .Bacillus subtilis has recently been reported and it is now clear that more than 50% of its ORFs have no known function (1). To study the global gene expression in B. subtilis at single gene resolution, we have tested the glass DNA microarrays in a step-wise fashion. As a preliminary experiment, we have created arrays of PCR products for 14 ORF whose transcription patterns have been well established through transcriptional mapping analysis. We measured changes in mRNA transcript levels between early exponential and stationary phase by hybridizing fluorescently labeled cDNA (with Cy3-UTP and Cy5-UTP) onto the array. We then compared the microarray data to confirm that the transcription patterns of these genes are well consistent with the known Northern analysis data. Since the preliminary test has been successful, we scaled up the experiments to ${\sim}$94% of the 4,100 annotated ORFs for the complete genome sequence of B. subtilis. Using this whole genomic microarray, we searched genes that are catabolite-repressive and those that are under the control of ${\sigma}^{Y}$, one of the functionally unknown ECF sigma factors. From these results, we here report that we have established DNA microarray techniques that are applicable for the whole genome of B. subtilis.

• Journal of Advanced Marine Engineering and Technology
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• 제38권9호
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• pp.1163-1169
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• 2014

$CO_2$ 가스 기포 탐지 기술 개발을 위한 예비연구로 인위적으로 발생시킨 수층의 $CO_2$ 가스 기포 플룸을 다중빔음향측심기, 단일빔음향측심기 그리고 천부지층탐사기(SBP)를 이용해서 탐지 비교하였다. 인위적으로 발생시킨 기포의 상승속도는 가스 탱크에서 압축된 가스의 강제적인 누출이 영향을 미쳐 기존 자료보다 높게 나타나는 것으로 판단된다. 다중빔음향측심기는 단일빔 음향장비에 비하여 넓은 범위를 탐지할 수 있고 가스 누출 위치 및 수층에서 가스 플룸의 3차원적인 정보를 제공하고 있다. 따라서 다중빔음향측심기는 단일빔의 음향장비 보다 더 뚜렷한 가스 플룸을 탐지할 수 있으나, 상호보완적으로 동시에 운영하면 보다 효과적인 탐지기술을 확립할 수 있다. 향후, 본 연구는 특정가스의 음향학적 특징을 파악하여 정량적, 정성적 탐지 기술 향상에 기여하고자 한다.

• 대한전자공학회논문지
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• 제19권1호
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• pp.20-28
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• 1982

본 논문에서는 국내에서 최초로 기니아 픽 내이의 와우각에서 소리에 대한 전기신호(cochlear microphonics: CM)를 측정하였다. 이때 정현파음에 대한 cochlear microphonics의 진폭을 변수로 해서 물리적 화학적 상태변화에 의한 청감의 동특성을 분석하였다. 끝으로 동신호를 이용한 전자청력재생방법에 관한 기초실험을 시행하였다. 그 결자 10마리 기니아 픽에게 물리적 상태변화로 100dB white noise음향을 가했을 때 정기파음에 대한 cochlear microphonics는 일단 감소된 레벨을 나타내다가 거의 본래의 크기로 복귀되었다. 화학적 상태변화로 NaCl결정을 와우각에 투여한 경우는 정기파음에 대한 cochlear microphonics가 초기의 증가, 감소, 증가, 감소의 패턴을 보였다. 소리에 대해 cochlear microphonics형태로 전기신호를 발생시켜서 중이가 손상된 기니아 픽내이에 위치한 electrode에 직접 가해준 결과 동물의 reflex반응을 얻었다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.523-523
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• 2012

As the wafer geometric requirements continuously complicated and minutes in tens of nanometers, the expectation of real-time add-on sensors for in-situ plasma process monitoring is rapidly increasing. Various industry applications, utilizing plasma impedance monitor (PIM) and optical emission spectroscopy (OES), on etch end point detection, etch chemistry investigation, health monitoring, fault detection and classification, and advanced process control are good examples. However, process monitoring in semiconductor manufacturing industry requires non-invasiveness. The hypothesis behind the optical monitoring of plasma induced ion current is for the monitoring of plasma induced charging damage in non-invasive optical way. In plasma dielectric via etching, the bombardment of reactive ions on exposed conductor patterns may induce electrical current. Induced electrical charge can further flow down to device level, and accumulated charges in the consecutive plasma processes during back-end metallization can create plasma induced charging damage to shift the threshold voltage of device. As a preliminary research for the hypothesis, we performed two phases experiment to measure the plasma induced current in etch environmental condition. We fabricated electrical test circuits to convert induced current to flickering frequency of LED output, and the flickering frequency was measured by high speed optical plasma monitoring system (OPMS) in 10 kHz. Current-frequency calibration was done in offline by applying stepwise current increase while LED flickering was measured. Once the performance of the test circuits was evaluated, a metal pad for collecting ion bombardment during plasma etch condition was placed inside etch chamber, and the LED output frequency was measured in real-time. It was successful to acquire high speed optical emission data acquisition in 10 kHz. Offline measurement with the test circuitry was satisfactory, and we are continuously investigating the potential of real-time in-situ plasma induce current measurement via OPMS.

• 대한임상검사과학회지
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• 제50권2호
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• pp.164-169
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• 2018

The development of teaching models to strengthen practical education and actively participate in the classes of students is now required in recent education situations. This study examined the participation and satisfaction level of students' classes after applying a teaching model-integrated hospital and school laboratory (named L2L). A total of 33 students who took the subject of a clinical microbiology experiments were involved in this study. Each group representative participating in a pre-class field exercise in the hospital microbiology laboratory was asked to conduct the experiment. After applying the L2L teaching models, the academic self-efficacy ($2.87{\pm}0.58{\rightarrow}3.38{\pm}0.55$), class participation ($2.60{\pm}0.92{\rightarrow}3.62{\pm}0.78$), and class satisfaction ($2.48{\pm}1.01{\rightarrow}3.85{\pm}0.87$) increased significantly (P<0.05). This means that pre-class field exercises created interest in the student's class and boosted self-confidence, leading to increased participation and satisfaction for the class. In conclusion, the L2L teaching model is an effective teaching method to enhance the practical training for preliminary clinical laboratory technologists.

• 천문학논총
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• 제24권1호
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• pp.65-81
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• 2009

We present the performance test results of VLBI Correlation Subsystem (VCS) trial product which was being developed for 1 year from August 2007. It is a core component of Korea-Japan Joint VLBI Correlator (KJJVC). The aim for developing VCS trial product is to improve the performance of VCS main product to reduce the efforts and cost, and to solve the design problems by performing the preliminary test of the manufactured trial product. The function of VCS trial product is that it is able to process the 2 stations-1 baseline, 8 Gbps/station speed, 1.2 Gbps output speed with FX-type. VCS trial product consists of Read Data Control Board (RDC), Fourier Transform Board (FTB), and Correlation and Accumulation Board (CAB). Almost main functions are integrated in the FTB and CAB board. In order to confirm the performance of VCS trial product functions, the spectral analysis, delay compensation and correlation processing experiments were carried out by using simulation and real observation data. We found that the overflow problem of re-quantization after FFT processing was occurred in the delay compensation experiment. We confirmed that this problem was caused by valid bit-expression of the re-quantized data. To solve this problem, the novel method will be applied to VCS main product. The effectiveness of VCS trial product has been verified through the preliminary experimental results, but the overflow problem was occurred.

• 태양에너지
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• 제11권2호
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• pp.70-76
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• 1991

본 실험에서는 태양광의 photon energy를 활용한 물분해 수소제조 연구를 위하여 일차적으로 $TiO_2$ 광전극의 제조와 함께 전기화학적 특성관찰의 기초실험을 수행하였다. $TiO_2$ anatase 분말을 원형으로 molding 한 후 $1250^{\circ}C$에서 sintering하여 n형 반도체 전극을 제조하였으며, titanium plate를 직접 funace내에서 $800^{\circ}C$의 공기 및 산소 분위기 속에서 각각 산화막을 생성시켰다. 각 전극들의 XRD pattern을 관찰한 결과 rutile $TiO_2$ 성질의 표면구조를 지니고 있었으며, 표면상태를 광학 현미경으로 관찰하였다. 선택된 $TiO_2$ 전극의 전기적 특성을 조사하기 위하여 두가지 농도의 NaOH electrolyser내에서, dark상태 그리고 Xenon lamp를 활용한 illuminated상태에 대하여 각각의 I-E 특성을 Potentiostat을 이동하여 관찰분석하였다.

• 컴퓨터교육학회논문지
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• 제10권6호
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• pp.11-18
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• 2007

본 논문에서 구현된 논리회로 가상실험실은 원리이해를 위한 개념학습실과 가상 디지털 키트에 의한 가상실험실의 두 단계로 설계하였다. 개념학습실에서 학습자는 디지털 논리회로에 대한 중요한 원리나 의미를 쉽게 이해할 수 있도록 하였다. 가상실험실에서는 가상 브레드보드에서 회로를 결선하여 입력전압을 인가하여 출력신호를 측정한 다음 가상실험데이터와 비교하여 서버로 전송한다. 가상실험실에서 수행된 모든 실험활동은 데이터베이스에 저장되어 개인정보와 함께 예비보고서의 형태로 제공되어 교수자는 학습자가 얼마나 회로동작에 대해 잘 이해하였는가를 점검할 수 있도록 하였다. 마지막으로 제안된 가상실험시스템의 유효성을 입증하기 위해 한 학기 동안 실험 중에 발생한 실제 장비의 파손율과 학생들의 성취도를 5개의 설문을 통해 조사하여 분석하였다.

• 한국전문물리치료학회지
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• 제13권4호
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• pp.79-86
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• 2006

The purpose of the current experiment was to describe interlimb coordination when swing limb conditions are being manipulated by constraining step length or by adding a 5 or 10 pound weight to the swing limb distally. Subjects were asked to begin walking with the right limb to land on the primary target (normal step length) that is 10 cm in diameter. However, if, during movement, the light was illuminated, then the subject had to step on one of the secondary targets (long and short step length). These three step length conditions were repeated while wearing a 5 pound ankle weight and then when wearing a 10 pound ankle weight. Ground reaction force (GRF) data indicated that there were changes in the forces and slopes of the swing and stance Fx GRFs. Long stepping subjects had to increase the propulsive force required to increase step length. Consequently, swing and stance toe-off greatly increased in the long step length condition. Short step length subjects had to adequately adjust step length, which decreased the speed of gait initiation. Loading the swing limb decreased the force and slope of the swing limb. Swing and stance toe-off was longest for the long step length condition, but there was a small difference of temporal events between no weight and weight condition. It appears that subjects modulated GRFs and temporal events differently to achieve the peak acceleration force of the swing and stance limb in response to different tasks. The findings from the current study provide preliminary data, which can be used to further investigate how we modulate forces during voluntary movement from a quiet stance. This information may be important if we are to use this or a similar task to evaluate gait patterns of the elderly and patient populations.