• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.119-130
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• 1996

We review the factors which regulate the depth and composition of the human airway surface liquid (ASL). These include secretion from airway submucosal glands, ion and fluid transport across the surface epithelium, goblet cell discharge, surface tension and transepithelial gradients in osmotic and hydrostatic pressure. We describe recent experiments in which we have used low temperature scanning electron microscopy of rapidly frozen specimens to detect changes in depth of ASL in response to submucosal gland stimulation. We also present preliminary data in which X-ray microanalysis of frozen specimens has been used to determine the elemental composition of ASL.

• Design & Manufacturing
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• 제16권2호
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• pp.7-12
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• 2022

The purpose of this study is to develop an evaluation method for online design education. Online education has established itself as the primary form in the educational field, however, there are unsatisfactory response from instructors and students due to rapid conversion of online education. Due to the transition of educational method, online class contents have become optimized and online educational experiences became accumulated. However, clear education criteria is essential. This study states importance of two parts: establishing an evaluation system based on design thinking for online design education and finding appropriate online platforms for interaction between instructors and students. The research results provide implications for ensuring the efficiency of design education and are expected to contribute significantly to the future education field.

• 한국산업보건학회지
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• 제22권3호
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• pp.175-183
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• 2012

Objectives: This study developed a harmonized method for risk assessment based on the Hazard & Risk Evaluation of Chemicals (HREC) according to the Industrial Safety and Health Act (ISHA). Methods: Three preliminary studies, performed during 2010 and 2011 by the Occupational Safety and Health Research Institute and three academic research groups, were compared. The differences in risk assessment, especially in the dose-response assessment method, were analyzed. A new harmonized method for dose-response assessment was suggested and its applicability for the HREC was examined. Results: Considering the various steps of each dose-response assessment, the equivalent steps in quantitative correction, uncertainty factor 2 (UF2) for intra-species uncertainty, and UF3 for the experimental period in the uncertainty correction were relatively high. Using our new method, the total correction values (quantitative correction plus uncertainty correction) ranged from 72~15,789 to 30~60, and the ratio of the threshold limit value (TLV) to the reference concentration decreased from 12.8~1900 to 5.4~11.8. Furthermore, when we performed risk characterization by our new method, hazard quotient (HQ) values for chloroethylene, epichlorohydrin, and barium sulfate became 3.0, 14.1, and 1.13 respectively, whereas three previous studies reported HQ values of 7.1, 4580, and 87.3 considering reasonable maximum exposure (RME) conditions. HQs of the three chemicals were calculated to be 0.6, 2.4, and 0.1 respectively, when compared to their TLVs. Conclusions: Our new method could be applicable for the HREC because the total correction values and the ratio of TLVs were within reasonable ranges. It is also recommended that additional risk management measures be applied for epichlorohydrin, for which the HQ values were greater than 1 when compared with both reference values and the TLV. Our proposed method could be used to harmonize dose-response assessment methods for the implementation of risk assessment based on the HREC according to ISHA.

• International Journal of Aeronautical and Space Sciences
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• 제12권2호
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• pp.156-162
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• 2011

The preliminary design stage of helicopters consists of various operations and in each operation design several detailed analysis tasks are needed. The analysis tasks include performance and the required power estimation. In helicopter design, those are usually carried out by adopting the momentum theory. In this paper, an explicit form of computational analysis based on the blade element theory and uniform/non-uniform inflow model is developed. The other motivation of the present development is to obtain trim and required power estimation for various helicopter configurations. Sectional and hub loads, power, trim, and flapping equations are derived by using a symbolic tool. Iterative computations are carried out till convergence is achieved in the blade response, inflow, and trim. The predictions regarding the trim and power estimation turn out to be correlated well with the experimental results. The effect of inflow is further investigated. It is found that the present prediction for the lateral cyclic pitch angle is improved with the non-uniform inflow model as compared to that by the uniform inflow model. The presently improved trim and power estimation will be useful for future helicopter sizing and performance analysis.

• 환경정책연구
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• 제12권2호
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• pp.17-32
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• 2013

최근 인류가 초래한 지구의 온난화로 인하여 기온이 상승하고 이의 직접적인 반응으로 수온 증가가 감지되고 있다. 기온변화가 하천의 수질과 생태 환경에 미치는 영향을 추정하기 위해서는 수온 상승의 시기와 하천 어종에 대한 이해가 필요한데 이를 위하여 미래의 수온을 예측할 필요가 있다. 이에 하나의 사전연구로서 기온-수온 관계에 대하여 분석해 보았다. 2009년에서 2011년까지 3년 동안 환경부의 수질자동관측소에서 관측한 최소 873개에서 최대 1083개의 일 관측 자료를 바탕으로 자기상관관계와 교차상관관계를 조사해 본 결과 0.9 이상의 높은 상관관계를 보였다. 또 지체시간이 10일 미만에서는 기온의 자기 상관 계수가 수온의 가기 상관 계수보다 더 높은 것으로 나타났다. 관측자료의 이력현상을 분석하기 위하여 상승기와 하강기로 나누었는데, 관측지점에 따라서는 강한 이력현상을 보이는 지점도 발견되었다. 결국 기온-수온 관계를 구축함에 계절적인 이력현상이 고려되어야 정확도를 높일 수 있음을 유추할 수 있다.

• 성인간호학회지
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• 제16권1호
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• pp.37-48
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• 2004

Purpose: The purpose of this preliminary study was to develop and evaluate the effects of East-West Self-help program for Rehabilitation of post-stroke clients. Method: This program is developed through literature review, survey and seminar. The program is consisted of six sessions twice a week for 6 weeks. This program is composed of health education on stroke, exercise, oriental nursing interventions, and therapeutic recreation. The outcomes have been evaluated on the basis of perceived health status, self-efficacy, U/E function, ADLs and subjective response. Result: 1) After the 6 week program, the perceived health status had improved and the score of rehabilitation self-efficacy increased significantly. 2) After the 6 week program, the score of BADL increased significantly, but, the score of IADL was not statistically significant. 3) After the 6 week program, the amount of use and quality of movement of the affected U/E were increased significantly. 4) All of the participants showed satisfaction with this program. Conclusion: Considering these research results, the program is effective in improving functional abilities and self-management ability. Therefore this program could be continuously developed and implemented as a community based self-helf group program for post-stroke clients.

• 한국항행학회논문지
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• 제16권1호
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• pp.1-7
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• 2012

본 연구에서는 쿼드로터형 비행체 개발을 위한 선행연구로서 1축 자세 제어장비를 개발하고, 시뮬레이션과 실험을 수행하였다. 두 개의 모터와 프로펠러로 구성된 시소형 1축 자세 제어장비가 제작되었고, 추력 시험을 통해 공력 파라메터를 도출하였다. Matlab/Simulink를 이용하여 시스템의 응답을 추정하였고, 자세 센서와 자세 제어 컴퓨터를 탑재하여 실험을 수행하였다. 시뮬레이션과 실험 데이터를 비교하여 실험 시 발생하는 정상상태 오차에 대한 원인을 파악하고, 사용된 자세알고리즘과 자세 제어 컴퓨터에 대한 성능 검증하였다. 본 과정을 통해, 쿼드로터형 무인항공기 자세 제어를 위한 선행 필수 기초자료를 획득하였다.

• 한국항공우주학회지
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• 제44권5호
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• pp.416-422
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• 2016

본 논문에서는 연세대학교 천문우주학과 우주비행제어연구실에서 개발 중인 인공위성 편대비행 테스트베드에 대한 예비 성능분석 결과를 제시하였다. 동역학 모델에 포함되지 않은 동특성과 측정 잡음 등에 의한 불확실성의 영향을 받는 반작용 휠의 응답 성능을 향상시키기 위하여 간단한 1차 선형시스템을 기준 모델로 하는 적응제어기를 설계하였다. 또한 자세 측정값에 잡음이 포함된 환경에서도 원활한 제어를 수행하기 위해 최소제곱법 기반의 실시간 파라미터 추정기법을 이용하여 관성모멘트를 추정하였다. 수치 시뮬레이션과 하드웨어 실험을 통해 설계된 모델 기준 적응제어기의 적합성과 향후 적용가능성을 검토하였고, 전 시간에 걸친 자세 추적오차가 $0.25^{\circ}$ 이내에 머무는 것을 확인하였다. 하지만 하드웨어 실험을 통해 드러난 제어 입력에 대한 데드존의 영향을 줄이기 위해서는 인공위성 시뮬레이터의 설계 변경이 필요하다고 판단된다.

• 한국전문물리치료학회지
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• 제13권4호
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• pp.79-86
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• 2006

The purpose of the current experiment was to describe interlimb coordination when swing limb conditions are being manipulated by constraining step length or by adding a 5 or 10 pound weight to the swing limb distally. Subjects were asked to begin walking with the right limb to land on the primary target (normal step length) that is 10 cm in diameter. However, if, during movement, the light was illuminated, then the subject had to step on one of the secondary targets (long and short step length). These three step length conditions were repeated while wearing a 5 pound ankle weight and then when wearing a 10 pound ankle weight. Ground reaction force (GRF) data indicated that there were changes in the forces and slopes of the swing and stance Fx GRFs. Long stepping subjects had to increase the propulsive force required to increase step length. Consequently, swing and stance toe-off greatly increased in the long step length condition. Short step length subjects had to adequately adjust step length, which decreased the speed of gait initiation. Loading the swing limb decreased the force and slope of the swing limb. Swing and stance toe-off was longest for the long step length condition, but there was a small difference of temporal events between no weight and weight condition. It appears that subjects modulated GRFs and temporal events differently to achieve the peak acceleration force of the swing and stance limb in response to different tasks. The findings from the current study provide preliminary data, which can be used to further investigate how we modulate forces during voluntary movement from a quiet stance. This information may be important if we are to use this or a similar task to evaluate gait patterns of the elderly and patient populations.

• 한국의료질향상학회지
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• 제23권2호
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• pp.37-54
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• 2017

Objectives: The purpose of this preliminary study was to identify the nurses' perception regarding disclosure of patient safety incidents (DPSI) and to evaluate the effectiveness of education for DPSI. Methods: DPSI education was conducted for nurses majoring in clinical nurse specialist at an university. Before and after the education, the nurses made a questionnaire to evaluate the perception of DPSI. The questionnaires were divided into four categories: first, overall perception of the DPSI; second, recognition evaluation of the DPSI using hypothetical case, third, opinion on legal and nonlegal measures for facilitating the DPSI; and fourth, socio-demographic factors. The Wilcoxon signed rank test was performed on the DPSI questionnaire response to compare the perceptions before and after the education. Results: A total of 10 nurses participated in the education. DPSI education showed the possibility of improving the overall perception, necessity, effect, obstacle, and promotion method of DPSI, although there were also several responses where there was no statistical significance. In particular, DPSI education led to statistically significance change in the perception of obstacles for DPSI. For example, the number of respondents who agreed to the item "DPSI will increase the incidence of medical lawsuits." was 7 before education but decreased to 3 after education (P-value: .025) Furthermore, nurses' perception of DPSI from this study was generally positive regardless of education. Conclusion:In the future, it will be necessary to carry out DPSI education and training and to evaluate its effectiveness for more nurses.