• Title/Summary/Keyword: Pregnancy and delivery

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Principles and Methods for the Reproductive-toxicological Evaluation of New Drug Candidates (의약후보물질의 생식독성평가 원칙 및 방법)

  • 정문구;김종춘
    • Toxicological Research
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    • v.16 no.3
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    • pp.229-238
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    • 2000
  • The purpose of reproductive toxicity studies is to evaluate all effects resulting from paternal or maternal exposure that interfere with conception, development, birth, and maturation of offspring. In 1966, the US Food and Drug Administration (US FDA) published guidelines for a three-segment study for drug testing to examine adverse effects on fertility and pregnancy. Three segments were proposed: Segment I, Study of Fertility and General Reproductive Performance, to provide information on breeding, fertility, nidation, parturition, neonatal effects and lactation: Segment II, Teratological study, to provide information on embryo toxicity and teratogenicity: and Segment III. perinatal and Postnatal Study, to provide information on late fetal development, labour and delivery, neonatal viability, and growth and lactation. The classic guideline is still used to this day with only monor modification throughout the world. In the present review, the principles and methods of reproductive toxicity studies are discussed with special attention given to scientific issues.

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Decision-making process and satisfaction of pregnant women for delivery method (임산부의 분만방법 결정과정과 만족도)

  • Jun, Hae-Ri;Park, Jung-Han;Park, Soon-Woo;Huh, Chang-Kyu;Hwang, Soon-Gu
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.4 s.63
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    • pp.751-769
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    • 1998
  • This study was conducted to assess the attitude of pregnant women toward delivery method, understanding of the reason for determining her own delivery method, participation in decision-making process and satisfaction with delivery method after labor. Study subjects were 693 pregnant women who had visited obstetric clinic for prenatal care in the last month of pregnancy in one general hospital and one obstetrics-gynecology specialty hospital in Taegu city from February 1 to March 31 in 1998. A questionnaire was administered before and after labor and a telephone interview was done one month after labor. Proportion of women who had health education and/or counselling about delivery method during prenatal care was 24.0% and this proportion was higher for women who had previous c-section(35.5%) than others. Women thought vaginal delivery is better than c-section for both maternal and baby's health regardless of previous delivery method. About 90% of primipara and multiparous women who had previous vaginal delivery wanted vaginal delivery for the index birth, while 85.6% of multiparous women who had previous c-section wanted repeat c-section. Reasons for choosing c-section in pregnant women who preferred vaginal delivery before labor were recommendation of doctors(81.9%), recommendation of husband (0.8%), agreement between doctor and pregnant woman(4.7%), and mother's demand (12.6%). Reasons for choosing vaginal delivery were mother's demand(30.6%) and no indication for c-section(67.2%). Reasons for choosing c-section in pregnant women who preferred c-section before labor were recommendation of doctors(76.2%), mother's demand(20.0%), recommendation of husband(1.3%), and agreement between doctor and pregnant woman(2.5%). Of the pregnant women who had c-section, by doctor's recommendation, the proportion of women who had heard detailed explanation about reason for c-section by doctor was 55.1%. Mother's statement about the reason for c-section was consistent with the medical record in 75.9% . However, over 5% points disparities were shown between mother's statement and medical record in cases of the repeat c-section and mother's demand. In primipara and multiparous women who had previous vaginal delivery, the delivery method for index birth had statistically significant association with the preference of delivery method before labor(p<0.05). All of the women who had previous c-section had delivered the index baby by c-section. Among mothers who had delivered the index baby vaginally, 84.9% of them were satisfied with their delivery method immediately after labor and 85.1% at 1 month after labor. However, mothers who had c-section stated that they are satisfied with c-section in 44.6% immediately after labor and 42.0% at 1 month after labor. Preferred delivery method for the next birth had statistically significant association with delivery method for the index birth both immediately after labor and in 1 month after labor. The proportion of mothers who prefer vaginal delivery for the next birth increased with the degree of satisfaction with the vaginal delivery for the index birth but the proportion of mothers who prefer c-section for the next birth was high and they did not change significantly with the degree of satisfaction with the c-section for the index birth. These results suggest that the current high technology-based, physician-centered prenatal and partritional cares need to be reoriented to the basic preventive and promotive technology-based, and mother-fetus-centered care. It is also suggested that active involvement of pregnant woman in decision-making process for the delivery method will increase the rate of vaginal birth after c-section and decrease c-section rate and improve the degree of maternal satisfaction after delivery.

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- The Content Analysis of Childrearing Articles in the Korea Central Daily Newpapers : Focusing on Dong-a and Cho-seun ilbo from 1920's to 1970's. - (한국신문에 실린 아동양육에 관한 기사내용분석(II) - 1920년대부터 1970년대의 동아.조선일보를 중심으로 -)

  • 신양재
    • Journal of the Korean Home Economics Association
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    • v.31 no.2
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    • pp.159-175
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    • 1993
  • The purpose of this study is to explor the ideas about childrearing represented in the Korean central daily newspapers. The method used for this study is the content analysis and the data are articles of Dong-a ilbo and Cho-seun ilbo from 1920's to 1970's. It is found that the contents of childrearing articles were concerned on childrearing practices conformable with social change for industrial capitalization during twentieth century of Korea. These articles dealt with problems of practices in the pregnancy-delivery, nurturing, teaching, disciplining and interfacing between home and institutional education of school. Especially, these article put great emphasis on preservation of health and hygiene of child, interfacing between child and school education, and meeting martial needs of child. Also they made the issuse of adult-centered manners in the child-rearing.

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A Study of Heo Jun's 『Eonhaetaesanjipyo』 (허준(許浚)의 『언해태산집요(諺解胎産集要)』에 대(對)한 연구(硏究))

  • Jeong, Eun-ah;Kim, Nam-Il
    • The Journal of Korean Medical History
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    • v.15 no.2
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    • pp.83-100
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    • 2002
  • The Oriental Obstetrics and Gynecology is a branch of the Oriental Medicine that treat of physiological and pathological diseases of the female. The origin of the Oriental Obstetrics and Gynecology begins at the pregnancy and delivery of the women. Therefore it has significant meanings about the birth of human beings. The field of this study has been very important to the Oriental Medicine. Accordingly the present writer is planning to study of the level of the Oriental Obstetrics and Gynecology and its effects in those days, through Heo Jun(許浚)'s "Eonhaetaesanjipyo" ("諺解胎産集要") that is a work of the Oriental Obstetrics and Gynecology books in the history of Korean Oriental Medicine.

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Content Analysis of Mother's Pregnance.Childbirth & Child Rearing on PC Communication (PC 통신에 나타난 어머니의 임신.출산 및 얻아 양육에 관한 내용분석)

  • 김영주
    • Journal of the Korean Home Economics Association
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    • v.39 no.9
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    • pp.1-14
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    • 2001
  • The purpose of this study was to explore the ideas about childrearing represented on the cuber space. The method used for this study is the content analysis and the data are articles on the Hitel bulletin board during 1 year. It is found that these articles dealt with problems of practices in the pregnancy-delivery, nurturing, teaching and interfacing between home and social institutions. Especially these articles put great emphasis on nurturing. For example, there are many articles about caring, development, health and hygiene of child. And from 1st to 6th month, there are many articles about nurturing. After 7th month, many articles about teaching and interfacing between home and social institutions are appeared. So from these results we might conclude that many functions of the home are transmitted to society too early.

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A Cabe of Congenital Malaria (선천성 말라리아 1례)

  • 박국인;박희대
    • Parasites, Hosts and Diseases
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    • v.22 no.1
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    • pp.72-77
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    • 1984
  • A case of congenital malaria infection has been studied in a 46-day old female Korean infant. Her mother suffered from malaria infection during pregnancy in Uppervolta, Africa, and returned to Korea at the 9th month of gestation for delivery. At 39 days of age, the clinical features characterized by fever, irritability, pallor, jaundice and hepatosplenomegaly were developed. The laboratory data revealed a hemolytic anemia with thronbocytopenia, hyperbilirubinemia and increased hepatic enzyme values. A peripheral blood smear demonstrated intraerythrocytic malarial parasites and gametocytes of Plasmodium falciparum. She was successfully treated with quinine solfate (25mg/kg/day in three doses for 5 days) and trimethoprimejsulfamethoxazole (8mg/kg/day in two doses for 5 days) orally, and repeated blood smear had been negative for malaria. This report also signifies the first description of congenital malaria in Korea imported from Uppervolta in Africa. A brief review of related literature was made.

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Spontaneous Uterine Rupture after Uterine Artery Embolization for the Treatment of Uterine Myomas

  • Kim, Sang Joon;Kim, A Mi;Kim, Tae Young;Kim, Jong Woon;Kim, Yoon Ha
    • Perinatology
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    • v.29 no.4
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    • pp.195-197
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    • 2018
  • As intervention techniques have been developed recently, minimal invasive treatment for uterine myoma using uterine artery embolization is receiving attention increasingly. Uterine rupture occurs rarely, but once it occurs, it may cause fatal results in both mother and fetus. Although the relationship between uterine artery embolization for treatment of uterine myoma and uterine rupture has not been clearly revealed yet, a case implying that the embolization for treatment of uterine myoma can be a risk factor of uterine rupture like previous caesarian delivery or myomectomy.

Content Analysis of Mother's Role in Korean Biographies (우리나라 위인전에 나타난 어머니 역할 내용분석)

  • Kim, Young-Joo
    • Journal of Families and Better Life
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    • v.27 no.2
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    • pp.243-254
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    • 2009
  • The purpose of this study was to investigate the mother' role appeared in Korean biographies. The method used for this study was the content analysis of the context related with mothering in Korean biographies. The categories for content analysis were pregnancy-delivery, nurturing, teaching, disciplining, interfacing between home and social institutions and counselling. It was found that the most frequent mother' role appeared in Korean biographies was nurturing role such as to care development, health and hygiene of children. And the second frequent mother's role in Korean biographies was disciplining role such as to internalization of social roles. The third role was teaching. These results have been discussed in the light of former studies, and the limits of study method also have been discussed.

Socio-Cultural Mechanism of Infertile Women's Experience and Nursing (불임경험의 사회적 기제(Mechanism)와 간호)

  • Cho, Nam-Ok;Park, Young-Sook
    • Women's Health Nursing
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    • v.2 no.2
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    • pp.216-229
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    • 1996
  • Pregnancy and delivery are the God's blessing as well as the right of all married women. But, these are agonizing events for the infertile women. Therefore, supportive nursing care for the infertile women is crucial in the process of diagnosis and treatment of infertility. The introduction of In Vitro Fertilization is a solution for infertility. But we take it serious that such socio-cultural factors as patriarchism, sex role, and motherhood are negatively influencing infertility women's experiences. Thus, nurses who take care of the infertile women need to have feministic perspectives as well as medical information, and expertise so that they could reach a comprehensive understanding on infertile women's experiences.

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A Clinical Study on the Postpartum Depression Treated by Gami-Boheo-tang (가미보허탕(加味補虛湯)으로 치료한 산후우울증 1예에 대한 임상보고)

  • Lee, Jin-A;Ban, Hye-Ran;Cho, Seong-Hee
    • Herbal Formula Science
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    • v.13 no.1
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    • pp.223-233
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    • 2005
  • As woman receive many stress during pregnancy and delivery, they happen to contract to psychopathy like a postpartum depression. Postpartum depression is a serious problem if they are not treated early enough the unhappy seriousness can be resulted. A 32-yeared-old female patient with postpartum depression was taken to Dongshin University oriental medical hospital on April, 28, 2003. We diagnosed this patient as postpartum depression, which originated from and efficiency of vital energy and blood. We treated this postpartum depression patient with herb medicine(Cami-Boheo-tang),acupuncture, moxibustion, and psychical therapy. After the oriental medical treatments, the patient was improved in all complains of the postpartum disease. After this, further study and approach will be needed about the disease of the postpartum depression.

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