• International Journal of Contents
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• 제10권2호
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• pp.37-41
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• 2014

This study defined the pre-elderly as middle age people from 50 to 59. Because it is difficult to produce a design to satisfy the pre-elderly without deeply understanding them, their financial and physical characteristics and persona-based scenario method was studied. An experimental study about persona based scenario method was conducted, and as a result, the types of personas found were as follows: 1) Users enjoy the same games online and offline. 2) Users enjoy playing alone on the computer. 3) Users prefer games that end quickly with win or loss. Writing the situation scenario for each type, the pre-elderly's problems and needs occurring while they play web board games were obtained. The obtained user requests were as follows: users would like the level of difficulty to be simpler in the game of baduk; users wanted unlimited credit and refrainment from using English words in go-Stop; and there were simple comments about game screen design.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 제39회 하계학술대회
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• pp.2303-2304
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• 2008

It is believed that the pre-flashover phenomena would play a very important role in the procedure of the flashover in the interface between the insulators and vacuum. This paper is mainly concerned on the pre-flashover phenomena of Alumina insulators in vacuum. There are 24 different types of alumina insulators were tested with a 0.7/4 ${\mu}s$ pulsed voltage under a $1{\times}10^{-4}Pa$ vacuum. The observed pre-flashover phenomena were classified and the pre-flashover characteristics were concluded. It is useful to study further on the flashover mechanism in vacuum.

• 한국보육지원학회지
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• 제18권1호
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• pp.71-90
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• 2022

Objective: This study examined the experiences of pre-service Early Childhood teachers who participated in major-associated autonomous club activities. Methods: Participants were 31 students of the Department of Child Care at A University located in Gyeonggi-do, who participated in a major-associated autonomous music club activity. A content analysis was conducted to examine the meaning of the participation experience of pre-service Early Childhood teachers. Qualitative content analysis was the best method to analyze the meaning of their experience while participating in the activities. Results: The meaning of the experience of music club activities was organized into three categories: "enjoying abundant college life," "growing as a competent childcare teacher," and "being a responsible member of a community." Conclusion/Implications: The results show that pre-service Early Childhood teacher's participation in the activities of major-associated autonomous clubs has a positive impact on desirable changes in college life and adaptation to the department and on the growth of future professional Early Childhood teachers.

• 천문학회보
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• 제5권
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• pp.23.1-23.1
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• 1980

• 대한약학회:학술대회논문집
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• 대한약학회 2000년도 NEW STRATEGY FOR DRUG DEVELOPMENT IN POST-GENOMIC ERA(대한약학회)
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• pp.177.1-177.1
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• 2000

• 생명과학회지
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• 제26권11호
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• pp.1330-1335
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• 2016

조릿대 속 식물의 잎은 한의학적으로 염증, 해열, 이뇨 관련 질환 치료에 사용되어 왔다. 제주조릿대는 제주도 한라산 일대에서만 분포되어있는 토착식물이다. 본 연구에서는 제주조릿대 잎 추출물의 산업적 활용 효율을 높이기 위해 추출방법에 따른 식물화합물의 함량과 그 생리 활성을 비교함으로써 기능성이 강화된 식물화합물 다량함유 추출물(phytochemical-rich extract; PRE)의 제조방법을 개발하였다. PRE는 열수추출물과 알코올추출물에 비하여 높은 폴리페놀 함량을 나타내었고, 조릿대 주요성분인 p-coumaric acid (44.10 mg/g)와 tricin (5.35 mg/g)의 함량은 열추추출물(p-coumaric 23.39 mg/g, tricin 0.18 mg/g)과 알코올 추출물(p-coumaric 10.8 mg/g, tricin 0.38 mg/g)에 비해 매우 높았다. RPE는 다른 추출물에 비해 총 폴리페놀 함량과 항산화 활성[1,1-diphenyl-2-picrylhydrazy(DPPH) 소거활성, 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) 소거활성, nitric oxide(NO) 소거활성, xanthine oxidase 저해활성]이 가장 높았다. 그리고 RPE는 LPS로 자극시킨 RAW 264.7 세포에서 NO 생성($IC_{50}=59.1{\mu}g/ml$)과 혈액 암(HL-60) 세포의 성장을 효과적으로 억제하였다. 본 연구결과는 PRE가 식물화합물을 다량 함유하고 있어 항산화 및 항염소재로서 활용가치가 있음을 제시해 준다.

• 대한간호학회지
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• 제30권4호
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• pp.956-966
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• 2000

The purpose of this study was to examine the comparative between depression and stress related to life events among women in the menopausal stage. Menopausal stages were divided into two groups: Pre and post-menopausal stages. The degree of depression and stress related to life events between pre and post menopausal women were compared to each other. Women, aged between 41 and 59 years, answered self-reported questionnaires which included Zung's depression scale and life events scale modified by Lee (1984). Findings were as follows; 1) The mean score of premenopausal women who experienced depression was 39.66, and for post-menopausal women the score was 41.45. There was no significant differences in depression levels between pre and post menopausal group.s (t=-1.55, p=.122). 2) Menopausal women experienced low levels of stress related to life events. There were no significant differences between pre and post menopausal groups(t=.527, p>.05). Both pre and post menopausal groups were highly concerned about education issues of their children and disharmony between couples. 3) There was a significant relationship between depression and stress related to life events among post-menopausal groups (r=.22, p<.01). Based on the findings of this study, the menopausal depression was associated with stress related to life events, especially among post-menopausal women. Feelings of lost fertility and feminine attributies result in menopausal depression, which is significantly correlated with women's negative perception of their life events. Therefore, nursing intervention needs to develop to help reduce the levels of depression and overcome their negative perception of the menopausal experience. Nurses should develop nursing strategies to help menopausal women to have positive perceptions and enhance quality of life by assisting their adaptability to physiological and psychological changes related to menopause.

• 재무관리연구
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• 제23권1호
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• pp.135-163
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• 2006

본 연구는 기업공개(IPO)전 은행과의 관계가 최초공모주 가격결정에 어떠한 영향을 미치는가를 실증분석하였다. 본 연구에서는 2001년 1월부터 2003년 9월까지를 대상기간으로 하여 코스닥시장에 신규 상장된 총 343개 기업을 표본으로 삼았다. 미국의 경우를 연구한 James and Wier(l990)의 결과와는 달리 본 논문에서는 우리나라의 경우 기업공개전에 형성된 은행관계가 오히려 기업공개 후 초기 초과수익률의 규모를 증가시키는 역할을 하고 있음을 발견하였다. 또한 은행 및 벤처캐피탈로부터 중복 지원을 받은 기업들의 초기 초과수익률이 가장 높게 나타나고, 두 금융기관의 지원이 전혀 없는 기업들의 초기 초과수익률이 가장 낮게 나타나고 있음을 발견하였다. 이러한 IPO 초기성과는 은행차입금의존도가 높을수록 그리고 청약경쟁률이 높을수록 크게 나타나는 경향이 있었다. 본 연구의 결과는 우리나라 IPO시장에서 기업공개 직후 관찰되는 정(+)의 초기성과는 대부분 과도한 수요로 인하여 높게 형성되는 시장가격 때문이라는 최문수 (1999)의 연구결과와 전반적으로 일치하고 있다.

• 생약학회지
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• 제26권4호
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• pp.390-410
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• 1995

This study was attempted to investigate the effects of Composite Preparation (Samulchungkan-Tang) extract (SCTE), Scutellarias Radix extract (SRE), Artemisiae iwayomogii Herba extract (AIHE), Artemisia capillaris Flos extract (ACFE), Paeaniae Radix extract (PRE) and Gardeniae Fructus extract (GFE) on the activities of GOT, GPT, ALP and LDH, and Content of total cholesterol in serum of $CCl_4$ and ${_D}-galactosamime$ intoxicated rats, and bile flow in rats. 1) In $CCl_4-intoxicated$ rats-The activities of S-GOT and S-GPT which were elevated by $CCl_4$ were significantly decreased in dose of SCTE 450 mg/kg, ACFE 600 mg/kg and GFE 300 mg/kg, respectively as compared to $CCl_4$ intoxicated rats. ALP activity increased by $CC1_4-treatment$ was markedly decreased in dose of SCTE 450 mg and 600 mg/kg, SRE 400 mg/kg, AIHE 400 mg/kg, ACFE 600 mg/kg and PRE 300 mg/kg, and LDH activity in SCTE 450 mg and 600 mg/kg, ACFE 600 mg/kg and GFE 300 mg/kg, respectively compared to $CCl_4$ treated rates. ACFE 400 mg/kg and PRE 300 mg/kg decreased the content of total cholesterol increased by $CCl_4$, the liver weight in all sample administered groups was decreased significantly as compared to $CCl_4$ treated groups. 2) In ${_D}-galactosamine$ intoxicated rats-Sample of SCTE 450 mg and 600 mg/kg, SRE 400 mg/kg, AIHF 400 mg and 600 mg/kg, ACFE 600 mg/kg, PRE 300 mg/kg and GFE 300 mg and 500 mg/kg decreased the activities of S-GPT, ALP and LDH which was increased by ${_D}-galactosamine$ intoxication, compared to ${_D}-galactosamine$ intoxicated groups. In S-GOT activity elevated by ${_D}-galactosamine$ was significantly decreased by SCTE 450 mg/kg, ACFE 600mg/kg, AIHE 600 mg/kg, PRE 300 mg/kg, GFE 300 mg and 500 mg/kg. However, SCTE 600 mg/kg, SRE 400 mg/kg, and AIHE 400 mg/kg were not effected significantly. 3) In bile secretion-SCTE 450 mg and 600 mg/kg, ACFE 600 mg/kg and GFE 500mg/kg increased significantly the amount of bile secretion as compared to normal groups, but AIHE 400 mg/kg, SRE 400 mg/kg, and PRE 300 mg/kg did not effected significantiy.

• Journal of Korean Biological Nursing Science
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• 제12권2호
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• pp.114-126
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• 2010

Purpose: To examine the levels of the disease-related knowledge and educational demands of pre-dialysis, chronic renal failure patients at different GFRs and stages. Methods: This study used a cross-sectional survey and aimed at 116 pre-dialysis, chronic renal failure patients, who were registered and received regular treatment from December 1 to December 31, 2009 at the nephrology departments of tertiary medical centers in Seoul. Stages were classified into Stage 3, 4 and 5 depending on GFR ranges. To measure the levels of knowledge and educational demands, the tool, which were first invented by Young Ae Lim (1996) and then modified by Hyo Sun Lim (2005) to adjust the knowledge and educational demands measuring tool for hemodialysis patients to pre-dialysis patients with chronic renal failure, was used. Collected data was analyzed with the SPSS WIN 12.0 program (average, standard deviation, Pearson's correlation coefficient, t-test and ANOVA). Results: There was a significant difference in the disease-related knowledge levels of the subjects at each stage (F=24.41, p=.000). The Scheffe post hoc test confirmed that patients at higher stages had higher levels of knowledge of their disease. Also, although the results showed that patients at higher stages had higher educational demands, there was no significant difference among the groups (F=1.259, p=.288). Conclusion: As patients have different levels of knowledge of the disease and educational demands depending on their stages, it is important to develop and use a systematic education program that reflects the demands and levels of patients at each stage in order to help pre-dialysis patients with chronic renal failure with self-management and improve their quality of life.