• 제목/요약/키워드: Pre-rejection

검색결과 64건 처리시간 0.028초

국소적 방사선조사의 신장이식 후 거부반응에 대한 예방적 및 치료적 효과 (The Effect of Local Irradiation in Prevention and Reversal of Acute Rejection of Transplanted Kidney with High-dose Steroid Pulse)

  • 김일한;하성환;박찬일;김수태
    • Radiation Oncology Journal
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    • 제4권1호
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    • pp.15-20
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    • 1986
  • 1979년부터 1984년까지 이식신에 대하여 39회의 국소적 방사선조사가 서울대학교병원 치료방사선과에서 시행되었다. 10회는 예방적으로, 29회는 치료적으로 시행되었고 전체 환자 수는 29명이었다. 방사선조사는 1일 150cGy로 격일간 450cGy를 원칙으로 하였으며 methylprednisolone(Solumedrol)과 동시 병용되었다. 면역억제제로서 prednisone과 Imuran은 이식 후 계속 투여되었다. 방사선조사 시기는 예방목적일 경우에는 이식수술 후 1, 3, 5일에, 치료목적인 경우에는 거부반응의 진단 후 어느정도 시간간격을 두고 시행되었는데, 간격은 개인차이가 있었다. 10예의 예방적조사를 받은 이식신의 8예가 추후 거부반응이 출현하였으며, 이식 후 15개월 후에 기능적 생존을 보인 예는 없어서 예방적조사 효과는 회의적이었다. 치료목적으로 처음 조사받은 21예의 거부반응 회복율은 $71\%$였고, 방사선조사 전 혈청 크레아티닌이 $5.5mg\%$이하일 경우는 $93\%,\; 5.5mg\%$이상일 경우는 $17\%$였다(P<0.01). 극복이 안된 경우 재차 방사선조사에 대한 효과는 초회효과보다 열등하였다. 거부반응이 회복된 경우에 $47\%$가 재차 거부반응이 출현하였다. 거부반응에 대한 처음 방사선조사 후 이식신의 기능적 생존율은 방사선조사 후 6개월, 1년, 2년 및 3년에 각각 $70\%,\;65\%$$54\%$였고, 방사선조사 전 혈청 크레아티닌 수준, 거부반응 진단 후 방사선조사까지의 경과시간 및 방사선조사후의 반응 등이 이식신의 기능적 생존에 유의한 영향을 미침을 알 수 있었다(P<0.001). 따라서 방사선조사로 효과를 얻기 위하여는 거부반응으로 인한 이식신 파괴가 한계수준을 넘지 않는 범위 내에서 시행함이 필요함을 알 수 있었다. 이 효과는 Solumedrol과 병용된 결과이므로 방사선조사의 상대적 기여도를 밝히는 것은 어려웠다.

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중국 법원의 중재판정 승인 및 집행에서 공공질서 적용에 관한 연구 (A Study on the Recognition and Enforcement of Arbitral Awards Applied Public Policy by Chinese Court)

  • 하현수
    • 한국중재학회지:중재연구
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    • 제21권3호
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    • pp.115-136
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    • 2011
  • In the past, Chinese arbitral system and Chinese arbitral associations were avoided by international society due to the cases which Chinese court rejected the recognition and enforcement of foreign arbitral awards based on rural protection. Especially Chinese court adjudicated to reject the recognition and enforcement of arbitral awards by interpreting public policy broadly. The abuse of public policy by court threats the existence of commercial arbitration system. Under this awareness, the author figured out Chinese court shows what kind of attitude about public policy of Chinese court in the present through analyzing the cases about rejection of enforcement in Chinese arbitral awards in order to analyze whether Chinese court still maintain the negative attitude like past or there exist changes with public policy which is one of the rejection reasons of recognition and enforcement in foreign arbitral awards as the central figure. Chinese court behaved in an uncooperative attitude about arbitral awards like that it reached a verdict to reject the enforcement of arbitral awards by reason of violation in public policy about several foreign arbitral awards at the beginning stage of establishing arbitration law. However, the situation of abuse in public policy was improved a lot by Chinese prime court which enforces pre-inspection system about judgment of rejection of enforcement in arbitral awards. So, there is no case about rejecting the approval and enforcement of arbitral awards by reason of violation in public policy by Chinese court except Yongning Co. case. Moreover, Chinese court got the trust and support from other countries through reinforcement of applied standard. However, Chinese court had been expressed concern from international society because they highly applied public policy and rejected to enforce arbitral awards in the recent case of Yongning Co.. Therefore, this study examined whether it is appropriate to apply public policy of Chinese court in the case of Yongning Co., and then I concluded that. Although Yongning Co. case is the first case which Chinese prime court agrees with public policy by reason of rejection of approval and enforcement in foreign arbitral awards, in my opinion, it doesn't mean that Chinese court has fundamental change in basic attitude and position about the approval and enforcement of foreign arbitral awards. Chinese court keeps the cautious uses of public policy in legal judgment of foreign arbitral awards and it looks like implementing the obligation in regulation of New York Convention sincerely.

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전자기장의 분광 에너지에 기반한 MT 및 GDS 자료의 전처리 기법 연구 (Pre-screening technique for MT and GDS data processing based on the spectral power of Electromagnetic field)

  • 양준모;권병두
    • 한국지구물리탐사학회:학술대회논문집
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    • 한국지구물리탐사학회 2006년도 공동학술대회 논문집
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    • pp.253-258
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    • 2006
  • 한반도는 고도의 산업화와 도시화로 인해 깨끗한 MT 및 GDS 자료를 획득하기 매우 어렵다. 이러한 환경에서는 적당한 신호 대 잡음비를 가지는 자료를 선별하는 전처리 과정이 필수적이다. 본 연구에서는 전자기장의 분광에너지에 기반한 자동 전처리 과정(RMP)을 한반도의 현실적인 상황을 고려하여 수정하였고, 이를 한반도 내륙에서 획득된 총 7 측점의 MT 자료에 적용하였다. 전반적으로, RMP 기법은 주기 10초 대역 부근에서 주파수에 따른 전기비저항과 위상의 연결성을 상당히 향상시켰다. 또한 RMP 기법에 의한 결과는 수작업으로 편집된 기존의 처리 결과와도 거의 유사였고, 특히 전기 비저항의 연결성면에서 그 우수성이 확인되었다.

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생체신 공여자의 수술전후 관리에 대한 연구 -윤리적인 측면을 중심으로- (Pre and Post Operative management of Living Kidney donor - Focus on bioethical aspect -)

  • 김명희
    • 기본간호학회지
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    • 제2권2호
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    • pp.139-154
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    • 1995
  • The purpose of this study was presented basic data for management of living kidney donor to make bioethical decision. The research subjects were the documents and progress notes of Doctor's and Nurses in medical records related to kidney donation and nephrectomy of 20 kidney donors who received nephretomy at 4 general hospitals in Pusan. The result of this study, a desirable documents to help the living kidney donor might include following : 1st, identification of the donor and the guardian. 2nd, confirmation of the intension of kidney donor which is based on humanity or not and 3rd, a written oath about Nephrectomy. Especially it is more desirable to participate of paramedical personnels such as the religious, the social workers, the counsellors, and etc when assess the motivation of kidney donor and to use of a formulated visual educational materials about renal angiography and nephrectomy which required written consent of kidney donor. Further more, the donor should be educated sufficiently about the kidney itself and procedure for nephrectomy-the anatomical position of kidney, the function of the kidney, the operative maneaver, pre and post operative complication, the prevention of the complication, the possiblity of rejection phenomenon and loss of the transplanted kidney etc. In conclusion, medical team members for kidney transplantation must suggest not only physical problem but also psychological problem And the educated donor ought to have enough time before a making decision and all these process should be recorded in medical records

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User Experience and the Multi-Stage Adoption of Mobile Apps

  • Kim, Ambrose;Kim, Kyoung-jae
    • Journal of Information Technology Applications and Management
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    • 제21권2호
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    • pp.49-79
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    • 2014
  • The adoption of technology has always been of interest to academicians and practitioners of the field of Management Information System. This is so because without proper and adequate adoption, technology-no matter how beneficial or advanced it may be-will be of little value to users. Numerous researches, such as the researches of the Technology Acceptance Model (TAM) or the Unified Theory of Acceptance and Use of Technology (UTAUT), had been conducted to understand the human nature in association with the adoption or rejection of technologies that have bombarded the users. The coming of smart technologies (i.e., smart phones and devices), however, seems to have fundamentally changed the environment for adoption. The ubiquity combined with mobility of technology, especially when it comes to mobile apps, seem to make the old PC era of two-stage-pre and post-adoption models obsolete. A new model of adoption that identifies the determinants of technology acceptance and continuance is needed for the smart age. To this end, this paper undertakes an empirical study, by analyzing 229 users of Social Networking Service (SNS) mobile apps, to identify the role of user experience on the multi-stage adoption of technology, and provides results that User Experience (UX) plays the crucial role of bridging the separate stages of pre and post adoption of technologies. The paper concludes by providing practical implications of the new model as it relates to mobile apps and technologies, and recommendations for further studies to get a better understanding of technology adoption in the smart age.

소아 신이식의 최신 지견 (Current status of pediatric kidney transplantation)

  • 김성도;조병수
    • Clinical and Experimental Pediatrics
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    • 제52권10호
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    • pp.1075-1081
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    • 2009
  • Renal transplantation is the treatment of choice for children with end-stage renal disease. The outcome of pediatric kidney transplantation has improved dramatically in recent years, with lower acute rejection rates, superior graft survival, and low mortality. These improvements have allowed increased attention to other aspects of care for long-term survivors. Taking this into consideration, this review article will focus on the key issues related to pediatric kidney transplantation such as growth, neurocognitive function, nonadherence, and posttransplantation infectious complications, including lymphoproliferative disease, to broaden the understanding of pediatricians who provide pre-and postoperative care to children with end-stage renal disease.

Condition Monitoring of Check Valve Using Neural Network

  • Lee, Seung-Youn;Jeon, Jeong-Seob;Lyou, Joon
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2005년도 ICCAS
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    • pp.2198-2202
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    • 2005
  • In this paper we have presented a condition monitoring method of check valve using neural network. The acoustic emission sensor was used to acquire the condition signals of check valve in direct vessel injection (DVI) test loop. The acquired sensor signal pass through a signal conditioning which are consisted of steps; rejection of background noise, amplification, analogue to digital conversion, extract of feature points. The extracted feature points which represent the condition of check valve was utilized input values of fault diagnosis algorithms using pre-learned neural network. The fault diagnosis algorithm proceeds fault detection, fault isolation and fault identification within limited ranges. The developed algorithm enables timely diagnosis of failure of check valve’s degradation and service aging so that maintenance and replacement could be preformed prior to loss of the safety function. The overall process has been experimented and the results are given to show its effectiveness.

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32채널 뇌파 및 뇌유전발전위 Mapping 시스템 (32-Channel EEG and Evoked Potential Mapping System)

  • 안창범;박대준
    • 대한의용생체공학회:의공학회지
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    • 제17권2호
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    • pp.179-188
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    • 1996
  • A clinically oriented 32-channel electroencephalogram (EEG) and evoked potential (EP) mapping system has been developed EEG and EP signals acquired from 32-channel electrodes attached on the heroid surface are amplified by a pre-amplifier which is separated from main amplifier and is located near the patient to reduce signal attenuation and noise contamination between electrodes and the amplifier. The amplified signals are further amplified by a main amplifier where various filtering and gain contr61 are achieved An automatic artifact rejection scheme is employed using neural network-based EEG and artifact classifier, by which examination time is substantially reduce4 The continuously measured EEG sigrlals are used for spectral mapping, and auditory and visual evoked potentials measured in synchronous to the auditory and visual stimuli are used for temporal evoked potential mapping. A user-friendly graphical interface based on the Microsoft Window 3.1 is developed for the operation of the system. Statistical databases for comparisons of group and individual are included to support a statistically-based diagnosis.

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$\bar{x}$ 관리도의 표준관리한계와 부트스트랩 백분률 관리한계의 수행도 비교평가 (Comparison and Evaluation of Performance for Standard Control Limits and Bootstrap Percentile Control Limits in $\bar{x}$ Control Chart)

  • 송서일;이만웅
    • 산업경영시스템학회지
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    • 제22권52호
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    • pp.347-354
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    • 1999
  • Statistical Process Control(SPC) which uses control charts is widely used to inspect and improve manufacturing process as a effective method. A parametric method is the most common in statistical process control. Shewhart chart was made under the assumption that measurements are independent and normal distribution. In practice, this assumption is often excluded, for example, in case of (equation omitted) chart, when the subgroup sample is small or correlation, it happens that measured data have bias or rejection of the normality test. A bootstrap method can be used in such a situation, which is calculated by resampling procedure without pre-distribution assumption. In this study, applying bootstrap percentile method to (equation omitted) chart, it is compared and evaluated standard process control limit with bootstrap percentile control limit. Also, under the normal and non-normal distributions, where parameter is 0.5, using computer simulation, it is compared standard parametric with bootstrap method which is used to decide process control limits in process quality.

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Comparative performance evaluation of two UF pilot plants at the Alto da Boa Vista WTP (São Paulo, Brazil)

  • Oliveira, T.F.;Mierzwa, J.C.
    • Membrane and Water Treatment
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    • 제2권3호
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    • pp.175-185
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    • 2011
  • Ultrafiltration is an emerging technology for drinking water treatment because it produces better water quality as compared with conventional treatment systems. More recently, the combination of UF technology with other processes in order to improve its performance has been observed. These associations aim to maximize the contaminants removal and reduce membrane fouling. The operational performance of contaminants removal and water production of two UF pilot plants was compared. The first plant (Guarapiranga) was fed with raw water and the second plant (ABV) with pre-treated water by the coagulation, flocculation and sedimentation processes at Alto da Boa Vista WTP (Sao Paulo, Brazil). Both units operated continuously for approximately 2,500 hours, from September/2009 to January/2010. The results showed that the ABV UF pilot plant was able to operate at higher specific fluxes (6.2 $L.d^{-1}.m^{-2}.kPa^{-1}$ @ $25^{\circ}C$) than Guarapiranga (3.1 $L.d^{-1}.m^{-2}.kPa^{-1}$ @ $25^{\circ}C$). However, the number of chemical cleanings conducted in both pilot units during the considered operation period was the same (4 chemical cleanings for each plant), which shows that the pre-treatment reduced the membrane fouling. The water quality at ABV for all the variables analyzed was better, but the feed water quality was also better due to pretreatment. The rejection values for the different contaminants were higher at Guarapiranga mainly because of a pollution load reduction after pre-treatment at ABV. Even with the better performance of the ABV UF pilot plant, it is necessary to take into consideration the complexity of the complete treatment system, and also the costs involved in the construction and operation of a full-scale treatment unit.