• 동의생리병리학회지
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• 제16권2호
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• pp.311-315
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• 2002

Cellular death by apoptosis is an active process, depending on gene transcription and protein synthesis. It was reported that nitric oxide can induce apoptosis in several cancer cell-lines. We studied effects of Phytolacca esculentum van Houtt (Phytolaccaceae) Radix water extract (PRE) on the proliferation of transplanted-L1210 cells in mice. When PRE (500 mg/kg) was administered orally once a day for 7 days after transplantation of L1210 cells to mice, DNA fragmentation of transplanted-L1210 cells was induced and mitochondrial transmembrane potential of those cells was reduced. Additionally, DNA fragmentation of L1210 cells was induced by the treatment of PRE in vitro. Also, DNA fragmentation of L1210 cells was enhanced by co-culture with the peritoneal macrophages obtained from PRE-administered mice and was partly inhibited by L-NMMA in vitro. PRE enhanced the production of nitric oxide and tumor necrosis factor-α from peritoneal rnacrophages. These results suggest that PRE induces apoptosis of transplanted-L1210 cells via directive action on L1210 cells and stimulation of nitric oxide and tumor neaosis factor-α from macrophages.

• Asian-Australasian Journal of Animal Sciences
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• 제33권10호
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• pp.1642-1655
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• 2020

Objective: The aim of this study is to characterize the impact of additional electrical stimulation (AES) and various pre-rigor holding temperatures (for 3 h) on the ageing-potential of hot boned bovine M. longissimus lumborum (LL). Methods: Paired LL loins from 12 bulls were hot-boned within 40 min of slaughter, immediate AES applied and subjected to various holding temperatures (5℃, 15℃, 25℃, and 35℃) for 3 h. Results: AES did not accelerate the rate of rigor attainment, but the 3 h pre-rigor holding temperature did. Shear force values decreased as the pre-rigor holding temperatures increased. AES and holding for 3 h (at 25℃) resulted in higher water-holding capacity. Conclusion: Data confirmed that AES did not influence the various meat quality parameters in the present study, but pre-rigor holding temperature (25℃) alone or in combination with AES resulted in superior meat quality.

• International Journal of Precision Engineering and Manufacturing
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• 제3권4호
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• pp.24-30
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• 2002

In grinding operations, one of the most important problems is to increase efficiency of process. In order to achieve this purpose, it is necessary to administer the tool lift of grinding wheel and to optimize grinding conditions. Frequently dressing result in lowering the process efficiency remarkably and makes production cost high. On the other hand, grinding with a worn wheel causes the workpiece surface roughness to increase and often results in the occurrence of such troubles as chatter vibration and homing.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2003년도 5월 학술대회지
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• pp.97-100
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• 2003

The present study was planned to investigate the cortical activation correlated with producing morphologically complex Korean verbs by using. fMRI technique. In this study two derivational affixes and two inflectional affixes were selected: pre-final ending and final ending for inflectional affix and passive affix and causative affix for derivational affix. Two Experiment were conducted. The results of two Experiments suggest a possibility that process of pre-final ending is different from final ending.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 추계학술대회
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• pp.603-606
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• 2015

The post-production of smart farming defines the stage that the final products are delivered from producer to consumers via market on ICT network. It deals with the process of product packaging and distribution from producer to consumer with marketing strategy. This focus on reference model for post-production service including specialization, centralization of product delivery, and just-in-time delivery, and marketing system on the network. It defines a significant function component on post-production stage. The producer plays a significant role in economy being one of the main contributors to the many customers. This articles suggest the effective product distribution service which requires delivering the right product, in the right quantity, in the right condition, to the right place, at the right time, for the right cost, and encompassing global marketing based on ICT network, will be provided[1].

• Environmental Engineering Research
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• 제24권4호
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• pp.559-565
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• 2019

In order to alleviate the environmental pressure caused by production process of thermal power plants, the application of cleaner production is imperative. To estimate the implementation effects of cleaner production in thermal plants and optimize the strategy duly, it is of great significance to take a comprehensive evaluation for sustainable development. In this paper, a hybrid model that integrated the analytic hierarchy process (AHP) with least squares support vector machine (LSSVM) algorithm optimized by grid search (GS) algorithm is proposed. Based on the establishment of the evaluation index system, AHP is employed to pre-process the data and GS is introduced to optimize the parameters in LSSVM, which can avoid the randomness and inaccuracy of parameters' setting. The results demonstrate that the combined model is able to be employed in the comprehensive evaluation of the cleaner production in the thermal power plants.

• Environmental Engineering Research
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• 제22권2호
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• pp.193-202
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• 2017

The study estimated the relationship between carbon dioxide, crop and livestock production index in Ghana: Estimating the long-run elasticities and variance decomposition by employing a time series data spanning from 1960-2013 using both fit regression and ARDL models. There was evidence of a long-run equilibrium relationship between carbon dioxide emissions, crop production index and livestock production index. Evidence from the study shows that a 1% increase in crop production index will increase carbon dioxide emissions by 0.52%, while a 1% increase in livestock production index will increase carbon dioxide emissions by 0.81% in the long-run. There was evidence of a bidirectional causality between a crop production index and carbon dioxide emissions and a unidirectional causality exists from livestock production index to carbon dioxide emissions. Evidence from the variance decomposition shows that 37% of future fluctuations in carbon dioxide emissions are due to shocks in the crop production index while 18% of future fluctuations in carbon dioxide emissions are due to shocks in the livestock production index. Efforts towards reducing pre-production, production, transportation, processing and post-harvest losses are essential to reducing food wastage which affects Ghana's carbon footprint.

• 한국군사과학기술학회지
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• 제11권6호
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• pp.127-134
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• 2008

An autonomous reconnaissance ground robot performs its duty in various different environments such as mountain-scape, desert and under-water through changing its shape and form according to the environment it is working in. Making a prototype robot for each environment requires extra cost and time. It is also difficult to modify the problem after production. In this paper, we propose the adoption of M&S(Modeling & Simulation) environment for the production and design of the autonomous reconnaissance ground robot. The proposed method on the M&S environment contributed to the more effective and less time consuming production of the robot through the Pre-Modeling and Pre-Simulation process. For example, we showed the design and implementation of the autonomous reconnaissance ground robot under the proposed environment and tools.

• 만화애니메이션 연구
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• 통권35호
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• pp.67-88
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• 2014

국제적으로 한국의 장편 애니메이션은 수익과 관련된 흥행 실적을 나타내지는 못하고 있다. 전 세계적으로 흥행이 된다는 것은 엔터테인먼트와 관련이 있는데, 이러한 즐거움을 주는 요소로 웃음을 빼놓을 수 없다. 이러한 유머가 한국 애니메이션의 세계화에 중요한 역할을 하게 될 것임에도 불구하고, 아직 한국과 미국 애니메이션에 나타난 유머의 분석과 그 원인을 분석하는 연구는 많이 부족하다. 몇몇 해외 시장을 노리는 한국 애니메이션은 시나리오나 스토리보드 제작의 프리 프로덕션을 미국인이 맡는 경우들이 많이 생기고 있다. 이 논문에서는 한미 장편 애니메이션에 나타난 유머의 표현법의 차이를 빈도분석, 내용분석, 인터뷰를 통해서 연구하고 여기서 가장 많은 차이를 보인 스토리와 관련된 유머를 세분화하여 살펴보았다. 또한 한국 애니메이션에서 이러한 스토리와 관련된 유머를 보강하기 위한 방안을 마련해 보고자 하였다.

• 대한한의학방제학회지
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• 제28권2호
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• pp.147-155
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• 2020

PURPOSE : Andrographis Herba is used as a traditional herbal medicine in the Asian countries for the treatment common cold, fever, diabetes, hypertension, hepatitis, skin infections, snake bite, and other diseases. In this study, we investigated the anti-inflammatory effect of MeOH extract of Andrographis Herba (AHME) on LPS-activated Raw 264.7 cells. METHODS : Cell viability was determined by MTT assay. Nitric oxide (NO) production was determined by Griess reagent. Pro-inflammatory cytokines were detected by enzyme-linked immunosorbent assay. Expression levels of pro-inflammatory proteins were determined by Western blot analysis. RESULTS : Production of NO in LPS activated Raw 264.7 cells, was significantly decreased by pre-treatment with 3-30 ㎍/mL of AHME. Production of pro-inflammatory mediators such as TNF-α and IL were significantly decreased by AHME 30 ㎍/mL pre-treatment. AHME significantly decreased p-IκB and NF-κB expression. CONCLUSION : The results of this study indicate that AHME could inhibit the acute inflammatory response, via modulation of NF-κB activation.