• The Korean Journal of Physiology and Pharmacology
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• 제24권1호
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• pp.89-99
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• 2020

Although microscopic analysis of tissue slides has been the basis for disease diagnosis for decades, intra- and inter-observer variabilities remain issues to be resolved. The recent introduction of digital scanners has allowed for using deep learning in the analysis of tissue images because many whole slide images (WSIs) are accessible to researchers. In the present study, we investigated the possibility of a deep learning-based, fully automated, computer-aided diagnosis system with WSIs from a stomach adenocarcinoma dataset. Three different convolutional neural network architectures were tested to determine the better architecture for tissue classifier. Each network was trained to classify small tissue patches into normal or tumor. Based on the patch-level classification, tumor probability heatmaps can be overlaid on tissue images. We observed three different tissue patterns, including clear normal, clear tumor and ambiguous cases. We suggest that longer inspection time can be assigned to ambiguous cases compared to clear normal cases, increasing the accuracy and efficiency of histopathologic diagnosis by pre-evaluating the status of the WSIs. When the classifier was tested with completely different WSI dataset, the performance was not optimal because of the different tissue preparation quality. By including a small amount of data from the new dataset for training, the performance for the new dataset was much enhanced. These results indicated that WSI dataset should include tissues prepared from many different preparation conditions to construct a generalized tissue classifier. Thus, multi-national/multi-center dataset should be built for the application of deep learning in the real world medical practice.

• 자원리싸이클링
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• 제10권1호
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• pp.56-65
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• 2001

원전 안전주입계통 역지밸브의 유지보수 작업과 관련하여 작업자 방사성 피폭저감과 고가 부품의 재사용을 위해 방사능으로 오염된 이들 밸브를 화학제염법으로 제염을 수행하였다. 화학제염 후 역지밸브 내부 틈새에 잔류한 미세 고형입자를 제거하기 위해 초음파세척을 병행하였다. 역지밸브 disk arm holder를 사용한 사전 시험결과를 토대로 제염공정과 제염시약량을 결정하였으며 제염에 의한 부식산화물 용해거동, 방사능 제거거동과 재료부식거동을 조사하였다. 화학제염에 이은 초음파 적용결과, 초기 방사능의 93-95%가 제거되었으며 역지밸브 구성재질인 Type 304 stainless steel, Inconel-600 및 Stellite-6 에 대한 일반부식량은 각각 $ 2.1$\times10^{-2}$ , $6.0\times10^{-2}$ 및 1.7 mil 로써 일반부식 허용한계치의 3.3%, 24.0 % 및 2.7% 수준을 나타내어 제염효과와 재질건전성 면에서 효과적이었다.

• 전기학회논문지
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• 제62권9호
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• pp.1297-1301
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• 2013

This paper analyzes of PD occurrence position through an analysis of the arrival time difference between the GIS partial discharge signal. Because of GIS (Gas Insulated Switchgear) is a facility very important power equipment and as part of the equipment that make up the power system, the stabilization of the power industry, which accounted for 88.5% share of GIS substation in the form of a substation is an important equipment for power supply. In the situation where we are gradually expanding the need for preventive diagnosis in order to improve the efficiency of equipment management and failure prevention for Preventive diagnosis. In this paper as a method for extracting pre-defect of failure of GIS Apply the average value method of calculating the 5 times each using a pulse of the first time of the second pulse (${\Delta}t$) with an oscilloscope generation position PD(Partial Discharge). the results of GIS internal inspection, the partial discharge of the actual the position of the partial discharge was confirmed with an accuracy of about 82% of positions. Arrival time difference in the most effective manner if the partial discharge of GIS internal occurs by applying the averaging method and TOA(Time of arrival) method, the partial discharge occurs you through the measurement and analysis of PD signal occurs was confirmed in the experiment are presented and diagnostic methods location tracking.

• 한국압력기기공학회 논문집
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• 제12권1호
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• pp.62-69
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• 2016

Current guidance considers that uniaxially loaded specimen with a deep crack is used for the determination of the ductile-to-brittle transition temperature. However, reactor pressure vessel is under biaxial loading in real and the existence of deep crack is not probable through periodic in-service-inspection. The elastic stress intensity factor and the elastic-plastic J-integral which were used for crack-tip stress field and fracture mechanics assessment parameters. The difference of the loading condition and crack geometry can significantly influence on these parameters. Thus, a constraint effect caused by differences between standard specimens and a real structure can over/underestimate the fracture toughness, and it affects the results of the structural integrity assessment, consequentially. The present paper investigates the constraint effects by evaluating the master curve $T_0$ reference temperature of PCVN (Pre-cracked Charpy V-Notch) and small scale cruciform specimens which was designed to simulate biaxial loading condition with shallow crack through the fracture toughness tests and 3-dimensional elastic-plastic finite element analyses. Based on the finite element analysis results, the fracture toughness values of a small scale cruciform specimen were estimated, and the geometry-dependent factors of the cruciform specimen considered in the present study were determined. Finally, the transferability of the test results of these specimens was discussed.

• 한국철도학회논문집
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• 제12권1호
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• pp.55-64
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• 2009

콘크리트궤도는 유지보수상의 장점으로 인하여 자갈궤도를 급속히 대체하고 있다. 반면에 보수보강이 어렵기 때문에 매우 엄격한 설계와 시공기술이 필요하며 이러한 기술을 만족하기 위해서는 평가기술 또한 뒷받침이 되어야 한다. 본 논문에서는 이와 같이 시공 및 유지보수의 핀 평가기술을 확보하기 위한 방안으로서 탄성파를 이용하는 비파괴조사기법을 다양하게 적용하였다. 사용된 기법은 SASW시험, 임팩트에코시험, 연속임팩트에코시험이다. 시험은 49개의 프리캐스트 판넬의 강성구조와 충진성능을 평가하는 목적으로 총 5,353회에 걸쳐 수행되었다. 적용 결과, 콘크리트재료 자체의 비균질성으로 인하여 탄성파시험의 적용 및 분석이 제한적이지만 본 논문에서 목적하는 슬래브의 강성구조과 충전성(공극)에 대한 신뢰성 있는 조사 결과를 얻을 수 있을 것으로 나타났다.

• 한국학교보건학회지
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• 제16권1호
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• pp.37-54
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• 2003

Recent domestic findings indicate steep increase of geriatric diseases such as obesity, diabetes, and high blood pressure among children and adolescents. It is, therefore, necessary to establish a new system for constitution inspection that reflects domestic adolescents' health conditions by the introduction of feasible items and systematic methods in the inspect ion. The objective of this study is to grasp the problems and to present proper ways of improving the system. As the method of the research during the period from September 2001 to March 2002 we refer to the domestic and foreign literature, and ask the advice of the specialists in pediatrics, family medicine, endocrine, cardiology. As on-site research we us e survey of nationwide elementary, middle, and high schools, visit representative local schools and have an interview with school nurses. Through the interview we try to find practical problems of school heath care and find proper method of students physic al examination. The abstract of the problems of student examination system is as following. To the question about the extent of the result of physical examination 46. 46.4%(school doctor) and 42.6%(parents and students) of the respondents answered "don't know". It means neglectfulness about examination itself. 62% of the school nurses responded "unsatisfactory" people who take charge of practical affairs have complaint about pre sent examination method. Because of the short time of the examination, and numerous students, the examination was incomplete. Several questions, method of physical examination, content of physical examination and list of physical examination, were raised. Reform measures for physical examination system of students were presented by physician, school nurses, students and parents of student.

• 간호행정학회지
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• 제8권2호
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• pp.295-308
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• 2002

Purpose: The purpose of this quasi-experimental research is to develop the CP for primary THR patients and verify its effectiveness. Method: The CP is designed for both patients and medical employees to meet the 14-day-long hospitalization with an expert and clinical validity test, and the standardized orders are also created. 21 eligible subjects for the control group(with common care plan) and 27 subjects for the experimental group(with CP service) were assigned. Data were collected from questionnaires to evaluate patients' satisfaction level of nursing care and CP, investigation of physical complications, inspection of LOS(length of hospital stay) and hospital charges from April 2000 to February 2001 at K-hospital in Daegu. The collected data were analyzed by using the SAS program. Results: After implementation of CP, there was a statistically significant reduction in mean length of stay. The hospital charges have no considerable difference between two groups. Frequency of physical complications is reduced considerably. The experimental group scored much higher than the control group on the satisfaction level toward nursing care. And in the analysis of CP satisfaction questionnaires, many subjects have high satisfaction in items of 'I see the treatment process and hospital life', 'I feel that I am participating in my treatment process with health care staff'. The analysis of variances which cause a prolonged LOS supports that it's necessary to strengthen an evaluation of pre-operative outpatients' condition and link the home nursing care system in discharge for more shortening of LOS. Conclusion: The above results show that CP can have a positive impact on satisfaction level of inpatients with primary THR and the hospital.

• Corrosion Science and Technology
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• 제14권1호
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• pp.12-18
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• 2015

Since the operation period of nuclear power plants has increased, the degradation of buried pipes gradually increases and recently it seems to be one of the emerging issues. Maintenance on buried pipes needs high quality of management system because outer surface of buried pipe contacts the various soils but inner surface reacts with various electrolytes of fluid. In the USA, USNRC and EPRI have tried to manage the degradation of buried pipes. However, there is little knowledge about the inspection procedure, test and manage program in the domestic nuclear power plants. This paper focuses on the development and build-up of real-time monitoring and control system of buried pipes. Pipes to be tested are tape-coated carbon steel pipe for primary component cooling water system, asphalt-coated cast iron pipe for fire protection system, and pre-stressed concrete cylinder pipe for sea water cooling system. A control system for cathodic protection was installed on each test pipe which has been monitored and controlled. For the calculation of protection range and optimization, computer simulation was performed using COMSOL Multiphysics (Altsoft co.).

• 컴퓨터교육학회논문지
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• 제23권2호
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• pp.31-39
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• 2020

소프트웨어교육의 중요성이 강조되면서, 초등학생의 컴퓨팅사고력 향상을 위한 다양한 교육이 이루어지고 있다. 하지만 선행연구들을 살펴보면 특정 환경이나 학습자만을 고려한 경우가 많아 학교현장에 적용하는 것에 한계가 있다. 따라서 본 연구에서는 교과서의 내용을 바탕으로 학습자에게 영향을 미칠 수 있는 요인인 교구와 컴퓨팅 사고력에 대한 학습자 수준이라는 특성을 고려한 교수·학습활동을 구성하여 소프트웨어교육을 실시하고, 학습자들의 컴퓨팅사고력 향상도 비교를 통해 효과적인 소프트웨어교육 방법의 방향을 제안하였다. 연구결과 교구와 학습자 수준에 따라서 컴퓨팅사고력 향상에 차이가 있는 것으로 나타났는데 구체적으로 활용 교구에 있어서는 비주얼 프로그래밍과 언플러그드 방식을 활용한 교수·학습활동이 보다 효과적이었으며 학습자 수준에 따라서는 사전검사에서 컴퓨팅사고력의 수준이 낮은 것으로 평가된 학생들이 상대적으로 높은 향상도를 보였다. 이러한 경향은 초등학교 소프트웨어교육에서 교수·학습활동을 구성함에 있어 다양한 학습요인을 고려할 필요성이 요구된다고 보인다.

• Geomechanics and Engineering
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• 제15권4호
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• pp.927-935
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• 2018

The mechanical behavior of the brittle material samples containing the internal and edge cracks are studied under direct shear tests. It is tried to investigate the effects of stress interactions and stress intensity factors at the tips of the pre-existing cracks on the failure mechanism of the bridge areas within these cracks. The direct shear tests are carried out on more than 30 various modeled samples each containing the internal cracks (S models) and edge cracks (E models). The visual inspection and a low power microscope are used to monitor the failure mechanisms of the tested samples. The cracks initiation, propagation and coalescences are being visualized in each test and the detected failure surfaces are used to study and measure the characteristics of each surface. These investigations show that as the ratio of the crack area to the total shear surface increases the shear failure mode changes to that of the tensile. When the bridge areas are fixed, the bridge areas in between the edge cracks have less strength than those of internal cracks. However, the results of this study show that for the case of internal cracks as the bridge area is increased, the strength of the material within the bridge area is decreased. It has been shown that the failure mechanism and fracture pattern of the samples depend on the bridge areas because as the bridge area decreases the interactions between the crack tip stress fields increases.