• Title/Summary/Keyword: Potency

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Immune Responses in Swine and Experimental Animals Given Inactivated Aujeszky’s Disease Virus Antigens (불활화 Aujeszky’s disease virus 항원의 자돈과 실험동물에서의 면역반응)

  • 박정우;이종인;최윤식
    • Korean Journal of Veterinary Service
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    • v.13 no.1
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    • pp.54-63
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    • 1990
  • We have studied about the safety, immunity and protective potency in swine and experimental am mais of two inactivated vaccine produced with NYJ-1-87 strain of ADV that was isolated in Korea. Result obtained through the experiments were summarized as follows. 1. The safe potency of ADV antigens inactivated with BEI and formaline to mouse & guinea pig was on the whole good, but protective potency rates of those to challenge with ADV were 60-75% without the differences to two antigens. 2. Safety, immunity & protective potency of ADV antigens inactivated with BEI and formaline to swine were on the whole excellent, except for a mild increase of rectal temperature in some pigs after challenge with ADV. 3. When virus excretion of the experimental groups after challenge with ADV was examed by swabbing of nasal, all pigs of control gorup excreted virus from 2 days p.c., partially to 10 days p.c.. But in vaccinated groups, only 25-50% of all pigs of each group excreted virus during experimental periods. 4. Titers of antibodies in swine & quinea pig vaccinated with inactivated ADV antigens become increased after the 1 weeth p.i. showing the highest liters on the 4-5 weeths p.i.

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The Image Evaluation and Preference of the Campus Wear of College Males and Females (남녀 대학생의 캠퍼스웨어 이미지 평가와 선호도에 관한 연구)

  • Hwang Mi-Sun;Lee Myoung-Hee
    • Journal of the Korean Society of Costume
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    • v.55 no.1 s.91
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    • pp.139-150
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    • 2005
  • The purpose of this study was to find out differences of image evaluation according to perceiver's gender and clothing style, and to investigate the clothing preference according to the style of campus wear. Subjects were 340 college males and females in Seoul. The image of campus wear was divided into four dimensions: neatness, polishing, potency, and activity. Gender had significant influences on the perception of neatness, polishing, and potency. Males perceived the campus wear to be neater, more polished and potent than females. There were significant differences in evaluating neatness, polishing, potency, and activity according to campus wear style. The sweatshirt was estimated low in polishing and potency but high in activity. The T-shirt${\cdot}$short pants was estimated low in polishing and neatness but high in activity. The jumper was rated high in activity, and pants suit high in neatness, polishing, and potency, but it was estimated low in activity. The skirt suit was rated high in neatness and low in activity. The knit cardigan was perceived as polished image. College students preferred knit cardigan, one-piece dress, jumper, and pants suit, however, T-shirt${\cdot}$short pants was comparatively less preferred. Males estimated the knit cardigan to be more favorable than females. Characteristics of clothing image which influenced on preference of campus wear were different between males and females.

The Impression of on Korean Catholic Priest's Ritual Dress (가톨릭 사제복식에 대한 인상형성 연구)

  • 김광영;조정미;남미우
    • Journal of the Korean Society of Clothing and Textiles
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    • v.23 no.5
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    • pp.703-714
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    • 1999
  • The purpose of the present study was to identify the effect of ritual dress on korean catholic priest's impression. The subject consisted of 415 undergraduated students. The experimental materials developed for this study were 3 type color photographs stimuli of catholic priest model and 7-point sementic differential scale composed of 49 bipolar adjectives representing personal traits. The data were analyzed by factor analysis. the major findings drawn from this study were as follows : Four factors emerged to account for the dimentional structure of the impression of each dress style. Four factors were titled as open-hearted mind symbolic meaning nature of priest potency. The open-hearted mind factor was the largest throughout the 3types ritual dress. Casula had a positive effect on open-hearted mind nature of prist and negative on symbolic meaning potency. Sutan had a positive effect on open-hearted mind potency nature of priest and negative on symbolic meaning. Black suit with roman collar had a positive effect on open-hearted mind symbolic meaning nature of prist and negative on potency, Therefore the ritual dress had significant effect on korean catholic priest' impressin of open-hearted mind symbolic meaning nature of prist activity and potency

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An Electromyographic Study on the Edentulous Patients (E.M.G를 이용한 무치악에서의 저작근에 대한 연구)

  • 이승우
    • Journal of Oral Medicine and Pain
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    • v.2 no.1
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    • pp.8-16
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    • 1974
  • The author performed electromyographic analysis on edentulous patients aging 52 to 77 who have upper and lower full dentures for 3 to 7 years of duration. And the graphs were recorded in physiologic rest position, incisal occlusion, molar occlusion, left lateral excursion, right lateral excursion and mandibular projection. The results obtained are as follows : 1. 80 per cent of the patients are in unilateral mastication. 2. The shorter history of edentulous mouth reveals the more electric potency. 3. Facial deviation owing to unilateral mastication is the cause of higher electric potency to the deviated site. 4. There were no difference in electric potency between mandibular projection and incisal occlusion.

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Potency of Several Structurally Different Acetylcholinesterase Reactivators to Reactivate House Fly and Bovine Acetylcholinesterases Inhibited by Paraoxon and DFP

  • Park, No-Jung;Jung, Young-Sik;Musilek, Kamil;Jun, Daniel;Kuca, Kamil
    • Bulletin of the Korean Chemical Society
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    • v.27 no.9
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    • pp.1401-1404
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    • 2006
  • Eight structurally different acetylcholinesterase reactivators derived from currently commercially available oximes were tested for their potency to reactivate acetylcholinesterase inhibited by pesticide paraoxon (P) and DFP (D). Housefly AChE (F) and bovine red blood cell AChE (B) were used as the source of the cholinesterases. Ellman's method was taken to examine cholinesterases activity. The results show that four AChE reactivators are potent AChE reactivators, able to reach reactivation potency of more than 30% in all cases - PF, PB, DF and DB. Their reactivation potency was comparable with that of pralidoxime and even higher compared with that of HI-6, standard AChE reactivators currently available on the market.

Comparison of Eye Irritation Potency with Skin Irritation and Cytotoxicity Potency of Anti-wrinkle Agents (주름방지용 화장품원료의 안점막 자극성과 피부자극성 및 세포독성과의 비교)

  • 이은희;이종권;김주환;정경미;정해관;이선희;정수연;홍진태
    • Toxicological Research
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    • v.17 no.2
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    • pp.143-149
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    • 2001
  • In the present study, we examined eye irritation oj six anti-wrinkle agents (ascorbic acid, glycolic acid, all trans-retinoic acid, ginseng extract, retinol, EB). We also compared eye irritation with skin irritation and cytotoxicity in HaCaT cells by these agents. The highest eye irritation was found in glycolic acid, but all trans-retinoic acid showed the highest skin irritation. The rank of eye irritation was not correlated with the cytotoxicity of agents. This result shows that eye irritation potency by these agents were not correlated with skin irritation potency, and cytotoxicity in HaCaT cells.

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황련의 증량에 따른 전탕액이 Pseudomonas aeruginosa에 미치는 항균효과에 대한 실험적 연구

  • Seo, Hyeong-Sik
    • Journal of Pharmacopuncture
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    • v.10 no.1 s.22
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    • pp.17-21
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    • 2007
  • Objective : This experimental study was performed to investigate the effect of Coptidis rhizoma extract compared with quantity on Pseudomonas aeruginosa that induce keratitis. Methods : MIC was measured by dropping to 50 ${\mu}l$ according to density Coptidis rhizoma extract(100%, 10%, 1%, 0.1%) compared with quantity(40g, 80g, 120g, 160g). Anti-bacterial potency was measured by the size of inhibition zone with change of volume. Results : MIC on Pseudomonas aeruginosa in Coptidis rhizoma extract compared with quantity(40g, 80g, 120g, 160g) was not showed all samples(100%, 10%, 1%, 0.1%). Conclusions : Coptidis rhizoma extract compared with quantity was not showed anti-bacterial potency on Pseudomonas aeruginosa. The results differ that Coptidis rhizoma extract was showed anti-bacterial potency in 1999 year. Anti-bacterial Potency of Coptidis rhizoma extract compared with quantity on Pseudomonas aeruginosa must be studied.

The Experimental Study on Anti-bacterial Potency of Soyum Herbal-acupuncture, Hwangryunhaedoktang & Coptidis rhizoma on Staphylococcus epidermidis (소염 약침액, 황련해독탕, 황련이 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구)

  • Seo, Hyung-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.19 no.2
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    • pp.19-25
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    • 2006
  • Objective : This experimental study was performed to investigate the effect of Soyum Herbal-acupuncture, Hwangryunhaedoktang & Coptidis rhizoma on Staphylococcus epidermidis that induce keratitis. Methods : MIC was measured by dropping to $50{\mu}l$ according to density Soyum Herbal-acupuncture, Hwangryunhaedoktang & Coptidis rhizoma(100%, 10%, 1%, 0.1%). Anti-bacterial potency was measured by the size of inhibition zone with change of volume. Results : 1. MIC on Staphylococcus epidermidis in Soyum Herbal-acupuncture dippear all sample. 2. MIC on Staphylococcus epidermidis in Hwangryunhaedoktang disappear all sample. 3. MIC on Staphylococcus epidermidis in Coptidis rhizoma was 100%, $50{\mu}l$ and anti-bacterial potency increase compare with quantity. Conclusions : The present author think that Soyum Herbal-acupuncture must be extracted a new method for anti-bacterial potency and Coptidis rhizoma was made Herbal-acupuncture for eye drops.

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The Experimental Study on Anti-bacterial Potency of Coptidis rhizoma extract on Staphylococcus aureus & Staphylococcus epidermidis (황련 전탕액이 Staphylococcus aureus와 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구)

  • Seo, Hyung-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.19 no.2
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    • pp.71-76
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    • 2006
  • Objective : This experimental study was performed to investigate the effect of Coptidis rhizoma extract on Staphylococcus aureus and Staphylococcus epidermidis that induce keratitis. Methods : MIC was measured by flowing to $50{\mu}l$ according to density Coptidis rhizoma extract(100%, 10%, 1%, 0.1%). Anti-bacterial potency was measured by the size of inhibition zone with change of volume. Results : 1. MIC on Staphylococcus aureus in Coptidis rhizoma extract was 100%, $50{\mu}l$ and anti-bacterial potency increase compare with quantity. 2. MIC on Staphylococcus epidermidis in Coptidis rhizoma extract was 100% & 10%, $50{\mu}l$ and anti-bacterial potency increase compare with quantity. Conclusions : The Present author think that Coptidis rhizoma extract must be made a new eye drops.

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Estimation of Relative Potency with the Parallel-Line Model

  • Lee, Tae-Won
    • The Korean Journal of Applied Statistics
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    • v.25 no.4
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    • pp.633-640
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    • 2012
  • Biological methods are described for the assay of certain substances and preparations whose potency cannot be adequately assured by chemical or physical analysis. The principle applied through these assays is of a comparison with a standard preparation to determine how much of the examined substance produces the same biological effects as a given quantity (the Unit) of the standard preparation. In these dilution assays, to estimate the relative potencies of the unknown preparations to the standard preparations, it is necessary to compare dose-response relationships of standard and unknown preparations. The dose-response relationship in the dilution assay is non-linear and sigmoid when a wide range of doses is applied. The parallel line model (applied to the dose region with the steepest slope) is used to estimate the relative potency. In this paper, the statistical theory in the parallel line model is explained with an application to a dilution assay data. The parallel line method is implemented in a SAS program and is available at the author's homepage(http://cafe.daum.net/go.analysis).