• Neonatal Medicine
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• v.18 no.1
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• pp.104-110
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• 2011

Purpose: The unique nutrient requirements of premature infants necessitate knowledge of the composition of human milk produced by mothers of such infants. We investigated longitudinal changes in iron concentration of preterm human milk and compared to those observed in human milk of mothers of 1-week old term infants to determine optimal iron supplementation guidelines when preterm infants are nourished exclusively by breast feeding. Methods: Human milk samples were collected at 1, 2, 4, 6, 8 and 12 weeks postpartum from 103 mothers who delivered infants of gestational age <34 weeks or weighing <1,800 g. Term human milk samples were collected at 1 week postpartum from 24 mothers. Results: There were no significant differences in the iron concentrations of preterm human milk obtained at 2 to 8 weeks postpartum (36.3${\pm}$23.1 to 45.8${\pm}$26.0 $\mu$g/dL), but these concentrations were higher than those noted at 1 week in preterm (23.1${\pm}$14.6 $\mu$g/ dL) and term (25.2${\pm}$7.55 $\mu$g/dL) infants. The iron concentration in preterm human milk obtained at corrected term age (42.2${\pm}$19.4 $\mu$g/dL) was significantly higher than that of mature term human milk (25.2${\pm}$7.55 $\mu$g/dL). Conclusion: The concentration of iron in preterm human milk was consistently low during the first 3 months of lactation. Supplementation with iron of at least 2 mg/kg/day should be considered for preterm infants who are exclusively breastfed and who have low body iron stores, to meet the minimum enteral iron requirements recommended by AAP-CON (2004).

• Journal of Veterinary Clinics
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• v.8 no.2
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• pp.157-170
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• 1991

Effects of recombinant bovine somatotropln(${\gamma}$BST) on hematologie and blood chemical values were investigated in twenty-five multiparous Holstein dairy cows. Recombinant BST was administered by two different routes ; intramusculary(12.5mg and 25mg/day) and subcutaneously(500mg and 750mg) in sustained-release vehicle every 2 weeks beginning 4 weeks postpartum and continuing for 7 months. Whole blood and serum samples were collected 0, 1, 2, 3, 5, and 7 months after beginning of treatments from control and ${\gamma}$BST-administered groups. Hematologic values including RBC, PCV, HB, MCH, MCHC, WBC and differential counts of treatment groups receiving ${\gamma}$BST were similiar to those of control group. Blood chemical values observed were total protein, albumin, A/G ratio, glucose, cholesterol, Ca, Pi, Ca/pi ratio, total bilirubin, creatinine, BUN, alkaline phosphatase, lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase. There were no significant differences in blood chemical values of cows administered with ${\gamma}$BST from those of control. Although some blood chemical values were fluctuated at a certain observation period, they were remained within the normal physiological ranges. It is concluded from the observations of these experiments that the dose and dosage froms of ${\gamma}$BST employed in this work might not affect hematologic and blood chemical values in dairy cows under the normal sanitary condition and adequate nutritional balance.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.57-66
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• 2010

Purpose: To provide basic informations for guidelines of Ginseng usage during lactation. Method: Based on a regulation of scope and preparation of herbal prescriptions by Ministry of health and welfare of Korea, we selected the formulae for postpartum care and disease in 7 Korean Medical Classics. And we searched the number of formulae including Ginseng, dosage and indications of Ginseng in formulae in those books. Results: The range of Ginseng dosage during lactation from medical classics is 1.5-18.75g/day for medical purposes. Indications of Ginseng are lethargy, excessive bleeding, asthma, fever, cold, pain, dizziness, mental disorder, spasm, digestive problem, constipation, diarrhea, urinary incontinence, edema, breast engorgement, lack of breastmilk, breast ulcer, etc. But Ginseng had not been used in the case of stroke, epistaxis, beginning of mastitis, tumor of lower abdomen. Conclusions: Ginseng should be recommended less than 1.5g/d as a nutritional supplement. If breastfeeding woman wants to take Ginseng as a medication or as a tonic, she should consult with a official specialist about proper prescription and dosage instead of risky random medication.

• Journal of Korean Academy of Nursing
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• v.14 no.1
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• pp.50-59
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• 1984

The purpose of this study was to evaluate the maternal perception of her newborn and identify the risk of mother-infant relationship. Broussard's Neonatal Perception Inventories were completed by 113 mothers on the first or second postpartum day (Time I ) while they were still in the University Hospital. These inventories were again administered when the infants were approximately one month of age (Time Ⅱ). The data was analyzed by S.P.S.S. program and the results were as follows: 1) There were differences between the mothers' exportations of the average baby and perceptions of their babies at Time I and Time Ⅱ (p<0.01). 2) The maternal perception of her newborn at Time I was not related with the education, the parity, the experience of abortion, the type of delivery and the sex of baby but related with the method of feeding (p<0.05). 3) The maternal perception of her newborn at Time Ⅱ was not related with the education, the parity, the experience of abortion, the type of delivery and the method of feeding but related with the sex of baby (p<0.05). 4) The changes of maternal perception between Time I and Time Ⅱ were not related with the education, the parity, the experience of abortion, the method of delivery and the sex of baby but related with the method of feeding (p<0.1). 5) The maternal perception of the newborn was not correlated with the age and the duration of labor.

• Child Health Nursing Research
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• v.11 no.3
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• pp.340-347
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• 2005

Purpose: This study was done to develop a new nursing intervention, Meridian Massage, and to investigate its effect on weight in infants and mother-infant interaction. Method: This study was conducted using a quasi experimental non equivalent control group pretest-posttest design. Thirty-one newborn infants from a postpartum Management Center were selected and assigned to two groups, experimental and control. Data were collected from February 1 to September 30, 2004. Infants in the experimental group (16) were given Meridian massage for 15 minutes daily for 6 days and weighed every day at 10 am. Using the Nursing Child Assessment Feeding Scale(1978), mother-infant interaction was determined before the treatment, after 1 week and 1 month after the massage. Results: Infants in the experimental group had a higher average weight than those in the control group and the difference was significant (Z=-2.29, p=.022). For mother-infant interaction, the experimental group had higher scores tHan the control group, and the difference was significant between both the two groups, and the 3 measurement times. Conclusion: The Meridian Massage in this study showed positive weight gain and positive mother-infant interaction. This study shows that meridian massage is an effective nursing intervention in improving infant development.

• Korean Journal of Veterinary Research
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• v.31 no.4
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• pp.425-431
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• 1991

Effects of recombinant bovine somatotropin$({\gamma}BST)$ on mineral composition of milk were investigated in Twenty-five multiparous Holstein dairy cows. Recombinant BST was administered by two different routes; intramusculary(12.5mg and 25mg/day) and subcutaneously (500mg and 750mg) in sustained-release vehicle every 2 weeks beginning 4 week postpartum and continuing for 7 months. Milks were collected 0,1,2,3,5 and 7 months after beginning of treatments in control and ${\gamma}BST$-administered groups. Mineral composition, such as Ca, Pi, Na, K, Mg, Zn, Fe and Mn, in milk were not affected by the administration of ${\gamma}BST$ regardless of dose and dosage forms. It is concluded from the observations of these experiments that the dose and dosage forms of ${\gamma}BST$ employed in this work might not affect milk mineral composition in dairy cows under the normal sanitary condition and adequate nutrient balance.

• International Journal of Oral Biology
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• v.41 no.2
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• pp.63-68
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• 2016

The aim of this study was to investigate the effect of n-3 polyunsaturated fatty acids (PUFAs) on eruptive movement during tooth development. Sprague-Dawley (SD) rat pups were randomly divided into two groups; control group and experimental group. The experimental group was administered daily with n-3 PUFA by intraperitoneal (IP) injection. After 10 days postpartum, rat pups were sacrificed to evaluate the effect of n-3 PUFA on eruptive tooth movement. Histological analyses were by hematoxylin-eosin (H&E) staining. Tartrate-resistant acid phosphatase (TRAP) assay was performed to compare the osteoclast distribution in the bone matrix above the developing molar teeth. Incisor teeth eruptions were noticeably observed in IP group, as compared to control group. Rat pups in IP group showed faster tooth eruption on day 8 after birth. Through histological analyses, IP group showed thinner bone matrix and more osteoclasts above the $1^{st}$ molar teeth, as compared to control group. TRAP assay showed significantly stronger stained pattern that the osteoclast above the $1^{st}$ molar teeth in IP group, as compared to control group. The results suggested that n-3 PUFA could affect osteoclastic activity involved in bony remodeling during eruptive tooth movement.

• Women's Health Nursing
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• v.18 no.2
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• pp.98-107
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• 2012

Purpose: This study was done to identify the effects of self-breast pumping on breastfeeding rates and, the degree of breast milk fullness among primiparous women giving birth by cesarean section. Methods: The study design was a non-synchronized posttest control group experiment with repeated measures. The participants were 60 women, 31 in the experimental group who used a manual pump 5 times a day after exclusive breastfeeding and 29 in the control group who breastfed exclusively with no other interventions. Results: While self-breast pumping did not improve breastfeeding rates or the degree of breast milk fullness at any of the time points studied, breastfeeding rates continued to remain high till 12 weeks postpartum in both groups. Conclusion: Although some modifications in research methods will be required to identify the effects of breast pumping and exclusive breastfeeding, both these approaches can be used as interventions to improve breastfeeding rates and breast milk quantity.

• International Journal of Oral Biology
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• v.36 no.4
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• pp.167-172
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• 2011

LAR-RPTP (leukocyte common antigen-related receptor protein tyrosine phosphatase) is an important regulator in the nervous system, but little is known about its expression pattern in rat trigeminal ganglion (TG) neurons. To examine whether LAR-RPTP is expressed in the TG in the current study, we sacrificed rats at 0, 7, 10 and 56 day postpartum (dpp) and a second group of rats at 3 and 5 days after an experimental tooth extraction as a TG injury model. RT-PCR was then used to determine the level of LAR-RPTP expression in the TG and immunohistology was employed to detect the subcellular localization of the protein. The mRNA expression of LAR-RPTP during the developmental stages in the TG was found to gradually increase. After experimental tooth extraction however, these transcript levels had significantly decreased at three days. LAR-RPTP protein signals in the TG were found to be cytoplasmic in the normal animals but interestingly, at five days after an experimental tooth extraction, these signals were rare. These results indicate that LAR-RPTP may be regulated during both the developmental as well as regenerative processes that take place in the TG. This further suggests that LAR-RPTP is not only involved in primary axonogenesis but possibly also in the molecular control of axons during TG repair.

• Journal of Veterinary Clinics
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• v.12 no.1
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• pp.819-827
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• 1995

An attempt to reproduce pyometra by means of experimental uterine infection was conducted with the 10 mongrel hitches of the anestrus, proestrus, metestrus, and postpartum uterine involution stages. Organism used was hemoltic E. coli. origially isolated from uterine pus of a bitch that had the canine pyometra. One ml of broth culture containing $2{\times}10^6$ CFU was inoculated into the uterine horn with the uterine cervix ligated. Aか bitches were ovariohysterectomized at the 7th or 14th day after inoculation and the uterus was provided for macroscopic and microscopic observations. An experimental production of pyometra was successful in 7(70%) of 10 mongrel bitches, and the incidence of pyometra was seen 100% in the stage of anestrus, 100% in the stage of metestrus, 50.0% in the stage of pyomestrus, and 33.359 in the stage of uterine involution. Histologically, these uteri were characterized by the presence of cystic. endomeetrial hyperplasia(CEH) and acute endometritis superimposed on the cystic hyperplasia. And the pyometra with CEH could be seen 66.7% in metestrus 50% in anestrus, 33.3% in involution and in 0% in proestrus stage. Blood progesterone concentrations were showed as a normal range of the each stage of sexual cycle and any relationships between the progesterone concentrations and the incidence of pyometra were not observed.