• Title/Summary/Keyword: Postgraduate Research

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Late-term effects of hypofractionated chest wall and regional nodal radiotherapy with two-dimensional technique in patients with breast cancer

  • Yadav, Budhi Singh;Bansal, Anshuma;Kuttikat, Philip George;Das, Deepak;Gupta, Ankita;Dahiya, Divya
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.109-118
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    • 2020
  • Purpose: Hypofractionated radiotherapy (RT) is becoming a new standard in postoperative treatment of patients with early stage breast cancer after breast conservation surgery. However, data on hypofractionation in patients with advanced stage disease who undergo mastectomy followed by local and regional nodal irradiation (RNI) is lacking. In this retrospective study, we report late-term effects of 3 weeks post-mastectomy hypofractionated local and RNI with two-dimensional (2D) technique in patients with stage II and III breast cancer. Methods: Between January 1990 and December 2007, 1,770 women with breast cancer who were given radical treatment with mastectomy, systemic therapy and RT at least 10 years ago were included. RT dose was 35 Gy/15 fractions/3 weeks to chest wall by two tangential fields and 40 Gy in same fractions to supraclavicular fossa (SCF) and internal mammary nodes (IMNs). SCF and IMNs dose was prescribed at dmax and 3 cm depth, respectively. Chemotherapy and hormonal therapy was given in 64% and 74% patients, respectively. Late-term toxicities were assessed with the Radiation Therapy Oncology Group (RTOG) scores and LENT-SOMA scales (the Late Effects Normal Tissue Task Force-Subjective, Objective, Management, Analytic scales). Results: Mean age was 48 years (range, 19 to 75 years). Median follow-up was 12 years (range, 10 to 27 years). Moderate/marked arm/shoulder pain was reported by 254 (14.3%) patients. Moderate/marked shoulder stiffness was reported by 219 (12.3%) patients. Moderate/marked arm edema was seen in 131 (7.4%) patients. Brachial plexopathy was not seen in any patient. Rib fractures were noted in 6 (0.3%) patients. Late cardiac and lung toxicity was seen in 29 (1.6%) and 23 (1.3%) patients, respectively. Second malignancy developed in 105 (5.9%) patients. Conclusion: RNI with 40 Gy/15 fractions/3 weeks hypofractionation with 2D technique seems safe and comparable to historical data of conventional fractionation (ClinicalTrial.gov Registration No. NCT04175821).

Employee Performance Optimization Through Transformational Leadership, Procedural Justice, and Training: The Role of Self-Efficacy

  • KUSUMANINGRUM, G.;HARYONO, Siswoyo;HANDARI, Rr. Sri
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.12
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    • pp.995-1004
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    • 2020
  • This study aims to analyze the effect of transformational leadership (TL), procedural justice (PJ), and training (T) on employee performance (EP) mediated by self-efficacy (SE). The object of this research is Rumah Sakit Umum Daerah (RSUD) M.Th. Djaman, a hospital in Sanggau Regency, while the subjects are the institution's staff. Data collection search uses purposive sampling with a total of 120 samples. Data are obtained through questionnaires distributed directly to respondents using the Google Form application. Data analysis techniques used in this study include standard error of mean (SEM) with AMOS software version 24.00. Methods use to test validity and reliability of data include Confirmatory Factor Analysis (CFA), Construct Reliability (CR) and VE. The results of the analysis show that only training has a significant effect on self-efficacy, and self-efficacy has a significant effect on employee performance. Also, self-efficacy is proven to mediate the role of training on employee performance; the other hypotheses are not significant. Training is the most prominent positive factor affecting self-efficacy and self-efficacy has a significant effect on employee performance at RSUD M.Th. Djaman. The results of this study can be used as a reference by management in determining what policy priorities should take precedence.

Theoretical Basis of Studying the Educational Environment with the Application of GR-Technologies

  • Romanchenko, Inna;Vasylevska, Olena;Haltsova, Svitlana;Babicheva, Hanna;Batsula, Natalia;Kravchenko, Hanna;Lytvyn, Aelita
    • International Journal of Computer Science & Network Security
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    • v.21 no.4
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    • pp.28-32
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    • 2021
  • The article discusses the theoretical and methodological part that characterizes and assessment of the current state of the theory of GR-activity, disclosed the essence and content of the concept of GR-technologies, as well as their classification. The analysis of the system of additional education for children in the social structure, as well as the analysis of the current state of the education system is carried out. The formulation of tasks for the construction of an effective model for the use of GR-technologies in the process of developing the education system using GR-technologies

The Role of Innovative Work Behavior in Management of Public Transportation in Indonesia

  • Gusti Anisa, WULANDARI;Dewi, SUSITA;Mohammad Sofwan, EFFENDI
    • The Journal of Asian Finance, Economics and Business
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    • v.10 no.2
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    • pp.235-245
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    • 2023
  • This study examines the low performance of state civil servants related (ASN) to the management of public transportation at the Directorate of Road Transport (DRT), Ministry of Transportation, Indonesia. This study surveyed 103 ASNs, using a quantitative approach using the Amos SEM software. The results showed that Knowledge Sharing (KS) and Work Engagement (WE) directly influenced Innovative Work Behavior (IWB) as well as Job Performance (JP). Meanwhile, IWB had a significant, direct effect on JP and acts as a full mediator in the effect of KS and WE on JP. The descriptive data obtained also showed that respondents' statements based on gender have differences related to the IWB variable, where on average, women were better than men. However, for other variables (JP, KS, and WE), the data showed that, on average, the statements of male respondents were better than women. This study recommends that the DRT pay attention to IWB as a key factor mediating KS and WE towards increasing JP by maintaining the best indicators and improving the weakest indicators. Furthermore, this study recommends that future research refine these results by adding the variables of gender and educational level of the respondents.

Dynamic analysis of buildings considering the effect of masonry infills in the global structural stiffness

  • de Souza Bastos, Leonardo;Guerrero, Carolina Andrea Sanchez;Barile, Alan;da Silva, Jose Guilherme Santos
    • Coupled systems mechanics
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    • v.8 no.2
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    • pp.169-184
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    • 2019
  • This research work presents a study that aims to assess the dynamic structural behaviour and also investigate the human comfort levels of a reinforced concrete building, when subjected to nondeterministic wind dynamic loadings, considering the effect of masonry infills on the global stiffness of the structural model. In general, the masonry fills most of the empty areas within the structural frames of the buildings. Although these masonry infills present structural stiffness, the common practice of engineers is to adopt them as static loads, disregarding the effect of the masonry infills on the global stiffness of the structural system. This way, in this study a numerical model based on sixteen-storey reinforced concrete building with 48 m high and dimensions of $14.20m{\times}15m$ was analysed. This way, static, modal and dynamic analyses were carried out in order to simulate the structural model based on two different strategies: no masonry infills and masonry infills simulated by shell finite elements. In this investigation, the wind action is considered as a nondeterministic process with unstable properties and also random characteristics. The fluctuating parcel of the wind is decomposed into a finite number of harmonic functions proportional to the structure resonant frequency with phase angles randomly determined. The nondeterministic dynamic analysis clearly demonstrates the relevance of a more realistic numerical modelling of the masonry infills, due to the modifications on the global structural stiffness of the building. The maximum displacements and peak accelerations values were reduced when the effect of the masonry infills (structural stiffness) were considered in the dynamic analysis. Finally, it can be concluded that the human comfort evaluation of the sixteen-storey reinforced concrete building can be altered in a favourable way to design.

Impact of COVID-19 Pandemic on Use of Reference Sources and Services by Postgraduates' in Kenneth Dike Library, University of Ibadan, Nigeria

  • Samson Oyeyini Akande;Olalekan Abraham Adekunjo
    • International Journal of Knowledge Content Development & Technology
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    • v.13 no.1
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    • pp.27-41
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    • 2023
  • The outbreak of the corona virus diseases (COVID-19) in the late 2019 has affected all facets of educational system including library and information services. Reference services, an important aspect of library services are not exempted from this impact. This study therefore, investigated the impact of COVI\D-19 pandemic on the use of reference services and sources by postgraduate students using Kenneth Dike Library (KDL), University of Ibadan, as a case study. Using descriptive survey of correlational type, the study adopted the use of structured questionnaire to randomly select three hundred (300) postgraduate users of reference sources and services in KDL using online survey monkey. Of the three hundred (300) copies, two hundred and twenty three (223) copies, repre- senting 74.3% were retrieved and used for analysis. Findings revealed that, in spite of COVID-19 pandemic, most postgraduate students used Current Awareness Services (203, 91.0%, mean = 3.19), Reference Sources (202, 90.5%, mean = 3.18) and On-line Public Access Catalogue (195, 87.4%, mean = 3.13); low frequency of bibliotherapy (mean=2.22), Reader's Advisory services (mean=2.30) and inter-library loan (mean=2.13) and that COVID-19 pandemic had high impact on post- graduate students' use of reference services in Kenneth Dike Library, University of Ibadan. Based on the findings, recommendations were made that library management should consider the adoption of virtual reference services (VRS) in addition to the conventional mode of refer- ence services to enhance patronage in the COVID-19 era. The library users should also be trained on how to take advantage of the COVID-19 pandemic to learn new skills in the digital space that will eventually optimize the usage of the library remotely.

Improving the Role of the Teaching Hospital in the Clinical Clerkship (의과대학 학생 임상실습을 위한 교육병원의 역할 제고 방안)

  • Kim, Young Chang
    • Korean Medical Education Review
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    • v.17 no.1
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    • pp.10-14
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    • 2015
  • The mission of the modern medical school includes education, research, and patient care. The clinical clerkship is an important part of the core curriculum, and hospital facilities are needed for the clinical clerkship. However, unfortunately, education has moved to the periphery during the past several decades because of the dominance of research and patient care. This may lead to obstacles in the education of future physicians in the long term. To promote their education mission, teaching hospitals need to recognize and share the importance of this mission. In addition to the certification of teaching hospitals, a new paradigm for teaching hospitals should be introduced to produce a high quality clinical clerkship and postgraduate medical education. The relevant government departments need to allocate and expand financial support to medical schools and teaching hospitals, and to unify supervision of basic and postgraduate medical education.

Numerical formulation of a new solid-layer finite element to simulate reinforced concrete structures strengthened by over-coating

  • Suarez-Suarez, Arturo;Dominguez-Ramírez, Norberto;Susarrey-Huerta, Orlando
    • Coupled systems mechanics
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    • v.11 no.5
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    • pp.439-458
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    • 2022
  • Over-coating is one of the most popular engineering practices to strengthen Reinforced Concrete (RC) structures, due to the relative quickness and ease of construction. It consists of an external coat bonded to the outer surface of the structural RC element, either by the use of chemical adhesives, mechanical anchor bolts or simply mortar injection. In contrast to these constructive advantages, the numerical estimation of the bearing capacity of the strengthened reinforced concrete element is still complicated, not only for the complexity of modelling a flexible membrane or plate attached to a quasi-rigid solid, but also for the difficulties that raise of simulating any potential delamination between both materials. For these reasons, the standard engineering calculations used in the practice remain very approximated and clumsy. In this work, we propose the formulation of a new 2D solid-layer finite element capable to link a solid body with a flexible thin layer, as it were the "skin" of the body, allowing the potential delamination between both materials. In numerical terms, this "skin" element is intended to work as a transitional region between a solid body (modelled with a classical formulation of a standard quadrilateral four-nodes element) and a flexible coat layer (modelled with cubic beam element), dealing with the incompatibility of Degrees-Of-Freedom between them (two DOF for the solid and three DOF for the beam). The aim of the solid-layer element is to simplify the mesh construction of the strengthened RC element being aware of two aspects: a) to prevent the inappropriate use of very small solid elements to simulate the coat; b) to improve the numerical estimation of the real bearing capacity of the strengthened element when the coat is attached or detached from the solid body.