• Journal of Chest Surgery
• /
• 제26권10호
• /
• pp.798-800
• /
• 1993

VSD after myocardial infarction is and infrequent but often catastrophic complication. Occasionally, patient can be treated conservatively until an interval 3-4 wks post infarction.We successively treated ventricular septal defect, 4wks after anterior myocardial infarction.

• Journal of Chest Surgery
• /
• 제44권2호
• /
• pp.186-188
• /
• 2011

Ventricular septal rupture (VSR) is a rare but lethal complication of myocardial infarction. The event occurs 2~8 days after an infarction and often precipitates cardiogenic shock. Post myocardial infarction VSR is known for difficult to repair. Especially, Transmural myocardial infarction involved in the posterior VSD area, exposure of the affected site is difficult and postoperative mortality rate is high. We have experienced a case of a 75-year-old female patient who suffered posterior VSD due to acute myocardial infarction, and attained good result by approaching the lesion through right atrial incision and repaired the defect by using patch closure technique.

• 한국전문물리치료학회지
• /
• 제1권1호
• /
• pp.83-87
• /
• 1994

The purpose of this paper is to provide an overview of the clinical physical therapy program used at the University of Yonsei Rehabilitation Hospital, for the practicing university trained physical therapists who may be unfamiliar with patients who have suffered a myocardial infarction. The four primary phases of the cardiac physical therapy graded exercise program are: 1) coronary care unit program (phase I), 2) general ward program (phase II), 3) convalescence program (phase III), 4) maintenance program (phase IV). The exercise prescription defines the exercise intensity, duration, frequency, and mode of exercise a after pre- discharge low level graded exercise test(LL-GXT) or symptom limited maximum graded exercise test. A typical exercise routine consists of preparation warm-up exercise, therapeutic exercise, cool-down exercise. Physical therapy is involved in the acute care and rehabilitation of the patient after a myocardial infarction. Therefore, the physical therapist must throughly comprehened the cardiac anatomy, cycle, performance, conduction system, pathogenesis, risk factors, and exercise benefits.

• 성인간호학회지
• /
• 제14권4호
• /
• pp.573-580
• /
• 2002

Purpose: The purpose of this study was to investigate the effects of a cardiac rehabilitation program for patients with myocardial infarction. Method: The subjects were 45 myocardial infarction patients(22 for experimental group and 23 for the control group). Data were collected through questionnaire survey, blood test, and the treadmill test, between October 1, 1999 and December 31, 2000. As for data analyses, paired and unpaired t-test and $\chi^2$ test were adopted using the SAS program. Result: 1. The post-test revealed that increase in compliance score of health behavior was significantly higher in the experimental group than in the control group. 2. The increase in HDL cholesterol was significantly higher in the experimental group than in the control group, in the post-test. 3. The experimental group showed significantly higher duration of exercise time and maximal METs than the control group after the program. Conclusion: The above findings indicate that a cardiac rehabilitation program was effective in increasing compliance of health behaviors, serum HDL cholesterol level, duration of exercise time, and maximal METs in patients with myocardial infarction. Accordingly, we can adopt the individualized cardiac rehabilitation programs as a nursing intervention.

• 대한핵의학회지
• /
• 제23권1호
• /
• pp.19-25
• /
• 1989

To assess the usefulness of myocardial SPECT imaging to detect post-myocardial infarction ventricular aneurysms, we analyzed the Technetium-99m MIBI myocardial SPECT images of 16 patients with anterior and/or apical infarction, 9 had the previously reported findings of failure of convergence of the left ventricular walls toward the apex on SPECT images and 8 of them also had ventricular aneurysms. The ventriculography of the 2 patients with mixed pattern revealed 1 case of ventricular aneurysm and 1 case without aneurysm. Among the remaining 5 pateints with converging pattern, none had ventricular aneurysm. Of the other 11 pateints with inferior and/or lateral wall infarction, 1 patient had ventricular aneurysm and the SPECT image couldn't detect the aneurysm. $Department of Internal Medicine, College of Medicine, Seoul National University$ myocardial SPECT images for the detection of ventricular aneurysm had a sensitivity of 90 %, a specificity of 88%, and an accuracy of 89%. Thus we could get the information about presence of ventricular aneurysm as well as the status of the myocardial perfusion from the Tc-99m MIBI myocardial SPECT images.

• 한국응급구조학회지
• /
• 제20권2호
• /
• pp.7-19
• /
• 2016

연구 목적: 본 연구에서는 심근경색 쥐 모델에서 심장정지를 유발시킨 후 심폐소생술을 수행하는 과정에서 조기 저체온 치료를 적용하여 심장근육의 기능회복과 생존율에 미치는 효과를 조사하고자 하였다. 연구 방법: 본 연구를 위하여 체중 450-550g의 수컷 Sprague Dawley 쥐 10 마리에 개흉을 실시하였다. 왼내림심장동맥을 묶어서 심근경색을 유발시켰다. 왼내림심장동맥을 묶은 후 90분 동안 심실세동을 유도하고, 심폐소생술과 제세동을 실시하였다. 대조군(정상체온군)은 회복과정에 정상체온으로 유지한 군이며, 실험군(저체온군)은 회복과정에 $32^{\circ}C$ 4시간 저체온을 유지한 군이다. 연구 결과: 심박출량, 좌심실박출률, 심근수행지수는 심폐소생술 후 첫 4시간 동안 대조군보다 실험군에서 더 양호하게 나타났다. 실험군의 생존시간은 대조군보다 더 길게 나타났다(p<.050). 결 론: 본 연구를 통하여 조기 저체온 치료의 적용이 급성심근경색의 심폐소생술 후 심장 기능을 개선하는 데 탁월한 효과가 있으며, 치료법의 새로운 기준이 될 것이다.

• 대한간호학회지
• /
• 제19권1호
• /
• pp.108-117
• /
• 1989

The purpose of this study was to identify factors related to daily activities of post myocardial infarction patients. Data were collected from Aug. 1 to Aug. 31, 1988 through an interview schedule lasting for about 30~60 minutes by the investigators. Tools for this study were a daily activities scale and a subjective physical symptom scale developed by the researchers, and Zung's self rating depression scale. The subjects were 45 men 18 women post myocardial infarction patients who were receiving follow up care at SNU Hospital. The data were analyzed by percentage, mean t-test ANOVA, the Pearson moment Correlation Coefficient test, and Cronbach's $\alpha$ reliability test. The results were as follows. \circled1 Reliability of the daily activities scale was 0.91 by Cronbach's $\alpha$. In the daily activities scale, items about transfer, exercise, and job related activities were most highly rated as meaningful to the post myocardial infarction patients. \circled2 The average daily activities score of these patients was 3.30 (maximum point ; 4) all scores were high except for exercise and job related activities. \circled3 There was a significant difference in daily activities according to sex ; men had a higher daily activities score than women (T＝2.32, p＜0.05). \circled4 There was a significant difference in daily activities according to job status. Subjects having a job had a higher daily activities score. \circled5 The lower the depression score, the higher the daily activities score(${\gamma}$＝-0.5748, P＜0.05). \circled6 The lower the subjective physical symptoms score, the higher the daily activities score(${\gamma}$＝ -0.6015, p＜0.05).

• 대한간호학회지
• /
• 제32권1호
• /
• pp.50-61
• /
• 2002

The purpose of this study was to investigate the effects of cardiac rehabilitation teaching program on knowledge level and compliance of health behavior for the patients with myocardial infarction. Method: The subjects were 47 patients 23 were assigned to the experimental group and 24 were for the control. The cardiac rehabilitation teaching program is a individualized teaching program which was delivered to the experimental group during hospitalization period by present researcher. Data were collected through questionnaire surveys for knowledge level and compliance of health behavior from September 15, 1999 to December 31, 2000. The collected data was analyzed by using the SAS program. Results: 1. With regard to the knowledge scores 1) The total knowledge level in the experimental group was significantly higher than in the control group. 2) As to the knowledge domains, nature of disease, risk factors, diet, medication, exercise, and daily activities were significantly higher in score in the experimental group than in the control group. 2. With regard to the compliance of health behavior 1) The average compliance with good health behavior was significantly higher in the experimental group than in the control group. 2) As to the health behavior domains smoking cessation, diet, stress management, regular exercise, and other measures for lifestyle modification were significantly higher in score in the experimental group than in the control group. 3. The pre-treatment knowledge score was positively correlated to the post-treatment knowledge score and post- treatment knowledge score was positively correlated to the post-treatment compliance of health behaviors. Conclusion: The above findings indicate that the cardiac rehabilitation teaching program for the experimental group was effective in increasing level of knowledge and improvement of compliance with good health behavior of patients with myocardial infarction.

• Journal of Ginseng Research
• /
• 제47권6호
• /
• pp.743-754
• /
• 2023

Background: Myocardial fibrosis post-myocardial infarction (MI) can induce maladaptive cardiac remodeling as well as heart failure. Although 20(S)-ginsenoside Rg3 (Rg3) has been applied to cardiovascular diseases, its efficacy and specific molecular mechanism in myocardial fibrosis are largely unknown. Herein, we aimed to explore whether TGFBR1 signaling was involved in Rg3's anti-fibrotic effect post-MI. Methods: Left anterior descending (LAD) coronary artery ligation-induced MI mice and TGF-β1-stimulated primary cardiac fibroblasts (CFs) were adopted. Echocardiography, hematoxlin-eosin and Masson staining, Western-blot and immunohistochemistry, CCK8 and Edu were used to study the effects of Rg3 on myocardial fibrosis and TGFBR1 signaling. The combination mechanism of Rg3 and TGFBR1 was explored by surface plasmon resonance imaging (SPRi). Moreover, myocardial Tgfbr1-deficient mice and TGFBR1 adenovirus were adopted to confirm the pharmacological mechanism of Rg3. Results: In vivo experiments, Rg3 ameliorated myocardial fibrosis and hypertrophy and enhanced cardiac function. Rg3-TGFBR1 had the 1.78×10^-7 M equilibrium dissociation constant based on SPRi analysis, and Rg3 inhibited the activation of TGFBR1/Smads signaling dose-dependently. Cardiac-specific Tgfbr1 knockdown abolished Rg3's protection against myocardial fibrosis post-MI. In addition, Rg3 downregulated the TGF-β1-mediated CFs growth together with collagen production in vitro through TGFBR1 signaling. Moreover, TGFBR1 adenovirus partially blocked the inhibitory effect of Rg3. Conclusion: Rg3 improves myocardial fibrosis and cardiac function through suppressing CFs proliferation along with collagen deposition by inactivation of TGFBR1 pathway.

• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 1994년도 교수 연수회(역학)
• /
• pp.180-187
• /
• 1994

A slightly modified version of the Quality-of-Life after Myocardial Infarction (QLMI) questionnaire developed by Oldridge and colleagues was applied in a self-administered mode to patients with suspected acute myocardial infarction (AMI) in a randomized controlled trial of secondary prevention. Acceptability of the questionnaire was good, with 93% of responders answering all items. Factor analysis suggested three quality-of-life (QL) dimensions which we called 'emotional', 'physical' and 'social'. These differed somewhat from the dimensions proposed by Oldtidge and colleagues. However, a sensitivity analysis showed relative invariance of results to weighting schemes. Scores on our three dimensions were responsive to differences between the treatment groups, and demonstrated construct validity based on associations between the measured QL and variables expected to affect QL. We conclude that the QLMI questionnaire has good potential as an instrument for assessing QL in post-AMI patients and that it can be successfully self-administered.