• Title/Summary/Keyword: Portal System

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Experimental Applications of in situ Liver Perfusion Machinery for the Study of Liver Disease

  • Choi, Won-Mook;Eun, Hyuk Soo;Lee, Young-Sun;Kim, Sun Jun;Kim, Myung-Ho;Lee, Jun-Hee;Shim, Young-Ri;Kim, Hee-Hoon;Kim, Ye Eun;Yi, Hyon-Seung;Jeong, Won-Il
    • Molecules and Cells
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    • v.42 no.1
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    • pp.45-55
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    • 2019
  • The liver is involved in a wide range of activities in vertebrates and some other animals, including metabolism, protein synthesis, detoxification, and the immune system. Until now, various methods have been devised to study liver diseases; however, each method has its own limitations. In situ liver perfusion machinery, originally developed in rats, has been successfully adapted to mice, enabling the study of liver diseases. Here we describe the protocol, which is a simple but widely applicable method for investigating the liver diseases. The liver is perfused in situ by cannulation of the portal vein and suprahepatic inferior vena cava (IVC), with antegrade closed circuit circulation completed by clamping the infrahepatic IVC. In situ liver perfusion can be utilized to evaluate immune cell migration and function, hemodynamics and related cellular reactions in each type of hepatic cells, and the metabolism of toxic or other compounds by changing the composition of the circulating media. In situ liver perfusion method maintains liver function and cell viability for up to 2 h. This study also describes an optional protocol using density-gradient centrifugation for the separation of different types of hepatic cells, allowing the determination of changes in each cell type. In summary, this method of in situ liver perfusion will be useful for studying liver diseases as a complement to other established methods.

Regional Distribution Characteristics and Meanings of Women-only Shared Housings - A Case Study of Agency-managed Shared Housings in Seoul - (여성전용 셰어하우스의 지역 분포특성과 의미에 관한 연구 - 서울의 운영사 관리형 현장 사례를 중심으로 -)

  • Kim, Nasung;Park, So-Hyun
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.35 no.4
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    • pp.3-14
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    • 2019
  • The purpose of this study is to analyze the distribution characteristics of the agency-managed shared housings in Seoul and draw the possible implications from it. The needed data for the study was obtained from an on-line shared housing portal service which provides housing information from various shared housing management agencies. By mapping out the locations and other related data into a GIS(Geographic Information System) program, this study shows that shared housings in Seoul can be sorted into four large clusters. Each cluster has a different ratio of housing types and room capacities reflecting each regional circumstance and common causes. Women-only shared housing takes up 79% of the overall shared housing ratio and, while multi-family housing type has the most count, the apartment type has a noticeably high ratio in women-only housing compared to the apartment type ratio among the other gender-specific housings. Given the high crime rate against the single-person household of young adult women, the reason for the popularity of shared-apartment housing among young women can be deduced. However, the potential tenants' practical choices and their concern for safety are not the only causes that drive the current shared housing market. The young adults in their 20's and 30's choose to live in popular places where they can engage social activities. A new tier of shared housing market has also appeared in places where young adults could not have afforded if they lived alone. Choosing where we live is no longer about just meeting the requirements for a house based on what she/he needs but also about satisfying the preferences for a living based on what she/he desires. This paper indicates that although there is an undeniable premise that 'sharing a house' revolves around the realm of housing welfare and is not a typical topic for the upper-income households, the way we live and how we choose our place to live is shifting.

The Comparison Between the Comments and the Replies on Korean President Election News: using Topic Modeling (대선 관련 인터넷 뉴스의 댓글과 대댓글 간 비교를 통해 살펴본 온라인 토론의 진행 가능성)

  • Lee, Jung
    • Journal of Intelligence and Information Systems
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    • v.28 no.2
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    • pp.33-55
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    • 2022
  • This study analyzed the comments and the replies on internet news related to the presidential election in order to verify whether online discussions are properly conducted. According to Habermas' public sphere theory, discussions is an effort among participants to reach a social consensus through the deliberations that are based on open communications. We propose that if such discussions properly take place through the act of writing in the Internet space, the comments and the replies will show a certain difference in terms of the structure and the content. To validate, this study analyzed more than 40,000 comments collected from Daum News portal site in Korea. The topic of the related news was the presidential election, because it is a topic of which people are highly interested in and that comments are actively running. The result of the t-test and topic modeling result show that all the hypotheses were supported thus we conclude that online discussions properly took places. This study also showed that online comments are not chaotic remarks that relieve people's stresses, but rather an outcome of the deliberation processes moving towards a social consensus.

Effect of Total Collimation Width on Relative Electron Density, Effective Atomic Number, and Stopping Power Ratio Acquired by Dual-Layer Dual-Energy Computed Tomography

  • Jung, Seongmoon;Kim, Bitbyeol;Yoon, Euntaek;Kim, Jung-in;Park, Jong Min;Choi, Chang Heon
    • Progress in Medical Physics
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    • v.32 no.4
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    • pp.165-171
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    • 2021
  • Purpose: This study aimed to evaluate the effect of collimator width on effective atomic number (EAN), relative electron density (RED), and stopping power ratio (SPR) measured by dual-layer dual-energy computed tomography (DL-DECT). Methods: CIRS electron density calibration phantoms with two different arrangements of material plugs were scanned by DL-DECT with two different collimator widths. The first phantom included two dense bone plugs, while the second excluded dense bone plugs. The collimator widths selected were 64 mm×0.625 mm for wider collimators and 16 mm×0.625 mm for narrow collimators. The scanning parameters were 120 kVp, 0.33 second gantry rotation, 3 mm slice thickness, B reconstruction filter, and spectral level 4. An image analysis portal system provided by a computed tomography (CT) manufacturer was used to derive the EAN and RED of the phantoms from the combination of low energy and high energy CT images. The EAN and RED were compared between the images scanned using the two different collimation widths. Results: The CT images with the wider collimation width generated more severe artifacts, particularly with high-density material (i.e., dense bone). RED and EAN for tissues (excluding lung and bones) with the wider collimation width showed significant relative differences compared to the theoretical value (4.5% for RED and 20.6% for EAN), while those with the narrow collimation width were closer to the theoretical value of each material (2.2% for EAN and 2.3% for RED). Scanning with narrow collimation width increased the accuracy of SPR estimation even with high-density bone plugs in the phantom. Conclusions: The effect of CT collimation width on EAN, RED, and SPR measured by DL-DECT was evaluated. In order to improve the accuracy of the measured EAN, RED, and SPR by DL-DECT, CT scanning should be performed using narrow collimation widths.

Review on Cases Applying Hwangryunhaedok-tang External Agent in Korea (황련해독탕(黃連解毒湯) 외용제를 적용한 국내 치험례 고찰)

  • Choi, Min-A;Kim, Kyu-Seok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.35 no.1
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    • pp.48-57
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    • 2022
  • Objectives : The purpose of this review study is to identify clinical indications of Hwangryunhaedok-tang(HHT) external application and to suggest directions for future research and treatment by analyzing domestic cases applying HHT external treatment except for pharmacopuncture research. Methods : We searched 235 studies published in Korean since 2000 from four domestic databases: Oriental Medicine Advanced Searching Integrated System(OASIS), Research Information Sharing Service(RISS), Korean Traditional Knowledge Portal(KTKP), and Korean studies Information Service Systems(KISS) using keywords such as 'HTT and external use', 'HHT and external agent' 'HHT and wet dressing', or 'HHT and case'. We excluded duplicate papers, papers related to acupuncture including pharmacopuncture, or papers not related to the topic. Results : We selected and analyzed seven case reports. HHT external agent was used alone in one case, as main treatment in two cases, and as adjuvant treatment in four cases. HHT external application was applied to various skin diseases accompanied by inflammation mainly in the form of wet dressings. Conclusion : HHT external agent may be effective on various skin diseases accompanied by inflammation when applied alone or in combination with other agents according to the treatment stage. Based on this results, further studies will be needed to establish the primary clinical indication of HHT external agent.

Trends of Studies in Journal of Korean Medicine Rehabilitation: Focused on Diseases and Treatment for Recent 10 years (한방재활의학과학회지의 연구동향: 최근 10년간의 연구들을 질환과 치료법 중심으로)

  • Ji-Hong Jeong;Hong-Ryoul Yoon;Soon-Joong Kim
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.1
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    • pp.61-75
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    • 2023
  • Objectives The purpose of this study is to find out what diseases or treatments the Korean Medicine Rehabilitation department is dealing with. Methods For data collection, papers published from 2012 to 2021 were searched and collected on the website of the Korean Society of Rehabilitation Medicine (https://www.ormkorea.org/). After that, reconfirmed data at the Oriental Medicine Advanced Searching Integrated System (OASIS) Traditional Medicine Portal (https://oasis.kiom.re.kr/). The searched papers were classified by year and classified according to format based on thesis and abstract. In addition, the papers were classified by subject, focusing on diseases and treatments. Results Total 557 studies were classified. The format of a total of 557 papers was distributed in 129 preclinical studies (23.2%), 136 literature studies (24.4%), 153 clinical studies (27.5%), 112 case reports (20.1%), and 27 other studies (4.8%). While preclinical studies and clinical studies are gradually decreasing over the years, case reports and literature studies are gradually increasing. Conclusions The number of papers in Journal of Korean Medicine Rehabilitation is gradually decreasing. Papers on more diverse topics is needed for the qualitative growth of journals and Department of Korean Medicine Rehabilitation.

A Study on the Analysis and Expansion Plan of Public Library Services in the COVID-19 Pandemic (코로나19에 대응하는 공공도서관 서비스 분석 및 확대방안 연구)

  • Seon-Kyung Oh
    • Journal of the Korean Society for Library and Information Science
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    • v.57 no.3
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    • pp.119-141
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    • 2023
  • The COVID-19 pandemic has significantly changed the landscape of knowledge and information services that public libraries around the world have been providing since modern times. In particular, as social distancing has become routine, the contraction of cultural activities and the shift to online platforms have negatively impacted library visitation and use services, greatly reducing borrowing and reading, use of spaces and facilities, interlibrary loan services, program operations, and outreach services. Therefore, this study investigated and analyzed the current status of services provided by public libraries in Korea and abroad in response to COVID-19, and proposed practical ways to improve and expand services in response to COVID-19 based on the results of a survey of librarians' perceptions. Specifically, these include improving the online reservation system for reading and borrowing services and developing and providing various outreach services, acquiring and expanding electronic resources, expanding online program services (reading, culture, lifelong learning, etc.), strengthening library services for vulnerable populations, providing information portal services related to new infectious diseases, strengthening facilities and space provision services, preparing infectious disease response guidelines, and providing education and training to strengthen librarians' capabilities.

Modeling and Implementation of Multilingual Meta-search Service using Open APIs and Ajax (Open API와 Ajax를 이용한 다국어 메타검색 서비스의 모델링 및 구현)

  • Kim, Seon-Jin;Kang, Sin-Jae
    • Journal of Korea Society of Industrial Information Systems
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    • v.14 no.5
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    • pp.11-18
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    • 2009
  • Ajax based on Java Script receives attention as an alternative to ActiveX technology. Most portal sites in korea show a tendency to reopen existing services by combining the technology, because it supports most web browsers, and has the advantages of such a brilliant interface, excellent speed, and traffic reduction through asynchronous interaction. This paper modeled and implemented a multilingual meta-search service using the Ajax and open APIs provided by international famous sites. First, a Korean query is translated into one of the language of 54 countries around the world by Google translation API, and then the translated result is used to search the information of the social web sites such as Flickr, Youtube, Daum, and Naver. Searched results are displayed fast by dynamic loading of portion of the screen using Ajax. Our system can reduce server traffic and per-packet communications charges by preventing redundant transmission of unnecessary information.

A Construction of Management System and Its Portal Site for NTIS Data Quality Management (NTIS 데이터 품질관리 체계와 포털 사이트 구축)

  • Lee, Byeong-Hee;Jung, Ock-Nam;Choi, Heeseok;Lim, ChulSu;Kim, Jaesoo
    • Proceedings of the Korea Information Processing Society Conference
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    • 2009.04a
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    • pp.984-987
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    • 2009
  • 데이터가 기업 및 기관 활동의 중요한 자산으로 인식이 높아지고 있지만 저 품질 데이터로 인한 막대한 손실과 비용의 증가는 큰 문제가 되고 있다. 본 논문에서는 교육과학기술부와 KISTI에서 2007년부터 범부처 차원에서 수행중인 국가R&D 정보자원의 데이터 품질관리를 위해 각 부처와 협의하고 수행해 온 국가R&D 데이터 품질관리 체계 수립과 포털 사이트 구축에 관하여 알아본다. 범부처 국가R&D정보 자원의 데이터 품질관리체계 수립과 범부처 적용 지침 및 가이드라인 제시를 위해 NTIS사업단 및 15개 부처(16개 대표전문기관)의 실무팀장 및 DB 관리자 중심으로 총 33명의 설문을 실시하여 품질관리체계 현황을 조사 분석하였다. 또한 부처(기관)별로 국가R&D표준정보 데이터품질 지표 마련과 주기별 데이터 품질 및 개선도 자체점검을 지원하기 위해, 데이터 점검기준과 절차를 마련하고 이를 기반으로 부처(기관)와 협력하여 데이터품질 점검을 기반을 마련하였다. 이렇게 마련된 품질관리체계와 프로세스를 지원하기 위한 자동화 솔루션을 운영하고자 본 논문에서는 NTIS 데이터 품질관리 체계 및 프로세스, 기능이 통합된 웹 포털 구축에 대해서도 알아본다.

Prediction Model of Real Estate Transaction Price with the LSTM Model based on AI and Bigdata

  • Lee, Jeong-hyun;Kim, Hoo-bin;Shim, Gyo-eon
    • International Journal of Advanced Culture Technology
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    • v.10 no.1
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    • pp.274-283
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    • 2022
  • Korea is facing a number difficulties arising from rising housing prices. As 'housing' takes the lion's share in personal assets, many difficulties are expected to arise from fluctuating housing prices. The purpose of this study is creating housing price prediction model to prevent such risks and induce reasonable real estate purchases. This study made many attempts for understanding real estate instability and creating appropriate housing price prediction model. This study predicted and validated housing prices by using the LSTM technique - a type of Artificial Intelligence deep learning technology. LSTM is a network in which cell state and hidden state are recursively calculated in a structure which added cell state, which is conveyor belt role, to the existing RNN's hidden state. The real sale prices of apartments in autonomous districts ranging from January 2006 to December 2019 were collected through the Ministry of Land, Infrastructure, and Transport's real sale price open system and basic apartment and commercial district information were collected through the Public Data Portal and the Seoul Metropolitan City Data. The collected real sale price data were scaled based on monthly average sale price and a total of 168 data were organized by preprocessing respective data based on address. In order to predict prices, the LSTM implementation process was conducted by setting training period as 29 months (April 2015 to August 2017), validation period as 13 months (September 2017 to September 2018), and test period as 13 months (December 2018 to December 2019) according to time series data set. As a result of this study for predicting 'prices', there have been the following results. Firstly, this study obtained 76 percent of prediction similarity. We tried to design a prediction model of real estate transaction price with the LSTM Model based on AI and Bigdata. The final prediction model was created by collecting time series data, which identified the fact that 76 percent model can be made. This validated that predicting rate of return through the LSTM method can gain reliability.