• Title/Summary/Keyword: Population-averaged effect

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Autoregressive Cholesky Factor Modeling for Marginalized Random Effects Models

  • Lee, Keunbaik;Sung, Sunah
    • Communications for Statistical Applications and Methods
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    • v.21 no.2
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    • pp.169-181
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    • 2014
  • Marginalized random effects models (MREM) are commonly used to analyze longitudinal categorical data when the population-averaged effects is of interest. In these models, random effects are used to explain both subject and time variations. The estimation of the random effects covariance matrix is not simple in MREM because of the high dimension and the positive definiteness. A relatively simple structure for the correlation is assumed such as a homogeneous AR(1) structure; however, it is too strong of an assumption. In consequence, the estimates of the fixed effects can be biased. To avoid this problem, we introduce one approach to explain a heterogenous random effects covariance matrix using a modified Cholesky decomposition. The approach results in parameters that can be easily modeled without concern that the resulting estimator will not be positive definite. The interpretation of the parameters is sensible. We analyze metabolic syndrome data from a Korean Genomic Epidemiology Study using this method.

Use of Generalized Linear Mixed Model for Pest Density in Repeated Measurement Data

  • Park, Heung-Sun;Cho, Ki-Jong
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.05a
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    • pp.69-74
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    • 2003
  • The estimation of pest density is a prime concern of Integrated Pest Management (IPM) because the success of artificial intervention such as spraying pestcides or natural enemies depends on pest density. Also, the spatial pattern of pest population within plants or plots has been studies in various ways. In this study, we applied generalized linear mixed model to Tetranychus urticae Koch , two-spotted spider mite count in glasshouse grown roses. For this analysis, the subject-specific as well as pupulation-averaged approaches are used.

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Function of Home Energy Savings and Carbon Emission Reduction by Urban Vegetation- Case of Chuncheon- (도시식생의 주택에너지절약 및 탄소배출저감 기능 -춘천시를 대상으로-)

  • 조현길;서옥하;한갑수
    • Journal of the Korean Institute of Landscape Architecture
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    • v.26 no.3
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    • pp.104-117
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    • 1998
  • Rising concern about climate change has evoked interest in the potential for urban vegetation to help reduce the level of atmospheric CO\sub 2\, a major heat-trapping gas. This study quantified the functio of home energy savings and carbon emission reduction by shading, evapotranspiration and windspeed reduction of urban vegetatioin in Chuncheon. Tree and shrub cover averaged approximately 13% in residential land. The effects of shading, evapotranspiration and windspeed reduction annually saved heating energy by 2.2% and cooling energy by 8.8%. The heating and cooling energy savings reduced carbon emissions by 3.0% annually. These avoided emissions equaled the amount of carbon emitted annually from fossil fuel consumption by a population of about 1,230. Carbon emission reduction per residential building was 55kg for detached buildings and 872 kg for multifamily buildings. Urban vegetation annually decreased heating and cooling energy cost by ₩1.1 billions, which were equivalent to annual savings of ₩10,000 savings and carbon emission reduction due to tree plantings in the wrong locations, while windspeed reduction had a great effect. Plantings fo large trees close to the west and east wall of buildings, full tree plantings on the north, and avoidance of shade-tree plantings or selection of solar-friendlytrees on the south were recommended to improve the function of building energy savings and carbon emission reduction by urban vegetation.

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Effects of Induced Fatigue of Ankle Joint Muscle on the Capability and Recovery of Postural Control during Single-Leg Stance (발목 관절 근육의 유도된 피로가 외발서기 자세제어 능력과 회복에 미치는 영향)

  • Youm, Chang-Hong;Kim, Tae-Hyeon
    • Korean Journal of Applied Biomechanics
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    • v.22 no.2
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    • pp.219-228
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    • 2012
  • The purpose of this study was to investigate how induced fatigue of the ankle joint muscles affects the capability and recovery of postural control during single-leg stance in healthy adults. The study population included 22 randomly recruited men and women. Postural control was performed on single-leg stance with eyes open. Ankle joint muscle was fatigued by repeated heel raises. According to the results of this study, for the anteroposterior variables, both men and women showed significantly increased center of mass velocity and decreased center of pressure 95% edge frequency immediately after fatigue. For the mediolateral variables, both men and women showed significantly increased center of mass velocity and decreased center of pressure 95% edge frequency immediately after fatigue. For the total variables, both men and women showed significantly increased center of mass averaged-velocity immediately after fatigue, and also, the center of pressure 95% confidence ellipse area significantly increased in women. Postural control variables were not significantly different for men and women at any time (Pre, P0, P10, and P20). In conclusion, the gender does not affect the capability and recovery after induced fatigue of ankle joint muscles. The effect of fatigue found for the anteroposterior and the mediolateral variables in both men and women. Furthermore ankle joint muscle fatigue led to change of postural control strategy from an ankle joint strategy towards a hip joint strategy. These changes are believed to damage postural control. The ankle joint muscle recovered from fatigue within 20 min during single-leg stance.

Effect of Thermal Stratification and Mixing on Phytoplankton Community Structure in the Western Channel of the Korea Strait

  • Shon, Dong-Hyun;Shin, Kyoung-Soon;Jang, Pung-Guk;Kim, Young-Ok;Chang, Man;Kim, Woong-Seo
    • Ocean and Polar Research
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    • v.30 no.3
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    • pp.261-275
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    • 2008
  • The profile of a fixed site at station M ($34.77^{\circ}N,\;129.13^{\circ}E$) in the Korea Strait was studied from March 2006 to February 2007. The aim was to understand the relationship between the annual thermal stratification pattern and seasonal variation in phytoplankton community structure. Physicochemical factors including temperature, salinity and nutrient concentrations, which strongly influence the proliferation and diversity of phytoplankton, were measured. The study period was divided into three due to the characteristic of thermohaline structures; mixed I (March-May 2006), stratified (June-November 2006) and mixed II(December 2006-Feburuary 2007). Diatoms dominated during the mixed I (89%) and II (48%) periods, while nanoplankton group occupied over 83% of total population during the stratified period. The dominant species during the mixed I and II was Chaetoceros socialis (47% and 29%, respectively), while during the stratified period Gyrodinium sp.(4%) was the most dominant. Averaged total chl a concentrations during the mixed I and II periods were 0.61 mg $m^{-3}$ and 0.72 mg $m^{-3}$, respectively, which were at least two-fold higher than that during the stratified period (0.30 mg $m^{-3}$). The vertical mixing and convection process of the water column induced nutrient supply from the bottom layer to the euphotic zone. It also led to the dominance of diatoms during the mixed periods, whereas small phytoplankton prevailed over large phytoplankton as stratification blocked the upward movement of nutrients to subsurface during the stratified period. During the mixed I and II periods, microplanktonic chl a dominated concentrations (50% and 48%, respectively), while picoplanktonic chl a occupied over 37% of total chl a during the stratified period.

A Comparative Review of Radiation-induced Cancer Risk Models

  • Lee, Seunghee;Kim, Juyoul;Han, Seokjung
    • Journal of Radiation Protection and Research
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    • v.42 no.2
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    • pp.130-140
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    • 2017
  • Background: With the need for a domestic level 3 probabilistic safety assessment (PSA), it is essential to develop a Korea-specific code. Health effect assessments study radiation-induced impacts; in particular, long-term health effects are evaluated in terms of cancer risk. The objective of this study was to analyze the latest cancer risk models developed by foreign organizations and to compare the methodology of how they were developed. This paper also provides suggestions regarding the development of Korean cancer risk models. Materials and Methods: A review of cancer risk models was carried out targeting the latest models: the NUREG model (1993), the BEIR VII model (2006), the UNSCEAR model (2006), the ICRP 103 model (2007), and the U.S. EPA model (2011). The methodology of how each model was developed is explained, and the cancer sites, dose and dose rate effectiveness factor (DDREF) and mathematical models are also described in the sections presenting differences among the models. Results and Discussion: The NUREG model was developed by assuming that the risk was proportional to the risk coefficient and dose, while the BEIR VII, UNSCEAR, ICRP, and U.S. EPA models were derived from epidemiological data, principally from Japanese atomic bomb survivors. The risk coefficient does not consider individual characteristics, as the values were calculated in terms of population-averaged cancer risk per unit dose. However, the models derived by epidemiological data are a function of sex, exposure age, and attained age of the exposed individual. Moreover, the methodologies can be used to apply the latest epidemiological data. Therefore, methodologies using epidemiological data should be considered first for developing a Korean cancer risk model, and the cancer sites and DDREF should also be determined based on Korea-specific studies.

The effect of dental hygiene students' knowledge and attitude toward the elderly on the discrimination of the elderly (치위생학과 학생들의 노인에 대한 지식 및 태도가 노인차별주의에 미치는 영향)

  • Young-Sun Kim;Jung-Hwa Lee
    • Journal of Korean Dental Hygiene Science
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    • v.6 no.2
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    • pp.129-139
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    • 2023
  • Background: The elderly population aged 65 or older in Korea is expected to continue to increase to 18.4% in 2023, and to enter a super-aged society at 20.6% in 2025. In clinical practice, the elderly discrimination of dental hygienists may experience difficulties during dental hygiene treatment due to an increase in the number of elderly patients due to aging, which can lead to maladjustment to work and turnover, so education on the understanding of the elderly is essential for students in the Department of Dentistry, who are prospective dental hygienists. Accordingly, a study was conducted to prepare for a super-aged society by studying the relationship between elderly discrimination and the knowledge and attitudes of the elderly, and to change the curriculum of universities and develop programs related to the elderly. Method: 204 students enrolled in the Department of Dentistry in D area were analyzed using the SPSS/WIN 25.0 program. The subject's geriatric discrimination, knowledge about the elderly, and attitude toward the elderly were calculated as the mean and standard deviation. T-test and one-way ANOVA were performed to verify the difference in geriatric discrimination according to the general characteristics of the subject, with a Scheffe' test applied for post-hoc analysis. Correlation analysis was conducted on the subject's geriatric discrimination, knowledge about the elderly, and attitudes toward the elderly. Results: Geriatrics scored 2.03±0.36 out of 4. Knowledge about the elderly was categorized as follows: physical domain 0.57±0.15; social domain 0.36±0.17; and psychological domain 0.35±0.20. The attitude toward the elderly was 3.86±0.27. Knowledge of the elderly averaged 11.27±3.30 points out of 25. The question with the highest percentage of correct answers to knowledge about the elderly was 'physical strength tends to decrease with age', which was 93.1%. The attitude toward the elderly according to the general characteristics of the study subjects showed significant differences in gender (p=0.040), age (p=0.026), and life experience with grandparents (p=0.001). The elderly discrimination of the study subjects showed a negative correlation in both attitude and knowledge toward the elderly, and among the elderly discrimination, there was a high positive correlation with regard to emotional avoidance (r=.892, p<0.001). Conclusion: College students are the leading players in caring for the elderly and are directly affected by aging social problems. Therefore, it is considered necessary to apply various programs in the state, society, and educational institutions to avoid negative prejudices that lead to positive thinking and discrimination against the elderly.