• 제목/요약/키워드: Population genetic structure

검색결과 460건 처리시간 0.027초

Genetic diversity analysis of fourteen geese breeds based on microsatellite genotyping technique

  • Moniem, Hebatallah Abdel;Zong, Yang Yao;Abdallah, Alwasella;Chen, Guo-hong
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권11호
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    • pp.1664-1672
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    • 2019
  • Objective: This study aimed to measure genetic diversity and to determine the relationships among fourteen goose breeds. Methods: Microsatellite markers were isolated from the genomic DNA of geese based on previous literature. The DNA segments, including short tandem repeats, were tested for their diversity among fourteen populations of geese. The diversity was tested on both breeds and loci level and by mean of unweighted pair group method with arithmetic mean and structure program, phylogenetic tree and population structure were tested. Results: A total of 108 distinct alleles (1%) were observed across the fourteen breeds, with 36 out of the 108 alleles (33.2%) being unique to only one breed. Genetic parameters were measured per the 14 breeds and the 9 loci. Medium to high heterozygosity was reported with high effective numbers of alleles (Ne). Polymorphic information contents (PIC) of the screened loci was found to be highly polymorphic for eleven breeds; while 3 breeds were reported moderately polymorphic. Breeding coefficient ($F_{IS}$) ranged from -0.033 to 0.358, and the pair wise genetic differentiation ($F_{ST}$) ranged from 0.01 to 0.36 across the fourteen breeds; for the 9 loci observed and expected heterozygosity, and Ne were same as the breeds parameters, PIC of the screened loci reported 6 loci highly polymorphic and 3 loci to be medium polymorphic, and $F_{IS}$ ranged from -0.113 to 0.368. In addition, genetic distance estimate revealed a close genetic distance between Canada goose and Hortobagy goose breeds by 0.04, and the highest distance was between Taihu goose and Graylag goose (anser anser) breed by 0.54. Conclusion: Cluster analyses were made, and they revealed that goose breeds had hybridized frequently, resulting in a loss of genetic distinctiveness for some breeds.

Spatial and Temporal Genetic Diversity and Population Structure of Hemileia vastatrix from Peruvian Coffee Plantations

  • Quispe-Apaza, Cinthia;Mansilla-Samaniego, Roberto;Espejo-Joya, Rosa;Bernacchia, Giovanni;Yabar-Larios, Marisela;Lopez-Bonilla, Cesar
    • The Plant Pathology Journal
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    • 제37권3호
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    • pp.280-290
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    • 2021
  • Population genetic studies of Hemileia vastatrix have been conducted in order to describe the evolutionary dynamics of the pathogen and the disease epidemiology as consequence of changes in disease management and host distribution occurred in Peru after the 2013 epidemic. These analyses were performed by sequencing the internal transcribed spacers of the nuclear ribosomal DNA (rDNA-ITS) of H. vastatrix collected from two coffee growing areas in 2014 and 2018. H. vastatrix population showed high haplotype diversity (Hd = 0.9373 ± 0.0115) with a low nucleotide diversity (π = 0.00322 ± 0.00018). Likewise, AMOVA indicated that fungus population has behaved as a large population without structuring by geographical origin and sampling years (FST = 0.00180, P = 0.20053 and FST = 0.00241, P = 0.19693, respectively). Additionally, the haplotype network based on intraspecific phylogenetic analysis of H. vastatrix using Peruvian and NCBI sequences revealed that Peruvian ancestral haplotypes, which were maintained in time and space, would correspond to the reported sequences of the races II and XXII. This result suggests that no substantial changes have occurred through time in Peruvian Hemileia vastatrix population.

Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training

  • Kim, Minsun;Kim, Seung Kyum
    • The Korean Journal of Physiology and Pharmacology
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    • 제25권1호
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    • pp.1-14
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    • 2021
  • Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors for CVD. Recent studies have demonstrated that cardiac structure and function are genetically influenced, suggesting that understanding the genetic basis for cardiac structure and function could provide new insights into developing novel therapeutic targets for CVD. Regular exercise has long been considered a robust nontherapeutic method of treating or preventing CVD. However, recent studies also indicate that there is inter-individual variation in response to exercise. Nevertheless, the genetic basis for cardiac structure and function as well as their responses to exercise training have yet to be fully elucidated. Therefore, this review summarizes accumulated evidence supporting the genetic contribution to these traits, including findings from population-based studies and unbiased large genomic-scale studies in humans.

바이러스-메시 유전 알고리즘에 의한 퍼지 모델링 (The Fuzzy Modeling by Virus-messy Genetic Algorithm)

  • 최종일;이연우;주영훈;박진배
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2000년도 추계학술대회 학술발표 논문집
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    • pp.157-160
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    • 2000
  • This paper deals with the fuzzy modeling for the complex and uncertain system in which conventional and mathematical models may fail to give satisfactory results. mGA(messy Genetic Algorithm) has more effective and adaptive structure than sGA with respect to using changeable-length string and VEGA(Virus Evolution Genetic) Algorithm) can search the global and local optimal solution simultaneously with reverse transcription operator and transduction operator. Therefore in this paper, the optimal fuzzy model is obtained using Virus-messy Genetic Algorithm(Virus-mGA). In this method local information is exchanged in population so that population may sustain genetic divergence. To prove the surperioty of the proposed approach, we provide the numerical example.

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Genetic Diversity and Relationship in Soybean MDP (Mutant Diversity Pool) Revealed by TRAP and TE-TRAP Markers

  • Kim, Dong-Gun;Bae, Chang-Hyu;Kwon, Soon-Jae
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2019년도 춘계학술대회
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    • pp.32-32
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    • 2019
  • Mutation breeding is the useful tool to improve agronomic traits in various crop species. Soybean is most important crop and is rich in protein and oil contents. Despite of the importance as economic value and various genetic resource of soybean, there have been limited studies of genetic relationship among mutant resources through radiation breeding. In this study, the agronomical phenotype for selecting various genetic resources was evaluated in 528 soybean mutant lines. As a result, 210 soybean mutants with their original cultivars were selected with various traits. We named 210 selected lines as Mutant Diversity Pool (MDP). The genetic diversity and the relationship of the MDP were investigated using TRAP and TE-TRAP markers. In TRAP analysis, sixteen primer combination (PC)s were used and a total of 551 fragments were amplified. The highest (84.00%) and the lowest (32.35%) polymorphism levels were showed in PC MIR157B+Ga5 and B14G14B+Ga3, respectively. The mean of PIC values was 0.15 ranging from 0.07 in B14G14B+Sa12 to 0.23 in MIR157B+Sa4. Phylogenetic and population structure analysis indicated that the 210 MDP lines dispersed to four groups among the wild types and their mutants. The highest genetic diversity among populations was observed between lines Paldal and 523-7 (Fst=0.409), whereas the lowest genetic diversity was between population KAS360-22 and 94seori (Fst=0.065). AMOVA showed 11.583 (21.0%) and 43.532 (79.0%) variations in inter and intra mutant population, respectively. Overall, the genetic similarity of each intra mutant populations was closer than that of inter mutant population. A total of 408 fragments were amplified in the 210 MDP using twelve PCs of TE-TRAP markers that were obtained from a combination of three TIR sequence of transposable elements (MITE-stowaway; M-s, MITE-tourist; M-t, PONG). The highest (77.42%) and the lowest (56.00%) polymorphism levels were showed in PONG+Sa4 and PONG+Sa12, respectively. The mean of PIC values was 0.15 ranging from 0.09 in M-s+Sa4 and M-s+Ga5 to 0.21 in M-t+Ga5. AMOVA of M-s showed 2.209 (20%) and 8.957 (80%) variations in inter and intra mutant population, respectively. AMOVA of M-t showed 2.766 (18%) and 12.385 (82%) variations in inter and intra mutant population, respectively. AMOVA of PONG showed 3.151 (29%) and 7.646 (71%) variations in inter and intra mutant population, respectively. According to our study, the PONG had higher inter mutant population and lower intra mutant population. This mean was that for aspect of radiation sensitivity, M-s and M-t showed higher mobility than that of PONG. Our results suggest that the TRAP and the TE-TRAP markers may be useful for assessing the genetic diversity and relationship among soybean MDP and help to improve our knowledge of soybean mutation/radiation breeding.

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Optimization of a Composite Laminated Structure by Network-Based Genetic Algorithm

  • Park, Jung-Sun;Song, Seok-Bong
    • Journal of Mechanical Science and Technology
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    • 제16권8호
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    • pp.1033-1038
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    • 2002
  • Genetic alsorithm (GA) , compared to the gradient-based optimization, has advantages of convergence to a global optimized solution. The genetic algorithm requires so many number of analyses that may cause high computational cost for genetic search. This paper proposes a personal computer network programming based on TCP/IP protocol and client-server model using socket, to improve processing speed of the genetic algorithm for optimization of composite laminated structures. By distributed processing for the generated population, improvement in processing speed has been obtained. Consequently, usage of network-based genetic algorithm with the faster network communication speed will be a very valuable tool for the discrete optimization of large scale and complex structures requiring high computational cost.

동아시아 질경이 집단의 유전적 다양성과 집단구조 (Genetic Diversity and Population Structure in East Asian Populations of Plantago asiatica)

  • 허만규
    • 생명과학회지
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    • 제23권6호
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    • pp.728-735
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    • 2013
  • 질경이(Plantago asiatica)는 주로 동아시아에 분포하는 풍매화 식물이다. 전분 젤 전기영동으로 이 종의 18개 집단에 대한 알로자임 다양성과 집단구조를 평가하였다. 비록 질경이 집단은 작고 격리되어 있지만, 높은 유전적 다양성을 가지고 있었다. 평균 다형성을 나타내는 유전자좌위의 수는 57.1%였고, 대립유전자좌위당 유전자수는 2.07이였으며, 18개 집단에 대한 이형접합성은 0.201이였다. 풍매화, 혼합적 생식교배계, 큰 집단 크기, 집단 간 높은 유전자 이동, 다산의 특성이 집단 내 유전적 다양성을 설명할 수 있다. 유전적 다양성은 위도와 관련이 있었는데 질경이 집단은 북위 $35^{\circ}3^{\prime}$를 초과하면 유전적 다양성은 현저하게 감소하였다. 반면에 유전적 다양성에 대한 경도 구배는 나타나지 않았다.

Analysis of genetic differentiation and population structure of the Korean-peninsula-endemic genus, Semisulcospira, using mitochondrial markers

  • Eun-Mi Kim;Yeon Jung Park;Hye Min Lee;Eun Soo Noh;Jung-Ha Kang;Bo-Hye Nam;Young-Ok Kim;Tae-Jin Choi
    • Fisheries and Aquatic Sciences
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    • 제25권12호
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    • pp.601-618
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    • 2022
  • The genus Semisulcospira is an economically and ecologically valuable freshwater resource. Among the species, Semisulcospira coreana, Semisulcospira forticosta and Semisulcospira tegulata are endemic to the Korean peninsula and Semisulcospira gottschei is widespread in Asia. Therefore, maintenance and conservation of wild populations of these snails are important. We investigated the genetic diversity and population structure of Semisulcospira based on the mitochondrial cytochrome c oxidase subunit I (COI), NADH dehydrogenase subunit 4 (ND4), and combined mitochondrial DNA (COI + ND4) sequences. All four species and various genetic makers showed a high level of haplotype diversity and a low level of nucleotide diversity. In addition, Fu's Fs and Tajima's D neutrality tests were performed to assess the variation in size among populations. Neutrality tests of the four species yielded negative Fu's Fs and Tajima's D values, except for populations with one haplotype. The minimum spanning network indicated a common haplotype for populations of S. coreana, S. tegulata and S. gottschei, whereas S. forticosta had a rare haplotype. Also, genetic differences and gene flows between populations were assessed by analysis of molecular variance and using the pairwise fixation index. Our findings provided insight into the degree of preservation of the species' genetic diversity and could be utilized to enhance the management of endemic species.