• Title/Summary/Keyword: Population dynamic

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Optimal Design for Marker-assisted Gene Pyramiding in Cross Population

  • Xu, L.Y.;Zhao, F.P.;Sheng, X.H.;Ren, H.X.;Zhang, L.;Wei, C.H.;Du, L.X.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.6
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    • pp.772-784
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    • 2012
  • Marker-assisted gene pyramiding aims to produce individuals with superior economic traits according to the optimal breeding scheme which involves selecting a series of favorite target alleles after cross of base populations and pyramiding them into a single genotype. Inspired by the science of evolutionary computation, we used the metaphor of hill-climbing to model the dynamic behavior of gene pyramiding. In consideration of the traditional cross program of animals along with the features of animal segregating populations, four types of cross programs and two types of selection strategies for gene pyramiding are performed from a practical perspective. Two population cross for pyramiding two genes (denoted II), three population cascading cross for pyramiding three genes(denoted III), four population symmetry (denoted IIII-S) and cascading cross for pyramiding four genes (denoted IIII-C), and various schemes (denoted cross program-A-E) are designed for each cross program given different levels of initial favorite allele frequencies, base population sizes and trait heritabilities. The process of gene pyramiding breeding for various schemes are simulated and compared based on the population hamming distance, average superior genotype frequencies and average phenotypic values. By simulation, the results show that the larger base population size and the higher the initial favorite allele frequency the higher the efficiency of gene pyramiding. Parents cross order is shown to be the most important factor in a cascading cross, but has no significant influence on the symmetric cross. The results also show that genotypic selection strategy is superior to phenotypic selection in accelerating gene pyramiding. Moreover, the method and corresponding software was used to compare different cross schemes and selection strategies.

Detection of damage in truss structures using Simplified Dolphin Echolocation algorithm based on modal data

  • Kaveh, Ali;Vaez, Seyed Rohollah Hoseini;Hosseini, Pedram;Fallah, Narges
    • Smart Structures and Systems
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    • v.18 no.5
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    • pp.983-1004
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    • 2016
  • Nowadays, there are two classes of methods for damage detection in structures consisting of static and dynamic. The dynamic methods are based on studying the changes in structure's dynamic characteristics. The theoretical basis of this method is that damage causes changes in dynamic characteristics of structures. The dynamic methods are divided into two categories: signal based and modal based. The modal based methods utilize the modal properties consisting of natural frequencies, modal damping and mode shapes. As the modal properties are sensitive to changes in the structure, these can be used for detecting the damages. In this study, using dynamic method and modal based approach (natural frequencies and mode shapes), the objective function is formulated. Then, detection of damages of truss structures is addressed by using Simplified Dolphin Echolocation algorithm and solving inverse optimization problem. Many scenarios are used to simulate the damages. To demonstrate the ability of the algorithm, different truss structures with several multiple elements scenarios are tested using a few runs. The influence of the two different levels of noise in the modal data for these scenarios is also considered. The last example of this article is investigated using a different mutation. This mutation obtains the exact answer with fewer loops and population by limited computational effort.

A Study on the Establishment of Spatiotemporal Scope for Dynamic Congestion Pricing (동적 혼잡통행료 적용을 위한 시공간 범위 설정에 관한 연구)

  • KIM, Min-Jeong;KIM, Hoe-Kyoung
    • Journal of the Korean Association of Geographic Information Studies
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    • v.25 no.2
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    • pp.100-109
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    • 2022
  • Large-scale urban concentration of population and vehicles due to economic growth in Korea has been causing serious urban transport problems. Although the collection of congestion pricing has been evaluated as the most effective transportation policy to alleviate traffic demand, its effectiveness is very limited as it was just executed around congested points or along main arterial roads. This study derived dynamic congestion zones with the average travel speed of 206 traffic analysis zones in Busan Metropolitan City to propose a dynamic congestion pricing collection system by employing Space-Time Cube Analysis and Emerging Hot Spot Analysis. As a result, dynamic hot spots were formed from 7h to 24h and particularly, traffic congestion was severely deteriorated from 18h to 20h around Seomyeon and Gwangbok-dong. Therefore, it is expected that the effect of dynamic congestion pricing will be maximized in managing traffic demand in the city center.

Demographic review of aesthetic surgery for patients with facial palsy

  • Min Young Lee;Yun Jung Kim;Young Seok Kim;Tai Suk Roh;In Sik Yun
    • Archives of Craniofacial Surgery
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    • v.25 no.1
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    • pp.22-26
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    • 2024
  • Background: This study analyzed the demographic characteristics of patients with facial palsy who were treated using either dynamic or static procedures. This study aimed to compare the frequency of procedure implementation and age distribution between the two groups. Methods: This study retrospectively analyzed the medical records of patients treated for facial palsy at a single institution from 2014 to 2022. Among cases included in our study, dynamic procedures involved cross-facial nerve graft and latissimus dorsi or gracilis muscle flap transfer. Static procedures included gold weight insertion, canthopexy, browlift, and thread lift/static slings. Results: Among the 31 patients included in our study, eight (25.8%) incorporated dynamic techniques, and the average age of patients was 44.75 years (range, 24-68 years) with a male to female ratio of 1:4. The remaining 23 patients (74.2%) underwent a static procedure, of which the average age was 59.17 years (range, 23-81 years) which was statistically significantly higher than the average age of 44.75 of dynamic patients (p= 0.013). Regarding the timing of treatment after diagnosis, no patient underwent dynamic procedures more than 20 years after initial diagnosis. A greater diversity in the timing of treatment was observed in the static group. All patients who underwent dynamic procedures were treated using static procedures during the study period. Conclusion: Because aesthetics-based static techniques are typically quick outpatient procedures that can be performed under local anesthesia, our study shows that these are often preferred treatments for all age groups, especially for debilitated or older patients. Further research is required to investigate the long-term functional outcomes of these surgical techniques in a wider population of patients.

An Optimal Strategy for Private Life Annuity by Utilizing AEW (AEW를 활용한 개인종신연금의 최적화 전략)

  • Yang, Jae-Hwan;Yuh, Yoon-Kyung
    • IE interfaces
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    • v.24 no.3
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    • pp.173-186
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    • 2011
  • In this paper, we evaluate life annuity plans for Korean pre-retired single and married couple participating Korea National Pension (KNP) and find optimal life annuity strategy by using utility-based measurements called AEW (Annuity Equivalent Wealth). Specifically, we extend a previous study to obtain a detailed optimal combination of annuitizing age and wealth in terms of percentage of net wealth at the time of retirement. A nonlinear optimization model is formulated with the objective of maximizing utility on consumption and bequest, and the dynamic programming (DP) technique is used to solve this problem. We find that there exist consistent patterns in optimal combinations of annuitizing age and wealth. Also, for all cases the optimal combination is significantly better than several other combinations. The results indicate that using the optimal approach can be beneficial to practitioners in insurance industry and prospective purchasers of life annuity. We conclude the paper with some discussions and suggestions.

Finding Policy Leverages with Analysis of Dynamic Growth Behaviors of Cyberspace and Electronic Commerce (전자공간과 전자상거래 성장의 동태성 분석을 통한 Policy Leverage 탐색)

  • 하원규;김도훈;문태훈;최남희;홍민기
    • Korean System Dynamics Review
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    • v.1 no.1
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    • pp.29-56
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    • 2000
  • During the past few years, cyberspace and electronic commerce has been expanding throughout the world rapidly. The purpose of this paper is to find out policy leverages for boosting up cyberspace and electronic commerce using system dynamics simulation modeling approach. The system dynamics simulation model developed in this paper allows analysis of both the effect of factors on dynamic growth pattern of cyberspace as well as the effect of time delay in information processing, money transfer and delivery on model behavior. Finding of this study is that capacity of information infrastructure and size of cyberspace population are key factors of cyberspace growth. Also, reducing time delay in information flow, money flow, and delivery flow is an important policy leverages for growth of electronic commerce.

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A STUDY ON CANCER CELL INVASION WITH A THREE-DIMENSIONAL DYNAMIC MULTI-PHYSICS MODEL (3차원 동적 다중물리 모델 기반 암세포 증식과정 예측기술 개발)

  • Song, J.;Zhang, L.;Kim, D.
    • 한국전산유체공학회:학술대회논문집
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    • 2010.05a
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    • pp.556-561
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    • 2010
  • This paper proposes a three-dimensional haptotaxis model to simulate the migration of the population of cancer cells. The invasion of the cancer cells relates with the hapto- and the effect of the energy between cells and (ECM). The diffuse interface model is employed, which incorporates haptotaxis mechanism and interface energies. The semi-implicit Fourier spectral scheme is adopted for efficient complications. The simulation results reveal rich dynamics of cancer cells migration.

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Discovery of highly dynamic and recurrent jets in a polar coronal hole observed by Hinode/SOT

  • Cho, Il-Hyun;Moon, Yong-Jae;Cho, Kyung-Suk
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.50.4-50.4
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    • 2019
  • We detect a new population of chromospheric jets in a polar coronal hole observed by Hinode/SOT. The propagating speed of the jets ranges in 30 - 490 km/s whose duration time is 3 - 52 s. The recurrent rate is approximately 3/min for a give segment of 1 arc-second horizontal interval. These jets are seemed to be more transient and faster than type II spicules at chromosphere, while the properties are compatible with the network jets seen in emission lines of transition region. We will discuss the implication of these jets for a coronal heating.

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Genetic diversity of Forsythia ovata Nakai (Oleaceae) based on inter-simple sequence repeats (ISSR) (ISSR 자료에 기초한 만리화(물푸레나무과)의 유전적 다양성)

  • Kim, Sang-Yong;Kim, Young-Dong;Kim, Jin-Seok;Yang, Byeong-Hoon;Kim, Sung-Hee;Lee, Byung-Chun
    • Korean Journal of Plant Taxonomy
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    • v.39 no.1
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    • pp.48-54
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    • 2009
  • We investigated the genetic diversity of an endemic rare species, Forsythia ovata Nakai by examining 93 ISSR amplicons in 84 individuals distributed among five populations. The overall percentage of polymorphic ISSR amplicons was 54.8% and mean number of amplicons per ISSR primer was 6.6. The amount of genetic diversity was relatively lower than other shrub species. The Mt. Seokbyeong and Mt. Seorak B populations had the highest level of genetic diversity. Although the Seokgae-jae population had the lowest level of genetic diversity, the population was genetically the most distinctive from the other populations. About 30.6% of the total variation was allocated between five populations, which was slightly higher than other shrub species. Such a pattern of genetic variation may have resulted from the limited distribution and small population sizes of F. ovata. The UPGMA dendrogram based on Nei's genetic distance showed some decisive geographic patterns. These results suggest that, in addition to the preservation of the natural stands, the conservation of larger number of populations with small number of individuals per population is more effective for the dynamic ex situ conservation and for maintaining the genetic diversity of F. ovata than smaller number of populations with large number of individuals.

Seismic demand estimation of RC frame buildings based on simplified and nonlinear dynamic analyses

  • Borzi, B.;Vona, M.;Masi, A.;Pinho, R.;Pola, D.
    • Earthquakes and Structures
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    • v.4 no.2
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    • pp.157-179
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    • 2013
  • Vulnerability studies on the existing building stock require that a large number of buildings is analyzed to obtain statistically significant evaluations of the seismic performance. Therefore, analytical evaluation methods need to be based on simplified methodologies of analysis which can afford the treatment of a large building population with a reasonable computational effort. Simplified Pushover-Based Earthquake Loss Assessment approach (SP-BELA), where a simplified methodology to identify the structural capacity of the building through the definition of a pushover curve is adopted, was developed on these bases. Main objective of the research work presented in this paper is to validate the simplified methodology implemented in SP-BELA against the results of more sophisticated nonlinear dynamic analyses (NLDAs). The comparison is performed for RC buildings designed only to vertical loads, representative of the "as built" in Italy and in Mediterranean countries with a building stock very similar to the Italian one. In NLDAs the non linear and degrading behaviour, typical of the structures under consideration when subjected to high seismic loads, is evaluated using models able to capture, with adequate accuracy, the non linear behaviour of RC structural elements taking into account stiffness degradation, strength deterioration, and pinching effect. Results show when simplified analyses are in good agreement with NLDAs. As a consequence, unsatisfactory results from simplified analysis are pointed out to address their current applicability limits.