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Fine needle aspiration cytology of enlarged lymph nodes in children and adolescents (소아 및 청소년에 있어서 림프절 종대에 대한 미세침 흡인 세포검사법)

  • Lee, Seung Min;Oh, Yoon Jung;Jun, Yong Hoon;Hong, Young Jin;Son, Byong Kwan;Kim, Soon Ki;Han, Jee Young;Chu, Young Chae
    • Clinical and Experimental Pediatrics
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    • v.49 no.2
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    • pp.167-172
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    • 2006
  • Purpose : Palpable lymph nodes are common in the pediatric population, and most of them are either inflammatory or congenital. As the diagnostic evaluation, fine needle aspiration cytology (FNAC) is known to be more convenient and economical than tissue biopsy. We evaluated the usefulness of FNAC in children and adolescents. Methods : Four hundred and thirteen FNAC samples(M : F=1 : 1.15) were retrospectively analyzed in patients who were brought to Inha University Hospital, from August 1999 to August 2004. Results : The most common age group was 16-20 years of age(N=148, 35.8 percent). The cervical area was the most frequently involved site(N=310, 75 percent). Non-specific lymphadenitis was the most common(N=227, 54.9 percent), followed by the benign neoplasm(N=59, 14.2 percent). Malignant tumors were 18 cases(4.3 percent), and congenital diseases were found in 10 cases(2.4 percent). In inflammatory lesions, tuberculous lymphadenitis(N=22, 5.3 percent) was the most common with a histologic sensitivity of 90.9 percent. The peripheral blood and serologic studies were non-specific. Fifty nine percent(N=244) of lymphadenitis improved without specific management. Antibiotics were prescribed in 15.2 percent of lymphadenitis and lymphadenectomy was performed in 12.6 percent. Conclusion : Most of the enlarged lymph nodes in children and adolescents were benign. These results show FNAC is a safe, rapid and reliable diagnostic procedure for the appropriate differential diagnosis of enlarged lymph nodes in children and adolescents.

Birth weight for gestational age patterns by sex, plurality, and parity in Korean population (한국의 성별, 태아수별, 출산수별 임신주수에 따른 출생체중)

  • Lee, Jung Ju
    • Clinical and Experimental Pediatrics
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    • v.50 no.8
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    • pp.732-739
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    • 2007
  • Purpose : A universal standard of the birth weight for gestational age cannot be made since birth weight distribution varies with races, nations and eras. This report aims to establish the birth weight for gestational age patterns by sex, plurality, and parity, specific for Korean live births. Methods : The national birth certificate data of all live births in Korea from January 2000 to December 2004 were used: for live births with gestational age 24 weeks to 42 weeks (n=2,585,5160), mean birth weight, standard deviation and 10th, 25th, 75th and 90th percentile values were obtained for each gestational age group by one week increment. To establish final standard values of Korean birth weight distribution by gestational age, the finite mixture model to eliminated erroneous birth weights was used for respective gestational age. Same as above method the birth weight for gestational age standard by sex, plurality, and parity were completed. Results : The male newborns are more heavier than female during the entire gestational age. The singletons are more heavier than twin during the entire gestational age. The para 2 are more heavier than the para 1 during the entire gestational age. Korean standard was more heavier in 10th and 50th percentile than Lubchenco's standard. Alexander's standard was more heavier in 50th and 90th percentile than Korean standard. Conclusion : These birth weight for gestational age patterns by sex, plurality, and parity are similar to the other standards. I hope that for Korean infants, this curve will help clinicians in defining and managing the large for gestational age infants and also for infants with intrauterine growth retardation.

The Analysis and Strengthening Method of Export Competitive Power of Medical Device Industry - With Respect to Medical Device Industry in Gangwon Area (의료기기산업의 수출경쟁력 분석 및 강화방안 -강원지역 의료기기산업을 중심으로-)

  • Lee, Kang-Bin
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.45
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    • pp.191-238
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    • 2010
  • The purpose of this paper is to make research on the trend of the worldwide medical device market, the trend of the medical device market in the major foreign countries, the present status of the medical device industry in Korea and Gangwon area, the present status of export competitive power and the SWOT analysis of competitive power of the medical device industry in Gangwon area, and the strengthening methods of export competitive power of the medical device industry in Gangwon area. As the research method, the questionaire for the strengthening of export competitive power of the medical device industry in Gangwon area was carried out from August 13 to Otober 22, 2009. The worldwide medical device market in 2008 is estimated at USD 210.2 billion, with the United States being the largest market, followed closely by Japan and Western Europe. In 2006, the worldwide export amount of medical devices recorded USD 121.1 billion and the worldwide import amount of medical devices recorded USD 126.3 billion. As of the end of 2008, the number of Korea's medical device manufacturers expanded to 1,726. The production amount of Korea's medical device industry in 2008 recorded 2,525 billion won, and the domestic market volume of medical devices in 2008 recorded 3,618 billion won. Korea's export amount of medical devices in 2008 recorded USD 1,132 million and recorded a 9.67% growth compared to the previous year, and the import amount of medical devices recorded USD 2,123 million and recorded a 1.43% reduction compared to the previous year. As of the end of 2008, the number of Gangwon area's medical device manufacturers expanded to 81. The production amount of Gangwon area's medical industry in 2008 recorded 380 billion won, and Gangwon area's export amount of medical devices recorded USD 269 million and recorded a 0.25% reduction compared to the previous year, and the import amount of medical devices recorded USD 3 million and recorded a 39.63% reduction compared to the previous year. According to the result analysis of the questionaire for the strengthening of export competitive power of medical device industry in Gangwon area(August 13~October 22, 2009), the competing country of the export medical device is the United States being the highest ranking. Comparing to the collective competitive power level 100 of the competing country, the collective competitive level of the export medical device is 60 below and 70-80 below being the highest ranking. Comparing to the quality level 100 of the United States, EU and Japan, the quality level of the export medical device is 80-90 below being the highest ranking. Comparing to the design level 100 of the United States, EU and Japan, the design level of the export medical device is 90-100 below being the highest ranking. Comparing to the technology level 100 of the United States, EU and Japan, the technology level of the export medical device is 80-90 below being the highest ranking. According to the SWOT analysis of competitive power of medical device industry in Gangwon area, the strength is the abundant expert manpower of the medical device in Wonju area. The weakness is the fragility of the brand recognition of the medical device industry. The opportunity is the demand increase of the new medical device owing to the advanced age of population. The threat is the difficulty of entry into overseas market owing to the request of the new specification certification of the medical device. In order to strengthen the export competitive power of the medical device industry in Gangwon area, the following measures should be taken by the government, local self-government body, related organization and medical device industry : the development of new technology and design, the enhancement of brand recognition. the acquisition of the foreign specification certification, the building of overseas distribution channel and after sales service channel, the positive participation in overseas medical device exhibition and opening of medical device exhibition, the training of expert manpower, the strengthening of overseas marketing, and the application of FTA and the establishment of counter measures against FTA. In conclusion, the medical device industry in Gangwon area has the difficulty in the entry into the overseas market owing to the shortage of overseas marketing capability. Therefore, the government and local self-government body should make the intensive and systematical support for overseas marketing of the medical device industry. For the support of overseas marketing, the government and local self-government body should provide positively the support of expenses for the acquisition of foreign specification certification, the support of participation in the overseas medical device exhibition, the despatch of market development mission, the increase of the support amount for R&D investment fund, and the training of expert manpower of medical devices.

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A Study on Establishment of Technical Guideline of the Installation and Operation for the Biogas Utilization of Power generation and Stream - Results of the Precision Monitoring (바이오가스 이용 기술지침 마련을 위한 연구(II) - 정밀모니터링 결과 중심으로)

  • Moon, HeeSung;Bae, Jisu;Park, Hoyeun;Jeon, Taewan;Lee, Younggi;Lee, Dongjin
    • Journal of the Korea Organic Resources Recycling Association
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    • v.26 no.1
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    • pp.65-78
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    • 2018
  • According to the in social aspects such as population growth, urbanization and industrialization, development of livestock industry by meat consumption, amount of organic wastes (containing sewage sludge and food waste, animal manure, etc) has been increased annually in South Korea. Precise monitoring of 11 organic wastes biogas facilities were conducted. The organic decomposition rate of organic wastewater was 68.2 % for food wastes, 66.8 % for animal manure and 46.2 % for sewage sludge and 58.8 % for total organic wastes. As a result of analyzing the biogas characteristics before and after the pretreatment, the total average of the whole facility was measured to be 560 ppm using iron salts and desulfurization, and decreased to 40 ppm when the reduction efficiency was above 90 %. Particularly, when iron salt is injected into the digester, the treatment efficiency is about 93 %, and the average is reduced to 150 ppm. In the case of dehumidification, the absolute humidity and the relative humidity were analyzed. The dew point temperature of the facility where the dehumidification facility was well maintained as $14^{\circ}C$, the absolute humidity was $12.6g/m^3$, and the relative humidity was 35 %. Therefore, it is necessary to compensate for the disadvantages of biogasification facilities of organic waste resources and optimize utilization of biogas and improve operation of facilities. This study was conducted to optimize biogas utilization of type of organic waste(containing sewage sludge and food waste, animal manure) through precision monitoring.

The Relationship of Anxiety Symptoms and Depressive Symptoms to Glycemic Control in Diabetic Patients (당뇨병 환자에서 우울증상 및 불안증상과 혈당조절과의 연관성)

  • Jeon, Byung-Hee;Kim, Hyun-Woo;Kim, Hee-Jin;Lim, Myung-Ho;Lee, Seok-Bum;Paik, Ki-Chung;Lee, Kyung-Kyu
    • Korean Journal of Psychosomatic Medicine
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    • v.16 no.2
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    • pp.95-102
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    • 2008
  • Objectives : Diabetes patients suffer from severe stress in maintaining the diet therapy and exercise therapy as well as the disease itself, and this stress has bad effects on controlling the glucose level and causes high prevalence rate of depressive and anxiety disorders. These symptoms again have deleterious effects on blood glucose control. A lot of researches about the relationship between glycemic control and symptoms of depression and anxiety and about the positive effects of the treatments of depression and anxiety disorder on glycemic control in diabetic patients are being performed. In Korea, the research regarding the relationship between glycemic control and depression and anxiety symptoms are seldom performed. In this study, we tried to find out the correlation between the glycemic control and depressive symptom and anxiety symptom. Methods : The study included 65 patients(male 34, female 31) with Diabetes in outpatient clinic of the Department of Endocrinology in Dankook University Hospital. We used the HbA1c levels to check glycemic control through blood sample analysis and used Beck Depression Inventory(BDI) and Beck Anxiety Inventory(BAI). Results : Among the 65 Diabetes patients, 21(32.30%) had mild depressive symptoms, and 6(9.23%) had moderate or severe depressive symptoms. The relation of HbA1c and BDI was not statistically significant, but was significant between HBA1c and BAI, (R=0.567, P<0.001). In the linear regression analysis, BAI had an effect on HbA1c($\beta=0.533$, T=5.012, P=0.00), but BDI, diabetes complications, diabetic morbid period and BMI had no effect on HbA1C. The relationship between HbA1c and BDI was not statistically significant, but the relationship between HbA1c and BAI was statistically significant(R=0.254, P<0.001). Conclusions : In this study, the rates of diabetic patients with depressive symptoms were higher, but those with anxiety symptoms were not higher than the general population. We could not find out significant relationship between depressive symptom and glycemic control, but found the significant relationship between the anxiety symptom and glycemic control in diabetic patients.

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Quaternary Geology of the Conjunction Area of the Yeongsan and Sampo rivers (영산강 하류와 삼포강 합류부 일대 제4기 지질 연구)

  • Kim, Ju-Yong;Yang, Dong-Yoon;Hong, Sei-Sun;Nahm, Wook-Hyun;Lee, Heon-Jong;Lee, Jin-Young;Kim, Jin-Kwan;Oh, Keun-Chang
    • The Korean Journal of Quaternary Research
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    • v.19 no.1
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    • pp.1-17
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    • 2005
  • This study aims to study the distribution and formation age of Quaternary deposits in the downstream of Yeongsan Estuarine River, encompassing Muan, Illo and Donggang counties. For this purpose the authors examine several borehole data, and step trench survey for excellent profiles was studied in connection with grain size population and magnetic susceptibility. As a result, it is interpreted that the coastal plain of the Yeongsan River was formed by sea level rise after Last Glacial Maximum(LGM). The fore edge/escarpment of coastal terraces distributed 7-10 m asl is assumed to be formed during the last glacial period, while the coastal terraces distributed above 7-10m asl formed during MIS 5a. In addition, the fore edge/escarpment of coastal terraces distributed above 15 m asl is presumed to be have been formed during the stadial of last interglacial period, while the formation age of coastal terraces distributed above 15m(asl) is assumed to be MIS 5e. This formation age can be estimated by the coastal terrace ages of the southeastern coast of Korean Peninsula. The characteristics of Quaternary deposits linked to paleolithic culture will eventually lead to the reconstruction of ecosystem environment of paleolithic peoples.

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Inheritance and Cross Resistance of Acequinocyl Resistance in Twospotted Spider Mite, Tetranychus urticae (Acequinocyl 저항성 점박이응애의 유전과 교차저항성)

  • Kim, Eun-Hee;Yang, Jeong-Oh;Yoon, Chang-Mann;Ahn, Ki-Su;Kim, Gil-Hah
    • The Korean Journal of Pesticide Science
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    • v.11 no.2
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    • pp.125-130
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    • 2007
  • The development of resistance to acequinocyl was found in the population of the twospotted spider mite, Tetranychus urticae, collected from rose greenhouses in Gimhae, Gyeongnam province in January 2001. This pest is reared on 5 years treated with acequinocyl (over 200 times), and increased 87.8 folds in resistance as compared to susceptible strain (S). Inheritance of acequinocyl resistant strain (R) and cross resistance of this strain to 8 acaricides against T. urticae adults and eggs was investigated. There were differences of susceptibility in the acequinocyl concentration-mortality relationships in $F_1$ progenies obtained from reciprocal cross with the S and R strain ($S(female){\times}R(male)$, $R(female){\times}S(male)$). Degrees of dominance were -0.75, -0.57 in $F_1$ progenies of adult and egg of $S(female){\times}R(male)$. Inheritance in $F_1$ progenies of $S(female){\times}R(male)$ was incomplete recessive. Degree of dominance were 0.81, 0.45 in $F_1$ progenies of adult and egg of $R(female){\times}S(male)$, respectively. These results suggest that inheritance of acequinocyl resistance is controlled by a complete dominance. The R strain exhibited cross resistance of 1.1 and 0.9 fold to amitraz, bifenazate, and negatively correlated cross resistance of 0.08 fold to emamectin benzoate in adult females. The R strain showed cross resistance of 37.7, 14.0, and 26.2 fold to amitraz, milbemectin and spriodiclofen in eggs, respectively. Particularly it showed high levels of cross-resistance to pyridaben with 6538.3 fold. These chemicals showed negatively correlated cross-resistance exhibited 0.4, 0.3, and 0.2 fold to ahamectin, bifenazate, and emamectin benzoate in eggs.

A Study on the Characteristic of Pollutants of Water Quality and Sediments in Gul-po Stream Basin (굴포천 유역 내 수질 및 퇴적물의 오염물질 특성 파악에 관한 연구)

  • Ahn, Tae-Woong;Jung, Jae-Hoon;Kim, Tae-Hoon;Kim, Sea-Won;Choi, I-Song;Oh, Jong-Min
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.7
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    • pp.495-503
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    • 2012
  • The water quality of Gul-po Stream, the subject of this study, has been deteriorating because of the inflow of domestic sewage and the industrial wastewater due to industrialization and the problems relating to the structure of river including slow flow rate and the covering of river. In particular, the domestic sewage from small-medium sized factories by the river and large-scale industrial complex by the upper and middle streams of the river, and the domestic sewage from increasing population due to the regional development are the main pollution sources. Thus, this study aims to survey the water quality and the sediment affecting Gul-po Stream; monitor the state of pollution in water body; assess the yield of sediment and investigate the water quality of river and the problems arising from sediment; and then suggest reasonable ways to improve the situation. The findings from surveying pollution load shows the discharge increases up to average 72.8 times from the upper stream to the downstream of Gul-po Stream, and pollution load increases up to: SS 111 times, BOD 150 times, COD 145 times, the nutrient T-N 222 times and T-P 312 times on an average basis. As for the pollution concentration range, ignition loss is 1.29~12.43%; COD is 4,015~37,547 kg/day; T-N and T-P 94.8~352.5 kg/day and 81.8~372.3 kg/day, respectively. As for the releasing rate of sediment, T-N is -14.46~$156.61mg/m^2/day$; T-P is -11.53~$26.10mg/m^2/day$, indicating the likelihood of internal contamination due to the elution of sediment. This study is expected to be used as basic data to manage Gul-po Stream basin.

A Study on the Locational Decision Factors of Discount Stores : The Case of Cheonan (종합슈퍼마켓의 입지 결정 요인에 관한 연구 : 천안상권을 중심으로)

  • So, Jang-Hoon;Hwang, Hee-Joong
    • Journal of Distribution Science
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    • v.10 no.5
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    • pp.37-44
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    • 2012
  • In this paper, we investigate several factors that affect the locational decision of discount stores by using previous studies on the marketing area and the location of commercial facilities. We selected 21 primary variables that are expected to influence the decision of store location and, by factor analysis, grouped them into five underlying factors. Among these, the demographic factor, which shows the potential purchasing power level, had the greatest impact on the locational decision for the store. However, we found individual stores positioned according to unique locational characteristics in addition to the demographic factor. It means that we have to additionally consider if the vicinity of the market is based on any physical properties. Many previous studies proposed four decision factors for store location: the economic factor, the demographic factor, the land utilization factor, and traffic factor. However, the fivefold factors-our distinctive contribution-are more concrete and persuasive according to Korean reality. We show that location preference is based on the following criteria: (1) the area is densely populated, (2) houses stand close together, (3) residents have a high income level, (4) road traffic is developed and easy to access, and (5) public transportation is well developed. The demographic factor has the greatest impact on the location of a discount store. The number of households has a greater relevance to the demographic factor than does the individual consumer. Second, discount stores relatively prefer places where houses are located close together because such places offer easy access to the market. Third, a place whose residents have a high income level will be preferred, with its large cars and excellent traffic conditions. Fourth, a location would be highly rated if the roads around commercial facilities are well developed and their accessibility is good. Finally, discount stores must be located close to bus stops because female consumers, including housewives-the most important customers-evaluate stores based on distance. In this research, the variable of consumer attitude and preference was excluded, and the location factors of discount stores were analyzed according to a microscopic view through physical spatial data. In the future, the opening of new discount stores based on the five factors indicated above will require a comparatively shorter time from the first project feasibility analysis. In addition, the result of our study can be applied to the field of public policy for constructing and attracting large-scale distribution facilities.

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Health Related Lifestyle and Stress Among Inhabitants of a City in Korea (일부 도시지역 주민들의 일상생활습관과 스트레스와의 관련성)

  • 손철준;조영채
    • Korean Journal of Health Education and Promotion
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    • v.21 no.2
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    • pp.17-32
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    • 2004
  • The purpose of this study was to evaluate the patterns of stresses arising from various life styles and their related sociodemographic factors in urban residents. The subjects were recruited from the population of two ‘Dong’s (administrative blocks) representative of Daejeon city through stratified cluster random sampling during the period ranging from June I st to Aug. 31 st, 2003. Self-administered questionnaires, including items asking about subjects' sociodemographic characteristics, daily life styles, measurement of stresses by General Health Questionnaire (Goldberg, 1978), were delivered to 396 residents and their responses were analyzed with the following results. 1. Based on the discriminant scores of HPI, 46.7% of the subjects were found to have less than 4 points (poor life style), whereas 53.3% had points higher than 5 (good life style). Higher than 5 points were scored more frequently in females than in the male, in the age group of 40's - 60's than the 30's, in the group with spouse than without, in the group with both spouse and offsprings than without, and in the group owning a house than not. 2. Based on the degree of stress, 17.7% of the subjects were determined to be healthy, 74.5% were potentially under stress, and 7.8% were at higher risk of stress. The proportion of healthy individuals were significantly higher in the male, advanced aged group(40's and 60's), the group with higher education years( over highschool), with higher monthly income over two million Won, and with spouse, than their respective counterparts. On the other hand the proportion of the individuals potentially under stress and at higher risk of stress was significantly higher in the female, in the age group of 30's and over 60's, in the group with academic career lower than middle school, with monthly income lower than two million Won, and without spouse. 3. Based on the relation of HPI with degree of stresses, subjects with HPI scores lower than 4 had increased rate of falling into the groups under potential stress and at higher risk of stress, while on the other hand those with over 5 points were found to be healthy in light of stress. 4. Based on the specific relation of each item of HPI with degree of stress, the proportion of healthy individuals was higher in the groups who take appropriate hours of sleep(7-8hours), who take breakfasts everyday, who take physical exercises everyday, who don't smoke, who don't drink alcohol, who take snacks everyday, who are overweight and obese, whereas the proportion of the group under potential stress and at higher risk of stress was higher in their comparable counterparts. 5. The relation of mean scores of HPI with stress scores in both male and female subjects showed negative correlation that the higher HPI scores, the lower stress scores. 6. Multivariate regression analysis to reveal the factors influencing the stress of the subjects showed that for men the significant factors were age, education, presence of job or not, exercise, subjective health status, with the explanatory power of 26.3%. For women, they included educational years, presence of spouse or not, job, owning a house or not, sleeping hours, drinking habit, taking snacks, subjective health status, with the explanatory power of 31.8%. The above study results suggests that stresses of urban residents have significant correlation with daily life styles and this correlation is also remarkably distinguished by different age and sex.