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Feasibility, Safety, and Follow-up Angiographic Results of Endovascular Treatment for Non-Selected Ruptured Intracranial Aneurysms Under Local Anesthesia with Conscious Sedation

  • Kang, Jongsoo;Kang, Chul-Hoo;Roh, Jieun;Yeom, Jeong A;Shim, Dong-Hyun;Kim, Young Soo;Lee, Sang Won;Kim, Young-Soo;Park, Kee Hong;Kim, Chang-Hun;Kim, Soo-Kyoung;Choi, Nack-Cheon;Kwon, Oh-Young;Kang, Heeyoung;Baik, Seung Kug
    • Journal of Neurocritical Care
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    • v.11 no.2
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    • pp.93-101
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    • 2018
  • Background: At most centers, general anesthesia (GA) has been preferred for endovascular treatment (EVT) of ruptured intracranial aneurysms (RIAs). In this study, we analyzed procedural results, clinical outcomes, and follow-up angiographic findings for patients undergoing EVT for RIA under local anesthesia (LA) with conscious sedation (CS). Methods: We retrospectively evaluated 308 consecutive patients who underwent EVT for RIAs at a single institution between June 2009 and February 2017. EVT under LA with CS was considered for all patients with aneurysmal subarachnoid hemorrhage, regardless of Hunt and Hess (HH) scale score. Results: EVT was performed for 320 aneurysms in 308 patients with subarachnoid hemorrhages. The mean patient age was $55.5{\pm}12.6$ years. Moderate (III) and poor (IV, V) HH grades were observed in 75 (24.4%) and 77 patients (25%), respectively. Complete occlusion immediately after EVT was achieved for 270 (84.4%) of 320 aneurysms. Thromboembolic complications and intraprocedural ruptures occurred in 25 (7.8%) and 14 cases (4.3%), respectively. The morbidity rate at discharge (as defined by a modified Rankin scale score of 3 or greater) was 27.3% (84/308), while the mortality rate was 11.7% (36/308). Follow-up angiographic results were available for 210 (68.1%) of 308 patients. Recanalization was observed in 64 (29.3%) of 218 aneurysms in 210 patients. Conclusion: Based on our experience, EVT for RIAs under LA with CS was feasible, regardless of the clinical grade of the subarachnoid hemorrhage. Complication rates and follow-up angiographic results were also comparable to those observed when GA was used to perform the procedure.

A Study on Technology Evaluation Models and Evaluation Indicators focusing on the Fields of Marine and Fishery (기술력 평가모형 및 평가지표에 대한 연구: 해양수산업을 중심으로)

  • Kim, Min-Seung;Jang, Yong-Ju;Lee, Chan-Ho;Choi, Ji-Hye;Lee, Jeong-Hee;Ahn, Min-Ho;Sung, Tae-Eung
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.90-102
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    • 2021
  • Technology evaluation is to assess the ability of technology commercialization entities to generate profits by using the subject technology, and domestic technology evaluation agencies have established and implemented their own evaluation systems. In particular, the recently developed technology evaluation model in the fields of marine and fishery does not sufficiently reflect the poor environment for technology development compared to other industries, so it does not pass the level of T4 rating, which is considered appropriate for investment. This is recognized as a challenge that occurs when the common evaluation indicators and evaluation scales used in other industries, and when the scoring system for T1 to T10 grading is similarly or identically utilized. Therefore, through this study, we intend to secure the appropriateness and reliability of the results of the comprehensive rating calculation by developing technology evaluation models and indicators that well explain the nine marine and fisheries industry classification systems. Based on KED and technology evaluation case data, AHP-based index weighting and Monte Carlo simulation-based rating system are applied and the results of case studies are verified. Through the proposed model, we aim to enhance the usability of R&D and commercialization support programs based on fast, convenient and objective evaluation results by applying to upcoming technology evaluation cases.

The Qualitative Study on the Counseling Psychology Major Recognition of University Students (대학생들의 상담심리학 전공 인식에 관한 질적 연구)

  • Park, Jong-Hwan;Kim, Hyun-Sook
    • The Journal of the Korea Contents Association
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    • v.21 no.2
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    • pp.406-420
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    • 2021
  • This study used Glaser's grounded theory method for the recognition of college students' majors in counseling psychology. Among the 3rd and 4th grade students majoring in counseling psychology, 19 students participated in the study, focusing on them for 5 months and collecting data through individual interviews. As a result of analyzing the data, 103 concepts, 26 subcategories, 9 upper categories, and 1 core category were derived. As a result of the study, first, the participants wanted to relieve the burden of people's hearts and had the hope of becoming a healer. Second, among the participants, in terms of their personality and aptitude for their major field, they perceived it as joy and satisfaction, such as 'It fits well with the major,' 'I made a good choice,' and 'It became a turning point in life.' However, they also recognized the incompatibility of the major, such as disharmony of aptitude, burden of the role of counselor, and rejection of major. Third, although participants showed usefulness in their major learning, their perception of the career path in their major was acting as anxiety and conflict, but their concerns and conflicts resulted in financial difficulties, poor job conditions, and emotional exhaustion caused by long-term study. The burden of job, fear of counseling job, limit of undergraduate graduation, uncertainty of career, etc. acted as an obstacle in choosing a major career. Fourth, as a result of analyzing the interview data of the participants, a core category called' understanding and growth and the will of the counselor to realize the dream' was derived. In conclusion, the participant's perception of their major is the change and growth of themselves, the formation of a healthy relationship with others, and satisfaction with the suitability of their major and their aptitudes. It turned out to have a lasting will to do.

A Study on the Educational Gap between Regions according to the Manpower Allocation under the 「School Library Promotion Act」 (「학교도서관진흥법」 규정 인력 배치에 따른 지역 간 교육격차에 관한 연구)

  • Bong-Suk Kang
    • Journal of the Korean Society for Library and Information Science
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    • v.57 no.3
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    • pp.231-248
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    • 2023
  • The purpose of this study is to trigger a discussion on the educational gap between regions in school library resources. To this end, differences and correlations between other resources invested in the school library and output results were analyzed according to manpower allocation. There was a positive correlation between the number of books, the budget, the number of seats, the number of borrowed materials, and the number of students. It was analyzed that manpower allocation had a negative correlation with the number of subjects in which the ratio of students, the lowest grade in the achievement evaluation, was more than 1/2. As a result of examining the staffing according to the 「School Library Promotion Act」 by regional characteristics, it was found that the allocation rate was statistically significantly higher in the order of metropolitan area, and provincial unit. Depending on the regional characteristics, there were differences in net asset per household as well as differences in school library manpower assignment rates. In contrast, the large cities with relatively affluent school library manpower assignment rates were found to be higher. Therefore, based on the survey contents of this study, it was emphasized that the manpower stipulated in the 「School Library Promotion Act」 should be deployed as soon as possible even in relatively poor areas to bridge the educational gap between regions.

Rock Mass Stability of the Buddha Statue on a Rock Cliff using Fracture Characteristics and Geological Face-Mapping (마애불 암반의 단열특성과 지질맵핑을 이용한 안정성 해석)

  • Ihm, Myeong Hyeok
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.539-544
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    • 2023
  • The subject of this study is the Maae Buddha statue in granodiorite of the Mesozoic Cretaceous period, which is concerned about stability as a standing stone cultural property located in ◯◯-dong, Gyeongsangbuk-do. For stability analysis, three-dimensional face mapping, geological properties of joints, three-dimensional scanning, ultrasonic velocity, polarization microscopy, electron microscopy analysis and XRD analysis were performed. In addition, the safety factor of the Maaebul was calculated by analyzing the damage status investigation, stereographic projection analysis, rock classification, and limit equilibrium analysis. The types and scales of damage and possible collapse by section depend on the degree of weathering of the rock and the orientation and characteristics of the joints, but wedge-failure and toppling-failure are expected to be small-scale. The safety factor of Maaebul in dry and wet conditions is less than 1.2, so stability is concerned. The types of damage were mainly observed, such as exfoliation, cracking, granular decomposition, and vegetation growth. The Maaebul rock is granodiorite, and the surface discoloration materials are K, Fe, and Mg. The 4 sets of joints are developed, J1 is tensile joint and the others are shear joint. The uniaxial compressive strength estimated by ultrasonic exploration is 514kgf/cm2, which corresponds to most soft rocks and some weathered rocks. Rock classification(RMR) is estimated to be grade 5, very poor rock mass. These technique along with the existing methods of safety diagnosis of cultural properties are expected to be a reasonable tool for objective interpretation and stability review of stone cultural properties.

Evaluation of Teachers and Students on VR/AR Contents in the Science Digital Textbook: Focus on the Earth and Universe Area for the 8th Grade (과학 디지털 교과서 실감형 콘텐츠에 대한 교사와 학생의 평가 -중학교 2학년 지구와 우주 영역 콘텐츠를 중심으로-)

  • Hyun-Jung Cha;Seok-Hyun Ga;Hye-Gyoung Yoon
    • Journal of The Korean Association For Science Education
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    • v.43 no.2
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    • pp.59-72
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    • 2023
  • This study analyzed a group interview with six earth science teachers and eight middle school students to find out the evaluations and criteria they use to evaluate VR/AR contents (two virtual reality content and two augmented reality contents) in middle school science digital textbook. The study found the VR/AR contents were evaluated on four criteria as follows: VR/AR media characteristics; technical operation; user interface; and teaching-learning design. The evaluations can be summarized by each criterion. First, regarding VR/AR media characteristics, interesting features of VR/AR contents were considered relatively advantageous compared to other media like videos. However, its shortage of visual presence and inconvenience of using markers were mentioned as shortcomings. Second, in the technical operation criteria, teachers and students found the following conditions as technically challenging: failing to properly operate on a particular OS; huge volumes of contents in the application; and frequent freezing when using the application. Third, poor intuitiveness and lack of flexibility were found as negative aspects in user interface. Fourth, regarding teaching-learning design, the teachers evaluated whether the VR/AR contents delivered scientifically accurate information; whether they incorporated class goals set by teachers; and whether they can help students' inquiry. It turned out teachers gave negative feedbacks on VR/AR contents. The students evaluated VR/AR contents by assessing whether they help them with learning science but concluded they did not regard them necessary in science learning at school. Based on the findings, this study discusses which development direction VR/AR contents should take to be useful in teaching and learning science.

The effect of perineural injection therapy on neuropathic pain: a retrospective study

  • Haekyu Kim;Hyae Jin Kim;Young-Hoon Jung;Wangseok Do;Eun-Jung Kim
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.1
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    • pp.47-56
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    • 2024
  • Background: Among the various pain-related diseases that can be encountered at the clinic, there is a neuropathic pain that is difficult to treat. Numerous methods have been proposed to treat neuropathic pain, such as taking medication, nerve block with lidocaine, or neurolysis with alcohol or phenol. Recently, a method of perineural injection using dextrose instead of lidocaine was proposed. This study was designed to compare the effects of perineural injection therapy (PIT) with buffered 5% dextrose or 0.5% lidocaine on neuropathic pain. Methods: The data were collected from the database of pain clinic from August 1st, 2019 to December 31st, 2022 without any personal information. The inclusion criteria were patients diagnosed with postherpetic neuralgia (PHN), trigeminal neuralgia (TN), complex regional pain syndrome (CRPS), or peripheral neuropathy (PN), and patients who had undergone PIT with buffered 5% dextrose (Dextrose group) or 0.5% lidocaine (Lidocaine group) for pain control. The data of patients, namely sex, age, and pain score (numerical rating scale, NRS) were collected before PIT. The data of NRS, side effects, and satisfaction grade (excellent, good, fair, or poor) were collected one week after each of the four PIT, and two weeks after the last PIT. Results: Overall, 112 subjects were enrolled. The Dextrose group included 89 and Lidocaine group included 23 patients. Because the number of patients in the Lidocaine group was too small to allow statistical analysis, the trend in Lidocaine group was just observed in each disease. There were no significant side effects except for a few bruise cases on the site of injection in all groups. The NRS in most Dextrose groups except CRPS were reduced significantly; however, the Lidocaine group showed a trend of pain reduction only in PHN. The Dextrose group except CRPS showed increased satisfaction two weeks after the final PIT. Conclusion: From the results, it is suggested that PIT with buffered 5% dextrose may have a good effect for neuropathic pain without any side effect except for patients with CRPS. This may offer a window into a new tool that practitioners can employ in their quest to help patients with neuropathic pain.

A Trend for Atroventricular Valve Regurgitation after a Modified Fontan Operation (변형 폰탄 수술 시행 이후에 방실 판막 폐쇄부전의 변화 양상)

  • Lim, Hong-Gook;Lee, Chang-Ha;Seo, Hong-Joo;Kim, Woong-Han;Hwang, Seong-Wook;Lee, Cheul
    • Journal of Chest Surgery
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    • v.41 no.3
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    • pp.305-312
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    • 2008
  • Background: Anatomic and functional abnormalities of the systemic atrioventricular (AV) valve are common in single ventricle. pathologies and continue to be associated with poor early and late outcomes in surgically palliated single. ventricle patients. We aggressively performed valvuloplasty for atrioventricular valve regurgitation (AVVR) during the course toward a Fontan operation. Material and Method: Between January 1995 and December 2004, 209 patients underwent a Fontan operation in our institution. We retrospectively evaluated the prevalence of AVVR and the influence of AV valve repair on outcome, and we analyzed the progression of AVVR after the Fontan operation for 168 patients where echocardiographic follow up results for more than 6 months after the Fontan operation were available. During the course toward a Fontan operation, 25 patients underwent 30 procedures for AVVR. These procedures. were. carried out during placement of a bidirectional cavopulmonary shunt (BCPS) for nine patients, between the time of placement of a BCPS and the Fontan operation for four patients, and during the Fontan operation for 17 patients. Five patients underwent procedures for AVVR twice. Result: The late mortality rate after the Fontan operation was 4.2% (n=7), with a median follow-up duration of 52 months (range, $6{\sim}123$ months). Seven patients (4%) had unfavorable outcomes such as significant (moderate or severe) AVVR in six patients, and significant AV valve stenosis in one patient was determined at the last follow up after the Fontan operation. Among the seven patients, four patients underwent AV valve repair after the Fontan operation, and one patient underwent subsequent AV valve replacement. Progression to AVVR of equal to or greater than grade 2 was noted in 30 patients (18%) at the last follow up after the Fontan operation, including 12 patients that underwent previous AV valve procedures. Initial grading of AVVR, a previous AV valve operation, and specific AV valve morphology such as a common AV valve or mitral atresia were significant risk factors for the progression of AVVR after the Fontan operation. Conclusion: In our surgical series, a small percentage of patients showed unfavorable outcomes. related to AVVR during the course toward a Fontan operation. However, a closer follow-up is required to evaluate the progression of the AVVR after a Fontan operation, especially for patients showing poor AV valve function at the first presentation and specific AV valve morphology.

The Results and Prognostic Factors of Postoperative Radiation Therapy in the Early Stages of Endometrial Cancer (초기 자궁내막암의 수술 후 방사선치료의 결과와 예후인자)

  • Lee, Kyung-Ja
    • Radiation Oncology Journal
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    • v.26 no.3
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    • pp.149-159
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    • 2008
  • Purpose: To evaluate the results and prognostic factors for postoperative adjuvant radiation therapy in patients at stages I and II of endometrial cancer. Materials and Methods: Between January 1991 and December 2006, 35 patients with FIGO stages I and II disease, who received adjuvant radiation therapy following surgery for endometrial cancer at Ewha Womans University Hospital, were enrolled in this study. A total of 17 patients received postoperative pelvic external beam radiation therapy; whereas, 12 patients received vaginal brachytherapy alone, and 6 patients received both pelvic radiation therapy and vaginal brachytherapy. Results: The median follow-up period for all patients was 54 months. The 5-yr overall survival and disease-free survival rates for all patients were 91.4% and 81.7%, respectively. The 5-yr overall survival rates for low-risk, intermediate-risk, and high-risk groups were 100%, 100% and 55.6%, respectively. In addition, the 5-yr disease-free survival rates were 100%, 70.0%, and 45.7%, respectively. Although no locoregional relapses were identified, distant metastases were observed in 5 patients (14%). The most common site of distant metastases was the lung, followed by bone, liver, adrenal gland, and peritoneum. A univariate analysis revealed a significant correlation between distant metastases and risk-group (p=0.018), pathology type (p=0.001), and grade (p=0.019). A multivariate analysis also revealed that distant metastases were correlated with pathology type (p=0.009). Papillary, serous and clear cell carcinoma cases demonstrated a poor patient survival rate compared to cases of endometrioid adenocarcinoma or adenosquamous carcinoma. The most common complication of pelvic external beam radiation therapy was enteritis (30%), followed by proctitis, leucopenia, and lymphedema. All these complications were of RTOG grades 1 and 2; no grades 3 and 4 were observed. Conclusion: For the low-risk and intermediate-risk groups (stages 1 and 2) endometrial cancer, pelvic control, and overall survival rate was free of severe toxicity when pelvic radiation therapy or vaginal brachytherapy was performed. In the high-risk group, pelvic control rate was excellent, but the survival rate was poor due to distant metastases, in spite of the pelvic radiation therapy. The combined modality of chemotherapy and radiation therapy is recommended for high-risk groups. For the intermediate-risk group, a prospective randomized study is required to compare the efficacy between whole pelvic radiation therapy and vaginal brachytherapy.

The Studies on various Causes of Cleanness Defects with in Raw Silk. (생사의 대중절 발생원인 구명에 관한 연구)

  • 최병희;마석일
    • Journal of Sericultural and Entomological Science
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    • no.12
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    • pp.21-36
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    • 1970
  • This studies have been carried out to 3nd various causes of cleanness defects on raw silk which has been increased since 1967 in Korea, so that this treatise may be a guide inform action to improve such a defect in future. The cocoon treatment for the proposed work was carried starting with in worst condition to find the critical limit of degrading through such a work. And various analysis have been also worked out using the annual silk testing data past a few years. The results obtained are as follows. 1. There was a great relationship between cleanness and neatness result. 2. Cleanness result is greatly influenced by mounting conditions and handling of cocoons, which brought 40 percent lower as cleanness result than standard ones in which caused minor defects, especially loops and split ends, so the bad mounting conditions and handling of fresh cocoons degraded raw silk from 4A grade to E. 3. The use of good water quality brought the difference of 1.04 percent in cleanness result rather than the use of bad one. 4. Well technical work brought the difference of 0.86 percent in cleanness result rather than poor technical work. 5, Satisfactory cocoon drying installation brought the difference of 1.97 percent in cleanness result rather than insufficient one. 6. Automatic reeling machine marked lower 1,55 percent in cleanness result than multi-end reeling machine. 7. The degrading of cleanness result from 1965 year silk to 1969 year silk marked 1.99 percent, which almost responds to the degrading rate from good to poor cocoon drying installed cleanness results. In view of this result, nowadays, insufficient cocoon drying installation may be main factor to be worse cleanness result of Korean raw silk. 8. The factors of cleanness defect in raw silk once supplied with cocoon into factory are water quality, technique evaluation, cocoon drying capacity and s: reeling machine. The relationship between cleanness result and above factors are as follows. cleanness result=neatness result+1.6-1.04(1-a)-1.97(1-b)-0.86(1-c)+1.55${\times}$d a: The successive we ratio of water quality (0\longrightarrowl) b: The successive ratio of satisfactory cocoon drying installation (0\longrightarrowl) c: The successive ratio of well technical work (0\longrightarrowl) d: 1 in case multi-end reeling machine o in case automatic reeling machine 9, It is not admitted that there is heavy relationship between cleanness occurrence and nonbreaking reel ability. That mal$.$ be sowed with silk reeling technique. 10. The bad mounting conditions caused the worse result on the cocoon quality as much as cleanness. 11. Besides mounting conditions, there may be another factors affecting on the low reel ability of cocoons in Korea.

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