• Title/Summary/Keyword: Polyethylene glycol (PEG)

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Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use

  • Jang, Hyun-Jun;Shin, Chan Young;Kim, Kyu-Bong
    • Toxicological Research
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    • v.31 no.2
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    • pp.105-136
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    • 2015
  • Polyethylene glycols (PEGs) are products of condensed ethylene oxide and water that can have various derivatives and functions. Since many PEG types are hydrophilic, they are favorably used as penetration enhancers, especially in topical dermatological preparations. PEGs, together with their typically nonionic derivatives, are broadly utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners. The compounds studied in this review include PEG/PPG-17/6 copolymer, PEG-20 glyceryl triisostearate, PEG-40 hydrogenated castor oil, and PEG-60 hydrogenated castor oil. Overall, much of the data available in this review are on PEGylated oils (PEG-40 and PEG-60 hydrogenated castor oils), which were recommended as safe for use in cosmetics up to 100% concentration. Currently, PEG-20 glyceryl triisostearate and PEGylated oils are considered safe for cosmetic use according to the results of relevant studies. Additionally, PEG/PPG-17/6 copolymer should be further studied to ensure its safety as a cosmetic ingredient.

An Approach to Improve Thermal Insulation Properties and Fabric Hand of Wool and Wool-like Fabrics under High Molecular Polyethylene Glycol Treatment (고분자량 Polyethylene Glycol 처리에 따른 모직물과 유사모직물의 보온성과 태의 향상 방안 모색)

  • 조길수;이은주
    • Journal of the Korean Society of Clothing and Textiles
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    • v.21 no.6
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    • pp.1041-1050
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    • 1997
  • This study was carried out to improve the thermal insulation properties of wool and wool- like fabrics by treating the fabrics with polyethylene glycol, to evaluate the fabric hand of PEG treated wool and wool-like fabrics and to grade up the fabric hand of the treated fabrics by treating with softening agents. Wool and wool-like fabrics were treated with high molecular PEG-8,000 by PDC. The thermal release/storage properties were measured on a DSC. Hand of specimens were evaluated by KES-FB system. The results were as follows; 1. PEG-treated fabrics showed thermal storage and thermal release properties by DSC and the heat contents were generally proportional to the add-ons. 2. PEG-treated fabrics showed higher Koshi and lower Numeri and Sofutosa values due to lower tensile energy and recovery and higher bending rigidity and shear stiffness as the add- ons increased. 3. PEG-treated fabrics showed much lower bending rigidity after softening agents treatment.

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Formation of PEG/Dextran Aqueous Two-Phase System for Starch Hydrolysis Using $\alpha$-Amylase ($\alpha$-Amylase로 전분 가수분해를 위한 PEG/Dextran 수성 2상계 구성)

  • 박병춘;임동준
    • Microbiology and Biotechnology Letters
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    • v.20 no.2
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    • pp.190-195
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    • 1992
  • In the polyethylene glycol/dextran aqueous two-phase systems, volume ratio was increased and partition coefficient was decreased with the increase of potyethylene glycol molecular weight and concentration. However the volume ratio was decreased and the partition coefficient was increased with the increase of dextran molecular weight. On the other hand, the volume ratio and the partition coefficient were decreased with the increase of dextran concentration. Continuous enzymatic hydrolysis of soluble starch with $\alpha$-amylase which was produced by Bacillus amyloliquefaciens IF0 14141 was investigated in polyethylene glycol/dextran aqueous two-phase systems. Nonreacted soluble starch and $\alpha$-amylase were reused in these systems. $\alpha$-Amylase activity was maintained more than 100 hrs by recycling of $\alpha$-amylase from bottom of settler to reactor.

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Effect of Polyethylene Glycol on Cu Electrodeposition (구리전해도금에서 폴리에틸렌글리콜(polyethylene glycol)의 영향 연구)

  • An, Eui Gyeong;Choi, Sun Gi;Lee, Jaewon;Cho, Sung Ki
    • Journal of the Korean Electrochemical Society
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    • v.25 no.3
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    • pp.113-118
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    • 2022
  • In this study, the effect of polyethylene glycol (PEG) on Cu electrodeposition was analyzed using cyclic voltammetry. The adsorption of PEG was affected by the specific adsorption of sulfate ion (SO42-) or chloride ion (Cl-). In SO42--based plating solution, the adsorption of PEG was limited by the adsorbed SO42-. Accordingly, the adsorbed PEG could suppress the electron transfer for Cu electrodeposition, but its effect was not significant. Meanwhile, in the plating solution composed of perchlorate ion (ClO4-) which does not specifically adsorb on Cu surface, a strong suppression effect of PEG was observed and it was proportional to the molecular weight of PEG. On the other hand, when Cl- was specifically adsorbed on Cu surface, the suppression effect of PEG was enhanced because PEG and Cl- formed an interrelated adsorbate. The synergetic effect of PEG and Cl- depended on the composition of the plating solution, which means that the synergy between PEG and Cl- is based on the physical interaction. For example, the hydrophobicity of PEG plays an important role in the interaction, as the suppression effect of PEG derivative having a hydrocarbon tail was further enhanced with the addition of Cl-.

Study of Synthesis and Property of Eu-PEG Phase Change Luminescent Materials (Eu-PEG로 구성된 상변환 발광재료의 합성 및 물성에 대한 연구)

  • Gu, Xiao-Hua;Xi, Peng;Shen, Xin-Yuan;Cheng, Bo-Wen
    • Polymer(Korea)
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    • v.32 no.4
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    • pp.305-312
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    • 2008
  • A novel TPC-PEG-TPC with active end-groups was obtained from the end-groups of polyethylene glycol (PEG) modified by terephthaloyl chloride (TPC). These active end-groups can link up with a rare earth ion, which is a luminescent center of a rare earth fluorescent complex. Complexes of Eu-PEG with novel ligands (TPC-PEG-PTC) were synthesized by the coordination of the active reactant (as the first ligand) and phenanthroline (as the second ligand) with $Eu^{3+}$.IR, $^1H$-NMR, element analysis, DSC, WAXD, fluorescent spectroscopy, TGA, and SEM were used to characterize the structure and properties of these complexes. The results showed that this type of complex is a heat storage material with the phase change character of polyethylene glycol (PEG) and the luminescent properties of europium. There was no thermal decomposition of the complex of Eu-PEG until $300^{\circ}C$. SEM showed that the complex of Eu-PEG can be dispersed in PE.

Dimensional Stability of Domestic Small-diameter Timbers Treated with Polyethylene Glycol (PEG(Polyethylene glycol)처리에 의한 국내산 주요 소경재의 치수 안정화에 관한 연구)

  • Kwon, Goo-Jung;Kim, Nam-Hun
    • Journal of the Korean Wood Science and Technology
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    • v.30 no.1
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    • pp.40-47
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    • 2002
  • This study was carried out to investigate the dimensional stability of three softwoods (Pinus densiflora S. et Z., Pinus koraiensis S. et Z., Larix kaempferi CARR.) and two hardwoods(Quercus mongolica F., Quercus variabilis BL.) treated with polyethylene glycol(PEG). Existence of PEG in wood was examined by an X-ray diffraction method. Shrinkage of the sample woods decreased with increasing concentration of PEG. The dimensional stability of five species had improved highly in thirty percent solutions of PEG with molecular weight 1000~4000, and the dimension of PEG-treated softwoods was more stable than that of PEG-treated hardwoods. Weight gain and bulking effect of the woods treated with PEG increased with increasing concentration of PEG. X-ray diffractograms of Pinus koraiensis wood treated with PEG showed two peaks derived from PEG crystal at 2𝜃 = 19° and 2𝜃 = 23°. However, the diffractograms of Quercus mongolica wood did not present any peaks caused by PEG crystal. From the result of X-ray diffraction, it was revealed that the content of PEG in Pinus koraiensis wood was higher than that in Quercus mongolica wood.

Dehydration of Opuntia ficus-indica and Aloe vera Slices Using Polyethylene Glycol and Comparison with Other Drying Methods (폴리에틸렌글리콜 처리에 의한 백년초, 알로에 절편의 탈수 및 건조와 기존 건조 방법과의 비교)

  • Yu, Dong-Jin;Wang, Suk-Mae;Song, Kyung-Bin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.7
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    • pp.1024-1029
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    • 2010
  • Opuntia ficus-indica and Aloe vera slices were dried using 20, 30, and 40% polyethylene glycol (PEG) 4,000 as a dehydration agent, and the dried samples were compared with the hot-air dried and freeze dried in terms of rehydration ratio, color, and sensory evaluation. The moisture content of the PEG-treated samples decreased with increasing concentrations of polyethylene glycol. The rehydration ratio of the PEG-treated samples was better than those of the hot air-dried or freeze-dried samples. The color of the PEG-treated samples was similar to that of the freeze-dried samples and better than that of the hot air-dried samples. The sensory evaluation of PEG-treated samples was better than those of the hot air-dried or freeze-dried samples. These results suggest that dehydration of Opuntia ficus-indica and Aloe vera slices using PEG is very effective in terms of rehydration ratio and minimal damage of cell structure.

Microbial Degradation of Polyethylene Glycol (Polyethylene Glycol의 미생물학적 분해)

  • 이종근;이상준;이재동;박송희;박재림
    • Korean Journal of Microbiology
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    • v.24 no.3
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    • pp.329-334
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    • 1986
  • The bacteria capable of utilizing polyethylene glycol(PEG) 6,000 as a sole carbon source were isolated from soil and sewage water connected to factory area. The isolate designated as EL-033 had high biodegradability on PEG 6,000, and was identified as Micrococcus sp. Micrococcus sp. EL-033 could grow on and degrade di-, tri-, tetraethylene glycols and PEGs with molecular weight up to 6,000 and very slowly stilize PEG 20,000 as sole carbon source, but not degrade ethylene glycol. The growth rate of isolate was increased in the higher molecular weight PEGs. The optical culture medium was established to be as follow: PEG 6,000, 0.2%(w/v); $K_2HPO_4$, 0.1%; $NaH_2PO_4{\cdot}12H_2O,\;0.1%\;:\;MgSO_4{\cdot}7H_2O$, 0.05%; polypeptone, 0.1% in distilled water, pH7.5. About 90% of PEG 6,000 was degraded in exponential phase of 48h culture and PEG 6,000 was completely degraded during 72h.

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Comparison of polyethylene glycol 4000 and lactulose for treatment of chronic functional constipation in children (소아의 만성 기능성 변비 치료에 polyethylene clycol 4000과 락툴로스의 효과 비교)

  • Uhm, Ji Hyun
    • Clinical and Experimental Pediatrics
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    • v.50 no.8
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    • pp.752-756
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    • 2007
  • Purpose : The aim of this study was to compare 2 laxatives, namely, polyethylene glycol 4000 without electrolytes and lactulose, evaluating the efficacy and safety for the treatment of constipation in children. Methods : Fifty-six children with chronic functional constipation were randomly assigned to receive polyethylene glycol 4000 (24 patients) or lactulose (32 patients). Patients or their parents reported defecation frequency, stool consistency, abdominal pain, stool incontinence and side effects after 1, 3, 6 and 12 months of treatment. Percentage of recovered patients were compared with each group. Results : Defecation frequency, abdominal pain and stool incontinence were improved in each group. At 12 months of follow up, 60% of patients treated with polyethylene glycol and 57.7% of patients treated with lactulose were considered as recovered. Conclusion : In this study, both polyethylene glycol and lactulose were equally effective and safe in the long-term treatment of constipation in children. There were no significant differences in recovery rates between 2 groups.

Polyethylene Glycol Plus Electrolytes with Stimulant Laxative in Paediatric Faecal Disimpaction: A Randomised Controlled Study

  • Acharyya, Bhaswati C;Bhattacharyya, Chandrayee;Mukhopadhyay, Meghdeep;Acharyya, Saumyabrata
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.2
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    • pp.230-237
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    • 2021
  • Functional constipation is common in the paediatric population all over the world. Effective disimpaction to evacuate the impacted faecal matter forms an essential initial step in the management of constipation. Though different regimens of polyethylene glycol 3350 with electrolytes (PEG+E) are accepted as the prime medication for disimpaction, response is not always satisfactory. A randomised prospective study was undertaken, in a tertiary paediatric Gastroenterology centre to find out the outcome of a 2-day disimpaction when a stimulant laxative sodium picosulphate was added to PEG3350+E (PEG+E+PS group) and comparing it with the outcome using PEG3350+E (PEG+E group) alone. Hundred and one children were randomised into two groups to receive PEG+E+PS and PEG+E. Results revealed that PEG+E+PS group proved significantly superior to PEG+E group in most of the efficacy-parameters in terms of disimpaction as well as long-term management of constipation. Though stimulant laxatives are being used for disimpaction, comparative data are lacking. This was the 1st such comparative study looking at the efficacy of these two processes of disimpaction along with long term effect on treatment.