• Textile Coloration and Finishing
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• v.16 no.1
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• pp.48-52
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• 2004

Diffusion/penetration rates of finishing agents are not a major criterion in the design of low molecular weight finishing agents. However, in the case of polymeric finishing agents, high molecular weights result in large hydrodynamic volumes and diffusion/penetration of the finishing agent into the substrate may become a critical factor in the design of textile finishing agents. Thus the effect of the molecular weight of a model compound, polyethylene glycol, on its diffusion through a cellulose membrane or cotton fabric is studied. Diffusion experiments of polyethylene glycol of molecular weight 400, 1000, 2000, 4600, 8000, and 10000 through cellulose membrane or fabric was carried out in a glass U-tube diffusion apparatus and the half penetration times and the penetration coefficients were determined. Both the half penetration times and the penetration coefficients exhibited a significant change between molecular weight 2000 and 2500 as the molecular weight of polyethylene glycol increased, suggesting that there is a critical molecular weight above which diffusion/penetration becomes difficult. Based on this study on a model compound, it is suggested that polymeric textile finishing agents can be expected to exhibit similar behavior.

• Journal of Nutrition and Health
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• v.29 no.2
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• pp.153-158
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• 1996

Polyethylene glycols(PEGs)are hydrophilic molecules that have been used to characterize intestinal permeability via the paracellular pathway. Using a mixture of PEGs(400, 600 and 1000), containing oligomers in the molecular weight range 330 to 1122 D, the molecular weight permeability dependence in the jejunum of the rat small intestine was examined, employing an in situ recirculation perfusion technique. Individual oligomers were determined by HPLC with refractive detection. In the range studied, a distinct molecular weight cut-off was not apparent. Corrected for the length of jejunum used in the study, over the molecular weight range 330 to 1122D, the apparent permeability(Papp) of PEG ranged from 4.92$\pm$0.02$\times$10-5cm/sec(mean$\pm$SEM, n=5) to 0.28$\times$10-5cm/sec. Also, it was observed that the apparent permeability was inversely proportional to approximately MW2. The results in this study suggest that molecular weight is an important factor in determining the intestinal permeability.

• Bulletin of the Korean Chemical Society
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• v.31 no.7
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• pp.1859-1862
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• 2010

A convenient one-pot condensation route has been developed for obtaining 5-[(2-(piperidin-1-yl) quinolin-3-yl) methylene]-2,4-thiazolidinediones using multicomponents, 2-chloro-3-formyl quinolines, piperidine, 2,4-thiazolidinedione and safer medium/mediator, polyethylene glycol-400.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.410.2-411
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• 2002

Ketoprofen (KP), a potent analgesic and non-steroidal anti-inflammatory drug, has some disadvantages such as gastro-intestinal irritation. short half-life (1.5-4 hour) in plasma and low solubility in aqueous solution. In order to minimize these disadvantages. we have recently prepared a KP prodrug, KP-polyethylene glycol conjugate (KPEG750, PEG Mw=750), and investigated its pharmacokinetic behavior. anti-inflammatory and analgesic effect. (omitted)

• Proceedings of the Membrane Society of Korea Conference
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• 2005.05a
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• pp.104-107
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• 2005

• Journal of the Korean Chemical Society
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• v.52 no.4
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• pp.362-368
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• 2008

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3181-3182
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• 2013

• Proceedings of the Korean Fiber Society Conference
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• 2001.10a
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• pp.195-198
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• 2001

최근 지능재료에 관한 연구가 형상기억합금, 반도체 재료, 의료용 재료, 고분자 재료 등에서 활발히 이루어지고 있다. 지능재료 중 형상기억재료는 형상기억, 형상고정, 충격흡수 등의 효과를 갖기 때문에 열적, 역학적, 전기적 및 자기적(magnetic) 자극을 감지함으로써 형상, 위치, 탄성계수, damping, 마찰 등의 특성변화를 통하여 응답을 할 수 있어 응용이 다양하다 형상기억고분자의 경우 가볍고 형상회복률이 높으며 가공성이 우수한 장점을 가지고 있다. (중략)

• Macromolecular Research
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• v.11 no.5
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• pp.317-321
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• 2003

In order to prepare a prodrug, poly(polyethylene glycol methacrylate-co-methacryloyloxymethyl-5-fluorouracil) (poly(PEGM-co-MAOFU)) prodrug particles were prepared by precipitation polymerization of MAOFU and PEGM in polyacrylic acid solution. The size of prodrug particles were 0.2-0.35 ${\mu}{\textrm}{m}$. The antitumor activity of prodrugs against sarcoma-l80 tumor cell in mice was demonstrated and the polymer particles themselves showed low toxicity and good biocompatibility when they were administrated into mice.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.426.1-426.1
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• 2002

In this study. we modified the cationic liposomes by polyethylene glycol (PEG)-grafted or PEG-added methods. The PEG-grafted transfection complexes were prepared by adding the plasmid DNA to the PEG-grafted cationic liposomes, composed of PEG and cationic lipids. PEG-added transfection complexes were prepared by adding the PEG to the mixture of cationic lipids and plasmid DNA. The particle sizes of PEG-modified transfection complexes did not change during storage compared to conventional transfection complexes. (omitted)