• Proceedings of the Korea Society of Mathematical Education Conference
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• 2006.05a
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• pp.183-197
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• 2006

• The Journal of Sustainable Design and Educational Environment Research
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• v.8 no.2
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• pp.22-39
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• 2009

The purpose of this study was to analyze the school location and site planning direction for land use planning of public land development. And this research proposed the direction of small park in school. So this research present the implication on urban planning and design for architecture, park-school complex. This study perform the relationship analysis on location of school and park. The result follows as this : 1) land use planning : Location and space of park-school must be checked in advance. Schools and parks are placed together. The park is located south of the school. 2) school site planning : Small field for dynamic activity is needed in school. The character of small park in school is relationship of educational programs. 3) management : CCTV is installed at school. Bright lights are placed in school. This result will be used in decision-making-process of land use planning, public land development construction, urban design and city policy.

• Molecules and Cells
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• v.43 no.5
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• pp.459-468
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• 2020

Nuclear receptor subfamily group H member 4 (NR1H4), also known as farnesoid X receptor, has been implicated in several cellular processes in the liver and intestine. Preclinical and clinical studies have suggested a role of NR1H4 in colon cancer development; however, how NR1H4 regulates colon cancer cell growth and survival remains unclear. We generated NR1H4 knockout (KO) colon cancer cells using clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein-9 nuclease (CAS9) technology and explored the effects of NR1H4 KO in colon cancer cell proliferation, survival, and apoptosis. Interestingly, NR1H4 KO cells showed impaired cell proliferation, reduced colony formation, and increased apoptotic cell death compared to control colon cancer cells. We identified MYC as an important mediator of the signaling pathway alterations induced by NR1H4 KO. NR1H4 silencing in colon cancer cells resulted in reduced MYC protein levels, while NR1H4 activation using an NR1H4 ligand, chenodeoxycholic acid, resulted in time- and dose-dependent MYC induction. Moreover, NR1H4 KO enhanced the anti-cancer effects of doxorubicin and cisplatin, supporting the role of MYC in the enhanced apoptosis observed in NR1H4 KO cells. Taken together, our findings suggest that modulating NR1H4 activity in colon cancer cells might be a promising alternative approach to treat cancer using MYC-targeting agents.

• Journal of Society of Preventive Korean Medicine
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• v.24 no.2
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• pp.83-94
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• 2020

Backgrounds : To reduce the patients' economic burden of herbal decoctions use, in 2012, Korean government decided to implement the pilot project of herbal decoctions coverage in the National Health Insurance. Objectives : This study aimed to analyze the policy decision-making process for the pilot insurance project in 2012. Methods : Official documents, research papers, statistical reports, and news articles, etc. on the coverage of herbal decoctions were searched and collected. We used the Kingdon's Policy Stream Model to analyze how the policy of pilot project of herbal decoctions coverage was decided, and who were the main activists for the decision-making process. Results : Components to be included in the 'Problem stream' were the decline in the profits of Korean Medicine institutions, the contraction of the herbal decoctions use, and the fiscal surplus of National Health Insurance. In the 'Policy stream', there were several model studies for herbal decoctions coverage, and examples of herbal benefits in other social insurances. In the 'Political stream', there were the legislative initiatives by member of the National Assembly and the promotion of insurance coverage by the Association of Korean Medicine(AKOM), etc. Policy window for herbal decoctions coverage was opened by the combination of these three streams with the efforts of policy activists, such as the executives of AKOM, and policy researchers. Conclusions : The policy decision process for health insurance coverage of herbal decoctions was analyzed using Kingdon's model, and the analysis shows that the combination of political streams and entrepreneurs' competencies can be an important driving force in policy decision making.

• STI Policy Review
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• v.1 no.2
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• pp.69-88
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• 2010

This paper explores the determinants of the innovation impact of publicly funded R&D projects along three broad dimensions, namely project, firm and market-related factors. In addition to these factors we examine the attributes of the research result per se and aspects of the commercialization process. The observations from empirical and qualitative analyses are based on R&D projects funded by the Fifth and Sixth Research Framework Programmes of the European Union. Firm size, prior experience, innovation culture, the nature of the project itself, explicit intension to commercialize, consortium management and strategy are the factors with the strongest effect on project success, defined in terms of product/process innovation and/or technical knowledge creation. The paper provides important implications for the organization, objectives, and management of public programmes that fund R&D and for project and participant selection.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2014.06a
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• pp.215-220
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• 2014

The report analyze the current situation of shipping industry in Viet Nam, including information about Viet Nam seaborne trade, shipping companies, sea-going fleets, seafarers, major seaports. Afterward it will be disclosed the policy of sea transport in Viet Nam. And finally, the author will give summary and conclusion about shipping industry in Viet Nam.

• Health Policy and Management
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• v.23 no.4
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• pp.397-414
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• 2013

There have been numerous attempts at finding factors associated with profitability among hospitals in the Republic of Korea. Factors that have been shown to be related to hospital profitability have not yet been systematically reviewed. The purpose of this study was to compile and summarize published works investigating the factors associated with hospital profitability in the Republic of Korea. We searched Research Information Sharing Service, Korea studies Information Service System, Database Periodical Information Academic, Korean Medical Database, KoreaMed, and Google Scholar from 1980 to November 2013. In addition, we manually searched reference lists from eligible studies. Review of 20 peer-reviewed articles revealed that very few of the variables employed in the eligible studies exerted consistent association with profitability, with the exception of personal cost (i.e., employee salaries). Future studies should take our findings into consideration before conducting research on hospital profitability.

• Journal of Families and Better Life
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• v.31 no.3
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• pp.1-13
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• 2013

The purpose of this study was to examine the influence of family mealtime and family functioning (family cohesion, family adaptability, and communication with father and mother) on early adolescent school adaptation. Data of 3,145 middle school students from the Survey on the Family Values and Lives among Adolescents(2010) conducted by National Youth Policy Institute(NYPI) were used. The findings are as follows. First, there were significant differences in the frequency of having breakfast and dinner with father and having breakfast with mother, family cohesion, and communication with father according to gender. Second, hierarchical linear regression analyses revealed that household economic status, mother's employment status and adolescents' gender among demographic characteristics, having breakfast with father and having dinner with mother in family mealtime frequency, and all the variables of family functioning predicted adolescents' school adaptation. Finally, economic status, having dinner with mother, family cohesion, and communication with father and mother were associated with adolescents' school adaptation for both boys and girls. Mother's education and having breakfast with father were found to be significant for only boys, while mother's employment status and family adaptability were found to be significant for only girls. These findings could provide grounds for making family and education policy.

• Journal of Information Technology Applications and Management
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• v.28 no.1
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• pp.33-41
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• 2021

In this study, we estimated the number of secondary COVID-19 infections caused by students with potential transmission potential home. When the existing Monte Carlo method was applied to Korean data, the average number of household members of the second COVID-19 infected was predicted. The summary of this study is as follows. First, in general, the number of secondary infections by students returning home from school is greatly influenced by the virus infection rate of each student group they contact while returning home from school. Korea-based empirical research on this is needed. Second, the number of secondary infections by Korean students was relatively lower than that of previous studies. This can be interpreted as being due to the domestic furniture structure. Third, unlike previous studies that assumed the distribution of secondary infected individuals as normal distribution, assuming a negative binomial distribution, the number of secondary infected individuals was sensitively changed according to the estimated parameters. Interpretation of this result shows that the number of secondary infections may vary depending on the time of decision making, the target region, and the target student group. Finally, according to the results of this analysis, a proposal was made to support education policy decisions.

• Korean Security Journal
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• no.37
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• pp.295-323
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• 2013

This study's purpose examine the "Four Social Evils" policy during about seven months and presents new policy and policy directions with a critical eyes. The present Government focus 'The safety of the people' in 2013. But, most of all, "Four Social Evils" selected the top priority project of the government that will be worked on for the next five years. "Four Social Evils" means Sexual Violence, School Violence, Domestic Violence and Unsanitary Food as crimes affecting the daily lives of the people. To date, we were having a number of discussions with various people. But currently, there is a lack of research on constructive criticism about "Four Social Evils" policy. Therefore, It is the best thing to get interested in "Four Social Evils" policy and evaluate the effectiveness at this time. But, This study is not simply criticizing the "Four Social Evils" policy. Ultimately, through this constructive criticism, this study is trying to encourage "Four Social Evils" policy in the right direction and serve as the groundwork for reinforcement strengthen of the social safety net.