• Title/Summary/Keyword: Point of Delivery

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Nanoparticle Inducing Device for Effective Drug Delivery System (효과적인 약물전달 시스템을 위한 나노입자 유도 장치)

  • Lee, Chongmyeong;Han, Hyeonho;Jang, Byonghan;Oh, Eunseol;Key, Jaehong
    • Journal of Biomedical Engineering Research
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    • v.38 no.3
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    • pp.102-110
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    • 2017
  • Cancer is one of the most challenging human diseases. Current clinical methods have limitations for early-stage cancer diagnosis and effective therapy. Moreover, current surgical methods to remove tumors are not precise enough and chemotherapy destroys normal tissues as well as malignant tumors, resulting in severe side effects such as hair loss, vomiting, diarrhea, and blood disorders. Recently, nanotechnology using nano-sized particles suggests advanced solutions to overcome the limitations. Various nanoparticles have been reported for more accurate diagnosis and minimized side effects. However, current nanoparticles still show limited targeting accuracy for cancer generally below 5% injection dosage. Therefore, herein we report a new nanoparticle inducing device(NID) to guide the nanoparticles externally by using both variable magnetic fields and blood flows. NID can be a promising approach to improve targeting accuracy for drug delivery using iron oxide nanoparticles.

A Comparative Study of Reported Nursing Needs and Nursing Care During Labor and Delivery (산부의 간호요구와 간호원의 간호활동과의 비교 연구)

  • 안혜숙
    • Journal of Korean Academy of Nursing
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    • v.6 no.1
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    • pp.51-59
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    • 1976
  • Contemporary nursing is concerned with meeting patients physical psychological and secio-economical needs and with helping persons to sore their own problems. At the time of confinement and delivery, women often have physical and psychological disco- mort related to fear, tension or anxiety. Pain related to these causes varies with the individual woman. Effective nursing care to meet individual needs during labor and delivery is important if nurses are to understand and relieve woman's physical and psychological pain. A questionnaire prepared for the purpose by the investigator was administered to 162 women in two general hospitals, one in Seoul and one in TaeGu, during August 1 and September 20, 1975 and to the 13 delivery-room nurses who cared for them. It was hoped that the study would contribute to comprehensive nursing care during labor and delivery and to improve maternal and child health. 1. The sample of mothers ranged in age from 18 to 39; the majority were from 25 to 29 years old (54.3%). Most of them were housewives (87.6%). Sixty-three percent had high school or higher education. They had a range of one to seven deliveries. Sixty-one percent were primiparas Most had some prenatal care (87.6%). 2. The age of the group of nurses ranged from 22 to 39. Ten were 22 or 23. Five of the 13 had from six to ten months experience in the de]ivory room. Twelve were single and ten had a religious affiliation. 3. Both primiparas and multiparas thought equally that physical and psychological care, nursing skills and attitudes were important during labor and delivery, but did not relate basic nursing care directly to normal delivery. Need for nursing care was rated more highly by primiparas (2.83-3.48) than by multiparas (2.51-3.17) (p〈0.05). 4. There was no difference in need for nursing care according to the educational level of the women nor according to whether they had a religious affiliation or not (p〉0.05). 5. There was no difference in the reported nursing care given regarding of the educational preparation of the nurses (p〉 0.05). 6. There the reported nursing needs of the women and the reported nursing care given were compared, physical and psychological nursing care directed toward protecting the mother and fetus and a safe do]ivory were considered important by both groups. Neither group related simple nursing care directly to protection of the mother and fetus or to a safe delivery. The women rated highly their needs for nourishment (3.05) and having a relative with them (2.90) for emotional support but there was little evidence (2.39) that the nurses provided care to meet these needs (p〈0.05). In conclusion, the nursing needs of the women during the three stages of labor and the nursing care given were generally similar. The women had more psychological needs than physical needs but in comparison, nurses gave a little more physical than psychological care. The results point up the need to make adjustments in labor and delivery room nursing care the nurse should Prepared to pay more attention and bigger consideration in psychological comfort care than physical care.

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A Study on Verification of Delivery Ratio Methodology for Basic Plan at TPLMs(Total Pollutant Load Management System) (수질오염총량관리계획 수립을 위한 유달율 적용방안 검증 연구)

  • Lee, Sung Jun;Rhee, Han Pil;Park, Ji Hyung;Kim, Yong Seok;Hwang, Ha Sun
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.12
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    • pp.714-722
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    • 2017
  • The TPLMs is a system to manage the total amount of pollutants discharged from the watershed in order to achieve the target water quality of the river. In this process, the pollutant load can be classified into generation, discharge and delivery load. When using equation 2, the discharge coefficient should be 1. In case of using equation 3, it is considered that the discharge coefficient defined in the Technical Guideline should be applied. The delivery load is calculated as the product of the discharge load and the delivery ratio, and the delivery ratio is defined as the rate at which the pollutant discharged from the watershed reaches a specific point in the stream. In this study, the delivery ratio estimation method proposed by Hwang (2016) was applied to the Yonggang watershed in the Nakdong river. And the input data of QUALKO2 model was generated by using the estimated delivery ratio (equation 3) and the validation study was conducted by comparing with DRave (equation 2). As a result of the study, it is possible to use both the equation 2 and the equation 3, but it is necessary to change the methodology according to the application of the discharge coefficient.

A Study on the Design of Korean Address Delivery Point Code (한국 주소의 배달점 코드(DPC:Delivery Point Code) 설계 방안에 관한 연구)

  • Wang, Seung-Jin;Kim, Ho-Yon;Lee, Sang-Ho;Nam, Yun-Seok
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.11c
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    • pp.2341-2344
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    • 2002
  • 우편물량 처리에서 병목현상의 원인이 되고있는 수작업에 의한 순로구분 작업을 원활하고 신속하게 처리하며 집배원의 업무 부담을 경감시키기 위해 자동화가 시도되고 있다. 이러한 자동화된 순로구분기의 개발에 있어 순로구분에 필요한 주소 데이터 베이스를 관리하기 위해서는 각 배달지점에 대한 고유한 ID 부여가 필요하다. 따라서 본 논문에서는 아직 체계화되지 않은 한국 주소의 배달점 코드 설계 방안에 대해서 연구하였다. 먼저 해외 각국의 배달점 코드할당 방법을 알아보고, 배달점 코드의 기본 정의 및 설계 방향을 제시한다. 그리고 각 주소의 고유한 배달점 코드를 설계하는데 있어 여러 가지 방안을 제시하고 각 대안별 장단점 및 설계 방법을 제시하였으며 적합한 설계 방안을 선정하였다. 또한 기존의 주소체계뿐만 아니라 도입 예정인 새주소 체계와의 적합성도 고려하였다. 본 논문에서 제시한 우편번호 앞 3자리와 6자리의 일련번호를 연결한 배달점 코드가 현재의 한국 주소체계 뿐만 아니라 새주소 체계에도 적합할 것으로 판단된다. 마지막으로 몇 가지 적용 사례를 통한 제안한 방안들을 검증해 보았다.

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A Study on Estimated Pollutant Delivery Load for the Basic Plan of TPLC (수질오염총량관리계획 수립을 위한 유달부하량 추정방법 연구)

  • Hwang, Ha Sun;Rhee, Han Pil;Ahn, Ki Hong;Park, Ji Hyung;Kim, Yong Seok;Lee, Sung Jun
    • Journal of Korean Society on Water Environment
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    • v.32 no.4
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    • pp.375-383
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    • 2016
  • Total Pollution Load Control (TPLC) calculates and manages the allowable pollutant load that is discharged from the watershed, which can meet the water quality target. Delivery Ratio (DR) is generally used for predicting the variation of pollutant mass balance between the pollutants discharged from the watershed and a certain point in the stream, and it is very important for estimation of accurate allowable pollutant load. The concept of DR in TPLC is different from prevalent DR, because DR in TPLC includes both the discharge of pollutants from the watershed and the delivery mechanism. Therefore, DR in TPLC should be estimated by using a proper and unified methodology. The appropriate method and equation for estimation of DR in TPLC was developed through the review of various methodologies, and the applicability of the equation was evaluated in a study area (Geumho A). Determination coefficients (R2) of regression were shown to be relatively high (BOD 0.71~0.87, T-N 0.86~0.90, T-P 0.62~0.69). Applicability of the developed methodology and equations was evaluated as appropriate for TPLC, and it is suggested.

A Longitudinal Study on Maternal Iron and Folate Status During and After Pregnancy in Korean Women (임신기간과 분만 후 모체의 철 및 엽산 영양상태의 종단적 변화)

  • 이종임;임현숙
    • Korean Journal of Community Nutrition
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    • v.6 no.2
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    • pp.182-191
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    • 2001
  • Anemia in women during pregnancy and after delivery has been known to affect the mother, the fetus, and the infant's growth and health status. Studies examining, changes in iron and folate status associated with anemia during pregnancy and during pregnancy, and those supplements are stopped after postpartum. However, the effects of those have not been clearly determined in pregnant and lactating Korea women. Therefore, this study was performed to determine the changes in maternal iron and folate status during pregnancy and six months after delivery longitudinally in six pregnant women who consumed supplements from 20 wk to delivery. We concluded that the iron status deteriorated during pregnancy and especially was weak in the third trimester, but had a tendency to recovery after delivery. On the other hand, the folate status deteriorated in the first and second trimester and was good in the third trimester, but had a tendency to decrease after delivery. These results suggested that the iron status was not improved despite consuming total iron supplements of 50 mg/day through diets and supplements during the second half of the pregnancy. On the other hand, the folate status improved at the end of pregnancy by consuming folate supplements of a total of 800 mg/day through diets and supplements. However, folate status was poor in the first half of the pregnancy, and the tendency of folate status to decrease during postpartum was advanced. At the point in which iron and therefore supplementation is essential. However, the effects of supplement intake time and intake dosage need to be verified and the nutritional status changes of postpartum women should be carefully monitored.

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Analysis of Sediment Yields at Watershed Scale using Area/Slope-Based Sediment Delivery Ratio in SATEEC (SATEEC 시스템을 이용한 면적/경사도에 의한 유달률 산정 방법에 따른 유사량 분석)

  • Park, Younshik;Kim, Jonggun;Kim, Narnwon;Kim, Ki-sung;Choi, Joongdae;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
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    • v.23 no.5
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    • pp.650-658
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    • 2007
  • The Universal Soil Loss Equation (USLE) has been used in over 100 countries to estimate potential long-term soil erosion from the field. However, the USLE estimated soil erosion cannot be used to estimate the sediment delivered to the stream networks. For an effective erosion control, it is necessary to compute sediment delivery ratio (SDR) for watershed and sediment yield at watershed outlet. Thus, the Sediment Assessment Tool for Effective Erosion Control (SATEEC) was developed to compute the sediment yield at any point in watershed. In this study, the SATEEC was applied to the Sudong watershed, Chuncheon Gangwon to compare the sediment yield using area-based sediment delivery ratio (SDRA) and slope-based sediment delivery ratio (SDRS) at watershed outlet. The sediment yield using the SDRA by Vanoni, SYA and the sediment yield using the SDRS by Willams and Berndt, SYS were compared for the same sized watersheds. The 19 subwatersheds was 2.19 ha in size, the soil loss and sediment yield were estimated for each subwatershed. Average slope of main stream was about 0.86~3.17%. Soil loss and sediment yield using SDRA and SDRS were distinguished depending on topography, especially in steep and flat areas. The SDRA for all subwatersheds was 0.762, however the SDRS were estimated in the range of 0.553~0.999. The difference between SYA and SYS was -79.74~27.45%. Thus site specific slope-based SDR is more effective in sediment yield estimation than area-based SDR. However it is recommended that watershed characteristic need to be considered in estimating yield behaviors.

A study on applicability of Incoterms to CISG (CISG규정에 Incoterms의 적용가능성)

  • Oh, Se-Chang
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.23
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    • pp.39-70
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    • 2004
  • On the above, character of Incoterms and CISG, applicability of Incoterms to the principles of interpretation of CISG for contracts terms, and to the regulations of delivery and payment of price in connection with applicability of Incoterms to CISG are discussed. Conclusions are as follows : Although both rules is regulations which have to understand in connection with int'l trades of goods but CISG is a comprehensive substantive law in connection with a whole dealing course. On the other hand Incoterms are detailed substantive law of performance for two important sphere, that is to say, delivery and payment in the field of performance of CISG. According to both rules, letter credit is realizing processes of detailed performance for delivery and payment. As professor of Honnold's opinion, the relationship between Incoterms and CISG is peculiar and complementary. Therefore instead of considering the both from a point of pure legal views which both rules raise many problems that still a wait well consolidated and acknowledged answers, we have th consider the both with L/C system that still constitute a main payment system. Particularly ICC and Uncitral know that they are not only directly and indirectly involved in regulating process of the both sets but also can apply Incoterms to CISG on connection with the use of L/C.

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Making inferior alveolar nerve block more comfortable via computer-controlled local anesthetic delivery: A prospective clinical study

  • Gajendragadkar, Kunal;Bhate, Kalyani;Jagtap, Bhagyashree;Santhoshkumar, S.N;Kshirsagar, Kapil;Magoo, Surabhi
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.19 no.3
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    • pp.135-141
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    • 2019
  • Background: The fear of needle insertion and pain during anesthesia is a source of patient dissatisfaction in dentistry. Inferior alveolar nerve block (IANB) remains the most common type of block and is in itself painful. Computer-controlled local anesthetic delivery (CCLAD) has been proven to reduce the pain associated with injection of anesthetics in various blocks. However, the efficacy of CCLAD for IANB in adults remains unknown. Methods: Sixty-four adult patients requiring bilateral IANB were selected and divided into two groups: group A (50 patients receiving IANB via CCLAD) and group B (50 patients receiving IANB using a conventional cartridge syringe). Pain perception and patient comfort were assessed using the visual analog scale and the 5-point semantic scale, respectively. Results: The pain perception was compared between the two groups using the Mann-Whitney U-test, and the P value was 0.003. The patient comfort was also compared using the same test, and the P value was 0.484. Conclusion: A significant difference was observed in the pain perception of the patients during CCLAD. The patient comfort was grossly equal for both techniques.

A Study on Sharing & Delivery System of Educational Information in Public Education (초.중등 공교육에서의 교육정보 공유 및 유통 방안)

  • Suh, Soon-Shik;Kim, Sung-Wan
    • Journal of The Korean Association of Information Education
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    • v.14 no.3
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    • pp.365-373
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    • 2010
  • It is required that public schools in information society should act as a balancer between the equal educational opportunity and development of the personal capacity. However, public schools have faced a situation to be blamed and praised by social parties concerned from the point of view of educational excellence. The aim of this study is to suggest some conceptual ideas for sharing & delivery system of educational information, which is based on the paradigm of web 2.0 characterized as participation, sharing, and openness. To do it, we analyzed the recent technological trends and took a group discussion with leading teachers in educational information.

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