• Proceedings of the Korean Society of Tobacco Science Conference
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• 1997.10a
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• pp.91-113
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• 1997

One mg tar cigarettes represent a growing segment of the market, in various parts of the world but specially in the Far East. Cigarette design of ultra low tar cigarettes is not easy to manage: a simple extension of the techniques used in the design of the low tar segment will usually lead to tasteless cigarettes. A detailed analysis of the design of commercial ultra low tar cigarettes in different countries shows that no 《dominant design》 has yet been adopted. Blend composition, blend density, filter design, degree of filter ventilation all vary in a large range from cigarette brand to cigarette brand, and will influence the puff number, the tar concentration in each puff and ultimately the taste. We will report and comment on the detailed analysis of 17 commercial brands of ultra low tar cigarettes. We will then review the specific influence of tobacco chemical composition, introduction of reconstituted tobacco, influence of cigarette paper characteristics, selection of filter ventilation components on the burn characteristics and tar delivery; to conclude that the commercial success of an ultra low tar cigarette is linked to a very delicate balance between this techniques and... good marking of course!

• The Journal of Korean Physical Therapy
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• v.25 no.3
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• pp.160-166
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• 2013

Purpose: The aim of the study was to survey satisfaction with physical therapy. Methods: After the physical therapy consultation, patients filled in a Korean-language version of the 20-tiem version of the MedRisk Instrument developed for measuring Patient Satisfaction with physical therapy. Items are scored on a five-point Likert scale ranging from strongly disagree to strongly agree. The last two items are general satisfaction and future return to the clinic. Age and gender information was also collected anonymously. Exploratory factor analysis based on principal components analysis with varimax rotation was performed on the first 18 items of the MedRisk Instrument using SPSS v.20. Results: Four factors emerged with eigenvalues greater than 1, and these cumulatively explained 55% of the total variance in item scores. The factors were labelled: Internal, External Positives, External Negatives, and Clinic Presentation. Correlations of the factor scores with the two global items ranged from 0.29 to 0.70 (both p<0.001). Gender differences were only found on the last factor, with male Korean patients rating Clinic Presentation significantly higher than females (p=0.001). Conclusion: Using factor analysis, the proposed factor structure was revealed using the positive and negative components of the external aspects of the physical therapy and by identifying a clinic presentation which contributes to patients' satisfaction. The largest proportion of the variance in Patient Satisfaction was related to clinicians' attention and behaviour. The results of the analysis provide guidelines as to the dimensions of professional physical therapy care and the implications for service delivery and patient experience.

• Pediatric Infection and Vaccine
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• v.11 no.1
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• pp.121-125
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• 2004

Chickenpox is a common childhood infection that generally resolves without complications. But maternal chickenpox near term, or soon after delivery, can cause severe or fatal illness in the newborn. The severity of neonatal chickenpox is closely related to the time of maternal infection and the fatality is reported up to 30%. Although chickenpox is thought to be a mild disease, complications are frequent in neonates and immunocompromised children. The diagnosis of neonatal chickenpox is usually based on the typical clinical feature, the characteristic point in time and the maternal history of chickenpox. Serologic methods have been widely used to confirm clinical diagnosis. To prevent severe neonatal chickenpox, passive immunization is indicated. If varicella occurs, acyclovir treatment has to be done promptly. But the use of acyclovir in symptomatic healthy infant is controversial. We report a case of neonatal chickenpox that was infected by an asymptomatic infected mother and rapid improvement of varicella skin lesions without complications after intravenous acyclovir administration.

• The Korean Journal of Food And Nutrition
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• v.29 no.5
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• pp.716-723
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• 2016

The aims of this study were to investigate usage status, menu preference, quality evaluation and satisfaction of home-delivered meal box for children from low-income families in Chungcheongbuk-do, Korea. A total of 320 children and their guardians who had received home-delivered meal boxes participated in 2015. A total of respondents (62.2%) were children and teenagers, and 37.8% were guardians. The 47.7% of children and 43.8% of guardians were using the home delivery service more than one year. Most of the children and guardians answered 'eat almost', 'eat all meals' served meal box, 75.3%, 81.8%, respectively. After receiving the meal box at home, 35.2% of children consumed meals within 1~2 hours, whereas 32.8% of the guardians were ate within 2~6 hours. It was founded that 'throw away leftovers' was the highest and followed 'give it others' in a way to treat leftovers. The results of preference survey on meats, seafood, showed that 'chicken nugget' (4.07) and 'stir-fried fish cake with vegetable' (3.63) were the highest points for children, whereas 'grilled LA beef ribs' (3.98) and 'stir-fried anchovies' (3.72) were the highest point for guardians. 'Seasoned leaves marinated in soy sauce' was the highest preference among vegetables and another dish for respondents. Frozen products were the most preferred types of meal boxes on the menu. In the quality evaluation of home-delivered meal box, although satisfaction with service and packaging of the meal box were high, the satisfaction of food quality was relatively low.

• Biomolecules & Therapeutics
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• v.20 no.1
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• pp.1-18
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• 2012

Schizophrenia is a devastating psychiatric illness that afflicts 1% of the population worldwide, resulting in substantial impact to patients, their families, and health care delivery systems. For many years, schizophrenia has been felt to be associated with dysregulated dopaminergic neurotransmission as a key feature of the pathophysiology of the illness. Although numerous studies point to dopaminergic abnormalities in schizophrenia, dopamine dysfunction cannot completely account for all of the symptoms seen in schizophrenia, and dopamine-based treatments are often inadequate and can be associated with serious side effects. More recently, converging lines of evidence have suggested that there are abnormalities of glutamate transmission in schizophrenia. Glutamatergic neurotransmission involves numerous molecules that facilitate glutamate release, receptor activation, glutamate reuptake, and other synaptic activities. Evidence for glutamatergic abnormalities in schizophrenia primarily has implicated the NMDA and AMPA subtypes of the glutamate receptor. The expression of these receptors and other molecules associated with glutamate neurotransmission has been systematically studied in the brain in schizophrenia. These studies have generally revealed region- and molecule-specifi c changes in glutamate receptor transcript and protein expression in this illness. Given that glutamatergic neurotransmission has been implicated in the pathophysiology of schizophrenia, recent drug development efforts have targeted the glutamate system. Much effort to date has focused on modulation of the NMDA receptor, although more recently other glutamate receptors and transporters have been the targets of drug development. These efforts have been promising thus far, and ongoing efforts to develop additional drugs that modulate glutamatergic neurotransmission are underway that may hold the potential for novel classes of more effective treatments for this serious psychiatric illness.

• Health Policy and Management
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• v.28 no.1
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• pp.48-52
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• 2018

Background: The current study evaluated the hospital utilization and characteristics of patients who received health care services for acute cerebral infarction outside their own residential area. Methods: Using the 2014 national patient survey data, information on 2,982 patients diagnosed with acute cerebral infarction through emergency department were retrieved for the analyses. Multiple logistic regression was performed to investigate the characteristics associated with using hospitals outside residential area among patients diagnosed with acute cerebral infarction. Results: Fifteen point nine percent of patients admitted for acute cerebral infarction utilized hospitals outside their residential area. Patients residing in a province were 7.7 times more likely to utilize hospitals located outside their residential areas compared to those living in Seoul metropolitan city. Patients living in Gangwon and Jeolla were 0.26 times and 0.48 times more likely to go to hospitals in different geographical areas. Also, patients within the age group of 80 years and over were 0.65 times less likely to be admitted to hospitals outside their residential area compared to those in their 40s-50s. Conclusion: The use of hospitals outside patient's residential area is shown to be substantial, given that the acute cerebral infarction requires immediate recognition and treatment. The findings on the geographical differences in the hospital utilization suggest further investigation.

• Journal of Korean Dental Science
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• v.16 no.1
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• pp.23-34
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• 2023

Purpose: This study aims to investigate the force delivery profile of thermoformed aligners (TFA) compared with direct-printed aligners (DPA) and to explore the effect of different activation amounts on forces and moments of respective groups. A secondary objective is to observe the amount of stress relaxation that occurs over the 7~14 days when aligners are maintained in a simulated intraoral environment. Materials and Methods: An in vitro setup was created to quantify forces and moments. It consisted of a three dimensional-printed base plate and segmented maxillary teeth, placed in a semi-enclosed chamber to maintain a temperature of 37℃. Ninety clear aligners were divided into nine groups of ten aligners each based on material types (Zendura, ATMOS, TC-85) and activation amounts. Aligners were created with 0.00, 0.25- and 0.50-mm activations for lingual bodily movement of the upper left central incisor and kept on models in the "stressed" position in a 37℃ water bath. Three force components acting on the upper left lateral incisor, upper left central incisor, and upper right central incisor were measured for each time point, beginning from the initial baseline measurement, 8 hours, 16 hours, 24 hours, 2 days, 3 days, 4 days, 5 days, 6 days, 7 days, and lastly, 14 days. Result: TC-85 aligners in every activation group showed less force on teeth than Zendura and ATMOS. Significant force levels from 0.0 mm activation were present and stayed consistent over the course of 14 days. Comparisons made for baseline measurements to 7-days and 14-days showed statistically significant change from the baseline force level. Conclusion: TC-85 aligners demonstrated lower, more consistent forces with fewer side effects. Aligners can generate forces even when no activation is programmed. No major decreases in force levels over time were observed; the intra-oral clinical simulated environment and length of observation time could contribute to this.

• Journal of Hydrogen and New Energy
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• v.26 no.2
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• pp.114-119
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• 2015

Nowdays, fossil fuels have been used as an important resource in development of industry. But it is limited and caused climate change such as pollution and global warming. So nuclear fusion research is being issued with tritium to develop eco-friendly and sustainable energy. Republic of Korea is in charge of Storage and Delivery System (SDS) in the International Thermonuclear Experimental Reactor (ITER), weld present in the SDS bottles are easily exposed to the hydrogen embrittlement of special characteristics of the hydrogen in hydrogen atmosphere, When the hydrogen embrittlement is rapidly progresses, the cracking is generated in the weld zone. Due to this cracking, the risk of leakage of tritium into the atmosphere occurs. In this study, hydrogen heat treatment was processed through the Pressure-Composition-Temperature (PCT) device according to the time variation. Also mechanical properties such as rupture strength test, three point bend test and hardness test in accordance with the respective time have been conducted and the fracture was observed by scanning electron microscopy(SEM) after the mechanical properties evaluation.

• Journal of Korean Neurosurgical Society
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• v.30 no.sup1
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• pp.37-43
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• 2001

Object : The rapid and early oxygen delivery to brain tissue was a common therapeutic method in the treatment of severe head injury patients. The purpose of this study was to investigate the effect of increased fraction of inspired oxygen in early stage of severe head injury. Methods : The parameters of research were CSF(cerebral spinal fluid) oxygen pressure($PcsfO_2$), lactate, pH, temperature, and CSF carbon dioxide pressure($PcsfCO_2$). We selected 28 patients with head trauma whose the Glasgow Coma Scale(GCS) score was less than 8 point at admission. All patients were mechanically ventilated and monitored with the commercial ICP monitoring device. Each of parameters was compared as increased fraction of inspired oxygen. In experimental cohort of 14 patients, the mean $PcsfO_2$ level was increased to $314.93{\pm}259.15mmHg$ by raising the $FiO_2$ from 40% to 100% for nine hours(p<0.05). And the mean CSF lactate level was decreased to $2.96{\pm}1.98mmol/L$ on 100% $FiO_2$ as compared with $5.98{\pm}3.25mmol/L$ on 40% $FiO_2$ in control group(p<0.05). The only above two parameters were showed statistically meaningful outcome. Conclusions : Although this study was performed in small cohort and short period, these results supports that increased inspired oxygen therapy in severe head injuried patients was recommended as a modality of treatment in future through the continuous survey.

• Korean Journal of Poultry Science
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• v.26 no.1
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• pp.43-50
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• 1999

The features of special brand eggs are growing more and more diverse and it is hard to draw a clear distinction between these and ordinary (no-brand) eggs. Special brand eggs range from those with objectively recognizable characteristics to those given only an unsubstantial product image and price differentials are among them great, too. The relation between product features and prices is unclear. Special brand eggs are the commodity whose characteristics are the vaguest of all livestock products. Farm's brand eggs produce a high profitability to producers is they are directly sold to consumers, by, for example, home-delivery service. But if they are sold to supermarkets, etc., producer's (poultry farmer's) income becomes lower by the amount of distributors' margin, reducing the profitability substantially. Thus how to increase the ration of retailing is important for farmers to secure a high profit. The sales strategies of poultry are the combination of two elements, that is, new product development (product differentiation) and creation of new market. But it is difficult for special brand egg producers to develop products with clear characteristics (use value) distinct form ordinary eggs and so these producers depend on the factors of appearance, such as the color of egg shells and package. Special brand eggs manage to keep their marketable value by the combination of the few product features and product image. Thus NB eggs from feed producers have a great market-ability since they can take advantage of the power of patents and TV commercials. However, market differentiation affects profitability much more than product features and price gaps are very wide between directly sold and wholesaled eggs. The producers of special brand eggs have come to the turning point where they have to decide whether they will content with being the subcontractors for NB and PB eggs or they will continue to keep their independence in production and marketing.