1 |
Clinton, SM, Haroutunian, V and Meador-Woodruff, JH (2006) Up-regulation of NMDA receptor subunit and post-synaptic density protein expression in the thalamus of elderly patients with schizophrenia. J. Neurochem. 98, 1114-1125.
DOI
ScienceOn
|
2 |
Clinton, S. M. and Meador-Woodruff, J. H. (2004) Abnormalities of the NMDA Receptor and Associated Intracellular Molecules in the Thalamus in Schizophrenia and Bipolar Disorder. Neuropsychopharmacology 29, 1353-1362.
DOI
ScienceOn
|
3 |
Collingridge, G. L., Olsen, R. W., Peters, J. and Spedding, M. (2009) A nomenclature for ligand-gated ion channels. Neuropharmacology 56, 2-5.
DOI
ScienceOn
|
4 |
Coombs, I. D. and Cull-Candy, S. G. (2009) Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum. Neuroscience 162, 656-665.
DOI
ScienceOn
|
5 |
Copits, B. A, Robbins, J. S., Frausto, S. and Swanson, G. T. (2011) Synaptic targeting and functional modulation of GluK1 kainate receptors by the auxiliary neuropilin and tolloid-like (NETO) proteins. J. Neurosci. 31, 7334-7340.
DOI
ScienceOn
|
6 |
Corti, C., Crepaldi, L., Mion, S., Roth, A. L., Xuereb, J. H. and Ferraguti, F. (2007) Altered dimerization of metabotropic glutamate receptor 3 in schizophrenia. Biol. Psychiatry 62, 747-755.
DOI
ScienceOn
|
7 |
Corti, C., Xuereb, J. H., Crepaldi, L., Corsi, M., Michielin, F. and Ferraguti, F. (2011) Altered levels of glutamatergic receptors and ATPase-alpha1 in the prefrontal cortex of subjects with schizophrenia. Schizophr. Res. 128, 7-14.
DOI
ScienceOn
|
8 |
Cousins, S. L., Papadakis, M., Rutter, A. R. and Stephenson, F. A. (2008) Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins. J. Neurochem. 104, 903-913.
DOI
ScienceOn
|
9 |
Coyle, J. T. (1996) The glutamatergic dysfunction hypothesis for schizophrenia. Harv. Rev. Psychiatry 3, 241-253.
DOI
ScienceOn
|
10 |
Rosse, R. B., Schwartz, B. L., Leighton, M. P., Davis, R. E. and Deutsch, S. I. (1990) An open-label trial of milacemide in schizophrenia: an NMDA intervention strategy. Clin. Neuropharmacol. 13, 348-354.
DOI
ScienceOn
|
11 |
Rothstein, J. D., Martin, L., Levey, A. I., Dykes-Hoberg, M., Jin, L., Wu, D., Nash, N. and Kuncl, R. W. (1994) Localization of neuronal and glial glutamate transporters. Neuron 13, 713-725.
DOI
ScienceOn
|
12 |
Sala, C. and Sheng, M. (1999) The fyn art of N-methyl-D-aspartate receptor phosphorylation. Proc. Natl. Acad. Sci. USA 96, 335-337.
DOI
ScienceOn
|
13 |
Sans, N., Prybylowski, K., Petralia, R. S., Chang, K., Wang, Y. X., Racca, C., Vicini, S. and Wenthold, R. J. (2003) NMDA receptor traffi cking through an interaction between PDZ proteins and the exocyst complex. Nat. Cell Biol. 5, 520-530.
DOI
ScienceOn
|
14 |
Sans, N., Wang, P. Y., Du, Q., Petralia, R. S., Wang, Y. X., Nakka, S., Blumer, J. B., Macara, I. G. and Wenthold, R. J. (2005) mPins modulates PSD-95 and SAP102 traffi cking and infl uences NMDA receptor surface expression. Nat. Cell Biol. 7, 1179-1190.
DOI
ScienceOn
|
15 |
Scarr, E., Beneyto, M., Meador-Woodruff, J. H. and Dean, B. (2005) Cortical glutamatergic markers in schizophrenia. Neuropsychopharmacology 30, 1521-1531.
DOI
ScienceOn
|
16 |
Schiffer, H. H., Swanson, G. T. and Heinemann, S. F. (1997) Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate. Neuron 19, 1141-1146.
DOI
ScienceOn
|
17 |
Schmitt, A., Koschel, J., Zink, M., Bauer, M., Sommer, C., Frank, J., Treutlein, J., Schulze, T., Schneider-Axmann, T., Parlapani, E., Rietschel, M., Falkai, P. and Henn, F. A. (2010) Gene expression of NMDA receptor subunits in the cerebellum of elderly patients with schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 260, 101-111.
DOI
ScienceOn
|
18 |
Schoepp, D. D. (2001) Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J. Pharmacol. Exp. Ther. 299, 12-20.
|
19 |
Cuadra, A. E., Kuo, S. H., Kawasaki, Y., Bredt, D. S. and Chetkovich, D. M. (2004) AMPA receptor synaptic targeting regulated by stargazin interactions with the Golgi-resident PDZ protein nPIST. J. Neurosci. 24, 7491-7502.
DOI
ScienceOn
|
20 |
Crook, J. M., Akil, M., Law, B. C., Hyde, T. M. and Kleinman, J. E. (2002) Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects. Mol. Psychiatry 7, 157-164.
DOI
ScienceOn
|
21 |
Cull-Candy, S., Brickley, S. and Farrant, M. (2001) NMDA receptor subunits: diversity, development and disease. Curr. Opin. Neurobiol. 11, 327-335.
DOI
ScienceOn
|
22 |
Danbolt, N. C. (2001) Glutamate uptake. Prog. Neurobiol. 65, 1-105.
DOI
ScienceOn
|
23 |
de Lucena, D., Fernandes, B. S., Berk, M., Dodd, S., Medeiros, D. W., Pedrini, M., Kunz, M., Gomes, F. A., Giglio, L. F., Lobato, M. I., Belmonte-de-Abreu, P. S. and Gama, C. S. (2009) Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. J. Clin. Psychiatry 70, 1416-1423.
DOI
ScienceOn
|
24 |
De Witte, P., Littleton, J., Parot, P. and Koob, G. (2005) Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action. CNS Drugs 19, 517-537.
DOI
ScienceOn
|
25 |
Dev, K. K., Nishimune, A., Henley, J. M. and Nakanishi, S. (1999) The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits. Neuropharmacology 38, 635-644.
DOI
ScienceOn
|
26 |
Devon, R. S., Anderson, S., Teague, P. W., Muir, W. J, Murray, V., Pelosi, A. J., Blackwood, D. H. and Porteous, D. J. (2001) The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol. Psychiatry 6, 311-314.
DOI
ScienceOn
|
27 |
Shibata, H., Tani, A., Chikuhara, T., Kikuta, R., Sakai, M., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. and Fukumaki, Y. (2009) Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia. Psychiatry Res. 167, 88-96.
DOI
|
28 |
Schwenk, J., Harmel, N., Zolles, G., Bildl, W., Kulik, A., Heimrich, B., Chisaka, O., Jonas, P., Schulte, U., Fakler, B. and Klocker, N. (2009) Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science 323, 1313-1319.
DOI
ScienceOn
|
29 |
Sheng, M. and Pak, D. T. (2000) Ligand-gated ion channel interactions with cytoskeletal and signaling proteins. Annu. Rev. Physiol. 62, 755-778.
DOI
ScienceOn
|
30 |
Shi, S., Hayashi, Y., Esteban, J. A. and Malinow, R. (2001) Subunitspecifi c rules governing AMPA receptor traffi cking to synapses in hippocampal pyramidal neurons. Cell 105, 331-343.
DOI
ScienceOn
|
31 |
Singh, S. P. and Singh, V. Meta-Analysis of the Efficacy of Adjunctive NMDA Receptor Modulators in Chronic Schizophrenia. CNS Drugs 25, 859-885.
|
32 |
Singh, S. P. and Singh, V. (2011) Meta-Analysis of the Efficacy of Adjunctive NMDA Receptor Modulators in Chronic Schizophrenia. CNS Drugs 25, 859-885.
DOI
ScienceOn
|
33 |
Sobolevsky, A. I., Rosconi, M. P. and Gouaux, E. (2009) X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462, 745-756.
DOI
ScienceOn
|
34 |
Sodhi, M. S., Simmons, M., McCullumsmith, R., Haroutunian, V. and Meador-Woodruff, J. H. (2011) Glutamatergic gene expression is specifi cally reduced in thalamocortical projecting relay neurons in schizophrenia. Biol. Psychiatry 70, 646-654.
DOI
ScienceOn
|
35 |
Sokolov, B. P. (1998) Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of "neuroleptic- free" schizophrenics: evidence on reversible up-regulation by typical neuroleptics. J. Neurochem. 71, 2454-2464.
|
36 |
Dracheva, S., Marras, S. A., Elhakem, S. L., Kramer, F. R., Davis, K. L. and Haroutunian, V. (2001) N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. Am. J. Psychiatry 158, 1400-1410.
DOI
ScienceOn
|
37 |
Diaz, E. (2010) Regulation of AMPA receptors by transmembrane accessory proteins. Eur. J. Neurosci. 32, 261-268.
DOI
ScienceOn
|
38 |
Dracheva, S., McGurk, S. R. and Haroutunian, V. (2005) mRNA expression of AMPA receptors and AMPA receptor binding proteins in the cerebral cortex of elderly schizophrenics. J. Neurosci. Res. 79, 868-878.
DOI
ScienceOn
|
39 |
Dracheva, S., Byne, W., Chin, B. and Haroutunian, V. (2008) Ionotropic glutamate receptor mRNA expression in the human thalamus: absence of change in schizophrenia. Brain Res. 1214, 23-34.
DOI
|
40 |
Eastwood, S. L., Burnet, P. W. and Harrison, P. J. (1997a) GluR2 glutamate receptor subunit fl ip and fl op isoforms are decreased in the hippocampal formation in schizophrenia: a reverse transcriptasepolymerase chain reaction (RT-PCR) study. Brain Res. Mol. Brain Res. 44, 92-98.
DOI
|
41 |
Eastwood, S. L., Kerwin, R. W. and Harrison, P. J. (1997b) Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-Daspartate glutamate receptors within the medial temporal lobe in schizophrenia. Biol. Psychiatry 41, 636-643.
DOI
ScienceOn
|
42 |
Eastwood, S. L., McDonald, B., Burnet, P. W., Beckwith, J. P., Kerwin, R. W. and Harrison, P. J. (1995) Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. Brain Res. Mol. Brain Res. 29, 211-223.
DOI
|
43 |
Egebjerg, J., Bettler, B., Hermans-Borgmeyer, I. and Heinemann, S. (1991) Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA. Nature 351, 745-748.
DOI
ScienceOn
|
44 |
Straub, C., Hunt, D. L., Yamasaki, M., Kim, K. S., Watanabe, M., Castillo, P. E. and Tomita, S. (2011) Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1. Nat. Neurosci. 14, 866-873.
DOI
ScienceOn
|
45 |
Song, I., Kamboj, S., Xia, J., Dong, H., Liao, D. and Huganir, R. L. (1998) Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors. Neuron 21, 393-400.
DOI
ScienceOn
|
46 |
Steiner, P., Alberi, S., Kulangara, K., Yersin, A., Sarria, J. C., Regulier, E., Kasas, S., Dietler, G., Muller, D., Catsicas, S. and Hirling, H. (2005) Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. EMBO J 24, 2873-2884.
DOI
ScienceOn
|
47 |
Stephenson, F. A., Cousins, S. L. and Kenny, A. V. (2008) Assembly and forward traffi cking of NMDA receptors (Review). Mol. Membr. Biol. 25, 311-320.
DOI
ScienceOn
|
48 |
Takaki, H., Kikuta, R., Shibata, H., Ninomiya, H., Tashiro, N. and Fukumaki, Y. (2004) Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 128B, 6-14.
DOI
|
49 |
Takamori, S., Rhee, J. S., Rosenmund, C. and Jahn, R. (2000) Identification of a vesicular glutamate transporter that defi nes a glutamatergic phenotype in neurons. Nature 407, 189-194.
DOI
ScienceOn
|
50 |
Tamminga, C. (1999) Glutamatergic aspects of schizophrenia. Br. J. Psychiatry Suppl. 37, 12-15.
|
51 |
Tang, M., Pelkey, K. A., Ng, D., Ivakine, E., McBain, C. J., Salter, M. W. and McInnes, R. R. (2011) Neto1 is an auxiliary subunit of native synaptic kainate receptors. J. Neurosci. 31, 10009-10018.
DOI
ScienceOn
|
52 |
Tek, C., Srihari, V. and Tek, E. (2008) Successful acamprosate treatment of alcohol dependence in schizophrenia. Schizophr. Res. 106, 373.
DOI
|
53 |
Fremeau, R. T. Jr, Burman, J., Qureshi, T., Tran, C. H., Proctor, J., Johnson, J., Zhang H., Sulzer D., Copenhagen, D. R., Storm- Mathisen, J., Reimer, R. J., Chaudhry, F. A. and Edwards, R. H. (2002) The identifi cation of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate. Proc. Natl. Acad. Sci. USA. 99, 14488-14493.
DOI
ScienceOn
|
54 |
Ehlers, M. D., Fung, E. T., O'Brien, R. J. and Huganir, R. L. (1998) Splice variant-specifi c interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments. J. Neurosci. 18, 720-730.
|
55 |
Evins, A. E., Amico, E., Posever, T. A., Toker, R. and Goff, D. C. (2002) D-Cycloserine added to risperidone in patients with primary negative symptoms of schizophrenia. Schizophr. Res. 56, 19-23.
DOI
|
56 |
Fell, M. J., Svensson, K. A., Johnson, B. G. and Schoepp, D. D. (2008) Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039). J. Pharmacol. Exp. Ther. 326, 209-217.
DOI
ScienceOn
|
57 |
Funk, A. J., Rumbaugh, G., Harotunian, V., McCullumsmith, R. E. and Meador-Woodruff, J. H. (2009) Decreased expression of NMDA receptor- associated proteins in frontal cortex of elderly patients with schizophrenia. Neuroreport. 20, 1019-1022.
DOI
ScienceOn
|
58 |
Galici, R., Echemendia, N. G., Rodriguez, A. L. and Conn, P. J. (2005) A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity. J. Pharmacol. Exp. Ther. 315, 1181-1187.
DOI
ScienceOn
|
59 |
Gama, C. S., Antunes, P., Moser, C. and Belmonte-de-Abreu, P. S. (2005) [Memantine as an adjunctive therapy for schizophrenia negative symptoms]. Rev. Bras. Psiquiatr. 27, 257-258.
|
60 |
Thomas, C., Carroll, B. T., Maley, R. T., Jayanti, K. and Koduri, A. (2005) Memantine and catatonic schizophrenia. Am. J. Psychiatry 162, 626.
|
61 |
Thomas, C. G., Miller, A. J. and Westbrook, G. L. (2006) Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons. J. Neurophysiol. 95, 1727-1734.
DOI
ScienceOn
|
62 |
Tiihonen, J., Halonen, P., Wahlbeck, K., Repo-Tiihonen, E., Hyvarinen, S., Eronen, M., Putkonen, H., Takala, P., Mehtonen, O. P., Puck, M., Oksanen, J., Koskelainen, P., Joffe, G., Aer, J., Hallikainen, T., Ryynanen, O. P. and Tupala, E. (2005) Topiramate add-on in treatment- resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial. J. Clin. Psychiatry 66, 1012-1015.
DOI
ScienceOn
|
63 |
Tingley, W. G., Roche, K. W., Thompson, A. K. and Huganir, R. L. (1993) Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain. Nature 364, 70-73.
DOI
|
64 |
Tingley, W. G., Ehlers, M. D., Kameyama, K,. Doherty, C., Ptak, J. B., Riley, C. T. and Huganir, R. L. (1997) Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-Daspartate receptor NR1 subunit using phosphorylation site-specificantibodies. J. Biol. Chem. 272, 5157-5166.
DOI
|
65 |
Tomita, S. (2010) Regulation of ionotropic glutamate receptors by their auxiliary subunits. Physiology (Bethesda) 25, 41-49.
DOI
ScienceOn
|
66 |
Toyooka, K., Iritani, S., Makifuchi, T., Shirakawa, O., Kitamura, N., Maeda, K., Nakamura, R., Niizato, K., Watanabe, M., Kakita, A., Takahashi, H., Someya, T. and Nawa, H. (2002) Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia. J. Neurochem. 83, 797-806.
DOI
ScienceOn
|
67 |
Tsai, G., Lane, H. Y., Yang, P., Chong, M. Y. and Lange, N. (2004) Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry 55, 452-456.
DOI
ScienceOn
|
68 |
Gesemann, M., Lesslauer, A., Maurer, C. M., Schonthaler, H. B. and Neuhauss, S. C. (2010) Phylogenetic analysis of the vertebrate excitatory/ neutral amino acid transporter (SLC1/EAAT) family reveals lineage specificsubfamilies. BMC Evol. Biol. 10, 117.
DOI
|
69 |
Gao, X. M., Sakai, K., Roberts, R. C., Conley, R. R., Dean, B. and Tamminga, C. A. (2000) Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am. J. Psychiatry 157, 1141-1149.
DOI
ScienceOn
|
70 |
Garey, L. J., Von Bussmann, K. A. and Hirsch, S. R. (2006) Decreased numerical density of kainate receptor-positive neurons in the orbitofrontal cortex of chronic schizophrenics. Exp. Brain Res. 173, 234-242.
DOI
ScienceOn
|
71 |
Ghose, S., Crook, J. M., Bartus, C. L., Sherman, T. G., Herman, M. M., Hyde, T. M., Kleinman, J. E. and Akil, M. (2008) Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia. Int. J. Neurosci. 118, 1609-1627.
DOI
ScienceOn
|
72 |
Ghose, S., Gleason, K. A., Potts, B. W., Lewis-Amezcua, K. and Tamminga, C. A. (2009) Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action? Am. J. Psychiatry 166, 812-820.
DOI
ScienceOn
|
73 |
Goff, D. C., Henderson, D. C., Evins, A. E. and Amico, E. (1999a) A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biol. Psychiatry. 45, 512-514.
DOI
ScienceOn
|
74 |
Goff, D. C., Herz, L., Posever, T., Shih, V., Tsai, G., Henderson, D. C., Freudenreich, O., Evins, A. E., Yovel, I., Zhang, H. and Schoenfeld, D. (2005) A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients. Psychopharmacology (Berl) 179, 144-150.
DOI
|
75 |
von Engelhardt, J., Mack, V., Sprengel, R., Kavenstock, N., Li, K. W., Stern-Bach, Y., Smit, A. B., Seeburg, P. H. and Monyer, H. (2010) CKAMP44: a brain-specifi c protein attenuating short-term synaptic plasticity in the dentate gyrus. Science 327, 1518-1522.
DOI
ScienceOn
|
76 |
Tsai, G. E., Yang, P., Chang, Y. C. and Chong, M. Y. (2006) D-alanine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry 59, 230-234.
DOI
ScienceOn
|
77 |
Tsai, G., Yang, P., Chung, L. C., Lange, N. and Coyle, J. T. (1998) D-serine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry 44, 1081-1089.
DOI
ScienceOn
|
78 |
Volk, D. W., Eggan, S. M. and Lewis, D. A. (2010) Alterations in metabotropic glutamate receptor 1alpha and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia. Am. J. Psychiatry 167, 1489-1498.
DOI
|
79 |
Vrajova, M., Stastny, F., Horacek, J., Lochman, J., Sery, O., Pekova, S., Klaschka, J. and Hoschl, C. (2010) Expression of the hippocampal NMDA receptor GluN1 subunit and its splicing isoforms in schizophrenia: postmortem study. Neurochem. Res. 35, 994-1002.
DOI
ScienceOn
|
80 |
Westphal, R. S., Tavalin, S. J., Lin, J. W., Alto, N. M., Fraser, I. D., Langeberg, L. K., Sheng, M. and Scott, J. D. (1999) Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. Science 285, 93-96.
DOI
|
81 |
Whiteheart, S. W. and Matveeva, E. A. (2004) Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor. J. Struct. Biol. 146, 32-43.
DOI
ScienceOn
|
82 |
Woo, T. U., Shrestha, K., Amstrong, C., Minns, M. M., Walsh, J. P. and Benes, F. M. (2007) Differential alterations of kainate receptor subunits in inhibitory interneurons in the anterior cingulate cortex in schizophrenia and bipolar disorder. Schizophr. Res. 96, 46-61.
DOI
ScienceOn
|
83 |
Goff, D. C., Tsai, G., Manoach, D. S., Flood, J., Darby, D. G. and Coyle, J. T. (1996) D-cycloserine added to clozapine for patients with schizophrenia. Am. J. Psychiatry 153, 1628-1630.
DOI
|
84 |
Goff, D. C., Lamberti, J. S., Leon, A. C., Green, M. F., Miller, A. L., Patel, J., Manschreck, T., Freudenreich, O. and Johnson, S. A. (2008) A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive defi cits in schizophrenia. Neuropsychopharmacology 33, 465-472.
DOI
ScienceOn
|
85 |
Goff, D. C., Leahy, L., Berman, I., Posever, T., Herz, L., Leon, A. C., Johnson, S. A. and Lynch, G. (2001) A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia. J. Clin. Psychopharmacol. 21, 484-487.
DOI
ScienceOn
|
86 |
Goff, D. C, Tsai, G., Levitt, J., Amico, E., Manoach, D., Schoenfeld, D. A., Hayden, D. L., McCarley, R. and Coyle, J. T. (1999b) A placebocontrolled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. Arch. Gen. Psychiatry 56, 21-27.
DOI
ScienceOn
|
87 |
Goff, D. C. and Wine, L. (1997) Glutamate in schizophrenia: clinical and research implications. Schizophr. Res. 27, 157-168.
DOI
|
88 |
Gonzalez-Maeso, J., Ang, R. L., Yuen, T., Chan, P., Weisstaub, N. V., Lopez-Gimenez, J. F., Zhou, M., Okawa, Y., Callado, L. F., Milligan, G., Gingrich, J. A., Filizola, M., Meana, J. J. and Sealfon, S. C. (2008) Identifi cation of a serotonin/glutamate receptor complex implicated in psychosis. Nature 452, 93-97.
DOI
ScienceOn
|
89 |
Granger, A. J., Gray, J. A., Lu, W. and Nicoll, R. A. (2011) Genetic analysis of neuronal ionotropic glutamate receptor subunits. J. Physiol. 589, 4095-4101.
DOI
|
90 |
Greger, I. H. and Esteban, J. A. (2007) AMPA receptor biogenesis and traffi cking. Curr. Opin. Neurobiol. 17, 289-297.
DOI
ScienceOn
|
91 |
Gupta, D. S., McCullumsmith, R. E., Beneyto, M., Haroutunian, V., Davis, K. L. and Meador-Woodruff, J. H. (2005) Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse 57, 123-131.
DOI
ScienceOn
|
92 |
Hashimoto, K., Fukaya, M., Qiao, X., Sakimura, K., Watanabe, M. and Kano, M. (1999) Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. J. Neurosci. 19, 6027-6036.
|
93 |
Yu, B., Wang, C., Liu, J., Johnson, K. M. and Gallagher, J. P. (2002) Adaptation to chronic PCP results in hyperfunctional NMDA and hypofunctional GABA(A) synaptic receptors. Neuroscience 113, 1-10.
DOI
ScienceOn
|
94 |
Zavitsanou, K., Ward, P. B. and Huang X. F. (2002) Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia. Neuropsychopharmacology 27, 826-833.
DOI
ScienceOn
|
95 |
Zhang, W., St-Gelais, F., Grabner, C. P., Trinidad, J. C., Sumioka, A., Morimoto-Tomita, M., Kim, K. S., Straub, C., Burlingame, A. L., Howe, J. R. and Tomita, S. (2009) A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron 61, 385-396.
DOI
ScienceOn
|
96 |
Hammond, J. C., McCullumsmith, R. E., Funk, A. J., Haroutunian, V. and Meador-Woodruff, J. H. (2010) Evidence for abnormal forward traffi cking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Neuropsychopharmacology 35, 2110-2119.
DOI
ScienceOn
|
97 |
Harrison, P. J., McLaughlin, D. and Kerwin, R. W. (1991) Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet. 337, 450-452.
DOI
ScienceOn
|
98 |
Hayashi, Y., Shi, S. H., Esteban, J. A., Piccini, A., Poncer, J. C., Malinow, R. (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287, 2262-2267.
DOI
ScienceOn
|
99 |
Healy, D. J., Haroutunian, V., Powchik, P., Davidson, M., Davis, K. L., Watson, S. J. and Meador-Woodruff, J. H. (1998) AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenics. Neuropsychopharmacology 19, 278-286.
DOI
|
100 |
Heresco-Levy, U. and Javitt, D. C. (2004) Comparative effects of glycine and D-cycloserine on persistent negative symptoms in schizophrenia: a retrospective analysis. Schizophr. Res. 66, 89-96.
DOI
ScienceOn
|
101 |
Heresco-Levy, U., Javitt, D. C., Ebstein, R., Vass, A., Lichtenberg, P., Bar, G., Catinari, S. and Ermilov, M. (2005) D-serine effi cacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia. Biol. Psychiatry. 57, 577-585.
DOI
ScienceOn
|
102 |
Hertzmann, M., Reba, R. C. and Kotlyarov, E. V. (1990) Single photon emission computed tomography in phencyclidine and related drug abuse. Am. J. Psychiatry 147, 255-256.
|
103 |
Hollmann, M. and Heinemann, S. (1994) Cloned glutamate receptors. Annu. Rev. Neurosci. 17, 31-108.
DOI
ScienceOn
|
104 |
Itil, T., Keskiner, A., Kiremitci, N. and Holden, J. M. (1967) Effect of phencyclidine in chronic schizophrenics. Can Psychiatr. Assoc. J. 12, 209-212.
|
105 |
Humphries, C., Mortimer, A., Hirsch, S. and de Belleroche, J. (1996) NMDA receptor mRNA correlation with antemortem cognitive impairment in schizophrenia. Neuroreport 7, 2051-2055.
DOI
ScienceOn
|
106 |
Ibrahim, H. M., Hogg, A. J. Jr., Healy, D. J., Haroutunian, V., Davis, K. L. and Meador-Woodruff, J. H. (2000) Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophrenia. Am. J. Psychiatry 157, 1811-1823.
DOI
ScienceOn
|
107 |
Imre, G. (2007) The preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268. CNS Drug Rev. 13, 444-464.
|
108 |
Javitt, D. C. (2002) Glycine modulators in schizophrenia. Curr. Opin. Investig. Drugs 3, 1067-1072.
|
109 |
Javitt, D. C. (1996) Glycine therapy of schizophrenia. Biol. Psychiatry 40, 684-686.
DOI
ScienceOn
|
110 |
Javitt, D. C. (2006) Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients. Curr. Opin. Psychiatry 19, 151-157.
DOI
ScienceOn
|
111 |
Javitt, D. C., Silipo, G., Cienfuegos, A., Shelley, A. M., Bark, N., Park, M., Lindenmayer, J. P., Suckow, R. and Zukin, S. R. (2001) Adjunctive high-dose glycine in the treatment of schizophrenia. Int. J. Neuropsychopharmacol. 4, 385-391.
|
112 |
Javitt, D. C. and Zukin, S. R. (1991) Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 148, 1301-1308.
DOI
|
113 |
Javitt, D. C., Zylberman, I., Zukin, S. R., Heresco-Levy, U., Lindenmayer, J. P. (1994) Amelioration of negative symptoms in schizophrenia by glycine. Am. J. Psychiatry 151, 1234-1236.
DOI
|
114 |
Kalashnikova, E., Lorca, R. A., Kaur, I., Barisone, G. A., Li, B., Ishimaru, T., Trimmer, J. S., Mohapatra, D. P. and Diaz, E. (2010) SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron 65, 80-93.
DOI
ScienceOn
|
115 |
Jentsch, J. D. and Roth, R. H. (1999) The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 20, 201-225.
DOI
ScienceOn
|
116 |
Jordan, G. R., McCulloch, J., Shahid, M., Hill, D. R., Henry, B. and Horsburgh, K. (2005) Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography. Neuropharmacology 49, 254-264.
DOI
ScienceOn
|
117 |
Joyce, J. N. and Meador-Woodruff, J. H. (1997) Linking the family of D2 receptors to neuronal circuits in human brain: insights into schizophrenia. Neuropsychopharmacology 16, 375-384.
DOI
ScienceOn
|
118 |
Kanai, Y., Smith, C. P. and Hediger, M. A. (1993) A new family of neurotransmitter transporters: the high-affi nity glutamate transporters. FASEB J. 7, 1450-1459.
|
119 |
Kanuma, K., Aoki, T. and Shimazaki, Y. (2010) Recent patents on positive allosteric modulators of the metabotropic glutamate 5 receptor as a potential treatment for schizophrenia. Recent Pat. CNS Drug Discov. 5, 23-34.
|
120 |
Kato, A. S., Gill, M. B., Yu, H., Nisenbaum, E. S. and Bredt, D. S. (2010) TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends Neurosci. 33, 241-248.
DOI
ScienceOn
|
121 |
Keifer, J. and Zheng, Z. (2010) AMPA receptor traffi cking and learning. Eur. J. Neurosci. 32, 269-277.
DOI
ScienceOn
|
122 |
Keinanen, K., Wisden, W., Sommer, B., Werner, P., Herb, A., Verdoorn, T. A., Sakmann, B. and Seeburg, P. H. (1990) A family of AMPAselective glutamate receptors. Science 249, 556-560.
DOI
|
123 |
Kristiansen, L. V., Beneyto, M., Haroutunian, V. and Meador-Woodruff, J. H. (2006) Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Mol. Psychiatry 11, 737-747, 705.
DOI
ScienceOn
|
124 |
Kerwin, R., Patel, S. and Meldrum, B. (1990) Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem. Neuroscience 39, 25-32.
DOI
ScienceOn
|
125 |
Kessels, H. W. and Malinow, R. (2009) Synaptic AMPA receptor plasticity and behavior. Neuron 61, 340-350.
DOI
ScienceOn
|
126 |
Kornhuber, J., Bormann, J., Retz, W., Hubers, M. and Riederer, P. (1989) Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex. Eur. J. Pharmacol. 166, 589-590.
DOI
ScienceOn
|
127 |
Kristiansen, L. V., Bakir, B., Haroutunian, V. and Meador-Woodruff, J. H. (2010a) Expression of the NR2B-NMDA receptor traffi cking complex in prefrontal cortex from a group of elderly patients with schizophrenia. Schizophr. Res. 119, 198-209.
DOI
|
128 |
Kristiansen, L. V., Patel, S. A., Haroutunian, V. and Meador-Woodruff, J. H. (2010b) Expression of the NR2B-NMDA receptor subunit and its Tbr-1/CINAP regulatory proteins in postmortem brain suggest altered receptor processing in schizophrenia. Synapse 64, 495-502.
DOI
ScienceOn
|
129 |
Krivoy, A., Weizman, A., Laor, L., Hellinger, N., Zemishlany, Z. and Fischel, T. (2008) Addition of memantine to antipsychotic treatment in schizophrenia inpatients with residual symptoms: A preliminary study. Eur. Neuropsychopharmacol. 18, 117-121.
DOI
ScienceOn
|
130 |
Krystal, J. H., Karper, L. P., Seibyl, J. P., Freeman, G. K., Delaney, R., Bremner, J. D., Heninger, G. R., Bowers, M. B. Jr. and Charney, D. S. (1994) Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch. Gen. Psychiatry 51, 199-214.
DOI
ScienceOn
|
131 |
Lane, H. Y., Liu, Y. C., Huang, C. L., Chang, Y. C., Liau, C. H., Perng, C. H. and Tsai, G. E. (2008) Sarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind study. Biol. Psychiatry 63, 9-12.
DOI
ScienceOn
|
132 |
Lahti, A. C., Holcomb, H. H., Medoff, D. R. and Tamminga, C. A. (1995) Ketamine activates psychosis and alters limbic blood fl ow in schizophrenia. Neuroreport 6, 869-872.
DOI
ScienceOn
|
133 |
Lane, H. Y., Chang, Y. C., Liu, Y. C., Chiu, C. C. and Tsai, G. E. (2005) Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. Arch. Gen. Psychiatry 62, 1196-1204.
DOI
ScienceOn
|
134 |
Lane, H. Y., Lin, C. H., Huang, Y. J., Liao, C. H., Chang, Y. C. and Tsai, G. E. (2010) A randomized, double-blind, placebo-controlled comparison study of sarcosine (N-methylglycine) and D-serine add-on treatment for schizophrenia. Int. J. Neuropsychopharmacol. 13, 451-460.
DOI
|
135 |
Lane, H. Y., Huang, C. L., Wu, P. L., Liu, Y. C., Chang, Y. C., Lin, P. Y., Chen, P. W. and Tsai, G. (2006) Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia. Biol. Psychiatry 60, 645-649.
DOI
ScienceOn
|
136 |
Laruelle, M., Abi-Dargham, A., Gil, R., Kegeles, L. and Innis, R. (1999) Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol. Psychiatry 46, 56-72.
DOI
ScienceOn
|
137 |
Lau, C. G. and Zukin, R. S. (2007) NMDA receptor traffi cking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 8, 413-426.
|
138 |
Lavezzari, G., McCallum, J., Dewey, C. M. and Roche, K. W. (2004) Subunit-specifi c regulation of NMDA receptor endocytosis. J. Neurosci. 24, 6383-6391.
DOI
ScienceOn
|
139 |
Le Corre, S., Harper, C. G., Lopez, P., Ward, P. and Catts, S. (2000) Increased levels of expression of an NMDARI splice variant in the superior temporal gyrus in schizophrenia. Neuroreport 11, 983-986.
DOI
ScienceOn
|
140 |
Lehre, K. P., Levy, L. M., Ottersen, O. P., Storm-Mathisen, J. and Danbolt, N. C. (1995) Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J. Neurosci. 15, 1835-1853.
|
141 |
Lerma, J. (2003) Roles and rules of kainate receptors in synaptic transmission. Nat. Rev. Neurosci. 4, 481-495.
DOI
ScienceOn
|
142 |
Letts, V. A, Felix, R., Biddlecome, G. H., Arikkath, J., Mahaffey, C. L., Valenzuela, A., Bartlett, F. S., 2nd, Mori, Y., Campbell, K. P. and Frankel, W. N. (1998) The mouse stargazer gene encodes a neuronal -channel gamma subunit. Nat. Genet. 19, 340-347.
DOI
ScienceOn
|
143 |
Li, D., Specht, C. G., Waites, C. L., Butler-Munro, C., Leal-Ortiz, S., Foote, J. W., Genoux, D., Garner, C. C. and Montgomery, J. M. (2011) SAP97 directs NMDA receptor spine targeting and synaptic plasticity. J. Physiol. 589, 4491-4510.
DOI
|
144 |
Lieberman, J. A., Papadakis, K., Csernansky, J., Litman, R., Volavka, J., Jia, X. D. and Gage, A. (2009) A randomized, placebo-controlled study of memantine as adjunctive treatment in patients with schizophrenia. Neuropsychopharmacology 34, 1322-1329.
DOI
ScienceOn
|
145 |
Lin, J. W., Wyszynski, M., Madhavan, R., Sealock, R., Kim, J. U. and Sheng, M. (1998) Yotiao, a novel protein of neuromuscular junction and brain that interacts with specifi c splice variants of NMDA receptor subunit NR1. J. Neurosci. 18, 2017-2027.
|
146 |
Lu, W. and Ziff, E. B. (2005) PICK1 interacts with ABP/GRIP to regulate AMPA receptor traffi cking. Neuron. 47, 407-421.
DOI
ScienceOn
|
147 |
Mah, S. J., Cornell, E., Mitchell, N. A. and Fleck, M. W. (2005) Glutamate receptor traffi cking: endoplasmic reticulum quality control involves ligand binding and receptor function. J. Neurosci. 25, 2215-2225.
DOI
ScienceOn
|
148 |
Malinow, R. and Malenka, R. C. (2002) AMPA receptor traffi cking and synaptic plasticity. Annu. Rev. Neurosci. 25, 103-126.
DOI
ScienceOn
|
149 |
Aihara, Y., Mashima, H., Onda, H., Hisano, S., Kasuya, H., Hori, T., Yamada, S., Tomura, H., Yamada, Y., Inoue, I., Kojima, I. and Takeda, J. (2000) Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter. J. Neurochem. 74, 2622-2625.
|
150 |
Aanonsen, L. M. and Wilcox, G. L. (1986) Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice. Neurosci. Lett. 67, 191-197.
DOI
ScienceOn
|
151 |
Akbarian, S., Sucher, N. J., Bradley, D., Tafazzoli, A., Trinh, D., Hetrick, W. P., Potkin, S. G., Sandman, C. A., Bunney, W. E. Jr. and Jones, E. G. (1996) Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics. J. Neurosci. 16, 19-30.
|
152 |
Anggono, V., Clem, R. L. and Huganir, R. L. (2011) PICK1 loss of function occludes homeostatic synaptic scaling. J. Neurosci. 31, 2188-2196.
DOI
ScienceOn
|
153 |
Arai, A., Kessler, M., Rogers, G. and Lynch G. (1996) Effects of a memory-enhancing drug on DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor currents and synaptic transmission in hippocampus. J. Pharmacol. Exp. Ther. 278, 627-638.
|
154 |
Meador-Woodruff, J. H., Hogg, A. J. Jr. and Smith, R. E. (2001b) Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder. Brain Res. Bull. 55, 631-640.
DOI
ScienceOn
|
155 |
Masson, J., Sagne, C., Hamon, M. and El Mestikawy, S. (1999) Neurotransmitter transporters in the central nervous system. Pharmacol. Rev. 51, 439-464.
|
156 |
McCullumsmith, R. E., Kristiansen, L. V., Beneyto, M., Scarr, E., Dean, B. and Meador-Woodruff J. H. (2007) Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder. Brain Res. 1127, 108-118.
DOI
|
157 |
Meador-Woodruff, J. H., Davis, K. L. and Haroutunian, V. (2001a) Abnormal kainate receptor expression in prefrontal cortex in schizophrenia. Neuropsychopharmacology 24, 545-552.
DOI
ScienceOn
|
158 |
Milton, I. D., Banner, S. J., Ince, P. G., Piggott, N. H., Fray, A. E., Thatcher, N., Horne, C. H. and Shaw, P. J. (1997) Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study. Brain Res. Mol. Brain Res. 52, 17-31.
DOI
|
159 |
Mirnics, K., Middleton, F. A., Marquez, A., Lewis, D. A. and Levitt, P. (2000) Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 28, 53-67.
DOI
ScienceOn
|
160 |
Moghaddam, B. and Adams, B. W. (1998) Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science 281, 1349-1352.
DOI
|
161 |
Moghaddam, B., Adams, B., Verma, A. and Daly, D. (1997) Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 17, 2921-2927.
|
162 |
Bats, C., Groc, L. and Choquet, D. (2007) The interaction between Stargazin and PSD-95 regulates AMPA receptor surface traffi cking. Neuron 53, 719-734.
DOI
ScienceOn
|
163 |
Araque, A., Parpura V., Sanzgiri R. P. and Haydon P. G. (1999) Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci. 22, 208-215.
DOI
ScienceOn
|
164 |
Arvanov, V. L. and Wang, R. Y. (1999) Clozapine, but not haloperidol, prevents the functional hyperactivity of N-methyl-D-aspartate receptors in rat cortical neurons induced by subchronic administration of phencyclidine. J. Pharmacol. Exp. Ther. 289, 1000-1006.
|
165 |
Bar-Peled, O., Ben-Hur, H., Biegon, A., Groner, Y., Dewhurst, S., Furuta, A. and Rothstein J. D. (1997) Distribution of glutamate transporter subtypes during human brain development. J. Neurochem. 69, 2571-2580.
|
166 |
Bellocchio, E. E., Reimer, R. J., Fremeau, R. T. Jr. and Edwards, R. H. (2000) Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter. Science 289, 957-960.
DOI
|
167 |
Benes, F. M., Todtenkopf, M. S. and Kostoulakos, P. (2001) GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives. Hippocampus 11, 482-491.
DOI
ScienceOn
|
168 |
Beneyto, M., Kristiansen, L. V., Oni-Orisan, A., McCullumsmith, R. E. and Meador-Woodruff J. H. (2007) Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders. Neuropsychopharmacology 32, 1888-1902.
DOI
ScienceOn
|
169 |
Beneyto, M. and Meador-Woodruff, J. H. (2006) Lamina-specifi c abnormalities of AMPA receptor traffi cking and signaling molecule transcripts in the prefrontal cortex in schizophrenia. Synapse 60, 585-598.
DOI
ScienceOn
|
170 |
Beneyto, M. and Meador-Woodruff, J. H. (2008) Lamina-specifi c abnormalities of NMDA receptor-associated postsynaptic protein transcripts in the prefrontal cortex in schizophrenia and bipolar disorder. Neuropsychopharmacology 33, 2175-2186.
DOI
ScienceOn
|
171 |
Nagao, S., Kwak, S. and Kanazawa, I. (1997) EAAT4, a glutamate transporter with properties of a chloride channel, is predominantly localized in Purkinje cell dendrites, and forms parasagittal compartments in rat cerebellum. Neuroscience 78, 929-933.
DOI
ScienceOn
|
172 |
Mueller, H. T., Haroutunian, V., Davis, K. L. and Meador-Woodruff, J. H. (2004) Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophrenia. Brain Res. Mol. Brain Res. 121, 60-69.
DOI
|
173 |
Mueller, H. T. and Meador-Woodruff, J. H. (2004) NR3A NMDA receptor subunit mRNA expression in schizophrenia, depression and bipolar disorder. Schizophr. Res. 71, 361-370.
DOI
ScienceOn
|
174 |
Naassila, M., Hammoumi, S., Legrand, E., Durbin, P. and Daoust, M. (1998) Mechanism of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain. Alcohol. Clin. Exp. Res. 22, 802-809.
DOI
ScienceOn
|
175 |
Neuhauss, S. C., Rico, E. P. and Gesemann, M. (2010) Nomenclature of glutamate transporters in zebrafi sh and other vertebrates. Brain Res. Bull. 83, 297.
DOI
ScienceOn
|
176 |
Newell, K. A., Zavitsanou, K. and Huang, X. F. (2005) Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patients. Neuroreport 16, 1363-1367.
DOI
ScienceOn
|
177 |
Ng, D., Pitcher, G. M., Szilard, R. K., Sertie, A., Kanisek, M., Clapcote, S. J., Lipina, T., Kalia, L. V., Joo, D., McKerlie, C., Cortez, M., Roder, J. C., Salter, M. W. and McInnes, R. R. (2009) Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol. 7, e41.
DOI
|
178 |
Ni, Y., Malarkey, E. B. and Parpura, V. (2007) Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons. J. Neurochem. 103, 1273-1284.
DOI
ScienceOn
|
179 |
Bettler, B., Boulter, J., Hermans-Borgmeyer, I., O'Shea-Greenfi eld, A., Deneris, E. S., Moll, C., Borgmeyer, U., Hollmann, M. and Heinemann, S. (1990) Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development. Neuron 5, 583-595.
DOI
ScienceOn
|
180 |
Bergeron, R., Meyer, T. M., Coyle, J. T. and Greene, R.W. (1998) Modulation of N-methyl-D-aspartate receptor function by glycine transport. Proc. Natl. Acad. Sci. USA. 95, 15730-15734.
DOI
ScienceOn
|
181 |
Bleakman, D. and Lodge, D. (1998) Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 37, 1187-1204.
DOI
ScienceOn
|
182 |
Boulter, J., Hollmann, M., O'Shea-Greenfi eld, A., Hartley, M., Deneris, E., Maron, C. and Heinemann, S. (1990) Molecular cloning and functional expression of glutamate receptor subunit genes. Science 249, 1033-1037.
DOI
|
183 |
Bredt, D. S. and Nicoll, R. A. (2003) AMPA receptor traffi cking at excitatory synapses. Neuron 40, 361-379.
DOI
ScienceOn
|
184 |
Breese, C. R., Freedman, R. and Leonard, S. S. (1995) Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain Res. 674, 82-90.
DOI
ScienceOn
|
185 |
Buchanan, R. W. and Carpenter, W. T. (2000) Schizophrenia: Introduction and Overview. In Comprehensive Textbook of Psychiatry, 7th Edition (B. J. Sadock, V. A. Sadock, Eds), pp. 1096-1110. Lippincott, Williams, and Wilkins, Philadelphia.
|
186 |
Buchanan, R. W., Javitt, D. C., Marder, S. R., Schooler, N. R., Gold, J. M., McMahon, R. P., Heresco-Levy, U. and Carpenter, W. T. (2007) The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the effi cacy of glutamatergic agents for negative symptoms and cognitive impairments. Am. J. Psychiatry 164, 1593-1602.
DOI
ScienceOn
|
187 |
Carpenter, S. S., Hatchett, A. D. and Fuller, M. A. (2006) Catatonic schizophrenia and the use of memantine. Ann. Pharmacother. 40, 344-346.
DOI
ScienceOn
|
188 |
Noga, J. T., Hyde, T. M., Herman, M. M., Spurney, C. F., Bigelow, L. B., Weinberger, D. R. and Kleinman, J. E. (1997) Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains. Synapse 27, 168-176.
DOI
ScienceOn
|
189 |
Nishikawa, T., Takashima, M. and Toru, M. (1983) Increased [3H]kainic acid binding in the prefrontal cortex in schizophrenia. Neurosci. Lett. 40, 245-250.
DOI
ScienceOn
|
190 |
Noebels, J. L., Qiao, X., Bronson, R. T., Spencer, C. and Davisson, M. T. (1990) Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy. Res. 7, 129-135.
DOI
ScienceOn
|
191 |
Noga, J. T. and Wang, H. (2002) Further postmortem autoradiographic studies of AMPA receptor binding in schizophrenia. Synapse 45, 250-258.
DOI
ScienceOn
|
192 |
Noorbala, A. A., Akhondzadeh, S., Davari-Ashtiani, R. and Amini- Nooshabadi, H. (1999) Piracetam in the treatment of schizophrenia: implications for the glutamate hypothesis of schizophrenia. J. Clin. Pharm. Ther. 24, 369-374.
DOI
ScienceOn
|
193 |
Ohnuma, T., Augood, S. J., Arai, H., McKenna, P. J. and Emson, P. C. (1998) Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain Res. Mol. Brain Res. 56, 207-217.
DOI
|
194 |
Ohtsuki, T., Toru, M. and Arinami, T. (2001) Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia. Psychiatr. Genet. 11, 79-83.
DOI
ScienceOn
|
195 |
Olive, M. F. (2009) Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr. Drug Abuse. Rev. 2, 83-98.
DOI
ScienceOn
|
196 |
Paz, R. D., Tardito, S., Atzori, M. and Tseng, K. Y. (2008) Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology. Eur. Neuropsychopharmacol. 18, 773-786.
DOI
ScienceOn
|
197 |
Chen, L., El-Husseini, A., Tomita, S., Bredt, D. S. and Nicoll, R. A. (2003) Stargazin differentially controls the traffi cking of alpha-amino- 3-hydroxyl-5-methyl-4-isoxazolepropionate and kainate receptors. Mol. Pharmacol. 64, 703-706.
DOI
ScienceOn
|
198 |
Carroll, B. T., Thomas, C. and Jayanti, K. (2006) Amantadine and memantine in catatonic schizophrenia. Ann. Clin. Psychiatry. 18, 133-134.
DOI
ScienceOn
|
199 |
Chaki, S. (2010) Group II metabotropic glutamate receptor agonists as a potential drug for schizophrenia. Eur. J. Pharmacol. 639, 59-66.
DOI
|
200 |
Chaki, S. and Hikichi, H. (2011) Targeting of metabotropic glutamate receptors for the treatment of schizophrenia. Curr. Pharm. Des. 17, 94-102.
DOI
ScienceOn
|
201 |
Chen, L., Chetkovich, D. M., Petralia, R. S., Sweeney, N. T., Kawasaki, Y., Wenthold, R. J., Bredt, D. S. and Nicoll, R. A. (2000) Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature 408, 936-943.
DOI
ScienceOn
|
202 |
Chung, H. J., Huang, Y. H., Lau, L. F. and Huganir, R. L. (2004) Regulation of the NMDA receptor complex and traffi cking by activitydependent phosphorylation of the NR2B subunit PDZ ligand. J. Neurosci. 24, 10248-10259.
DOI
ScienceOn
|
203 |
Citri, A., Bhattacharyya, S., Ma, C., Morishita, W., Fang, S., Rizo, J. and Malenka, R. C. (2010) Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying longterm depression. J. Neurosci. 30, 16437-16452.
DOI
ScienceOn
|
204 |
Clem, R. L., Anggono, V. and Huganir, R. L. (2010) PICK1 regulates incorporation of calcium-permeable AMPA receptors during cortical synaptic strengthening. J. Neurosci. 30, 6360-6366.
DOI
ScienceOn
|
205 |
Clinton, S. M., Haroutunian, V., Davis, K. L. and Meador-Woodruff J. H. (2003) Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophrenia. Am. J. Psychiatry 160, 1100-1109.
DOI
ScienceOn
|
206 |
Ralevski, E., O'Brien, E., Jane, J. S., Dean, E., Dwan, R. and Petrakis, I. (2011) Effects of acamprosate on cognition in a treatment study of patients with schizophrenia spectrum disorders and comorbid alcohol dependence. J. Nerv. Ment. Dis. 199, 499-505.
DOI
ScienceOn
|
207 |
Porter, R. H., Eastwood, S. L. and Harrison, P. J. (1997) Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Res. 751, 217-231.
DOI
ScienceOn
|
208 |
Prybylowski, K., Chang, K., Sans, N. and Kan, L., Vicini S., Wenthold R. J. (2005) The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2. Neuron 47, 845-857.
DOI
ScienceOn
|
209 |
Ratnam, J. and Teichberg, V. I. (2005) Neurofi lament-light increases the cell surface expression of the N-methyl-D-aspartate receptor and prevents its ubiquitination. J. Neurochem. 92, 878-885.
DOI
ScienceOn
|
210 |
Rao, A. and Craig, A. M. (1997) Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons. Neuron 19, 801-812.
DOI
ScienceOn
|
211 |
Richardson-Burns, S. M., Haroutunian, V., Davis, K. L., Watson, S. J. and Meador-Woodruff, J. H. (2000) Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus. Biol. Psychiatry 47, 22-28.
DOI
ScienceOn
|
212 |
Rico, E. P., de Oliveira, D. L., Rosemberg, D. B., Mussulini, B. H., Bonan, C. D., Dias, R. D., Wofchuk, S., Souza, D. O. and Bogo, M. R. (2010) Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafi sh brain. Brain Res. Bull. 81, 517-523.
DOI
ScienceOn
|
213 |
Rosse, R. B., Schwartz, B. L., Davis, R. E. and Deutsch, S. I. (1991) An NMDA intervention strategy in schizophrenia with "low-dose" milacemide. Clin. Neuropharmacol. 14, 268-272.
DOI
ScienceOn
|