• International Journal of Oral Biology
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• 제37권3호
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• pp.121-129
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• 2012

Previous clinical studies have demonstrated that gabapentin, a drug that binds to the voltage-gated calcium channel ${\alpha}2{\delta}1$ subunit proteins, is effective in the management of neuropathic pain, but there is limited evidence that addresses the participation of glial cells in the antiallodynic effects of this drug. The present study investigated the participation of glial cells in the anti-nociceptive effects of gabapentin in rats with trigeminal neuropathic pain produced by mal-positioned dental implants. Under anesthesia, the left mandibular second molar was extracted and replaced by a miniature dental implant to induce injury to the inferior alveolar nerve. Mal-positioned dental implants significantly decreased the air-puff thresholds both ipsilateral and contralateral to the injury site. Gabapentin was administered intracisternally beginning on postoperative day (POD) 1 or on POD 7 for three days. Early or late treatment with 0.3, 3, or 30 ${\mu}g$ of gabapentin produced significant anti-allodynic effect in the rats with mal-positioned dental implants. On POD 9, in the mal-positioned dental implants group, OX-42, a microglia marker, and GFAP, an astrocyte marker, were found to be up-regulated in the medullary dorsal horn, compared with the naive group. However, the intracisternal administration of gabapentin (30 ${\mu}g$) failed to reduce the number of activated microglia or astrocytes in the medullary dorsal horn. These findings suggest that gabapentin produces significant antinociceptive effects, which are not mediated by the inhibition of glial cell function in the medullary dorsal horn, in a rat model of trigeminal neuropathic pain.

• 생물환경조절학회지
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• 제22권1호
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• pp.61-64
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• 2013

본 연구는 오크라 종자를 볶았을 때의 기능성을 성분을 분석하여 용도 다양화를 위한 볶음차로의 이용 가능성을 검토하기 위하여 수행하였다. 꼬투리 당 오크라 종자의 수는 '그린소드' 품종이 78개, '베니' 품종이 88개 이었고, 과실 당 종자무게는 각각 4.4g과 6.3g이었다. 볶은 오크라 종자의 유리아미노산 함량은 $2.69mg{\cdot}g^{-1}$으로 생체종자의 $0.31mg{\cdot}g^{-1}$에 비해 8.7배나 높은 함량을 나타내었다. 총 페놀성 화합물 함량은 볶은 오크라 종자가 12.61mg CGA로 서 생체 상태보다 5배 높은 함량을 나타내었다. 오크라 종자의 항산화 활성은 DPPH 및 ABTS의 경우 볶은 오크라 종자가 생체 상태의 오크라 종자 보다 약 2배 이상 월등히 높게 나타내었다.

• 한국대기환경학회지
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• 제8권1호
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• pp.13-19
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• 1992

This study was conducted to determine the efficacy of using uniconazole,[(E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazole-1-yl)-1-penten-3-ol)] as a phytoprotectant against $SO_2$ injury in snap been (Phaseolus vulgaris L. 'Strike'). Thirteen days prior to $SO_2$ fumigation, plants were given a 100 ml soil drench of uniconazole solution at concentrations of 0.02, 0.10, 0.25 and 0.50 mg/pot. All four uniconazole concentrations were significantly effective in providing protection against $SO_2$ exposure(3 h at 1.5 ppm), but uniconazole treatment above 0.02 mg/pot severely reduced stem elongation, leaf enlargement, flowering date and pod number and weight. Uniconazole treatment had little or no effect on stomatal conductance but reduced transpiration rate on a whole plant basis by nearly 40%. This may reflect an alteration in canopy structure by reducing stem elongation and leaf enlargement. Although uniconazole did not increase the activities of superoxide dismutase(SOD) and peroxidase(POD) in non-$SO_2$-fumigated plants, it significantly increased those enzyme activities in $SO_2$-fumigated plants. Chlorophyll concentration on the basis of unit area was increased 50-60% by uniconazole. However, the difference was not detected on the basis of dry weight. $SO_2$ increased variable chlorophyll fluorescence (Fv) 48% after 1.5 h of exposure in non-uniconazole treated plants but decreased Fv in the plants after 3 h of exposure. By appliing uniconazole, it was possible to maintain high Fv values in the latter group of plants. These results suggest that the phytoprotective effects of uniconazole are related to its growth-retarding properties as an anti-gibberellin as well as the increase of activites of free radical scavengers such as SOD and POD.

• 한국육종학회지
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• 제41권1호
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• pp.36-39
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• 2009

녹두 신품종 "다현"은 전남11호와 AV-1-3-34-2를 작물과 학원에서 인공교배하고 전라남도농업기술원에서 2006년에 육성되었다. "다현"의 생육습성은 직립, 잎 모양은 심장형, 백축색은 녹색, 성숙기에 꼬투리는 검고 곧으며, 종피는 광택이 없는 녹색이다. 개체당협수는 21.0개로 표준품종인 "어울녹두"보다 4.0개 많고, 경장은 57 cm, 천립중은 48 g, 나물수율은 표준품종보다 5% 많다. "다현"의 바이러스, 갈색무늬병, 흰가루병 및 도복에 대한 포장저항성은 강하고 평균 수량은 1.90 ton/ha으로 표준품종보다 17% 많다.

• 대한통합의학회지
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• 제9권4호
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• pp.71-83
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• 2021

Purpose : This study compared the differences in power and agility of athletes in each sports using visual response speed test (VRST) scores after conducting 10 weeks of body stability exercise (BSE) on elementary school athletes in handball, football, volleyball and conducted a post-hoc test on the measured values. The subjects of this study were baseball (n=27), taekwondo (n=22), and football (n=23) athletes with at least two years of athletic experience. A total of 72 elementary school athletes were measured by VRST after 10 weeks of BSE under the same conditions. Methods : For VRST measurement of the upper extremity, the right and left hands were alternately touched in the order the blazepod equipment lights were turned on. The number of touches for 15 seconds and response touch were measured. In the case of the measurement of lower extremity the left lower extremity was measured first when the Blaze pod equipment light came on. The average value was obtained by measuring 3 times using a measurement sensor with the position indicated in order to measure the upper arms and legs the same. Results : This study confirmed homogeneity among sports and that VRST improved after implementing BSE for sports. However, no statistically significant difference was identified when comparing VRST improvements between sports, and post-hoc test results showed no significant differences either. Conclusion : After applying the BSE program under the same conditions for 10 weeks to elementary school students who can improve their power and agility the most, the results of the examination using the Blaze pod showed that the power and agility of baseball, taekwondo, and soccer players were similarly improved. From the fact that there was no significant difference among sports, it could be inferred that the BES training program could improve VRST without being limited to some sports.

• Nuclear Engineering and Technology
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• 제54권5호
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• pp.1825-1834
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• 2022

Performing high-fidelity computational fluid dynamics (HF-CFD) to predict the flow and heat transfer state of the coolant in the reactor core is expensive, especially in scenarios that require extensive parameter search, such as uncertainty analysis and design optimization. This work investigated the performance of utilizing a multi-fidelity reduced-order model (MF-ROM) in PWR rod bundles simulation. Firstly, basis vectors and basis vector coefficients of high-fidelity and low-fidelity CFD results are extracted separately by the proper orthogonal decomposition (POD) approach. Secondly, a surrogate model is trained to map the relationship between the extracted coefficients from different fidelity results. In the prediction stage, the coefficients of the low-fidelity data under the new operating conditions are extracted by using the obtained POD basis vectors. Then, the trained surrogate model uses the low-fidelity coefficients to regress the high-fidelity coefficients. The predicted high-fidelity data is reconstructed from the product of extracted basis vectors and the regression coefficients. The effectiveness of the MF-ROM is evaluated on a flow and heat transfer problem in PWR fuel rod bundles. Two data-driven algorithms, the Kriging and artificial neural network (ANN), are trained as surrogate models for the MF-ROM to reconstruct the complex flow and heat transfer field downstream of the mixing vanes. The results show good agreements between the data reconstructed with the trained MF-ROM and the high-fidelity CFD simulation result, while the former only requires to taken the computational burden of low-fidelity simulation. The results also show that the performance of the ANN model is slightly better than the Kriging model when using a high number of POD basis vectors for regression. Moreover, the result presented in this paper demonstrates the suitability of the proposed MF-ROM for high-fidelity fixed value initialization to accelerate complex simulation.

• 한국작물학회지
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• 제51권7호
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• pp.584-592
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• 2006

본 연구는 나물용 콩의 파종기가 콩나물 원료콩의 수량구성요소 및 수량에 미치는 영향을 구명함으로써 양질 콩나물 품종육성과 콩나물 원료콩의 안정적 생산 공급을 위한 기초 자료를 얻고자 $2000{\sim}2001$년에 호남농업연구소 전작시험 포장에서 파종시기 시험을 수행하였던 결과를 요약하면 다음과 같다. 1. 개체당 협수, 공협수, 입수 및 100립중은 파종기 및 품종간에 차이가 있었으며, 파종기가 늦어짐에 따라 감소하였다. 협당 입수별 협수의 분포비율은 $2{\sim}3$립 협이 $80.9{\sim}77.5%$이었으며 파종기에 따라 2립 협의 변이가 컸다. 2. 수량은 2년간 시험품종 평균 5월 25일 파종은 290 kg/10a, 6월 15일 파종은 269 kg/10a 및 7월 5일 파종은 221 kg/10a으로 파종기가 늦어질수록 감소하였고, 풍산나물콩이 수량이 가장 높았으며 파종기에 따른 수량 감소 정도가 적었고 그 외 품종들은 파종기에 따른 수량의 감소 정도가 컸다. 3. 수량은 개화일수, 성숙일수, 생육일수, 분지수, 줄기굵기, 개체당 협수, 개체당 입수 및 개체당 엽면적과 정의 상관이었으며 개체당 협수는 개체당 입수, 개체당 엽면적 및 건물중과, 개체당 입수는 개체당 엽면적 및 건물중과 정의 상관이었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2005년도 창립60주년 기념 추계 학술대회
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• pp.79.1-79.1
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• 2005

• Wind and Structures
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• 제25권5호
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• pp.493-506
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• 2017

Wind-induced response behavior of long-span roof structures is very complicated, showing significant contributions of multiple vibration modes. The largest load effects in a huge number of members should be considered for the sake of the equivalent static wind loads (ESWLs). Studies on essential matters and necessary conditions of the universal ESWLs are discussed. An efficient method for universal ESWLs on long-span roof structures is proposed. The generalized resuming forces including both the external wind loads and inertial forces are defined. Then, the universal ESWLs are given by a combination of eigenmodes calculated by proper orthogonal decomposition (POD) analysis. Firstly, the least squares method is applied to a matrix of eigenmodes by using the influence function. Then, the universal ESWLs distribution is obtained which reproduces the largest load effects simultaneously. Secondly, by choosing the eigenmodes of generalized resuming forces as the basic loading distribution vectors, this method becomes efficient. Meanwhile, by using the constraint equations, the universal ESWLs becomes reasonable. Finally, reproduced largest load effects by load-response-correlation (LRC) ESWLs and universal ESWLs are compared with the actual largest load effects obtained by the time domain response analysis for a long-span roof structure. The results demonstrate the feasibility and usefulness of the proposed universal ESWLs method.

• 한국가시화정보학회지
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• 제15권2호
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• pp.59-67
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• 2017

To verify floatability of ABB (Air bubble barrier), we compared bubble swarm behavior with and without the air-driven ejector. Experiment was conducted using the fabricated air-driven ejector with 5 mm nozzle on the bottom of 1 m3 water tank. Reynolds number of air in the nozzle was ranged 1766-13248. We analyzed data with statistical method using image processing, particle mage velocimetry (PIV) and proper orthogonal decomposition (POD) analysis. As a result of POD analysis, there was no significant eigenmode in bubbly flow generated from the ejector. It means that more complex turbulent flows were formed by the ejector, thereby (1) making bubbles finer, (2) promoting three-dimensional energy transfer between bubble and water, and (3) making evenly distributed velocity profile of water. It is concluded that the air-driven ejector could enhance the performance of ABB.