• 한국임상보건과학회지
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• 제8권2호
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• pp.1436-1443
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• 2020

Purpose: The purpose of this study was to differences in the expression rate of Porphyromonas gingivalis according to smoking status, smoking amount and period of smoking. Methods: At the time of investigation, 30 smokers and non-smokers were recruited among patients with periodontitis with a probing pocket depth(PPD) of 4 mm or more. General information was collected using a self-questionnaire, and the average value was used by a dentist to measure the probing pocket depth of three times each for the first or second molar. Plaque collection and analysis were performed by collecting only subgingival plaque using a conventional method, and the expression rate of P. gingivalis was confirmed using polymerase chain reaction (PCR). For statistical analysis, the SPSS Ver 25.0 program was used. Results: Smoking did not have a significant effect on the expression of P. gingivalis, but it did affect the expression of more type II genotypes (p<0.05). In addition, smokers had more slight periodontal pocket, and the amount and duration of smoking did not affect the expression of P. gingivalis. Conclusions: In the future, it is necessary to reinforce the group of smokers and non-smokers with healthy oral conditions, and to investigate the quantitative difference in the expression rate and genotype of P. gingivalis over time of harmful substances in smoking.

• 대한토목학회논문집
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• 제26권5A호
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• pp.817-822
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• 2006

프리캐스트 바닥판들의 이음부에 발생하는 교축방향 인장응력을 제어하고, 이음부의 누수 등을 방지하기 위하여 교축 방향으로 프리스트레스를 도입한다. 효과적인 압축력 도입을 위하여 합성 전에 프리캐스트 바닥판에 압축력을 도입한다. 이때 프리캐스트 바닥판에 존재하는 전단포켓으로 인하여 바닥판에 균일한 압축력 도입이 어렵고, 전단포켓의 주변 콘크리트에 국부적인 응력집중이 발생한다. 따라서 본 연구에서는 상용 구조해석 프로그램을 이용하여 서로 다른 4가지 형상의 전단포켓을 갖는 프리캐스트 바닥판에 대하여 유한요소해석을 수행하였다. 그 결과 전단포켓의 모서리 부분이 원형인 전단포켓이 응력집중이 가장 작은 것으로 나타났다.

• 농촌의학ㆍ지역보건
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• 제33권2호
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• pp.181-192
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• 2008

Objective: The use of complementary and alternative medicine (CAM) is common especially among patients with osteoarthritis The aim of this study was to investigate the utilization rate and expenditures of patients who use CAM. Method: Two hundred seventy four patients with osteoarthritis were interviewed by a telephone survey. A structured questionnaire about sociodemographic features and type, cost, satisfaction and reason of CAM utilization was used Results: Among 274 patients with osteoarthritis, 251 patients(91.6%) had used at least one type of CAM during six months. There was a significant difference in sex (female), age (70 years), medical security (insurance), educational level between the user and non-user of CAM. Hyperthermia was the most use. The average cost for CAM utilization was 120 thousands won/person during six months and there was no difference in sociodemographic features among the out-of-pocket cost of users. The scores of satisfaction for CAM use were ranged between 60-70. Conclusions: CAM became a popular source of health care because of elderly and lay referral system. And Korean spent a substantial amount of out-of-pocket money on CAM without benefit. Health care system and professionals should pay more attention to CAM, make a evidence for CAM.

• 대한토목학회논문집
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• 제28권6C호
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• pp.321-329
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• 2008

본 연구에서는 전통적인 압밀촉진공법의 단점을 보완하기 위한 방법으로 석션보드드레인 공법을 제안하고, 본 공법의 개량특성을 파악하기 위해, 배수재 종류 및 단계 진공압 조건에 따른 일련의 Column 실험을 실시하였다. 이때 실험 간 발생되는 침하량과 실험 종료 후 발생된 함수비 저감효과 및 강도증진효과를 파악하고, 개량 기간에 따른 압밀도를 파악하여 각 조건에 따른 최적의 석션보드드레인 공법 영향인자를 산정하고자 하였다. 각 배수재(포켓식 성곽형, 코일형, 하모니카 형, 원형 및 열융착식 성곽형배수재) 종류에 따른 개량 효과를 파악하기 위한 실험 결과, Core 형상(원형, 판형)과 필터의 Core 부착 여부(포켓식, 열융착식)에 의해 열융착식 성곽형 배수재와 포켓식 원형배수재의 배수효율이 다른 배수재의 경우 보다 좋게 나타났다. 단계석션압 조건 실험의 경우 최종 단계석션압인 $-0.8\;kg/cm^2$으로의 기간이 짧을수록 개량도가 크게 나타났다. 또한 각 석션압 단계 별 압밀도-적용기간 곡선 상의 변곡점을 이용하여 압밀효과를 극대화 시킬 수 있는 적용기간을 산정할 수 있었다.

• Genomics & Informatics
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• 제12권4호
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• pp.283-288
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• 2014

Among all serious diseases globally, diabetes (type 1 and type 2) still poses a major challenge to the world population. Several target proteins have been identified, and the etiology causing diabetes has been reasonably well studied. But, there is still a gap in deciding on the choice of a drug, especially when the target is mutated. Mutations in the KCNJ11 gene, encoding the kir6.2 channel, are reported to be associated with congenital hyperinsulinism, having a major impact in causing type 1 diabetes, and due to the lack of its 3D structure, an attempt has been made to predict the structure of kir6.2, applying fold recognition methods. The current work is intended to investigate the affinity of four phytochemicals namely, curcumin (Curcuma longa), genistein (Genista tinctoria), piperine (Piper nigrum), and pterostilbene (Vitis vinifera) in a normal as well as in a mutant kir6.2 model by adopting a molecular docking methodology. The phytochemicals were docked in both wild and mutated kir6.2 models in two rounds: blind docking followed by ATP-binding pocket-specific docking. From the binding pockets, the common interacting amino acid residues participating strongly within the binding pocket were identified and compared. From the study, we conclude that these phytochemicals have strong affinity in both the normal and mutant kir6.2 model. This work would be helpful for further study of the phytochemicals above for the treatment of type 1 diabetes by targeting the kir6.2 channel.

• 한국사회복지학
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• 제56권3호
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• pp.113-133
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• 2004

본인부담과 관련한 이전의 연구들을 살펴보았을 때 외래와 입원 또는 상병별로 환자개인의 본인부담이 진료비에서 차지하는 비율을 파악하여 우리나라 건강보험이 안고 있는 보장기능의 취약성을 거론하거나 이와는 반대로 의료수요의 가격탄력성을 측정, 소비자의 도덕적 해이의 가능성을 지적하는데 초점을 맞추고 있음을 알 수 있다. 그러나 현재 환자본인이 부담하여야 하는 진료비규모를 파악하여 평균 본인부담액의 실제규모와 본인부담률을 밝히는 동시에 만성질환 보유여부, 의료보장의 종류, 또는 의료서비스 기관에 따른 본인부담의 비형평성 문제에 대하여 직접적으로 논의하는 작업은 극히 미미한 실정이다. 높은 본인부담의 결과로 경제적으로 취약하거나 만성질환에 시달리는 계층이 가장 큰 피해를 입게 된다는 점에서 이에 대한 심도 있는 임상적 및 정책적 논의는 절실하다. 이러한 맥락에서 본 연구는 의료서비스에 대한 계층간 본인부담의 차이가 형평성에 미치는 영향을 분석하고 이에 관련된 정책적 함의를 도출하는데 그 목적이 있다. 본 연구의 결과에서 소득 5분위 대비 최하위 계층의 경우 월등히 높은 만성질환 유병률을 보이고 있음에도 불구하고 최상위층의 6배가 넘는 과중한 본인부담을 안고 있음이 밝혀졌다. 또한 최종적인 회귀분석모형 분석결과는 의료이용 빈도 이외에 환자본인의 인구학적 특성, 가구소득, 만성질환 수, 보험의 종류, 상용치료기관의 종류가 본인부담의 규모를 결정짓는데 있어 영향을 미치는 결정적 요인들로 드러났다.

• 한국윤활학회:학술대회논문집
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• 한국윤활학회 2001년도 제34회 추계학술대회 개최
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• pp.186-193
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• 2001

In the high pressure state, the leakage flow rate of hydraulics is one of serious problems and the great reason to decrease the volume efficiency. In this paper, I tried to clarify tribology characteristics for the slipper hydrostatic bearing in swash plate type axial piston pumps and motors by means of experiment . I measured the leakage flow rate between swash plate and piston shoe with change the supply pressure and oil temperature at a swash plate angle of 0。 . And I also investigated the slipper pocket pressure and calculated oil film thickness for theoretical method. So. 1 have analyzed the tribology characteristics of hydrostatic bearing for leakage flow rate and oil film thickness with oil temperature and supply pressure.

• 한국산업융합학회 논문집
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• 제22권5호
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• pp.511-517
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• 2019

Two type pistons which had different configuration were made to find out the effects on combustion and flame propagation. Flame propagation speed was obtained by use of the cylinder head gasket ionization probe. Ionization Probe voltage output and flame propagation speed were increased according to the air fuel mixture ratio increase. Exhaust direction flame propagation speed was fastest in combustion chamber and next was front direction, rear direction and intake direction cause of tumbling motion in cylinder. In case of remove the valve pocket in piston, average flame propagation speed changed slowly and spark timing was advanced. Also emission was decreased.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 추계학술대회 논문집
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• pp.451-457
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• 2008

The aim of the sturdy is for the development of Bridge plate installing on floor for SETPA Sliver line V. SEPTA train have pocket sliding door which is similar with domestic trains. typically In the USA railway market, Portable type and standing type bridge plate used, easily hiding the bridge plate in stowed position and convenience operation, Bridge plate installed on floor is designed. relative regulation Like CFR APTA, and EN, UIC is reviewed and compared.

• 대한치과의사협회지
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• 제47권2호
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• pp.90-101
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• 2009

The aim of this study was to appraise the influence of conventional periodontal treatment on metabolic control in Korean type 2 diabetic patients. In addition, their periodontal change was compared with non-diabetic patients. Before and after treatment, it was performed to measure periodontal and metabolic indices in thirteen type 2 diabetic patients. Periodontal indices included plaque index, gingival index, bleeding on probing, probing pocket depth, gingival recession, and clinical attachment level. Metabolic indices included glycated hemoglobin(HbA1c), fasting plasma glucose, fasting plasma insulin, total cholesterol, triglyceride, and HDL-cholesterol. Plaque index, gingival index, bleeding on probing, probing pocket depth, and gingival recession showed significant improvements in the statistics. Diabetic patients showed no statistically significant differences in the changes of periodontal indices compared with non-diabetic patients. HbA1c values decreased in five of the thirteen subjects and fasting plasma glucose levels were reduced in four of the seven subjects after periodontal treatment. All five subjects whom HOMA values were calculated in showed the increases of insulin secretions. The results of this study ascertained the possibility of the better glycemic contol after conventional periodontal treatment in Korean type 2 diabetic patients and diabetes were well healed of their periodontal diseases after the treatment.