• 한국반도체및디스플레이장비학회:학술대회논문집
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• 한국반도체및디스플레이장비학회 2007년도 춘계학술대회
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• pp.109-112
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• 2007

In this paper we describe a robust method of improving precision in monitoring high energy ion implantation processes. Ion implant energy accuracy was measured in the device manufacturing process using an unpatterned implanted layer on an intrinsic p-type silicon wafer. To increase Rs sensitivity to energy at the well implant process, a PN junction structure was formed by P-well and deep N-well implants into the p-type Si wafer. It was observed that the depletion layer formed by the PN junction was very sensitive to energy variation of the well implant. Conclusively, it can be recommended to monitor well implant processes using the Rs measurement method described herein, i.e., a PN junction diode structure since it shows excellent Rs sensitivity to variation caused by energy difference at the well implant step.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 1999년도 가을 학술발표논문집 Vol.26 No.2 (3)
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• pp.756-758
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• 1999

본 논문에서는 최적의 성능을 갖는 병렬 프로그램을 개발하는데 필수 도구인 성능가시화기를 이식성, 확장성 그리고 효율성을 고려해 설계 및 구현한 PnP 스타일의 성능 가시화기에 대하여 기술한다. 본 가시화기는 기존 가시화기의 문제점인 수정 및 변용에의 어려움을 해결하기 위하여 독립된 계층구조인 인스트루멘테이션층, 인터페이스층, 가시화층으로 구성함으로써 확장성 및 이식성을 갖도록 하였다. 인스트루멘테이션층은 사건(event)을 포획하기 위해 개발된 라이브러리인 ECL(Event Capture Library)로 구성되며, 인터페이스층은 인스트루멘테이션층과 가시화층간에 확장성 있는 문제중심 인터페이스를 제공하기 위해 개발된 사건 기술 언어 및 Java 문제중심 엑세스 라이브러리로 구성되었다. 그리고 PnP 스타일의 성능 가시화기를 설계함으로써 뷰와 필터의 추가 및 수정이 용이하도록 가시화층을 구현하였다. 이렇게 구현된 성능가시화기는 독립된 도구로 사용될 수 있을 뿐 아니라 병렬 프로그래밍, 디버깅, 그리고 성능 분석이 통합된 프로그램 개발환경 구축의 핵심도구로서 활용될 수 있을 것이다.

• ETRI Journal
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• 제38권2호
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• pp.244-251
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• 2016

In this paper, we investigate the electrical characteristics of two trench-gate-type super-barrier rectifiers (TSBRs) under different p-body implantation conditions (low and high). Also, design considerations for the TSBRs are discussed in this paper. The TSBRs' electrical properties depend strongly on their respective p-body implantation conditions. In the case of the TSBR with a low p-body implantation condition, it exhibits MOSFET-like properties, such as a low forward voltage ($V_F$) drop, high reverse leakage current, and a low peak reverse recovery current owing to a majority carrier operation. However, in the case of the TSBR with a high p-body implantation condition, it exhibits pn junction diode.like properties, such as a high $V_F$, low reverse leakage current, and high peak reverse recovery current owing to a minority carrier operation. As a result, the TSBR with a low p-body implantation condition is capable of operating as a MOSFET, and the TSBR with a high p-body implantation condition is capable of operating as either a pn junction diode or a MOSFET, but not both at the same time.

• Bulletin of the Korean Chemical Society
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• 제17권10호
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• pp.919-924
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• 1996

Crystal structure of two inclusion compounds Cd(pn)Ni(CN)4·0.25G (G=toluene and p-xylene, pn=1,2-diaminopropane) have been determined from single-crystal X-ray diffraction data; toluene clathrate: monoclinic P21/n, a=13.838(6), b=26.893(5), c= 7.543(5) Å, γ=90.92(3)°, Z=4, R=0.0616; p-xylene clathrate: monoclinic P21/n, a=13.895(2), b=26.900(3), c=7.613(1) Å, γ=91.06(1)°, Z=4, R=0.0486. The host structures determined for toluene- and pxylene-guest clathrates are substantially identical to the U-type structures observed for the straight chain aliphatic-guest clathrates. However, the alternating arrangement of occupied channels with the guest molecules and vacant channels appears in the host structure. The non-centrosymmetric toluene molecules are distributed about the inversion center to give an image like p-xylene molecule. The guests, toluene and p-xylene, prefer the U-type channel, favoring the interaction between the π-electrons of the aromatic ring and the pn-amino groups to hold the aromatic ring vertical to the cyanometallate meshes.

• Journal of Korean Medical Science
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• 제33권43호
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• pp.277.1-277.10
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• 2018

Background: To examine survival rates and renal function after partial nephrectomy (PN) and radical nephrectomy (RN) in patients with chronic kidney disease (CKD). Methods: We studied 4,332 patients who underwent PN or RN for pathological T1a-T2N0M0 renal cell carcinoma from 1988 to 2014. Patients were divided into two subgroups of CKD stage I-II and stage III. Kidney function, and survival outcomes were compared between groups. Results: We included 1,756 patients with CKD I-II and 276 patients with CKD III in the final pair-matched analysis. Kidney function was significantly better preserved in the PN than in the RN group among all patients. However, the beneficial effect of PN on kidney function gradually disappeared over time in CKD III patients. The 5-year overall survival (OS) rates after PN and RN differed in patients with CKD I-II disease (99.4% vs. 96.5%, respectively, P = 0.015). The 5-year OS rates after surgery were not affected by mode of nephrectomy in CKD III patients (97.8% vs. 93.5%, P = 0.103). The 5-year cancer-specific survival rates did not differ between treatment groups in all CKD stage. Cox hazard analysis showed that the operative method was a significant factor for OS in CKD I-II patients (hazard ratio [HR], 0.320; confidence interval [CI], 0.122-0.840; P = 0.021). However, PN was not beneficial in terms of OS in CKD III patients (HR, 0.395; CI, 0.086-1.172; P = 0.117). Conclusion: PN is associated with a higher OS rate and better kidney function in patients with preoperative CKD stage I and II, but not in those with CKD stage III.

• 대한임상독성학회지
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• 제18권2호
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• pp.123-129
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• 2020

Purpose: Atropine is an antidote used to relieve muscarinic symptoms in patients with organophosphate and carbamate poisoning. Nutritional support via the enteral nutrition (EN) route might be associated with improved clinical outcomes in critically ill patients. This study examined the administration of nutritional support in patients undergoing atropinization, including methods of supply, outcomes, and complications. Methods: A retrospective observational study was conducted in a tertiary care teaching hospital from 2010 to 2018. Forty-five patients, who were administered with atropine and on mechanical ventilation (MV) due to organophosphate or carbamate poisoning, were enrolled. Results: Nutritional support was initiated on the third day of hospitalization. Thirty-three patients (73.3%) were initially supported using parenteral nutrition (PN). During atropinization, 32 patients (71.1%) received nutritional support via EN (9) or PN (23). There was no obvious reason for not starting EN during atropinization (61.1%). Pneumonia was observed in both patient groups on EN and PN (p=0.049). Patients without nutritional support had a shorter MV duration (p=0.034) than patients with nutritional support. The methods of nutritional support during atropinization did not show differences in the number of hospital days (p=0.711), MV duration (p=0.933), duration of ICU stay (p=0.850), or recovery at discharge (p=0.197). Conclusion: Most patients undergoing atropinization were administered PN without obvious reasons to preclude EN. Nutritional support was not correlated with the treatment outcomes or pneumonia. From these results, it might be possible to choose EN in patients undergoing atropinization, but further studies will be necessary.

• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.59-74
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• 2010

Objectives : Atopic dermatitis(AD) is a chronic recurrent skin disease which usually developed in infancy or childhood. AD often repeat improvement and relapse. The cause of AD is so indefinite that many methods of therapies(moisturizer, steroid ointment, antihistamine, immunomodulator, immunosuppressant, herbal medicine, alternative medicine, etc.) are tried. Recently, a lot of studies were made. But there is no report about the effect of Samulsopungeum(SM) and Prednisolone(PN) on AD. So, author aimed to investigate the effects of SM and PN on AD of NC/Nga mice. Methods : Thirty two mice(8 Balb/c mice and 24 NC.Nga mice) were divided into four groups; Balb/c mice was normal group. NC/Nga mice were divide into three group : control, PN, SM group. AD was induced in the control, PN, SM group by spreading DNCB. Then normal saline, PN and SM were orally administered three times in a week for 8 weeks to the control, PN, SM group, respectively. We observed changes of clinical skin severity score, serum IgE, IgG1, IFN-$\gamma$, IL-2, IL-4, IL-5, IL-10, IL-13, and so on. We used one-way ANOVA test statistically(p<0.01). Results : The clinical skin severity scores of PN group and SM group in 8th week were decreased compared to the control group. Serum IgE, IgGl levels of PN group and SM group were significantly decreased compared to the control group. Serum IFN-$\gamma$ in SM group was significantly increased compared to the control group. But, Serum IFN-$\gamma$ in PN group was significantly decreased compared to the control group. Serum IL-10 levels of PN group and SM group were significantly decreased compared to the control group. Serum IL-2, IL-4, IL-5, IL-13 levels of PN group and SM group were significantly decreased compared to the control group. mRNA expression levels of IL-2, IL-4, IL-5, IL-13 in the dorsal skin tissues of PN group and SM group were significantly decreased compared to the control group. According to biopsy reports of the ear and skin tissues showed that the tissue damage of PN group and SM group were highly reduced compared to the control group. Creatinine, BUN, ALT, AST levels of PN group and SM group were normal. Conclusion : According to the above results, it is considered that SM is effective treatment for the AD.

• 한국통신학회논문지
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• 제24권7B호
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• pp.1351-1360
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• 1999

기존의 PN 부호 초기동기 장치는 AWGN 채널에 이상적으로 설계되었으므로 주파수 선택적 레일리 페이딩 채널에서는 이상적인 구조가 아니다. 따라서 본 논문에서는 자동 임계치 제어(Automatic Threshold Control: ATC) 알고리즘을 적용한 디지틀 정합 필터링(DMF)을 기반으로 하여 직접 시퀀스 대역확산(DSSS) 방식에서의 PN 부호 초기동기 장치를 제안하고, 검출확률(PD)과 오류 경보확률(PFA)에 대한 성능을 분석하였다. 초기동기를 위한 탐색 기법은 직렬탐색기법을 고려하였으며, 성능평가를 위한 두 가지 확률은 도플러 주파수, 샘플링 주기, 평균 초기동기 시간 및 PN 칩율 등을 고려하여 주파수 선택적 레일리 페이딩 채널환경에서 유도하고 분석하였다. DMF를 기반으로 한 초기동기 시스템 모델은 시뮬레이션을 결과로부터 ATC 알고리즘을 채택한 모델이 기존의 일정 임계치 시스템보다 성능이 우수하다는 결론을 보였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.641-646
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• 2012

In our recent report on gene expression in gastric cancer we identified the endo-sulfatase Sulf-1 gene to be up-regulated in gastric tumors relative to apparently normal (AN), and paired normal (PN) gastric tissue samples. In the present report we investigate the protein expression levels of Sulf-1 gene in gastric tumors, AN and PN samples using tissue microarray (TMA) and immunohistochemistry. Expression data was collected from two sets of TMA's containing replicate sections of tissue samples. Scoring data from TMA set-1 revealed a significant difference in Sulf-1 immunoreactivity between tumors and "normals" (PN and AN) (p-value = 0.001928). Also, Sulf-1 expression in tumors was also significantly different from either PN (p-value = 0.019) or AN (p-value = 0.006) samples. Similar results were obtained from analysis of scoring data from the second set of arrays. Comparison of mRNA expression and protein expression in gastric tumor tissues revealed that in 6/20 (30%) tumor samples showed up-regulated protein expression concordant with over-expression of mRNA. However, a discord with mRNA being over-expressed relative to down regulated protein expression was observed in majority 14/20 (70%) of tumor samples. Our study indicates down regulation of Sulf-1 protein expression in gastric tumors relative to PN and AN samples which is discordant with mRNA over-expression seen in tumors.

• Journal of Periodontal and Implant Science
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• 제32권2호
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• pp.269-280
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• 2002

The purpose of this study is to develop species-specific DNA probes and polymerase chain reaction (PCR) primers for detection and identification of Prevotella nigrescens (P. nigrescens) 9336. This study procedure includes (1) whole-genomic DNA extraction of P. nigrescens 9336 (2) construction of the genomic DNA library, (3) screening of strain-specific DNA probe by reverse Dot Hybridization method, (4) confirmation of strain-specific DNA probe by Southern blot analysis, (5) determination of nucleotide sequences of strain-specific DNA probe. Thirty-five restriction fragments of P. nigrescens 9336 genomic DNA digested with the Hind III were obtained. Reverse dot hybridization and Southern blot analysis data showed that three of them, Pn10, Pn23, and Pn35, could be P. nigrescens 9336-specific DNA probes. These data indicated that these DNA probes could be useful in detection and identification of the P. nigrescens 9336.