• 생약학회지
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• 제29권4호
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• pp.353-356
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• 1998

Seven flavonoids were isolated from the BuOH extract of the Stem bark of Platycarya strobilacea (Juglandaceae). On the basis of spectroscopic evidences, the structures of these compounds were established as quercetin, 3', 4', 5', 5, 6, 7-hexahydroxyflavone, morin, myricetin, myricitrin, quercitrin and afzelin, respectively.

• 대한화장품학회지
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• 제34권4호
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• pp.275-286
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• 2008

본 연구에서는 굴피나무 수피 추출물의 항산화, 미백 및 주름생성억제에 관한 효과를 측정하였다. 추출물의 free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) 소거활성($FSC_{50}$)은 50% 에탄올 추출물($6.75{\mu}g/mL$) < 당을 제거시킨 aglycone 분획(6.62) < ethyl acetate 분획(4.15) 순으로 증가하였다. Luminol-의존성 화학발광법을 이용한 $Fe^{3+}$-EDTA/$H_2O_2$ 계에서 생성된 활성산소종(reactive oxygen species, ROS)에 대한 총항산화능은 ethyl acetate 분획($OSC_{50}$, $0.56{\mu}g/mL$) < 50% 에탄올 추출물(0.02) < 당을 제거시킨 aglycone 분획(0.01) 순으로 당을 제거시킨 aglycone 분획에서 가장 큰 활성을 나타내었다. 굴피나무 추출물에 대하여 rose-bengal로 증감된 사람 적혈구의 광용혈에 대한 보호효과를 조사하였다. 50% 에탄올 추출물의 경우 농도 의존적($1{\sim}50{\mu}g/mL$)으로 광용혈을 억제하였다. 특히 ethyl acetate 분획은 $10{\mu}g/mL$ 농도에서 ${\tau}_{50}$이 717.27 min으로 매우 큰 세포보호 활성을 나타내었다. 미백 및 주름억제 효과측정으로는 각각 tyrosinase와 elastase의 활성 저해 효과를 측정하였다. Tyrosinase의 활성 저해 효과($IC_{50}$)는 50% 에탄올 추출물 ($243.98{\mu}g/mL$) < ethyl acetate 분획(153.87) < 당을 제거시킨 aglycone 분획(137.53) 순으로 나타났고, elastase의 활성 저해 효과($IC_{50}$)도 50% 에탄올 추출물($31.01{\mu}g/mL$) < ethyl acetate 분획(14.42) < 당을 제거시킨 aglycone 분획(1.48) 순으로, aglycone 분획이 매우 큰 활성 저해 활성을 나타내었다. 또한 굴피나무 추출물 중 ethyl acetate 분획을 함유하는 크림을 제조하고, 이를 피부에 도포한 후, 피부 수분 보유량, 경표피 수분 손실량 그리고 미백효과를 측정하였다. 추출물 함유 크림은 대조군(placebo)보다 수분 보유량을 $2{\sim}8%$ 증가시켰고, 경표피 수분 손실량은 감소시켰다. 또한 추출물 함유 크림은 대조군에 비해 멜라닌 생성을 9.55% 감소시켰다. 이상의 결과들은 굴피나무 추출물이 항산화 활성과 더불어 ROS에 대항하여 세포막을 보호함으로써 생체계, 특히 태양 자외선에 노출된 피부에서 항산화제로서 작용할 수 있음을 가리키며, tyrosinase 및 elastase의 활성 저해 효과와 이를 통한 인체 시험의 결과로부터 미백 기능성 화장품 원료로서 응용 가능성이 있음을 시사한다.

• Applied Biological Chemistry
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• 제46권3호
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• pp.268-270
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• 2003

굴피나무 지상부의 메탄을 추출물을 n-hexane, ethylacetate, n-butanol, $H_2O$으로 순차적으로 용매분획하였다. Ethylacetate 분획으로부터 silica gel chromatography를 반복하여 활성물질을 분리 정제하였다. 화합물은 NMR과 MS의 기기분석 결과 5-hydroxy-2-methoxy-1,4-naphthoquinone로 구조결정 되었다. 이 화합물은 in vivo 실험결과 토마토역병에 대하여 $100\;{\mu}g/ml$에서 76%의 방제효과를 나타내었다.

• 생약학회지
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• 제27권3호
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• pp.238-245
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• 1996

The activity guided fractionation of $CH_2Cl_2$ soluble part of Platycarya strobilacea leaves(Juglandaceae) has led to the isolation of eight active principles, identified as 5-hydroxy-2-methoxy-1,4-naphthoquinone(1), ursolic acid(2), gallic acid(3), 4,8-dihydroxynaphthalene $1-O-{\beta}-_D-glucoside(4)$, eriodictyol(5), quercetin $3-O-(2'-O-galloyl)-{\beta}-_D-glucoside(6)$. quercetin $3-O-(2'-O-galloyl)-{\beta}-_D-galactoside(7)$ and quercetin $3-O-{\alpha}-_L-rhamnoside(8)$ by the means of chemical and spectral evidence, respectively.

• Journal of the Korean Wood Science and Technology
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• 제31권3호
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• pp.30-34
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• 2003

This study was carried out to investigate the constituents of Platycarya strobilacea (Juglandaceae) wood. To isolate compounds, wood was extracted with ethanol (EtOH) and then partitioned with petroleum ether, diethyl ether (Et₂O) and ethyl acetate (EtOAc) successively. After partitioned, diethyl ether fraction was subjected to column chromatography with various solvent system in silica gel and/or Sephadex LH-20. Structures were elucidated by spectroscopic methods including MS, ¹H, ¹³C and 2D-NMR experiments. Three compounds were isolated from the wood and identified as kaempferol 3-O-𝛼-L-rhamnopyranoside (afzelin, I), quercetin 3-O-𝛼-L-rhamnopyranoside (quercitrin, II), myricetin 3-O-𝛼-L-rhamnopyranoside (myricitrin, III).

• Journal of the Korean Wood Science and Technology
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• 제32권5호
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• pp.20-28
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• 2004

경상남도 진해시 제덕동 제덕만 일대 해안에서 발굴된 목재유물 중 일부인 26점의 유물에 대한 수종을 식별한 결과, 소나무류(Pinus spp.) 7점, 상수리나무류(Quercus spp.) 15점, 가시나무류(Quercus spp.) 1 점, 합다리나무(Meliosma oldhami Miq.) 1점, 굴피나무(Platycarya strobilacea S. et Z.) 1점, 서어나무류(Carpinus spp.) 1점으로 판명되었다. 유물의 용도별로 구분하면, 연목(목책)의 경우 소나무류, 상수리나무류, 합다리나무, 서어나무류 등으로 다양한 수종으로 이루어져 있었으며, 선박부재는 모두 상수리나무류이었고, 선체편은 소나무류로 이루어져 있었다. 그리고 용도미상의 나머지 유물은 소나무류, 상수리나무류, 가시나무류 및 굴피나무이었다.

• 동의생리병리학회지
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• 제27권1호
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• pp.57-62
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• 2013

Alzheimer's disease (AD), one of the most common forms of dementia, is characterized pathologically by the presence of intracellular neurofibrillary tangles and deposition of ${\beta}$-amyloid ($A{\beta}$) peptides of 40-42 residues, which are generated by processing of amyloid precursor protein (APP). $A{\beta}$ has been believed to be neurotoxic and now is also considered to have a role on the mechanism of memory dysfunction. Here, we show that MeOH extract from stem bark of Platycarya strobilacea Sieb. et. Zucc. (PSM) affects on the processing of APP from the APPswe over-expressing Neuro2a cell line. We found that PSM may regulate the processing of APP and increase the sAPP${\alpha}$. PSM does not change the protein level of presenilin and nicastrin, however, it reduces the protein expression level of BACE1. In addition, PSM reduces the secretion level of $A{\beta}42$ and $A{\beta}40$ from the cell line without toxicity. We suggest that Platycarya strobilacea may be useful as a herbal medicine to treat Alzheimer's disease.

• Journal of the Korean Wood Science and Technology
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• 제23권3호
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• pp.82-87
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• 1995

Anatomical characteristics of genus Platycarya, Juglans and Pterocarya of Juglandaceae occurring in Korea were described and coded based on the IAWA list. Juglandaceae are ring-porous or semi-ring-porous. Vessels have simple perforation plates and helical thickenings in some genus. Axial parenchyma cells were abundant, most apotracheal but rarely paratracheal and rays with 1-5 seriate. Platycarya is ring-porous wood with 2-3 rows of vessels in the pore zone. Helical thickenings were found only in small vessel of latewood. Axial parenchyma were commonly diffuse-in-aggregates or vasicentric. Rays 3-5 seriate. belonging to Kribs' heterogeneous II or III type with frequent occurrence of rhomboidal crystals. Juglans are semi ring-porous with few vessels in $mm^2$ and pores are commonly solitary. Axial parenchyma were diffuse-in-aggregate or marginal. Rays were mostly homocellular and 3-5 seriates. Pterocarya is similar to Juglans in anatomical features but the reticulate parenchyma consisting of 1 layer on transverse section and biseriate rays.

• The Korean Journal of Ecology
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• 제14권2호
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• pp.181-194
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• 1991

Vascular plants, the structure and interrelationship of the forst vegetation in pyonsan peninsula national park were inverstigated by phytosociological, continuum analysis and ordination methods. The flora was composed of 119 families,411 genera, 609 species, 79 varieties, 10 forma or 698 taxa. Some characteristics of the plants have been represented such as ch-$D_1$-$R_5$ type in biological one, erect form in growth on. It is noticeable that lycoris aurea, carpinus tschonoskii var. eximia, corylus hallaisanensis and abeliophyllum distichun among the investigated plants delong to endemic and/or rare species. The forest vegetation was classified into seven communities: quercus variabilis, pinus densiflora, quercus serrat, platycarya, carpinus tschonoskii, quercus dentata, zelkova serrata community. and quercus variabilis, pinus densiflora and pinus rigida, were the commonest species among distributed species. In addition interrelationship between diversity and dominant indrx of quercus variabilis community was little different each other and that of accordance altitude also was not much distinguishable. Platycarya strobilacea, pinus densiflora and quercus variabilas community were distinguished different groups by polar ordination.

• The Korean Journal of Ecology
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• 제27권2호
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• pp.87-92
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• 2004

Soil respiration rate was measured from March to November 2003 using the KOH absorption method in Pinus densiflora, Quercus variabilis, Platycarya strobilacea stands in Jinju, Gyeongnam Province. Throughout the study period, average soil temperature and moisture content were 16.2$^{\circ}C$, 25.1% for P. densiflora stand, 17.1$^{\circ}C$, 24.3% for Q. variabilis stand, and 17.6$^{\circ}C$, 25.1% for P. strobilacea stand, respectively. The seasonal fluctuations of soil respiration rate increasing in summer and decreasing in winter, which there were strong positive correlations of soil respiration and soil temperature in all study stands. However, there were no significant correlations between soil moisture and soil respiration. Soil respiration rates throughout the study period ranged from 0.12 to 0.77 for P. densiflora stand, 0.23 to 1.37 for Q. valiabilis stand, and 0.30 to 1.47 g $CO_2\cdotm^{-2}\cdothr^{ -1}$ for P. strobilacea stand, respectively. Mean soil respiration rates in P. densiflora, Q. variabilis, P. strobilacea stands were 0.43, 0.80, and 0.90 g $CO_2\cdotm^{-2}\cdothr^{ -1}$, respectively. The Q$_{10}$ values were 2.38 for P. densiflora stand, 2.11 for Q. variabilis stand, and 2.07 for P. strobilacea stand. Annual total soil respiration was 24 for P. densiflora stand, 49.3 for Q. variabilis stand, and 55.3 t $CO_2\cdotha^{-1}\cdotyr^{ -1}$ for P. strobilacea stand, respectively.y.