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Isolation of an Antifungal Compound from Aerial Parts of Platycarya strobilacea  

Chae, Sang-Gi (Department of Plant Resources, Sangju National University)
Kim, Jin-Ho (Department of Plant Resources, Sangju National University)
Kang, Sang-Jae (Department of Horticulture, Sangju National University)
Baek, Nam-In (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyunghee University)
Han, Jae-Taek (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyunghee University)
Choi, Yong-Hwa (Department of Plant Resources, Sangju National University)
Publication Information
Applied Biological Chemistry / v.46, no.3, 2003 , pp. 268-270 More about this Journal
Abstract
Methanol extract obtained from aerial parts of Platycarya strobilacea was successively fractionated with n-hexane, ethylacetate, n-butanol, and water. From ethylacetate fraction, an active compound was isolated through repeated silica gel column chromatography and was identified as 5-hydroxy-2-methoxy-1,4-naphthoquinone by MS and NMR analyses. The compound showed in vivo 76% antifungal activity at $100\;{\mu}g/ml$ against tomato late blight disease.
Keywords
Platycarya strohilacea; tomato late blight; Phytophthora infestans; antifungal activity; 5-hydroxy-2-methoxy-1,4-naphthoquinone;
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