• 대한한방내과학회지
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• 제11권2호
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• pp.112-119
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• 1990

To evaluate effects of Sam so on Pye Tang(SSOPT) Water Extract plasma cortisol concentration and plasma $CO_2$ in the Rabbit. The results obtained were as follows. 1. Intravenous administration of SSOPT water extract at the dose of 0.5ml/kg remarkably increased plasma cortisol concentration on 1 hour. 2. Intravenous adminitration of SSOPT Water extract at the does of 1.0ml/kg significantly decreased plasma $CO_2$ on 1 hour. 3. Intravenous adminitration of SSOPT Water extract at the does of 0.5ml/kg remarkable decreased plasma $Na^+$ from 1 to 4 hour and 1.0ml/kg significantly decreased plasma $Na^+$ on 1 hour. 4. Intravenous administration of SSOPT Water extract at the does of 1.0ml/kg remarkably increased plasma $k^+$ from 1 to 3 hour. 5. Intravenous administration of SSOPT water extract at the does of 0.5ml/kg significantly decreased plasma $CI^-$ on 3, 4 hours. and 1.0ml/kg remarkably increased plasma $CI^-$ on 4 hour. These results suggest that therapeutic action of SSOPT water extract for athma may be reated with the increment of plasma cortisol concentration and the decrease plsma $CO_2.$.

• Asian-Australasian Journal of Animal Sciences
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• 제20권11호
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• pp.1761-1769
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• 2007

This experiment was conducted to determine the extent to which susceptibility to cortisol-induced follicle shutdown is influenced by fleece phentotype. Twenty Finewool (10 sheep low fibre diameter, low coefficient of fibre diameter-LL and 10 low fibre diameter, high coefficient of variation of fibre diameter-LH) and twenty Strongwool (10 low fibre diameter, low coefficient of variation of fibre diameter-HL and 10 high fibre diameter and high coefficient of variation of fibre diameter-HH) sheep of 9 months of age were individually penned in an animal house and were injected intramuscularly with an aqueous suspension of hydrocortisone acetate at a rate of 1.42 mg/kg body weight for a period of two weeks. Fibre diameter was measured from clipped tattooed patch wool samples. Follicle activity was measured by histological changes in skin biopsies taken weekly. Blood samples were collected at two-week intervals and plasma cortisol measured. Increased plasma cortisol concentration significantly (p<0.05) reduced clean wool production and mean fibre diameter dropped to its lowest level four weeks after commencement and two weeks after the cessation of cortisol injection. Elevation of plasma cortisol concentration significantly (p<0.0001) increased the percentage of inactive follicles two weeks after injection started. High fibre diameter groups (Strongwool sheep; i.e. HL+HH) had significantly (p<0.0001) higher percentage of follicle shutdown than low fibre diameter groups (Finewool sheep; i.e. LL+LH). Average percentage of shutdown follicles for Finewool (LL+LH) and Strongwool (HL+HH) Merino sheep was $9.8{\pm}0.9$ and $13.5{\pm}0.9$ respectively. Shutdown of primary follicles was more pronounced in Finewool than Strongwool sheep. There was no significant effect of coefficient of variation of fibre diameter on propensity to follicle shutdown induced by exogenous cortisol. It is concluded that elevation in plasma cortisol concentration is inhibitory to the normal activity of follicles in Strongwool sheep but that variation in fibre diameter has little or no effect.

• 여성건강간호학회지
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• 제7권1호
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• pp.67-79
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• 2001

This study was designed to verify the effect of Doula-type-delivery nursing care on plasma $\beta$-endorphin, serum cortisol, related to delivery stress during labor, and postpartum anxiety of primipara by a quasi experiment(nonequivalent control group pretest-posttest design), from December, 1999 to August, 2000. The subjects of this experiment consisted of sixty eight primipara, with single gestation, full term, uncomplicated pregnancies, thirty three for the experimental group and thirty five for the control group. Their mean age was 26.1 years for the experimental group and 25.5 years for the control group. Their mean gestation period was 39.7 weeks for the experimental group and 40.1 weeks for the control group. As treatment, Doula-type-delivery nursing care was given for the experimental group. Data assessed plasma $\beta$-endorphin, serum cortisol during labor, and anxiety during postpartum. Plasma $\beta$-endorphin, serum cortisol were measured in the latent phase before treatment(pre-test) and the transition phase after treatment(posttest). Also, anxiety was measured in the latent phase before treatment(pre-test) and 24 hours postpartum after treatment(posttest). Data was analyzed by t-test, $x^2$-test, Repeated measures ANOVA with SAS Program. The results of this study were as follows; 1. Plasma $\beta$-endorphin was significantly elevated in the experimental group who were cared for with Doula-type-delivery nursing care during labor(P=.0463). 2. No significant group effects were found, but significant time effects were found for serum cortisol. 3. The postpartum anxiety of the experimental group was significantly lower than the control group(P=.0110). In conclusion, these findings indicate that Doula-type-delivery nursing care during labor could be effective in increasing maternal plasma $\beta$-endorphin and decreasing postpartum anxiety. Doula-type-delivery nursing care during labor could be applied as an effective nursing treatment for primipara.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1972년도 제11차 학술대회
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• pp.71.3-72
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• 1972

• Asian-Australasian Journal of Animal Sciences
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• 제32권5호
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• pp.734-741
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• 2019

Objective: The objective of the study was to determine the relationship between plasma and salivary cortisol concentrations in beef cattle that were subjected to handling prior to sampling. Methods: Twenty-one Nguni cows of three age categories; 5 to 7 yr (n = 7), 8 to 10 yr (n = 6), and 11 to 13 yr (n = 8) were handled for five consecutive weeks. In the pen, a human avoidance test was performed and cattle responses to restraint in the chute and crush were observed. In addition, rectal temperature readings were taken and, faecal samples were collected and analysed for glucocorticoid metabolites. Through the handling and restraint process, excretory and vocalisation behaviour, as a sign of stress were observed and recorded. Thereafter, six cows were randomly selected and subjected to an adrenocorticotropic hormone (ACTH) challenge. Blood and saliva samples were extracted to determine cortisol concentrations. Results: Repeated handling affected (p<0.05) faecal glucocorticoid metabolites, rectal temperatures, avoidance distance, crush scores as well as urination and defaecation behaviour. Acclimation to handling was variable based on each respective parameter. Saliva cortisol concentrations increased and decreased significantly (p<0.001). A peak value of $136.78{\pm}15.869nmol/L$ was observed 30min after administration of ACTH, from a baseline value of $8.75{\pm}15.869nmol/L$. Plasma cortisol concentrations did not differ (p>0.05) across the time of sampling. A low and insignificant correlation (r = 0.0131, p>0.05) between plasma and saliva cortisol was therefore observed. Conclusion: We conclude that if beef cows are subjected to handling prior to sampling, a weak relationship exists between plasma and salivary cortisol levels.

• Asian-Australasian Journal of Animal Sciences
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• 제9권1호
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• pp.57-61
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• 1996

Four castrated Corriedale sheep were used in an experiment to observe the changes in insulin, growth hormone and cortisol in blood plasma following a prolonged infusion of a high rate of somatostatin (SRIF). The animals wee infused with either saline, 25 or $50{\mu}g/kg/h$ of SRIF for 3 hours. Blood samples wee taken every 20 minutes until 1 hour following the end of the SRIF infusion. Both SRIF infusion levels suppressed the release of insulin into plasma to approximately 3.5 mU/l. The SRIF infusions reduced the concentration of growth hormone to barely detectable levels. Following the withdrawal of SRIF there was a massive release of growth hormone. The plasma concentration of growth hormone reached 60 ng/ml within 20 minutes, the length of the growth hormone discharge was in excess of 1 hour. The extent of the discharge of growth hormone following the SRIF infusions was greater than that suppressed by the infusion. The SRIF apparently caused an increase in the plasma concentration of cortisol at the end of the infusion and following is withdrawal. This is possibly associated with some change in the metabolic rate associated with the suppression of insulin or glucagons release. The present experiment demonstrates that a high rate of SRIF infusion can not completely inhibit the release of insulin into the plasma.

• 성인간호학회지
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• 제19권2호
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• pp.207-216
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• 2007

Purpose: The purpose of this study was to ascertain the effects of preoperative information on postoperative state anxiety, plasma cortisol, and pain for patients under total knee arthroplasty, and to provide generic data with nursing intervention for total knee arthroplasty. Methods: Data were collected from 34 patients who had total knee arthroplasty from January 3, 2003 to January 15, 2004. An experiment group of 17 patients was provided with pre-operative information prepared by the researchers; a control group of another 17 patients was provided with general information. Data were analyzed through Chi-squared test, t-test, paired t-test and ANCOVA using SPSS WIN 11.0. Results: There was no significant differences between the experiment group and the control group in post operative state anxiety(p=.612). However, there was statistically a significant difference between the above two groups in post operative plasma cortisol(p=.012). There was a statistically significant difference between the above two groups in post operative pain(p=.041). Conclusion: According to the results of the study, the authors concluded that the preoperative information for patients under total knee arthroplasty had the effect on the decrease of postoperative plasma cortisol and pain.

• 한국축산시설환경학회지
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• 제1권1호
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• pp.39-45
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• 1995

Temperatures of blood and skin, respiratory rate and plasma cortisol concentration in sheep at a warm (average ambient temperature of $15.3^{\circ}C$) and a hot (average ambient temperature of $27.0^{\circ}C$ environment were measured to investigate the effect of hot environment on the physiological responses in ruminant. Temperatures of core, mean skin and mean body in sheep were tended to increase at day time and to decrease at night time at both warm and hot environment, while 24-hr average for those temperatures were significantly higher at hot environment than at warm environment (P<0.05). The calculated body heat content was higher in sheep at hot environment than at warm environment (P<0.05). Respiratory rate and plasma cortisol concentration had no significant differences between warm and hot environment, suggesting that sheep were not stress by the hot environment in this experiment. It is, therefore, suggested that sheep were well adopted to hot environment by increasing body heat content against heat stress.

• 대한한방내과학회지
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• 제11권1호
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• pp.127-140
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• 1990

To evaluate effects of Pai Mo San (PMS) water extract on the plasma cortisol concentration and arterial blood $PCO_2,\;PO_2$ in the rabbit. The results obtained were as follows: 1. Intravenous administration of PMS water extract at the dose of 0.2 ml/kg remarkably increased plasma cortisol concentration from 1 to 2 hours. 2. Intravenous administration of PMS water extract at the dose of 0.4 ml/kg plasma cortisol concentration showed more significant increase than the control group after 1,2,4 hours. 3. No change observed in the arterial blood $PO_2$ after intravenous administration of PMS water extract at the dose of 0.2 ml/kg used. 4. No change observed in the arterial blood $PO_2$ after intravenous administration of PMS water extract at the dose of 0.4 ml/kg used. 5. Intravenous administration of PMS water extract at the dose of 0.2 ml/kg arterial blood $PCO_2$ showed more significant decreased than the control group after 1,3 hours. 6. Intravenous administration of PMS water extract at the dose of 0.4 ml/kg significantly decreased arterial blood $PCO_2$. These results suggest that the therapeutic action of Pai Mo San water extract for Yeol Su (熱嗽), Wha Su (火熱), Gu Su (久熱) and anti-asthma maybe related with the increase of plasma cortisol, decrease of $PCO_2$.

• 대한한방내과학회지
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• 제11권2호
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• pp.94-103
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• 1990

To evaluate effects of Ga Gam Sam Kee Tang(GGSKT) water extract on the plasma cortisol concentration and arterial blood $PCO_2,\;PO_2$ in the rabbit. The results obtained were as follows : 1. Intravenous administration of GGSKT water at the dose of $0.2m{\ell}/kg$ remarkably increased plasma cortisol concentration from 1 to 2 hours. 2. Oral administration of GGSKT water extract at the dose of $10m{\ell}/kg$ significantly decreased plasma cortisol concentration on 3 hours. 3. Intravenous administration of GGSKT water extract at the dose of $0.4m{\ell}/kg$ remarkably decreased arterial blood $PO_2$ on 2 hours. 4. Oral administration of GGSKT water extract at the dose of $1.0m{\ell}/kg$ significantly decreased arterial blood $PO_ 2$ on 2 hours and remarkably increased on 4 hours. 5. Intravenous administration of GGSKT water extract at the dose of $0.2m{\ell}/kg$ remarkably increased arterial blood $PCO_2$ on 4 hours. 6. Oral administration of GGSKT water extract at the dose of $2.0m{\ell}/kg$ significantly decreased arterial blood $PCO_2$ from 1 to 2 hours. These results suggest that therapeutic action of GGSKT water extract for athma may be related with the increment of plasma cortisol concentration and the decrease of arterial blood $PCO_2$.