• 한국콘텐츠학회논문지
• /
• 제17권9호
• /
• pp.324-330
• /
• 2017

본 연구는 수분이 많은 청정식품의 경도라는 규격화된 기준을 두어, 경도에 따른 청정 작용의 효과 차이를 알아보고, 그 효과로 구취가 제거되는 정도를 알아보고자 하였다. 본 연구에 참여한 대상자는 평균 20.8세의 여성 19(95.0%)명, 남성 1(5.0%)명이었다. 자료 분석은 PASW SPSS statistics 24.0(IBM Co,Armonk,NY,USA)를 사용하였으며, 제1종 오류는 0.05로 하였다. 모든 청정식품에서의 섭취 전과 섭취 후의 치면 세균막의 제거정도는 오이는 PHP Index, 토마토는 PHP Index와 plaque rate, 배추는 plaque rate가 통계학적으로 유의한 차이를 보였고, 경도에 따른 청정식품 종류의 치면세균막 제거 효과에는 유의한 차이는 없었다. 모든 청정식품에서의 구취제거 효과에는 구취성분 중 $H_2S$만이 통계학적으로 유의한 차이가 있으나, 변화량의 평균이 배추, 토마토, 오이순으로 청정식품의 경도에 따라서는 구취제거 효과가 나타나지 않았다. 향후 청정식품 종류의 다양화와 많은 피험자의 수, 구취측정 시간을 통제하는 등의 여러 요소를 고려하여 후속 연구를 진행할 필요가 있으며, 실생활에서도 이를 활용한 식이조절법이 활성화 될 수 있도록 식품에 관한 임상연구가 필요할 것이다.

• 치위생과학회지
• /
• 제20권4호
• /
• pp.245-251
• /
• 2020

Background: This study tries to compare and analyze the removal effect of dental plaque of general dentifrice and pregnant women's dentifrice and quantify the results to provide basic data so that consumers can make reasonable choices when purchasing dentifrice, and also increase interest in the dental plaque. Methods: After forming a dental plaque (carbohydrate porridge) on the labial surface of the bovine teeth, a disclosing agent was applied. Then the same experimenter brushed the surface of the bovine teeth using an electric toothbrush and took photographs using a DSLR camera. Thereafter, the residual amount of dental plaque was analyzed using the ImageJ program, and SPSS 26.0 was used for statistical processing. Results: The average residual amount of dental plaque using the general dentifrice was 11.71% for Perio, 9.45% for Cliden, and 8.47% for 2080, and the average residual amount for the three types was approximately 9.88%. The average residual amount of dental plaque of pregnant women's dentifrice was 13.95% for Jeninmothers, 12.53% for Tntnmoms, and 12.63% for Mommiracle, and the average residual amount of the three types was approximately 13.04%. On comparing the average residual amount of dental plaque between general and pregnant women's dentifrices, it was observed to be 3.16% higher for the latter. However, the results were not statistically significant. Conclusion: According to the research results, there was no significant difference in removal effects of general dentifrice and pregnant women's dentifrice. In addition, when a pregnant woman uses the right toothbrushing method with pregnant women's dentifrice, it can prevent or inhibit the progression of the gestational periodontal disease. Therefore, we recommend pregnant women to use pregnant women's dentifrices.

• 한국치위생학회지
• /
• 제8권2호
• /
• pp.67-76
• /
• 2008

The purpose of this study was to determine the effect of dentifrice containing 0.1% extracts of garlic on dental plaque and gingivitis in a double blind and crossover clinical studies in 33 healthy adults aged from 20 to 22 years who provided a consent for their participation. Oral examination was performed through clinical periods and on day of baseline, 6, 13, 19, 25 days plaque index and gingival index were scored by Turesky' modified index and L$\ddot{o}$e & Silness index. After 12, 19, 25 days use of their respective dentifrices, statistically decreases of plaque index, gingival index were shown in both the experimental and the control group, respectively, Experimental group exhibited significantly the lower plaque levels and the higher levels of gingival health by the use of the dentifrices contained extract of garlic from 12 days compare with control group(p<0.05). The degree of decrease was more significant on gingivitis level of the experimental group than the control group(p <0.05). This result indicate that the use of dentifrice containing extract of garlic has a positve effect in preventing plaque and gingivitis and treating periodontal diseases.

• 대한치과보철학회지
• /
• 제26권1호
• /
• pp.197-206
• /
• 1988

The purpose of this study was to investigate the effect of wearing the removable partial denture on plaque accumulation. Twelve removable partial denture cases were examined. Patients were recalled three consecutive 3 day periods. Plaque index was measured after each 3 day period. (1) not wearing the denture, (2) wearing the denture, (3) wearing the denture after intensive tooth brushing instruction. The results were as follows: 1. Plaque indices of all the remaining teeth were higher following the wearing of removable partial denture than those of teeth not wearing the denture and those of teeth after intensive tooth brushing instruction. 2. Plaque indices showed statistical difference between all the tooth surfaces which were in contact with the denture and those which were not. 3. Plaque indices showed no statistical difference between buccal and lingual surfaces which were in contact with the denture and those which were not. 4. Plaque indices showed statistical difference between proximal surfaces which were in contact with the denture and those which were not.

• 대한소아치과학회지
• /
• 제11권1호
• /
• pp.215-232
• /
• 1984

The purpose of this research was to analyze the relationship between parents' attitudes toward their children's dental health and dental plaque index. Dental plaque index was obtained through oral examination of 118 children(female 40, male 78) with primary dentition The maintenance status of children's dental health though parents' aids was evaluated by means of questionaire to which 79 persons among the 118 children's parents answered. The results were as follows : 1. In children with primary dentition, toothbrushing together with toothbrushing instruction and continuous reinforcement had decreased plaque accumulation progressively. 2. Dental plaque index before toothbrushing showed that dental plaque was accumulated more in the buccal surfaces of teeth in the maxilla and in the lingual surfaces of teeth in the mandible. It was higher in the posterior teeth than in the anterior teeth and in the maxillary teeth than in the mandibular teeth. 3. Dental plaque index of childern was inversely proportional to the level of education of their parents. 4. Those parents who have much knowledge of oral hygiene were more positive toward their children's oral hygiene.

• 한국치위생학회지
• /
• 제5권1호
• /
• pp.123-130
• /
• 2005

This study was executed to evaluate the effects of natural herbal medicine extract on the antimicrobial activity and the artificial plaque formation. Schisandra chinensis, Sophora flavescens, Dryopteris crassirhizoma and Aristolochia contorta were extracted by 80% MeOH respectively and each concentration(5mg, 10mg, 20mg) of herbal medicine extract was tested to show the antimicrobial activity against S. mutans. To show the inhibition effect of herbal medicine extract on the artificial dental plaque formation each extract of 0.4% concentration was added into M 17 broth and inoculated with $5.0{\times}10^6$ of S. mutans. After 24 hour incubation each weight of artificial dental plaque was measured and compared with each other. Results obtained are as follows: 1. Dryopteris crassirhizoma showed very intense antimicrobial effect but Schisandra chinensis, Sophora flavescens and Aristolochia contorta showed a little difference against control. 2. Regarding artificial plaque formation inhibiting activity by each herbal extract at 0.4% concentration, Dryopteris crassirhizoma showed the perfect inhibition effect. Schisandra chinensis and Aristolochia contorta followed in order but Sophora flavescens showed the worst value. In conclusion, Dryopteris crassirhizoma showed strong antimicrobial effect against S. mutans and significant inhibiting effect on the artificial dental plaque formation.

• Archives of Pharmacal Research
• /
• 제13권2호
• /
• pp.211-213
• /
• 1990

To test flavonoids for antibacterial activity against oral micraorganisms, flavonoids, quercetrin and naringenin, were incorporated into two pharmaceutical preparations in the form of tooth paste. Samplees of dental plaque, the msot accused dental deposit which initiates the gingival and periodental diseases, were collected from the teeth surface of ten dental students at one week interval before and after using placebo, followed by two formulae of tooth paste containing 0.1% of quercetrin and naringenin (formulas I and II, respectively). The amount of dental plaque was assessed by the quigley and Hens index. Then plaque samples were subjected to bacteriological examination of Gram stain and plate counts of microorganisms. The amount of dental plaque was assessed by the Quigley and Hens index. Then plaque samples were subjected to bacteriological examination of Gram stain and plate counts of microorganisms. The results revealed that most of Gram negative cocci and bacilli were highly affected by the two formulae : the number of actinomycetes were decreased after using formula I and disappeared completely by the sue of formula II, while the number of Gram positive streptococci was highly decreased after the treatment with the two formulae. These results indicate a possible use of flavonoids to inhibit dental plaque formation.

• Korean Journal of Radiology
• /
• 제25권6호
• /
• pp.518-539
• /
• 2024

Coronary computed tomography angiography (CCTA) has emerged as a pivotal tool for diagnosing and risk-stratifying patients with suspected coronary artery disease (CAD). Recent advancements in image analysis and artificial intelligence (AI) techniques have enabled the comprehensive quantitative analysis of coronary atherosclerosis. Fully quantitative assessments of coronary stenosis and lumen attenuation have improved the accuracy of assessing stenosis severity and predicting hemodynamically significant lesions. In addition to stenosis evaluation, quantitative plaque analysis plays a crucial role in predicting and monitoring CAD progression. Studies have demonstrated that the quantitative assessment of plaque subtypes based on CT attenuation provides a nuanced understanding of plaque characteristics and their association with cardiovascular events. Quantitative analysis of serial CCTA scans offers a unique perspective on the impact of medical therapies on plaque modification. However, challenges such as time-intensive analyses and variability in software platforms still need to be addressed for broader clinical implementation. The paradigm of CCTA has shifted towards comprehensive quantitative plaque analysis facilitated by technological advancements. As these methods continue to evolve, their integration into routine clinical practice has the potential to enhance risk assessment and guide individualized patient management. This article reviews the evolving landscape of quantitative plaque analysis in CCTA and explores its applications and limitations.

• 대한소아치과학회지
• /
• 제45권1호
• /
• pp.32-40
• /
• 2018

본 연구는 치태의 성숙도에 따라 치태를 서로 다른 색상으로 염색하는 GC Tri Plaque ID $Gel^{TM}$(GC corporation, Tokyo, Japan)을 이용하여 치아 우식 위험도를 평가하고자 하였다. 치아 우식의 발생 및 진행과 연관된 균인 Streptococcus mutans, Streptococcus sobrinus, Lactobacillus spp.의 수를 Quantitative real-time polymerase chain reaction (qRT-PCR)로 측정하여 치아 우식 위험도를 보았다. 본 실험은 강릉원주대학교 치과병원 임상시험 심사위원회의 심의를 받고 진행하였다. 강릉원주대학교 치과병원 소아치과에 내원한 전신질환이 없는 건강한 9 - 12세의 초등학생 15명의 치면을 착색제로 염색하였다. 치태의 성숙도에 따라 서로 다른 세가지 색상으로 염색되었으며 색상별로 3개의 실험군인 I군(pink/red), II군(blue/purple), III군(light blue)으로 나누었다. 3개의 실험군에서 각각 DNA를 추출한 후, qRT-PCR을 이용하여 S. mutans, S. sobrinus, Lactobacillus spp.의 수를 측정하였다. 3개의 실험군 사이에 S. mutans, S. sobrinus와 Lactobacillus spp. 균 수의 유의한 차이가 관찰되었으며 3종류의 균 모두 III군에서 가장 많이 관찰되었다(p < 0.05). GC Tri Plaque ID $Gel^{TM}$는 기존 착색제와는 달리 치태의 성숙도에 따라 서로 다른 세가지 색상으로 염색되며, 치태 염색 색상의 차이는 치아 우식 관련 균 수의 차이를 보여주었다. GC Tri Plaque ID $Gel^{TM}$이 치아 우식 위험도를 평가하는 하나의 지표로서 사용될 수 있는 가능성을 확인하였다.

• 미생물학회지
• /
• 제38권3호
• /
• pp.221-229
• /
• 2002

일본뇌염바이러스(Japanese encephalitis virus, JEV) Nakayama strain을 초기 multiplicity of infection 5.0으로 Vero세포에 감염하여 1년 이상 안정적으로 바이러스를 방출하는 지속감염(persistently-infected)세포주를 확립하였다. 지속감염 세포에서 지속적으로 방출되는 총 11 개의 Plaque 형태 변이바이러스(morphology mutants)클론을 확보하였다. 분리된 변이바이러스의 복제효율을 분석한 결과 생물학적 표현형과 복제효율은 유의하게 상관하였다. 변이바이러스 RNA 게놈 양 말단의 non-coding region 및 envelop 단백질의 ORF에서는 유의한 염기서열 변화가 관찰되지 않아 JEV 약독화에 새로운 인자가 추가로 관여할 가능성을 제시하였다. 변이바이러스에 감염된 신선한 Vero세포는 wild-type JEV의 일반적 감염성상과 다르게 대다수의 세포가 유의할 만한 세포병변현상을 나타내지 않았다. 감염된 Vero세포에서 wild-type JEV 및 large plaque을 형성하는 변이바이러스의 경우 mRNA와 함께 Bcl-2의 발현은 모두 유의하게 감소하였으며 p53은 뚜렷하게 증가하였다. 반면 small plaque을 형성하는 변이바이러스의 감염세포에서는 Bcl-2와 p53 모두 유의한 변화를 볼 수 없었다. 이상의 결과들과 함께, 감염된 Vero세포의 internucleosomal DNA fragmentation과DNA profile의 유형분석에 따르면 궁극적 인 세포병변효과의 변화는 변이바이러스의 복제효율과 더불어 p53에 비의존적인 apoptosis 수위의 전반적인 감소에 기인하는 것으로 판단된다.