• 제목/요약/키워드: Plant Resources

검색결과 8,229건 처리시간 0.038초

한반도 미기록 외래식물: 서양쐐기풀 (New Record for Alien Plant, Urtica dioica L. (Urticaceae) in Korea)

  • 심선희;김진석;진동필;이웅;현창우;김중현
    • 한국자원식물학회지
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    • 제35권1호
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    • pp.100-108
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    • 2022
  • 한반도 미기록 외래식물인 서양쐐기풀(쐐기풀과)를 한강 수계에서 발견하였다. 서양쐐기풀은 유럽, 온대 아시아, 서북아프리카 원산으로 알려져 있으며, 세계의 여러 지역에 도입되어 있는데 특히, 동아시아(일본), 오세아니아, 남아메리카에서 외래종으로 보고되었다. 본 분류군은 단성화이며, 자웅이주를 가지는 특징에 의해 근연분류군과 구분된다. Neighbor-Joining 계통수에서 국내 난지한강공원과 양재천에서 채집된 서양쐐기풀은 U. dioica s.s.군으로 유집되었다. 주요 형질에 대한 기재문과 화상자료 및 검색표를 제시하였다.

Immunostimulatory Activity of Hibiscus syriacus L. Leaves in Mouse Macrophages, RAW264.7 cells, and Immunosuppressed Mice

  • Na Gyeong Geum;Ju Hyeong Yu;So Jung Park;Min Yeong Choi;Jae Won Lee;Gwang Hun Park;Hae-Yun Kwon;Jin Boo Jeong
    • 한국자원식물학회지
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    • 제35권6호
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    • pp.697-703
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    • 2022
  • Under the COVID-19 pandemic, interest in immune enhancement is increasing. Although the immune-enhancing activity of plants of the genus Hibiscus has been reported, there is no study on the immune-enhancing activity of H. syriacus. Thus, in this study, we investigated the immune-enhancing activity of Hibiscus syriacus leaves (HSL) in mouse macrophages, RAW264.7 cells, and immunosuppressed mice. HSL increased the production of immunostimulatory factors such as nitric oxide (NO), inducible nitric oxide synthase (iNOS), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) and activated the phagocytosis in RAW264.7 cells. The HSL-mediated production of immunostimulatory factors was dependent on toll-like receptor 4 (TLR4), p38, and c-Jun N-terminal kinase (JNK) in RAW264.7 cells. In the immunosuppressed mouse model, HSL increased the spleen index, the levels of the cytokines, and the numbers of lymphocytes, neutrophils, and monocytes. Taken together, HSL may be considered to have immune-enhancing activity and be expected to be used as a potential immune-enhancing agent.

Anticancer Activity of Sageretia theezans in Human Colorectal Cancer Cells

  • Kim, Ha Na;Park, Su Bin;Kim, Jeong Dong;Jeong, Hyung Jin;Jeong, Jin Boo
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2018년도 추계학술대회
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    • pp.108-108
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    • 2018
  • In this study, we evaluated the anti-cancer effect of extracts of leaves (ST-L) and branches (ST-B) from Sageretia theezans in human colorectal cancer cells. ST-L and ST-B significantly inhibited the proliferation of human colorectal cancer cells, SW480. ST-L and ST-B decreased cyclin D1 protein level through the induction of cyclin D1 proteasomal degradation via $GSK3{\beta}$-dependent threonine-286 phosphorylation of cyclin D1. In addition, ST-L and ST-B increased HO-1 protein through p38, ROS and $GSK3{\beta}$-dependent Nrf2 activation. These findings suggest that ST-L and ST-B may have great potential for the development of anti-cancer drug to treat human colorectal cancer.

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추출조건에 따른 작약의 대식세포 활성화 유도 (Induction of Macrophage Activation of Paeonia lactiflora according to Extraction Conditions)

  • 유주형;박소정;우진희;신나래;정진부
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2022년도 추계학술대회
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    • pp.91-91
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    • 2022
  • 작약은 염증성 질환을 치료하기 위해 사용되어 온 전통 약용식물이다. 최근 작약은 대식세포에서 면역조절인자의 분비를 증가시키고 포식작용을 증가시킨다고 보고되었다. 그리하여 본 연구에서 추출조건별 작약의 대식세포 활성화 유도를 비교하였다. 온도조건 별 작약추출물은 4℃에서 60℃까지는 면역조절인자의 분비를 증가시켰지만, 80℃에서는 면역조절인자의 분비가 다소 감소하였다. 60℃에서 시간별 추출조건에서는 1시간에 24시간까지 면역조절인자의 분비가 유사하였다. 따라서 본 연구결과를 종합해 볼 때, 작약은 60℃에서 1시간 추출하는 것이 대식세포 활성화를 위한 최적 조건이라고 판단된다.

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The Branch Extracts of Vaccinium oldhamii Stimulate Melanin Synthesis Through Activation of Tyrosinase Activity in B16F10 Melanoma Cells

  • Park, Su Bin;Kim, Ha Na;Kim, Jeong Dong;Park, Gwang Hun;Son, Ho-Jun;Eo, Hyun Ji;Song, Jeong Ho;Jeong, Hyung Jin;Jeong, Jin Boo
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2018년도 추계학술대회
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    • pp.95-95
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    • 2018
  • In this study, we investigated the effect of branch extracts from Vaccinium oldhamii (VOB) on melanin synthesis in B16F10 cells. VOB promoted melanin production in absence or presence of ${\alpha}$-melanocyte-stimulating hormone (${\alpha}-MSH$) in B16F10 cells. However, VOB did not affect the expression of tyrosinase and TRP-1 associated with melanin synthesis at the mRNA and protein level in B16F10. But, VOB decreased TRP-2 protein level and induced tyrosinase activation in B16F10 cells. Inhibition of tyrosinase activity and tyrosinase knockdown attenuated VOB-mediated melanin synthesis. In conclusion, it is thought that VOB may stimulate melanin synthesis through activating tyrosinase activity.

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