• Herbal Formula Science
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• v.15 no.1
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• pp.175-183
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• 2007

This study was conducted to evaluate the inhibitory effects of Yongseollan(YSL) on the production of nitric oxide (NO) and the expression of inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-activated RAW264.7 cells. YSL is tropical plant originating from Mexico. The biological activity of this plant is not yet evaluated systematically. The aim of the present work is to investigate a potential anti-inflammatory activity of YSL. The RAW264.7 cells were cultured in D MEM/F12 medium for 24 hrs. After serum starvation, cells were treated with YSL for 1 hr, followed by stimulating NO production with a LPS. We found that YSL has an inhibitory effect on the production of NO, iNOS expression and $phospho-I{\kappa}B$ expression. YSL also inhibited tumor necrosis factor $(TNF)-{\alpha}$, interleukin (IL)-6, and $IL-1{\beta}$. Moreover, YSL inhibited cyclooxygenase (COX)-2 expression and prostanglandin E2 (PGE2). These findings showed that YSL could have some anti-inflammatory effects which might play a role in therapy in Gram-negative bacterial infections.

• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.51-68
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• 2010

Hanyak, Korean herbal medicine is defined as the herbs understood and explained by traditional Korean medical theories. Considering this definition, there are broad prospective of every species being consilienced and utilized as Korean herbal medicine. Most varied plant species are in tropical regions, and its of these regions posses its own particular traditional medicine. Brazil posses the most varied and abundant plant species and also characteristic traditional medicine, formed by the combination of native indians and immigrants from Africa and Europe. Brazilian traditional medicine are practices by 'garrafeiros', 'raizeiros', or 'curandeiros' and in Caatinga uses herbs in ritual ceremonies. But threatened by modernization, these knowledge may be vanished in a prompt time. Therefore we carried this research in the propose of understanding as well as preserving their traditional medical knowledge. We revised publications about the medical plants and summarized 314 species of 94 families according to repetitive references. The most cited families were COMPOSITAE, LABIATAE, LEGUMINOSAE, RUBIACEAE, SOLANACEAE, UMBELLIFERAE, VERBENACEAE. Also cited major medical efficacies which further medical uses in combinations or modification of current traditional Korean medicine should be studied. This study provides overall prospect of the plants resources of Brazil and their uses. It may serve in the consilience and understanding of varied traditional medicine by traditional Korean Medicine.

• Proceedings of the Plant Resources Society of Korea Conference
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• v.18 no.1
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• pp.153-155
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• 2005

• Plant Resources
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• v.6 no.3
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• pp.175-177
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• 2003

This study was conducted to investigate the effect of Activated charcoal (AC) for stimulating growth and productivity of Curcuma longa Linne as affected by different concentrations of AC. Growth characteristics such as plant height and leaf length were the highest with the optimum amount of activated charcoal ranged from 10 to 30%. Root growth was elongated by the addition of 30% AC with the highest rhizome length and weight.

• Korean Journal of Pharmacognosy
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• v.41 no.4
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• pp.289-296
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• 2010

Aldose reductase (AR), the principal enzyme of the polyol pathway, has been shown to play an important role in the development of the diabetic complications. Evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Sixty four Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, thirteen herbal medicines, Inula helianthus-aquatilis C. Y. Wu ex Ling. (whole plant), Erigeron breviscapus (Vant.) Hand. Mazz. (whole plant), Lonicera hypoglauca Miq. (leaf, stem), Scutellaria orthocalyx Hang. Mazz. (whole plant), Berchemia floribunda Brongn. (leaf, stem), Michelia alba DC. (flower), Oroxylum indicum (seed), Punica granatum L. (peel), Elsholtzia capituligera (whole plant), Trachelospermum jasminoides (Lindl.) Lem. (whole plant), Elsholtzia strobilifera Benth. (whole plant), Agrimonia pilosa var. nepalensis (D. Don) Nakai (whole plant) and Aster poliothamnus Diels (whole plant) exhibited a significant inhibitory activity against AR. Particularly, Inula helianthus-aquatilis C. Y. Wu ex Ling. showed seven times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

• The Korea Journal of Herbology
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• v.29 no.6
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• pp.35-43
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• 2014

Objectives : Official Arisaematis Rhizoma is described only three species, Arisaema amurnse, Arisaema erubescens, and Arisaema heterophyllum, in national Pharmacopoeia. However, other Arisaema species, Arisaema ringens, Arisaema takesimense and Arisaema serratum, also have been distributed as an inauthentic Arisaematis Rhizoma in the herbal market. To develop a reliable molecular authentication method for Arisaematis Rhizoma in species level, we analyzed DNA barcode regions using six Arisaema species. Methods : Thirty-eight samples of six Arisaema plants species (A. amurense, A. amurense f. serratum, A. heterophyllum, A. takesimense, and A. serratum) were collected from different habitate and nucleotide sequences of DNA barcode regions (rDNA-ITS, matK, and rbcL gene) were analyzed after PCR amplification. The species-specific sequences and phylogenetic relations were estimated using entire sequences of three DNA barcodes based on the analysis of ClastalW and UPGMA, respectively. Results : The comparative analysis of DNA barcode sequences were revealed inter-species specific nucleotides to distinguish the medicinal plant of Arisaema Rhizoma in species levels excluding between A. amurense and its subspecies (A. amurense f. serratum) and A. takesimense and A. serratum, respectively. However, we obtained sequence differences enough to discriminate authentic and inauthentic Arisaematis Rhizoma. Therefore, we suggest that these SNP type molecular genetic markers were an reliable method avaliable to identify official herbal medicines. Conclusions : These marker nucleotides could be useful to identify the official herbal medicines by providing definitive information that can identify original medicinal plant and distinguish from inauthentic adulterants and substitutes.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.123-128
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• 2008

Glehnia littoralis (Umbelliferae), a perennial herb distributed along the coastline of northern Pacific countries, is the medicinal plant used traditionally for treatment of various diseases. This review focuses on the various pharmacological activities of Glehnia littoralis for understanding about its traditional medicinal applications, medicinal uses in the modern society, and potentials for drug development Glehnia littoralis was reported to have anti-oxidant, anti-tumor, anti-amnesic, blood circulation-promoting, immunomodulatory, anti-microbial, and allelopathic activities. However, their mechanisms remain to be clarified. Because Glehnia littoralis has been prescribed in traditional Oriental medicine as a tonic herb, Glehnia littoralis can be better than other chemical drugs and medicines which exert the equal pharmacological activities. Although the activities of Glehnia littoralis are not specifically high-potent with unique mode of action, it may turn out that it can be beneficial to exert multiple pharmacological activities. In view of low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of Glehnia littoralis, it needs to be prudent to evaluate its properties and applications further.

• Plant Resources
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• v.7 no.2
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• pp.155-158
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• 2004

Activate charcoal (AC) can be utilized as a soil conditioner in agricultural crop areas. This study was conducted to investigate the effect of AC on growth and yield of Zingiber mioga ROSC as affected by different amounts of AC. The results obtained are summarized as follows. Growth characteristics including plant height and leaf length were the highest when activated charcoal added with 10-30%, suggesting that optimum amount of activated charcoal was ranged from 10 to 30%. Growth and enlargement of the root were improved by 10% AC with higher rhizome length and weight.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2021.04a
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• pp.10-10
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• 2021

Natural products have been used as drugs and cosmetics due to their bioactivity and their biochemical diversity. Natural products usually refer to secondary metabolites produced by various living organisms including marine animals, insects, microbes, amphibians, and plants. These secondary metabolites, which usually have molecular weights less than 2,000 amu, are unnecessary for survival, development, growth, and reproduction but play major roles in plant defense systems against other species. These secondary metabolites such as lignans, flavonoids, monoterpenes, and phenylethanoid glycosides showed various biological activities like anti-oxidant behavior, anti-cancer properties, neuroprotective properties, and so forth. Thus, isolation and elucidation of secondary metabolites from living organisms is of great significance to human life.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.19-31
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• 2008

Names attributed to villages varies from governmental administrative division to simple modest names called from the habitants. Actually, scarce names only called from the habitants remains today. While these names reflect abundant cultural, social and historical aspects we made this research based on those nominations related only to Korean traditional medicine(KTM). We could find that the most KTM related village name was famine relieve or/and medicinal plant designation like Puerariae village. Also there was names of doctors like Dasan. Another big portion was from the medicinal mineral waters like Yakbawegol which said has the properties for dermatologic desease. We suggest this study may use as a clue in the field of KTM history research.