• Title/Summary/Keyword: Pin to pin

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Pin1 Promoter rs2233678 and rs2233679 Polymorphisms in Cancer: A Meta-analysis

  • Zhu, Yan-Mei;Liu, Jing-Wei;Xu, Qian;Yuan, Yuan
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5965-5972
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    • 2013
  • PIN1 is one member of the parvulin PPIase family. By controlling Pro-directed phosphorylation, PIN1 plays an important role in cell transformation and oncogenesis. There are many polymorphisms in the PIN1 gene, including rs2233678 and rs2233679 affecting the PIN1 promoter. Recently, a number of case-control studies were conducted to investigate the association between PIN1 gene rs2233678 and rs2233679 polymorphism and cancer risk. However, published data are still conflicting. In this paper, we summarized data for 5,427 cancer cases and 5,469 controls from 9 studies and attempted to assess the susceptibility of PIN1 gene polymorphism to cancers by a synthetic meta-analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the relationship. All analyses were performed using Stata software. Our results suggested that rs2233678 represented a protective factor in overall analysis (CC vs GG: OR= 0.697, 95%CI: 0.498-0.976; CG vs GG: OR=0.701, 95%CI: 0.572-0.858; Dominant model: OR= 0.707, 95%CI: 0.590-0.847; C allele vs G allele: OR=0.734, 95%CI: 0.623-0.867) and especially for squamous cell carcinoma of the head and neck, lung cancer and breast cancer in Asians and Caucasians. The rs2233679 polymorphism was significantly associated with decreased cancer risk in overall analysis (CT vs CC: OR=0.893, 95%CI=0.812-0.981; Dominant model: OR=0.893, 95%CI=0.816-0.976; T allele vs C allele; OR=0.947, 95%CI=0.896-1.000) and especially in Asians. In conclusion, our meta-analysis suggested that -842G>C (rs2233678) and -667C>T (rs2233679) may contribute to genetic susceptibility for cancer risks. Further prospective research with larger numbers of worldwide participants is warranted to draw comprehensive and firm conclusions.

Low Phase Shift Attenuator Using the Half-Moon Radial Stub (반달 모양의 방사형 동조 스터브를 이용한 저위상 변화 감쇠기의 설계)

  • 윤종만;양기덕;김민택;박익모;신철재
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.8 no.5
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    • pp.452-461
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    • 1997
  • In this paper, we present a computer-aided design(CAD) technique for minimizing the phase shift in microstrip PIN diode attenuators due to the junction capacitance in the equivalent circuit model of PIN diode. Microstrip PIN diode attenuators use the characteristics which the reactance of microstrip line changes from inductive to capacitive as the frequency sweeps across the band. Microstrip PIN diode attenuator designed utilizes the quarter-wavelength transmission line terminating with the half-moon radial stub, which is designed for negligible phase shifting effect over the intersted bandwidth. The attenuator has similar phase shift at 0 dB and 10 dB of attenuation within average $1.27^{\circ}$ between 1.2GHz and 1.9GHz. The input and output return losses between 1.4 GHz and 1.9 GHz are less than 10 dB over the attenuation range of 0 dB and 10 dB.

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Properties of Rice Flour Prepared with Roll Mill and Pin Mill after Tempering (조질 후 Roll Mill과 Pin Mill의 제분 및 쌀가루의 특성)

  • 김형열;이병영;유효숙;최중경;함승시
    • Food Science and Preservation
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    • v.6 no.3
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    • pp.313-318
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    • 1999
  • The Properties of rice flour and consumed electricity to make rice flour were compared among three different process ; 1. roll mill after soaking rice in water, 2. roll mill after tempering, 3. try pin mill. When rice was milled by roll mill and pin-milled after tempering for 10 hrs(TRPMR), consumed electricity and moisture content of rice flour were the least. Particle size of rice flour prepared with TRPMR was 87.4% of 100 mesh or more which was the highest number among the rice flour prepared using different processes. Gelatinization temperature of the rice flour was 63.2$^{\circ}C$ and was 1.3$^{\circ}C$ lower than that of rice flour prepared with other processes. Viscosity of the rice flour prepared by TRPMR was the least. Whiteness of the rice flour prepared by TRPMR was similar to that of wheat flour.

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A $\pi$-type Variable Attenuator with Low Phase Shift (저위상 변화 특성을 갖는 $\pi$-형 가변 감쇠기)

  • Park, Ung-Hee;Ahn, Gil-Cho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.10
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    • pp.2066-2070
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    • 2009
  • A voltage controlled attenuator using a PIN diode and two resistors of the $\pi$-type fixed attenuator is described in this paper. The proposed variable attenuator operating for a fixed attenuation range has a good input VSWR and a low intermodulation signal. For the low phase shift, a PIN diode is connected with open stub for the purpose of phase compensation. The stub for phase compensation is calculated by the Deloach method and the related circuit theory. This attenuator is easily fabricated on the microstrip and can be normally used in fine control circuits within small attenuation range. The fabricated attenuator for 2110~2170 MHz frequency band has about 4 dB of an attenuation range, $2^{\circ}$ of phase variance, and -20 dB of S11 according to the input voltage from 0 to 2.7 V.

Numerical Study on Heat Transfer and Flow Characteristics of Pin Fin with Swept Airfoil Shape Vortex Generator (후퇴익형 형상의 와류발생기가 있는 핀휜 유동의 전열 및 유동 특성 분석에 관한 수치적 연구)

  • Lee, Changhyeong;Oh, Yeongtaek;Bae, Jihwan;Lee, Deukho;Kim, Kuisoon
    • Journal of the Korean Society of Propulsion Engineers
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    • v.23 no.4
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    • pp.28-34
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    • 2019
  • In this study, pin-fin arrays, which are widely used for cooling turbine blades, were studied. The vortex generator in pin-fin arrays is located in front of the circular tube. The cross-section of the vortex generator is NACA-9410. The purpose of this study is to analyze heat transfer performance and flow characteristics of pin-fin arrays. The position of vortex generator is changed with the vertical flow direction on the bottom wall. Pin-fin arrays were calculated with 6000, 10000 and 15000 Reynolds number. The commercial program ANSYS v18.0 CFX and the turbulence model $k-{\omega}$ SST were used. As a result, the heat transfer performance increased up to 5.8% and pressure loss increased less than 1%.

A Multi-Polarization Reconfigurable Microstrip Antenna Using PIN Diodes (PIN 다이오드를 이용한 다중 편파 재구성 마이크로스트립 안테나)

  • Song, Taeho;Lee, Youngki;Park, Daesung;Lee, Seokgon;Kim, Hyoungjoo;Choi, Jaehoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.5
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    • pp.492-501
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    • 2013
  • In this paper, a multi polarization reconfigurable microstrip antenna that can be used selectively for four polarizations(vertical polarization, horizontal polarization, right hand circular polarization, left hand circular polarization) at the S-band is presented. The proposed antenna consists of four PIN diodes and a microstrip patch with a cross slot and a circular slot and is fed by utiliting electromagnetic coupling between the microstrip patch and the feed line. The proposed antenna has a DC bias network to supply DC voltage to each PIN diode and the polarization can be determined by controlling the ON /OFF states of four PIN diodes. The fabricated antenna has a VSWR below 2 in the vertical polarization(3.17~3.21 GHz), the horizontal polarization(3.16~3.20 GHz), the left hand circular polarization (3.08~3.19 GHz), and the right hand circular polarization(3.10~3.2 GHz) frequency bands. The designed antenna has the cross polarization level higher than 20 dB, a gain over 5 dBi for the linear polarization states, and 3 dB axial ratio bandwidth wider than 50 MHz in the circular polarization states.

Impact of Milling Method on Quality Parameters of Waxy Sorghum Flour (제분방법에 따른 찰수수 가루의 품질 특성)

  • Ryu, Bog-Mi;Kim, Chang-Soon
    • Korean journal of food and cookery science
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    • v.29 no.2
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    • pp.129-135
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    • 2013
  • The objective of this research was to investigate physicochemical properties of waxy sorghum flours by different milling methods (pin mill and ultra fine mill). Four different sorghum flours were used for the experiments ; PWS (pin milled whole sorghum flour), PS (pin milled sorghum flour without bran), UFWS (ultra fine milled whole sorghum flour), UFS (ultra fine milled sorghum flour without bran). The contents of crude ash and total dietary fiber were the highest in PWS. Amylose content of pin milled sorghum flour was higher than that of ultra fine milled flour. The mean particle size of pin milled flours was six times lager than ultra fine milled flours. The L values of UFS and UFWS were higher than those of PS and PWS, whereas a and b values were higher in PWS. The water binding capacity was highest in UFWS, and solubility was higher in PS and UFS. Swelling power of flours was highest in UFS. The damaged starch content was higher in PS and UFS, which means damaged starch of sorghum flours significantly affected by polishing than milling method. The pasting properties were higher in the pin milled flours. Initial pasting temperature of pin milled flour was ranging from 70.5 to $73.1^{\circ}C$, which are higher than ultra fine milled flour ($68.6^{\circ}C$). The contents of total polyphenol were higher in PWS and UFWS than those of PS and UFS, there was no difference between the two milling methods. The results of this study indicate that physicochemical properties of sorghum flour were affected by milling methods as well as bran.

A K-band Hair-pin Oscillator Using a Frequency Doubler (주파수 체배기를 이용한 K-Band용 Hair-pin 발진기)

  • 현안선;김훈석;김종헌;이종철;김남영;정원채;홍의석
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.9 no.6
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    • pp.833-842
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    • 1998
  • In this paper, a K-band oscillator which is composed of a hair-pin resonator, a GaAs MESFET, and a frequency doubler, is suggested, implemented by HMIC(Hybrid Microwave Integrated Circuits) form, and characterized for its microwave performance. A $\lambda_g$/4 open stub is used in frequency doubler to suppress the fundamental frequency of 9 GHz which is the output of the hair-pin resonator oscillator and output matching network is optimized for its second harmonic freuency of 18 HGz. For the oscillator, the output power of -0.83 dBm, the fundamental frequency suppression of -23 dBc, and phase noise of -86 dBc/Hz at 18.20 GHz are obtained.

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COMPARISON OF THE ABRASIVENESS OF CEROMERS ON ENAMEL AND GOLD ALLOY (Ceromer의 법랑질 및 금합금에 대한 마모도 비교)

  • Jung Hee-Kyung;Yang Hong-So
    • The Journal of Korean Academy of Prosthodontics
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    • v.39 no.1
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    • pp.96-104
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    • 2001
  • This study was performed to compare the abrasiveness and wear resistance of several restorative materials occluding enamel and gold alloy. Intact labial surface of bovine incisor and the plain portion of type III gold alloy were used as plate specimens, and pin specimens were fabricated using $Artglass^{(R)},\;Targis^{(R)},\;Sculpture^{(R)}$. After two-body wear test using pin and plate model, amount of vertical height loss of plate and pin specimens were measured and statically analyzed. The amount of vertical height loss of plate specimens against pin specimens were measured by a roughness measurement instrument. The amount of vertical height loss of pin specimens against plate specimens were measured by an image analyzing program after taking scanning electron micrographs of pin specimens. The results were as following. 1. As fir the amount of enamel wear. gold group showed least amount of wear. There was no significant difference among Sculpture, Targis and Artglass groups(p<0.05). 2. As for the amount of gold wear Sculpture group standed first and Targis and Artglass group followed respectively, and there was significant difference between Sculpture and Artglass groups(p<0.05). 3. As for the amount of restorative materials against enamel, Artglass group showed greatest, and there was no significant difference among gold. Sculpture, Targis groups(p<0.05). 4. As for the amount of restorative materials against gold, Artglass group standed first and Targis and Sculpture group followed respectively, and there was significant difference among each groups(p<0.05).

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