• Proceedings of the Korea Concrete Institute Conference
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• 2006.11a
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• pp.213-216
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• 2006

The designer has difficulty due to inadequacy of provisions in the domestic design code and lack of understanding for behavior of D-region. The reinforced concrete pi(${\pi}$)-shaped RC rahmen bridge consists of various failure mechanisms as the crushing or splitting from compression concrete, and shearing failure under the loading plate. However, predicting those failure mechanisms is very difficult. In this study, the pi(${\pi}$)-shaped RC rahmen bridge is analyzed and designed by using strut-tie model. Adequacy for the application of strut-tie model is verified by comparison with the way used in current design practice. As a result that designing the structures should be maked a comparison between strut-tie model and current conventional design method.

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.164-165
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• 2000

There has recently been a considerable amount of interest in two-photon(TP) processes because of their applications to 3-D optical data storage and imaging, up-conversion lasing, and optical power limiting. Recently, the role of Dithienothlophene(DTT) as $\pi$-center of two-photon absorption(TPA) molecules was reported to give a large enhancement of TPA, compared with the benzeniods counterparts.$^{[1]}$ In this report, we carried out two experiments to investigate nonlinear optical absorption of the molecules in which central DTT is attached through conjugation to either a D/D or a D/A pair at the ends, forming a D-$\pi$-D(1 and 3) or D-$\pi$-A(2 and 4) sequence(Fig.1). All the samples were prepared in solutions with the same molar concentration. (omitted)

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.9
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• pp.1446-1451
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• 2013

The quality characteristics of pork patty prepared with chitosan containing preservatives during storage at $4^{\circ}C$ were investigated to improve its functional property and shelf life using food preservatives of natural origin (PI; 0.1% chitosan, 2.5% citric acid, 100 ppm grapefruit seed extract, 0.2% adipic acid, 0.1% Cinnamomum extract, D.W. 97.09% and PII; 0.1% chitosan, 2.5% citric acid, 100 ppm grapefruit seed extract, 0.2% adipic acid, 0.1% Lysimachia christinae Hance extract, D.W. 97.09%). The sensory qualities (taste, appearance, texture and overall acceptability) of patties preserved with PI (1, 3 and 5%) and PII (1, 3 and 5%) were also investigated. The taste and overall acceptability of patties prepared with 1% PI and 1% PII were higher than those of the control. The DPPH radical scavenging activities of the control, 1% PI and 1% PII treated patties were 13.54%, 21.78% and 14.07%, respectively. The total aerobes and coliform count of patties preserved with 1% PI were $10^4$ CFU/g and $10^2$ CFU/g, respectively, after 10 days storage at $4^{\circ}C$. Cooking loss from 1% PI and 1% PII treated patties was lower than that of from the control. Water holding capacity was the highest for 1% PI (65.84%), followed by 1% PII and then the control. The shelf life of patties prepared with 1% PI and 1% PII was extended by about 5 days relative to the control at $4^{\circ}C$.

• Journal of the Korean Vacuum Society
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• v.17 no.5
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• pp.375-380
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• 2008

We have investigated the low-dimensional nanostructures produced by adsorption of triangular Co coplexed dipyrromethane(DPM-trimer, Fig. 1) on graphite surface by using scanning tunneling microscope. DPM-trimer deposition on the graphite surface leads to the formation of long 1-D molecular wires and 2-D hexagonal patterns. We analyzed the heights and structures of 1-D molecular wires and 2-D hexagonal patterns. The 1-D molecular wires were formed 'edge-on' alignments on graphite surface result of continuos $\pi-\pi$ stacking interactions. The other case of 2-D hexagonal patterns were formed 'face-on' alignments on graphite surface.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.30A no.9
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• pp.6-13
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• 1993

In is well-known that system performance in the high speed digital radio communication system is usually deteriorted due to the frequency selective fading distortion. In this paper, bit error rate(BER) performance by the reception phase error in cellular mobile communication systems is derived and analyzed. The system is modeled as a frequency selective fast Rayleigh fading channel corrupted by additive white gaussian noise(AWGN) and co-channel interference(CCI). Our numerical results show that for the 24KBaud(48Kb/s) $\pi$/4-DQPSK operated at carrier frequency 800 MHz and C/I<20 dB, the BER will be dominated by CCI if the vehicular speed is below 100 Km/h. The results show that performance, when reception phase error is below $\pi$/12, is deterioreted less than 3 dB, and that performance, when reception phase error is above $\pi$/12, is degraded over 3 dB.

• Analytical Science and Technology
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• v.6 no.1
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• pp.39-45
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• 1993

We have examined Raman spectra of cis-peptide model complex, diketopiperazine in water and $D_2O$ with 320 nm through 218 nm excitation. Our study examines assignment of the resonance enhanced amide vibrations and characterizes their enhancement mechanism. Three resonance enhaned cis-peptide marker bands were observed in aqueous solution at 1676, 1533 and $806cm^{-1}$, which were assigned to the cis-amide I, II and S band, respectively. The $1533cm^{-1}$ amide II band, which is almost pure C-N stretching, was most dominant in water and shifted to $1520cm^{-1}$ upon N-deuteration. This band will be probably a potential probe band for cis-peptide moieties in proteins. The excitation profile data and an Albrecht A-term fit indicated that the cis-peptide vibrations derive their intensities from the 188 nm cis-peptide ${\pi}-{\pi}^*$ electronic transition. We Propose that the geometry of cis-peptide ${\pi}^*$ excited state is C-N bond displacement relative to that of electronic ground state.

• Macromolecular Research
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• v.17 no.9
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• pp.672-681
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• 2009

A series of inert and photo-stable Er(III)-encapsulated complexes based on ${\pi}$-extended dendritic anthracene ligands bearing G3-aryl-ether dendron ([G3-AnX]-$CO_2H$), which retain different ${\pi}$-bridging systems, such as single (X= S), double (X= D) and triple (X= T) bonds was designed and synthesized to establish the structure-property relationship. The near infrared emission intensities of Er(III)-encapsulated complexes were enhanced dramatically by increasing the ${\pi}$-conjugated extension of anthracene ligands. The time-resolved luminescence spectra show monoexponential decays with a lifetime of $2.0{\sim}2.4ms$ for $Er^{3+}$ ions in thin films, and calculated intrinsic quantum yields of $Er^{3+}$ ions are in the range of $0.025{\sim}0.03%$. As a result, all Er(III)-encapsulated dendrimer complexes exhibit the near IR emission with the following order: $Er^{3+}-[G3-AnD]_3$(terpy) > $Er^{3+}-[G3-AnS]_3$(terpy) ${\approx}$ $Er^{3+}-[G3-AnT]_3$(terpy), because $Er^{3+}-[G3-AnD]_3$(terpy) has a higher relatively spectral overlap J value and energy transfer efficiency. In addition, the lack of detectable phosphorescence and no significant spectral dependence of the ${\pi}$-extended anthracene moieties on the solvent polarity support energy transfer from their singlet state to the central $Er^{3+}$ ion taking place in $Er^{3+}-[G3-AnX]_3$(terpy).

• Bulletin of the Korean Chemical Society
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• v.29 no.3
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• pp.656-662
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• 2008

Antagonists of the d -opioid receptor are effective in overcoming resistance against analgesic drugs such as morphine. To identify novel antagonists of the d -opioid receptor that display high potency and low resistance, we performed 3D-QSAR analysis using chemical feature-based pharmacophore models. Chemical features for d -opioid receptor antagonists were generated using quantitative (Catalyst/HypoGen) and qualitative (Catalyst/HipHop) approaches. For HypoGen analysis, we collected 16 peptide and 16 non-peptide antagonists as the training set. The best-fit pharmacophore hypotheses of the two antagonist models comprised identical features, including a hydrophobic aromatic (HAR), a hydrophobic (HY), and a positive ionizable (PI) function. The training set of the HipHop model was constructed with three launched opioid drugs. The best hypothesis from HipHop included four features: an HAR, an HY, a hydrogen bond donor (HBD), and a PI function. Based on these results, we confirm that HY, HAR and PI features are essential for effective antagonism of the d -opioid receptor, and determine the appropriate pharmacophore to design such antagonists.

• Molecules and Cells
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• v.41 no.6
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• pp.532-544
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• 2018

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. In order to investigate a new treatment fot GIST, we hypothesized the effect of miR-374b targeting PTEN gene-mediated PI3K/Akt signal transduction pathway on proliferation and apoptosis of human gastrointestinal stromal tumor (GIST) cells. We obtained GIST tissues and adjacent normal tissues from 143 patients with GIST to measure the levels of miR-374b, PTEN, PI3K, Akt, caspase9, Bax, MMP2, MMP9, ki67, PCNA, P53 and cyclinD1. Finally, cell viability, cell cycle and apoptosis were detected. According to the KFGG analysis of DEGs, PTEN was involved in a variety of signaling pathways and miRs were associated with cancer development. The results showed that MiR-374b was highly expressed, while PTEN was downregulated in the GIST tissues. The levels of miR-374b, PI3K, AKT and PTEN were related to tumor diameter and pathological stage. Additionally, miR-374b increased the mRNA and protein levels of PI3K, Akt, MMP2, MMP9, P53 and cyclinD1, suggesting that miR-374b activates PI3K/Akt signaling pathway in GIST-T1 cells. Moreover, MiR374b promoted cell viability, migration, invasion, and cell cycle entry, and inhibited apoptosis in GIST cells. Taken together, the results indicated that miR-374b promotes viability and inhibits apoptosis of human GIST cells by targeting PTEN gene through the PI3K/Akt signaling pathway. Thus, this study provides a new potential target for GIST treatment.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2011.03a
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• pp.63-63
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• 2011

The donor-${\pi}$-acceptor (D-${\pi}$-A) chromophoric dye system has received great attention in variety fields such as electroluminescent materials, sensors and optoelectronic devices. There are many research activities focused on the development for abovementioned application materials with the high-performance properties. In the previous work, we are reported that novel D-${\pi}$-A dye, 2-[4-(9H-carbazol-9-yl)benzylidene]-2,3-dihydroinden-1-one, is successfully attained and exhibited a positive fluorescence solvatochromism. In this work, the molecular structure and packing geometry of 2-[4-(9H-carbazol-9-yl)benzylidene]-2,3-dihydroinden-1-one was discussed by their conformational structure. Their single yellow prism crystal having approximate dimensions of $0.30{\times}0.10{\times}0.10$ mm was carried out with a Rigaku RAXIS RAPID imaging plate area detector with graphite monochromated $CuK_{\alpha}$ radiation. Their crystal structure were solved by using the CrystalStructure crystallographic software package.