• 대한전기학회:학술대회논문집
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• 대한전기학회 2000년도 하계학술대회 논문집 D
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• pp.3222-3226
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• 2000

In this study, the variations of human physiological signals(EEG and ERG) were measured on a various optic stimulation. From the analysis of the physiological signals, it was cleared that the optimum intensity of light exits at its sensing.

• 융합신호처리학회논문지
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• 제3권1호
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• pp.27-32
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• 2002

본 논문에서 제안한 텔레미트리 시스템은 생체신호를 중거리로 전송하기 위한 RF 송신기와 전자파 간섭의 영향이 없는 광을 매체로한 수신기이다. 텔레미트리 시스템은 of 65$\times$125$\times$45mm크기이며, RF 송신부, 광 수신부와 생체신호 처리를 위한 CMOS 칩으로 구성되어 있다. 제안된 텔레메트리 장점은 전자파에 노출을 최소화하면서 중거리(50m) 텔레메트리가 가능하여, 자유로운 상태에서의 모니터링이 가능하다. 관측 시스템은 실시간 처리를 위해 dual-processor구조로 설계했다. 본 연구에서는 1 채널 360Hz, 16 Bits의 심전도 데이터를 1.42초 간격으로 실시간 웨이브렛 변환할 수 있었다.

• 한국정보통신학회논문지
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• 제18권1호
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• pp.155-161
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• 2014

본 연구는 사용자의 감성을 효율적으로 유도하는 실시간 감성 이미지 콘텐츠 플레이어를 제안한다. 감성 이미지 콘텐츠 플레이어는 실시간으로 이미지 콘텐츠의 명도, 채도에 변화를 줌으로써 사용자의 감성에 따라 효율적으로 감성 유도가 가능하도록 설계하였다. 감성인식 부분은 자율신경계 기반의 맥파, 피부온도, 피부저항의 생체신호를 활용하였다. 사용된 감성 콘텐츠 이미지는 국제적 정서체계(IAPS)에서 분류된 9가지 감성영역의 이미지를 적용하였다. 실험결과로 감성 이미지 콘텐츠 플레이어를 통해 이미지의 감성 상태에 맞는 사용자의 감성이 10% 더 정확하게 유도되었다. 감성 콘텐츠 플레이어는 실시간으로 감성 반영을 통해 사용자와 콘텐츠간의 감성적 교감을 증대시킬 것으로 기대된다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.67-71
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• 2007

최근 고령 인구의 증가에 따른 헬스 케어 수요가 증가하고 있고 환자뿐만 아니라 일반인들에게서도 헬스 케어 모니터링에 대한 요구가 급증하고 있다. 또한 의료 서비스를 제공받으려는 대상자의 불편을 최소화하고, 지속적인 모니터링을 통한 헬스 케어가 가능할 수 있는 의료 기술과 의료 정보서비스에 대한 수요도 늘어나고 있는 추세이다 본 논문에서는 헬스 케어를 위한 무선 생체 신호 모니터링 시스템을 구현하였다. 구현된 시스템은 생세 신호 측정부와 무선 통신부로 구성된 센서 노드(sensor node)와 원격 시스템의 모니터링 프로그램으로 구성된다. 센서 노드에서는 심전도, 혈압, 맥파, 동맥혈산소포화도, 심박수를 측정할 수 있고 블루투스 기술을 이용하여 무선 전송을 하여 모니터링 시스템에서 실시간 무선 모니터링이 가능하도록 구현하였다.

• 한국정보통신학회논문지
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• 제12권8호
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• pp.1401-1407
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• 2008

최근 고령 인구의 증가에 따른 헬스 케어 수요가 증가하고 있고 환자뿐만 아니라 일반인들에게서도 헬스 케어 모니터링에 대한 요구가 급증하고 있다. 또한 의료 서비스를 제공받으려는 대상자의 불편을 최소화하고, 지속적인 모니터링을 통한 헬스 케어가 가능할 수 있는 의료 기술과 의료 정보 서비스에 대한 수요도 늘어나고 있는 추세이다. 본 논문에서는 헬스 케어를 위한 무선 생체신호 모니터링 시스템을 구현하였다. 구현된 시스템은 생체신호 측 정부와 무선 통신부로 구성된 센서 노드(sensor node)와 원격 시스템의 모니터링 프로그램으로 구성된다. 센서 노드에서는 심전도, 혈압, 맥파, 동맥혈산소포화도, 심박수를 측정할 수 있고 블루투스 기술을 이용하여 무선 전송을 하여 모니터링 시스템에서 실시간 무선 모니터링이 가능하도록 구현하였다.

• Journal of Life Science
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• 제11권2호
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• pp.94-98
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• 2001

Type I signal peptidase cleaves the signal sequence from the amino terminus of membrane and secreted proteins afters these protein insert across the membrane. This enzyme serves as a potential target for the development of novel antibacterial agents due to its unique physiological and biochemical properties. Despite considerable research, the signal peptidase assay still remains improvement to provide further understanding of the mechanism and high-throughput inhibitor screening of this enzyme. In this paper, three known signal peptidase assays are tested with an E. coli D276A mutant signal peptidase to distinguish the sensitivity of each assays. In vitro assay using the procoat synthesized by in vitro transcription translation shows that the D276A signal peptidase I was inactive while in vivo processing of pro-OmpA expressed in the temperature-sensitive E. coli strain IT41 as well as in vitro assay using pro-OmpA nuclease A substrate show that D276A signal peptidase I has activity like wild-type signal peptidase. These results suggest that in vitro assay using the pro-OmpA nuclease A and in vivo pro-OmpA processing assay are more sensitive monitors than in vitro assay using the pro-coat. In conculsion, caution should be used when interpreting the in vitro results using the procoat.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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• pp.1.1-5
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• 1994

In the single sweep record of event-related potential (ERP), the peak latency of P300, which is one of the most prominent positive peaks in the ERP record, might fluctuate according to the recording conditions. The fluctuation of the peak latency (measurement fluctuation) is the summation of the fluctuation caused by physiological factor (physiological fluctuation) and one by noise of background EEG (noise fluctuation). We propsed a method for estimating the interval of the physiological fluctuation based on a limited number of single sweep records. The noise fluctuation was estimated by using the relationship between the signal-to-noise (SN) ratio and the noise fluctuation based on the P300 model and the background EEG model. The interval estimate of the physiological fluctuation were obtained by subtracting the interval estimate of the noise fluctuation from that of the measurement fluctuation. The proposed method was tested by using simulation data of ERP and applied to actual ERP and data of normal subjects, and gave satisfactory results.

• International Journal of Contents
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• 제10권2호
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• pp.47-58
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• 2014

Physiological signals provide important clues in the diagnosis and prediction of disease. Analyzing these signals is important in health and medicine. In particular, data preprocessing for physiological signal analysis is a vital issue because missing values, noise, and outliers may degrade the analysis performance. In this paper, we propose PhysioCover, a system that can recover missing values of physiological signals that were monitored in real time. PhysioCover integrates a gradual method and EM-based Principle Component Analysis (PCA). This approach can (1) more readily recover long- and short-term missing data than existing methods, such as traditional EM-based PCA, linear interpolation, 5-average and Missing Value Singular Value Decomposition (MSVD), (2) more effectively detect hidden variables than PCA and Independent component analysis (ICA), and (3) offer fast computation time through real-time processing. Experimental results with the physiological data of an intensive care unit show that the proposed method assigns more accurate missing values than previous methods.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 1999년도 춘계학술발표논문집 논문집
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• pp.221-230
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• 1999

Automobile horn's psychoacoustic characteristic and significance as a anturalistic signal of danger makes it a valuable auditory stimulus to study such psychophysiological responses as startle, orienting and defense reactions. However, comparison and differentiation of physiological responses to commercially available horns is a complicated task due to small contrast of technical features of horns and influence of such processes as habituation on physiological outcome with increased number of auditory stimulation trials. In the study on 10 college students we performed comparative analysis of tonic and phasic reactivity of physiological responses mediated by autonomic nervous system in order to identify role of habituation and decrement of autonomic responsivity, as well as possibility o differentiate subjectively most and least preferred and subjectively more appropriate horns according to physiological manifestations. It was showed that electrodermal and cardiovascular reactivity have concurrent patterns of adaptation to repeated stimulation, namely skin conductance variables habituated, cardiac reactivity failed to show signs of habituation, while vascular component of response were facilitated demonstrating marked sensitization. Differentiation of Physiological responses to horns with respect to their subjective rating scores was possible, however electrodermal reactivity was effective only at the first block of trials, while phasic and tonic cardiovascular reactivity differentiate responses during whole course of experiment. There are discussed possible autonomic mechanisms involved in mediation of observed results.

• Fibers and Polymers
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• 제6권1호
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• pp.89-94
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• 2005

The purpose of this study is to offer acoustical database of warp knitted fabrics by investigating frictional sound properties and physiological responses according to structural parameters such as construction, lap form, and direction of mutual guide bar movement. Fabric sounds of seven warp knitted fabrics are recorded, and Zwicker's psychoacoustic param­eters - loudness(Z), sharpness(Z), roughness(Z), and fluctuation strength(Z) - are calculated. Also, physiological responses evoked by frictional sounds of warp knitted fabrics are measured such as electroencephalogram (EEG), the ratio of high fre­quency to low frequency (HF/LF), respiration rate (RESP), skin conductance level (SCL), and photoplethysmograph (PPG). In case of constructions, frictional sound of sharkskin having higher loudness(Z) and fluctuation strength(Z) increases RESP. By lap form, open lap has louder and larger fluctuating sound than closed lap, but there aren't significant difference of physi­ological responses between open lap and closed lap. In direction of mutual guide bar movement, parallel direction evokes bigger changes of beta wave than counter direction because of its loud, rough, and fluctuating sound. Fluctuation strength(Z) and roughness(Z) are defined as important factors for predicting physiological responses in construction and mutual guide bar movement, respectively.