• 대한인간공학회지
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• 제26권1호
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• pp.11-18
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• 2007

The physiological and biochemical responses of healthy men and women to life stress were measured in order to temperature, blood pressure (BP), heart rate (HR) and galvanic skin response (GSR) were selected as physiological stress indices and salivary cortisol level was used as a biochemical stres biomarker. Twenty six (male 14 and female 13) colege students were participated in the experiment. Female showed the significant higher value of salivary cortisol level (p<0.01), diastolic BP (p<0.01), and HR (p<0.01) than male. The difference of skin temperature between forehead and fingertip correlated significantly with salivary cortisol level (p<0.01). The LF(low frequency)/HF(high frequency) ratio of HRV also correlated significantly with salivary cortisol level (p<0.01). However, BP, HR and GSR corelated insignificantly with salivary cortisol level. We suggest that LF/HF ratio of HRV and skin temperature may be good indices for the assessment of life stress, and may apply to measure the stress level of individual in real time.

• 설비공학논문집
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• 제28권6호
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• pp.217-223
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• 2016

In this study, we investigated the operating method of a driver for an air conditioning system according to the temperature difference between the indoor and outdoor environments of a car parked outside during the summer. Researchers of this study suggest the comfort mode of a car air conditioner to improve the thermal comfort of the driver, thereby maintaining longer comfort. This study separately, analyzed temperatures on a cloudy day and sunny day. The results showed the car indoor heat environment and physiological results (EEG, ECG) of the subject. It showed a difference of the car indoor heat environment by weather with the difference also appearing in the physiological response of the subject. In conclusion, in this paper, on the basis of the physiological response of a subject, a comfortable algorithm of automobile air conditioner is being suggested.

• 한국패류학회지
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• 제30권3호
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• pp.169-175
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• 2014

PAHs (Polycyclic Aromatic Hydrocarbons: PAHs) is the hydrophobic inorganic material composed of carbon and hydrogen that is easily adsorbed biological organisms in the ocean. Bivalves is the indicator of environment monitoring because of reflect growth, physiological response of bivalve followed their habitat environment. The aim of research is understand the change of oysters (Crassostrea gigas) physiological response under exposed PAHs concentration for control, 1, 10 and $100{\mu}g/L$. We investigated induced immune change response for oyster hemocyte and effect of tissue RNA/DNA ratio for mantle, gill and adductor muscle individually. As a result of experiment change of immune response the oyster hemocyte when exposed PAHs showed that viability and adhesion is no significant difference (ANOVA test, p < 0.05). However phagocytosis decreased under the over $10{\mu}g/L$ of PAHs concentration and ROS increased with the increase of PAHs concentration. The change of RNA/DNA ratio is R/D ratio decreased with the increase of PAH concentration in adductor muscle. However gill and mantle showed no change of R/D ratio with PAHs concentration. The oysters when exposed inorganic pollutant that decreased of physiological condition and damaged protein synthesis of adductor muscle.

• 국제학술발표논문집
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• The 8th International Conference on Construction Engineering and Project Management
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• pp.257-264
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• 2020

Objective: To investigate test-retest reliability and responsiveness of Equivital Lifemonitor and photoplethysmography based wristwatch tools in assessing physiological parameters during a simulated fatigue task. Methods: Ten university students (Mean age, 30.6 ± 1.7 years) participated in this pilot study. Participants were asked to perform a 30-minute of a simulated fatigue task in an experimental setup in a lab. The physiological parameters (e.g., heart rate, heart rate variability, respiratory rate, electrodermal activity, and skin temperature) were measured at baseline and immediately after the fatigue task. An intraclass correlation coefficient (ICC2,1) was used to evaluate the test-retest reliability of each tool in assessing physiological measures. In addition, the responsiveness of each tool to measure changes from baseline to posttest was calculated using a standardized response mean. Results: The Equivital Lifemonitor has shown good to excellent test-retest reliability for the assessment of heart rate (ICC, 0.97), heart rate variability (ICC, 0.86), respiratory rate (ICC, 0.77), and local skin temperature (ICC, 0.76). However, photoplethysmography based wristwatch showed moderate to good test-retest reliability for the assessment of heart rate (ICC, 0.71), heart rate variability (ICC, 0.73), electrodermal activity (ICC, 0.80), and skin temperature (ICC, 0.72). A large standardized response mean (>0.8) indicates that both tools can capture the changes in heart rate, heart rate variability, respiratory rate, skin temperature, and electrodermal activity after a 30-minute of fatigue task. Conclusions: The Equivital Lifemonitor and photoplethysmography based wristwatch devices are reliable in measuring physiological parameters after the fatigue task. Additionally, both devices can capture the fatigue response after a simulated construction task. Future field studies with a larger sample should investigate the sensitivity and validity of these tools in measuring physiological parameters for fatigue assessment at construction sites.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 1999년도 춘계학술발표논문집 논문집
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• pp.11-15
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• 1999

The discrete state theory on emotion postulated that there existed discrete emotions, such as happiness, anger, fear, disgust, and so forth. Many investigators who emphasized discreteness of emotions have suggested that discrete emotions entailed their specific activities in the autonomic nervous system. The purposes of this study were to develop a model of emotion-specific physiological response patterns. The study postulated six emotions (i.e., happiness, sadness, anger, disgust, fear, and surprise) as the basic discrete emotions. Thirty eight college students participated in the present study. Twelve slides (2 for each emotion category) were presented to the subjects in random order. During resting period of 30 s prior to the presentation of each slide, four presentation of each slide, four physiological measures (EEG, ECG, EDA, and respiration) were recorded to establish a baseline. The same physiological measures were recorded while each slide was being presented for 60 s (producing an emotional sate). Then, the subjects were asked to rate the degree of emotion induced by the slide on semantic differential scales. This procedure was repeated for every slide. Based upon the results, a model of emotion-specific physiological response patterns was developed: four emotion (fear, disgust, sadness, and anger) were classified according to the characteristics of EEG and autonomic responses. However, emotions of happiness and surprise were not distinguished by any combination of the physiological measures employed in this study, suggesting another appropriate measure should be adopted for differentiation.

• 스트레스연구
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• 제27권2호
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• pp.199-204
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• 2019

본 연구는 불안민감도가 과제수행과 스트레스 반응에 미치는 영향을 살펴보고, 이 과정에 우울감은 어떠한 영향을 미치는지 확인하였다. 참가자들은 제한된 시간에 암산 문제를 완수하였고, 불안민감도지수와 우울증 선별도구에 응답하였다. 더불어, 실험 전후 참가자들의 코르티졸(Cortisol) 변화량을 확인하였다. 그 결과, 불안민감도가 높은 사람은 과제수행의 정확도가 떨어지고 코르티졸 수치가 유의미하게 상승하였다. 또한, 불안민감도와 우울감이 모두 높은 참가자들이 코르티졸 수치가 가장 크게 상승하였다. 본 연구는 자기보고식 응답에 근거하여 임상증상을 기술하는 것을 넘어 과제수행의 정확도와 생화학적 지표를 함께 제시함으로써, 보다 안정적으로 개인의 불안민감도와 우울감의 관계를 논의하였다는 의의를 지닌다.

• Bulletin of the Korean Chemical Society
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• 제30권10호
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• pp.2309-2317
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• 2009

Depurination, the release of purine bases from nucleic acids by hydrolysis of the N-glycosidic bond, gives rise to alterations of the cell genome. Though cells have evolved mechanisms to repair these lesions, unrepaired apurinic sites have been shown to have two biological consequences: lethality and base substitution errors. 2-Bromopropane (2-BP) is used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organics. In addition, 2-BP has been used as a replacement for chloroflurocarbons and 1,1,1-trichloroethane as a cleaning solvent in electronics industry. However, 2-BP was found to cause reproductive and hematopoietic disorders in local workers exposed to it. Owing to the toxicity of 2-BP, there has been a tendency to use 1-BP as an alternative cleaning solvent to 2-BP. However, 1-BP has also been reported to be neurotoxic in rats. Though $N^7$-guanine adduct of 2-BP has been reported previously, massive depurination of the nucleosides and calf thymus DNA was observed in this study. We incubated the nucleosides (ddG, dG, guanosine, ddA, dA and adenosine) with excess amount 2-BP at the physiological condition (pH 7.4, $37\;{^{\circ}C}$), which were analyzed by HPLC and LC-MS/MS. In addition, the time and dose response relationship of depurination in nucleosides induced by 2-bromopropane at the physiological condition was investigated. Similarly, incubation of calf-thymus DNA with the excess amount 2-BP at the physiological condition was also performed. In addition, the time and dose response relationship of depurination in calf-thymus DNA induced by 2-BP at the physiological condition was investigated. Those results suggest that the toxic effect of 2-BP could be both from the depurination of nucleosides and DNA adduct formation.

• 한국의류산업학회지
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• 제13권6호
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• pp.959-965
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• 2011

The purpose of this study was to evaluate the effect of wearing induced micro current brassiere on the physiological responses of women. Four women participated to wear a different brassiere condition: with and without micro current chips. Subjects were carried out after wearing the induced micro current brassiere for 120minutes. Eardrum temperature, skin temperature, blood pressure, heart rate, thermal perception, humid perception, and comfort perception were obtained. The results were as follows. The brassiere with micro current chips showed better performance on weight loss than the brassiere without micro current chips. Participants in a higher level of BMI were more likely to lose greater weight. Mean skin temperatures decreased with micro current chips. Participants felt more comfortable for walking in micro current brassiere than in brassiere without micro current chips.

• 대한인간공학회지
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• 제31권6호
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• pp.785-791
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• 2012

Objective: The aim of this study was to investigate the correlation between 3D visual fatigue and physiological measures by canonical correlation analysis enabling to categorical correlation. Background: Few studies have been conducted to investigate the physiological mechanism underlying the visual fatigue caused by processing 3D information which may make the cognitive mechanism overloaded. However, even the previous studies lack validation in terms of the correlation between physiological variables and the visual fatigue. Method: 9 Female and 6 male subjects with a mean age of $22.53{\pm}2.55$ voluntarily participated in this experiment. All participants were asked to report how they felt about their health sate at after viewing 3D. In addition, Low & Hybrid measurement test(Event Related Potential, Steady-state Visual Evoked Potential) and for evaluating cognitive fatigue before and after viewing 3D were performed. The physiological signal were measured with subjective fatigue evaluation before and after in watching the 3D content. For this study suggesting categorical correlation, all measures were categorized into three sets such as included Visual Fatigue set(response time, subjective evaluation), Autonomic Nervous System set(PPG frequency, PPG amplitude, HF/LF ratio), Central Nervous System set(ERP amplitude P4, O1, O2, ERP latency P4, O1, O2, SSVEP S/N ratio P4, O1, O2). Then the correlation of three variables sets, canonical correlation analysis was conducted. Results: The results showed a significant correlation between visual fatigue and physiological measures. However, different variables of visual fatigue were highly correlated to respective HF/LF ratio and to ERP latency(O2). Conclusion: Response time was highly correlated to ERP latency(O2) while the subjective evaluation was to HF/LF ratio. Application: This study may provide the most significant variables for the quantitative evaluation of visual fatigue using HF/LF ratio and ERP latency based human performance and subjective fatigue.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2023년도 춘계학술대회
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• pp.71-71
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• 2023