• 제목/요약/키워드: Physiological parameter

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파킨슨병 환자의 음향 모음 공간 파라미터 비교 (A Comparison of Parameters of Acoustic Vowel Space in Patients with Parkinson's Disease)

  • 강영애;윤규철;이학승;성철재
    • 말소리와 음성과학
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    • 제2권4호
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    • pp.185-192
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    • 2010
  • The acoustic vowel space has been used as an acoustic parameter in dysarthric speech. The aim of this work was to examine mathematical formulae for acoustic vowel space and to apply these to Korean speakers with idiopathic Parkinson's disease(IPD). Five acoustic parameters were chosen from earlier works and one new parameter was proposed, the pentagonal vowel space. The six parameters included triangular vowel space (3 area), irregular quadrilateral vowel space (4 area), irregular pentagonal vowel space (5 area), vowel articulatory index (VAI), formant centralization ratio (FCR) and F2i/F1u ratio (F2 ratio). An experimental group of 32 IPD patients(male:female=16:16) and a control group of twenty healthy people (male:female=8:12) participated in the study and repeated vowels (/a-i-u-e-o/) three times. A correlation analysis was performed among the six parameters, 2-way ANOVA was done with gender and groups as independent factors, and an independent sample t-test was conducted between the male and the female group as post hoc comparison. All parameters were highly correlated with each other and only the FCR showed a high negative correlation with the others. The results of ANOVA showed a significant difference in F2 ratio, 3 area, 4 area and 5 area between gender and in 4 area and 5 area between groups. For the male members of the two groups, significant statistical differences were found in all parameters whereas no such differences were found for the female members. These findings indicated that the vowel space of the female group was wider than the vowel space of the male group. These differences may have been caused by gender-specific speech styles rather than by patho-physiological mechanisms. We also claim that the pentagonal vowel space is better than the other vowel spaces at representing the disordered speech in natural speech situations.

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500명 여성을 대상으로 한 팔강변증에 따른 맥파 특성 연구 (A Study on the Characteristics of Pulse Waves according to Eight Principle Pattern Identification in 500 Women)

  • 이인선;전수형;강창완;김종원
    • 동의생리병리학회지
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    • 제35권6호
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    • pp.274-279
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    • 2021
  • This study was conducted to find objective diagnostic indicators for the Eight Principle Pattern Identification using a pulse wave analyzer. Typology Complexion Pulse and Symptom data from 500 women over the age of 18 were used. Five experts made a diagnosis of Eight Principle Pattern Identification and divided the subjects into 'Yin-Yang', 'Exterior-Interior', 'Cold-Heat', 'Deficiency-Excess' groups. Their pulse waves were measured in the left and right radial arteries, and it was investigated whether there was a significant difference between groups in the pulse wave parameter values. 'Yin' group showed a significantly lower value in the left radial artery for Ener, Emin, EIX, T4T, T4TT parameters and in the Right for T2, T2T, T5. The Vmag, As and Ad parameters were significantly different between the 'Exterior' and 'Interior' groups. 'Heat' group showed a significantly higher value in the right radial artery for RAI/t parameter. 'Deficiency' group showed a significantly higher value in the right radial artery for W, Angl parameters. Through this study, significant pulse wave parameters were found, and they can be used as objective diagnostic indicators for Eight Principle Pattern Identification.

ENERGY UTILIZATION MODELS OF CATTLE GRAZING IN OIL PALM PLANTATIONS II. VALIDATION OF MODELS

  • Dahlan, I.;Mahyuddin, M.D.;Yamada, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제8권1호
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    • pp.67-73
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    • 1995
  • This study showed that models of energy utilization(EU) developed for grazing cattle in oil palm plantations is valid as the simulated results shows an agreement with actual data of calves and cows body weight changes collected from Brahman x Kedah-Kelantan herd on Pengeli Timor Plantation. Simulation runs on EU models demonstrated that the growth pattern of male and female calves and the weight changes of cows are similar and showed slight variation from the actual data but with no significant difference (p > 0.05). Parameter values such as metabolizability (q), dry matter digestibility(DMD) of herbage and voluntary intake of grazing cattle (VIG) and faecal output/body weight ratio (F) of the animals which were collected from the field are essential in bearing the pattern of body weight changes of the calves and cows in relation to increase in time, physiological status and quality of herbage grazed by these animals in the production system. The EU models is suitable for determining the metabolizable energy requirements and to predict the production of grazing cattle according to quality of the feed on offer.

Taguchi's Robust Design Method for Optimization of Lysophosphatidic Acid Production in an Open Reactor System

  • Han, Jeong-Jun;Rhee, Joon-Shick
    • Journal of Microbiology and Biotechnology
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    • 제8권1호
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    • pp.81-88
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    • 1998
  • The determination of appropriate parameters and parameter conditions is very important for the optimization of production of target materials. Taguchi's method has been used widely as the basis for development trials and optimization during industrial process design. Reaction variables which influence product yield are easily determined and their effects are revealed by just a few reactions, negating the need for extensive experimental investigation. There are usually some factors that are responsible for variations in process characteristics, so called noise factors. Controlling noise factors is very costly and difficult or impossible. Taguchi's experimental design method was examined to determine the control factor's level that is less sensitive to the changes in environmental conditions and other noise factors without control of noise factors. In this study, optimization of lipase-catalyzed production of lysophosphatidic acid (LPA) which has various physiological functions was performed by Taguchi's method. We obtained LPA yields ($66.5\%$) with low variance (5.32) at 400 RPM, molar ratio of 40 : 3 (mol) (fatty acid: G-3-P), 48 h, and $50^{\circ}C$. Thus, bioactive LPA with a desired fatty acid moiety could be produced with high yields and low variance despite various environmental noise factors.

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Study on the Characteristic of Eye Movement for Visual Improvement of the Elderly

  • Yu, Mi;Piao, Yong-Jun;Kim, Yong-Yook;Kwon, Tae-Kyu;Hong, Chul-Un;Kim, Nam-Gyun
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2005년도 ICCAS
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    • pp.202-205
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    • 2005
  • The purpose of this work is to identify the characteristic of eye movement for visual training of the elderly. This investigation is to examine the relationship between the head and the eye motor system for the localization of visual target direction in three-dimensional space. All experiments were performed in a soundproof chamber. Twenty-one red LEDs (Light-Emitting Diode, Brightness: 20cd/$m^2$) arrayed in three lines on a half circle-surrounding panel are used. LEDs are horizontally 30 degree apart and vertically 20 degree apart from each other. The condition of stimulation is random and anti-saccade. Physiological parameter such as EOG (Electro-Oculography) was measured by BIOPAC system. We measure the mean latency time, which is the time from the start of visual stimulation to the response of the human body. The result shows that the mean latency time is short in the case of the condition of anti-saccade, the fixed head and a quarter visual stimulation. This finding can be used in developing programs for various visual improvements for the elderly by analyzing the characteristic of eye movement.

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고수온에서 조피볼락(Sebastes schlegeli)의 산소소비 및 혈액성상 변화 (Changes on Hematological Factors and Oxygen Consumption of Korean Rockfish Sebastes schlegeli in High Water Temperature)

  • 도용현;민병화;김영대;박미선
    • 수산해양교육연구
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    • 제28권3호
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    • pp.738-745
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    • 2016
  • Aquaculture production of Korean rockfish Sebastes schlegeli has been continuously increased from 2000s and the fish has become the second most important mariculture fish in Korea. However, there are some environmental problems in aquaculture of Korean rockfish recently. In this regards, stress responses to high water temperature was examined via oxygen consumption, blood physiological parameter and endocrinological method. Oxygen consumption of Korean rockfish had significantly increased with rising water temperature. And oxygen consumption during the light time was no different with the dark time. The levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) showed no difference until $27^{\circ}C$, but it had rapidly increased at $30^{\circ}C$. Moreover high water temperature affected to increase in plasma glucose and cortisol levels.

유발전위를 이용한 뇌의 시감각 및 체성감각 인지영역 추정기술 (Estimating Neuro-Pathway from Visual and Somatosensory Evoked Potential)

  • 배병훈;김동우
    • 대한의용생체공학회:의공학회지
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    • 제15권4호
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    • pp.481-488
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    • 1994
  • 시각 및 손가락의 전기자극에 의해 머리표면에서 발생하는 유발전위를 검출하여 Source Tracing Method를 이용하여 뇌의 시각인지영역 및 손가락 감각인지영역을 추정하였다. 본 과정에서 유발전위 검출방식은 average method를 이용하였고, 흥분뉴런군에 대한 물리적 모델로 Single Current Dipole Model을 이용하고, 머리기하에 대한 3중구각모델을 이용하여 Forward Problem을 풀었다. Inverse Problem은 current dipole의 6개의 parameter에 대한 Least Square Error Method를 이용하여 신견흥분의 위치를 추정하였다. 이러한 결과와 생리학적으로 밝혀진 시각 및 체성감각 신경로와의 비교결과 유사성이 확인되었다.

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퍼지 추론을 이용한 REM의 자동 검출 : 기면증과 정상수면의 REM 분포 연구 (Automatic Detection of Rapid Eye Movement Distribution in Narcoleptic and Normal Sleep Using Fuzzy Logic)

  • 박해정;한주만;최미혜;정도언;박광석
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1998년도 추계학술대회
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    • pp.201-202
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    • 1998
  • In this paper we suggested an automated method for detecting and counting rapid eye movement(REM) using EOG during sleep. This method is formulated by two step fuzzy logic. At first step, the velocity and the distance of single channel eye movement are used for the fuzzy input to get the possibility of being REM at each EOG. At second step, the two possibility values of both EOG from the first step and the correlation coefficient of both eye movements are used for the fuzzy logic input, and the output is the final possibility of being Rapid Eye Movement. We applied this algorithm to the normal and narcoleptic sleep data and compared the difference. We found the possibility that the count of REM can be a parameter that has significant physiological meanings.

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환자모니터링시스템의 개발 : 전체구조 및 기본사양 (Development of a Patient Monitoring System Overall Architecture and Specifications)

  • 우응제;박승훈
    • 대한의용생체공학회:의공학회지
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    • 제18권1호
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    • pp.17-24
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    • 1997
  • We have developed a patient monitoring system including module-based bedside monitors, interbed network, central stations, clinical workstations, and DB servers. A bedside monitor with a color LCD can accommodate up to 3 module cases and 21 different modules. Six different physiological parameters of ECG, respiration, invasive blood pressure, noninvasive blood pressure, body temperature, and arterial pulse oximetry with plethysmoyaph are provided as parameter modules. In a single bedside monitor, modules and a module controller communicate with IMbps data rate through an intrabed network based on RS-485 and HDU protocol. At the same time, it communicates with other bedside monitors and central stations through interbed network based on 1 OMbps Ethernet and TCP/IP protocol. Central stations using 20" color CRT monitors can be connected with many bedside monitors and they display 18 channels of waveforms simultaneously. Clinical workstations are used mainly for the review of patient datE In order to accommodate more advanced data management capabilities such as 24-hour full disclosure, we have developed a relational database server dedicated to the patient monitoring system. Software for bedside monitor, central station, and clinical workstation fully utilizes graphical user interface techniques and all functions are controlled by a rotate/push button on the bedside monitor arid a mouse on the central station and clinical workstation. The entire system satisfies the requirements of AAMI and ANSI standards in terms of electrical safety and performances.nces.

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치료레크리에이션 프로그램이 화상재활환자의 정신건강 상태와 심박동 변이에 미치는 효과 (Effects of a Recreation Therapy Program on Mental Health and Heart Rate Variability in Burn Rehabilitation Patients)

  • 길명숙;이미화;이용미
    • Journal of Korean Biological Nursing Science
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    • 제17권2호
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    • pp.179-187
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    • 2015
  • Purpose: This study was done to evaluate the effects of a recreation therapy program on burn rehabilitation patients to determine if the program is an effective nursing intervention which can affect mental health problems and heart rate variability. Methods: Subjects were 54 hospitalized burn rehabilitation patients (25 in the control group, 29 in the experimental group). The experimental group participated 6 times in a recreation therapy program led by a qualified instructor. Brief symptoms inventory-18 (somatization, anxiety, depression) questionnaire, and heart rate variability were checked before and after the recreation therapy program. Results: The mental health scale showed significant differences in somatization (p<.001), anxiety (p<.001) and depression (p<.001). There was no significant difference in heart rate variability (autonomic activity, autonomic balance, stress resistance, stress parameter and fatigue, mean heart rate, electro-cardiac stability). Conclusion: The findings from this study suggest that a recreation therapy program is an effective nursing intervention to decrease the level of mental health problems of burn rehabilitation patients. However, a subsequent study is needed to develop an intervention program that will induce the effect of physiological parameters like heart rate variability (HRV).