• Title/Summary/Keyword: Physiological Effects

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Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum K10

  • Kim, Seulki;Huang, Eunchong;Park, Soyoung;Holzapfel, Wilhelm;Lim, Sang-Dong
    • Food Science of Animal Resources
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    • v.38 no.3
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    • pp.554-569
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    • 2018
  • This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum K10. The ${\alpha}-amylase$ inhibitory activity, ${\alpha}-glucosidase$ inhibitory activity, and lipase inhibitory activity of L. plantarum K10 was $94.66{\pm}4.34%$, $99.78{\pm}0.12%$, and $87.40{\pm}1.41%$, respectively. Moreover, the strain inhibited the adipocyte differentiation of 3T3-L1 cells ($32.61{\pm}8.32%$) at a concentration of $100{\mu}g/mL$. In order to determine its potential for use as a probiotic, we investigated the physiological characteristics of L. plantarum K10. L. plantarum K10 was resistant to gentamycin, kanamycin, streptomycin, ampicillin, ciprofloxacin, tetracycline, vancomycin, and chloramphenicol. It also showed higher Leucine arylamidase, Valine arylamidase, and ${\beta}-galactosidase$ activities. Moreover, it was comparatively tolerant to bile juice and acid, exhibiting resistance to Escherichia coli, Salmonella Typhimurium, Listeria monocytogenes, and Staphylococcus aureus with rates of 90.71%, 11.86%, 14.19%, and 23.08%, respectively. The strain did not produce biogenic amines and showed higher adhesion to HT-29 cells compared to L. rhamnosus GG. As a result of the animal study, L. plantarum K10 showed significantly lower body weight compared to the high-fat diet group. The administration of L. plantarum K10 resulted in a reduction of subcutaneous fat mass and mesenteric fat mass compared to the high-fat diet (HFD) group. L. plantarum K10 also showed improvement in gut permeability compared to the HFD positive control group. These results demonstrate that L. plantarum K10 has potential as a probiotic with anti-obesity effects.

Effects of Obesity on the Physiological Levels of Adiponectin, Leptin and Diagnostic Indices of Metabolic Syndrome in Male Workers (남성 근로자의 비만이 adiponectin과 leptin의 생리적 농도와 대사증후군 진단지표에 미치는 영향)

  • Heo, Kyung-Hwa;Won, Yong-Lim;Ko, Kyung-Sun;Kim, Ki-Woong
    • Korean Journal of Occupational Health Nursing
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    • v.18 no.1
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    • pp.44-54
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    • 2009
  • Purpose: The aim of this study was to examine the effects of obesity on the physiological levels of adiponectin, leptin and components of metabolic syndrome (MS) in male workers, aged 30-40 years. Methods: Body mass index (BMI) was measured with Anthropometric equipment. Blood pressure and serum parameters were measured with an automatic digital sphygmomanometer and autochemical analyzer, respectively. Adiponectin and leptin were analysed by ELISA kits and MS was defined based on the NCEP-ATP III. Results: Body fat mass of waist and hip, systolic and diastolic blood pressure were significantly higher, as expected, in the BMI>25kg/$m^2$ in comparison with the $BMI{\leq}25kg/m^2$. While fasting glucose, insulin, HOMA-IR and leptin in the BMI>25kg/$m^2$ were also significantly higher compared with $BMI{\leq}25kg/m^2$, HDL-cholesterol and adiponectin were significantly higher in $BMI{\leq}25kg/m^2$. On multiple logistic regression analysis for the components of MS, exercise, adiponectin and leptin were an only independent factor for MS in non-obese male workers($BMI{\leq}25kg/m^2$) after adjustment for age, cigarette smoking and drinking habits. Conclusion: These results suggested that the obesity in men was associated with physiological levels of adiponectin and leptin contributing to feedback control of MS and that dysfunction and/or declination in feedback control system associated with changes in physiological levels of neurptrophics: adiponectin and leptin might ultimately induce MS.

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Physiological and psychological effects of nature-based outdoor activities on firefighters in South Korea

  • Sang-Eun Lee;Heon-Gyo Kwon;Jisu Hwang;Hyelim Lee;Dawou Joung;Bum-Jin Park
    • Korean Journal of Agricultural Science
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    • v.51 no.1
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    • pp.9-23
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    • 2024
  • This study investigates the physiological and psychological effects of a nature-based outdoor activity program in an environment reflecting the characteristics of forest and coastal areas on 30 firefighters (average age: 40.4 ± 9.8 years) who are frequently exposed to dangerous situations. Blood pressure, pulse pressure, and heart rate variability were used as physiological measurement indicators, and the Korean versions of PANAS (positive affect and negative affect schedule), WEMWBS (Warwick-Edinburgh mental well-being scale), and PRS (perceived restorativeness scale) were used as psychological measurement indicators. For four days and three nights, the participants experienced programs at Hallyeohaesang Nature Center and the surrounding mountains, seas, and islands, utilizing forest resources such as trekking on forest trails, walking barefoot, taking aromatic footbaths, meditating in forest oxygen domes, and lying on relaxation chairs, and programs utilizing marine resources such as taking a boat to an island, walking on forest trails with seascape views, and sailing on a yacht. Participants' systolic blood pressure and pulse pressure decreased, and participants' positive emotions increased and negative emotions decreased after the program. There was a statistically significant increase in mental well-being and perceived restorative environment. Through this study, it was found that nature-based outdoor activity programs based on forest and marine resources are effective in physiological and psychological stability of firefighters. It is hoped that the results of this study will be applied to other high-risk workers for PTSD, who have high stress levels, by combining forest healing and marine healing, and expanding the scope and diversity of programs in more diverse environments and conditions.

Correlation between Consonants' Place and Vowel Duration in English and Korean (자음의 조음 위치와 인접 모음 길이의 상관성에 관한 연구: 영어와 한국어의 경우)

  • Oh, Eun-Jin
    • Speech Sciences
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    • v.9 no.3
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    • pp.201-210
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    • 2002
  • This paper explores whether there is correlation between consonants' place and duration of adjacent vowels in English and Korean. The results showed that in English the vowels preceding alveolar stops were in general longer than the vowels before bilabial or velar stops. Consonants appeared to have their inherent length due to their place and to exhibit some compensatory effects on the duration of preceding vowels. This effect can be explained in a physiological term that the tongue tip is the organ which might be more agile in articulatory movement than the tongue body for the velars or the lower lip (and the jaw) for the bilabials is and the shorter production time of the alveolars caused the lengthening of the adjacent vowels. However, this physiological account did not hold in the case of Korean, which exhibited less consistent patterns across speakers for the consonants' place and the vowel duration. The segmental duration seemed to be timed quite consistently within a language but the pattern was not universal across languages.

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Suppression of nitric oxide (NO) production by traditional medicine

  • Lee, Jin Soo;Jeong, Hyun-Ja
    • CELLMED
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    • v.8 no.2
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    • pp.8.1-8.5
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    • 2018
  • Nitric oxide (NO) is a small diffusible molecule which plays an important role in various physiological activities. NO is a notable molecule, functioning as a cytotoxic agent and cellular messenger. There has been considerable interest in NO production by activated macrophages because this gaseous metabolite plays a fundamental role in the cytotoxic and cytostatic effects of macrophages towards invasive micro-organisms and tumour cells. No is a bioactive free radical that has been implicated in many physiological functions, plays a critical role during inflammation and therefore constitutes a potential target for developing therapeutics for inflammatory diseases. The use of medicinal plants by the population has been an important alternative the resource in the treatment of various diseases. Its growing acceptance in the medical community has been due to the fact that several plants with biological activities have been scientifically investigated and their efficacy and safety have been proven. In this review, discussed suppressive effects of No production by traditional medicines in RAW 264.7 and THP-1 macrophages.

Isolation Identification and Physiological Characteristics of Some Sulfur-Reducing Microbes (수종 유황환원균주의 분리, 동정 및 그의 생리적 특성에 대하여)

  • 이민재;오명수
    • Korean Journal of Microbiology
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    • v.10 no.4
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    • pp.175-190
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    • 1972
  • This work was designed to illustrate physiological effects on the elimination of sulfur and its compounds in petroleum using sulfur-reducing bacteria. Deulfurizing bacteria were collected from sewage and soil at several areas in Soul and Ulsan, Korea. Seven supecies of sulfur-reducing microbes isolated were identified as : Pseudomonas marginata, Ps.effusa, Ps. putrefaciens, Ps.pseudcmcnelli, Ps. xanthochlora, Ps.bowlesiae, and Ps.aeruginosa. And some experiments were performed to define the growing characteristics of the Pseudomonads and the results obtained are as follows : 1) Shaking culture method was more effective for the growth of the cells than stagnant culture. 2) Beef peptone medium was better for the growth than other media. 3) Cuprous chloride of 50 ppm and cupper sulfate of 300 ppm treated, respectively, in the medium were effective for the growth. 4) Benzene of toluene of 5,000 ppm and petroleum ether of 50,000 ppm did not show remarkable inhibitory effects on the growth.

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The Effects of Waste Leachate on the Eco-Physiological Characteristics of Populus euramericana

  • Woo, Su-Young
    • The Korean Journal of Ecology
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    • v.22 no.6
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    • pp.343-348
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    • 1999
  • Populus euramericana has been identified as a possible species for use for phytoremediation of landfills. To identify the effects of waste leachate on the growth and physiological characteristics of Populus euramericana. four different treatments were applied to Populus euramericana seedlings: leachate solution (100% leachate). 25% dilution (75% leachate: 25% water. v/v), 50% dilution (50% leachate: 50% water. v/v) and control (100% tab water) were applied to Populus euramericana. Treatment with waste leachate significantly stimulated Populus euramericana height. diameter at root collar and biomass production relative to the water control. Chlorophyll contents. photosynthesis and transpiration of leachate irrigated-trees were significantly higher than those of water control. These results suggested that poplar could be a suitable species for phytoremediation in landfills because these species showed good growth performance and were capable of taking up waste leachate.

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Current use of growth hormone in children (성장호르몬 치료의 최신 지견)

  • Shin, Choong Ho
    • Clinical and Experimental Pediatrics
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    • v.49 no.7
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    • pp.703-709
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    • 2006
  • Since the advent of growth hormone(GH), children with a wide variety of growth disorders have received GH treatment. In GH deficiency(GHD), Turner syndrome, chronic renal failure, children born small for gestational age, Prader-Willi syndrome, and idiopathic short stature, the therapeutic effects and safety profile of GH are reviewed. GH therapy has been clearly shown to improve height velocity and final adult height in a variety of pediatric conditions in which growth is compromised irrespective of GHD. Early initiation and individualization of GH treatment has the potential to normalize childhood growth. The supra-physiological doses of GH have been shown to increase height velocity during childhood and final height in non-GHD conditions. Adverse events during GH therapy are uncommon and often not drug related. However continued surveillance into adult life is crucial, especially in children receiving supra-physiological doses or whose underlying condition increases their risk of adverse effects.

Antioxidant capacity of phytochemicals and their potential effects on oxidative status in animals - A review

  • Lee, M.T.;Lin, W.C.;Yu, B.;Lee, T.T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.3
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    • pp.299-308
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    • 2017
  • Oxidative stress suppresses animal health, performance, and production, subsequently impacting economic feasibility; hence, maintaining and improving oxidative status especially through natural nutrition strategy are essential for normal physiological process in animals. Phytochemicals are naturally occurring antioxidants that could be considered as one of the most promising materials used in animal diets in various forms. In this review, their antioxidant effects on animals are discussed as reflected by improved apparent performance, productivity, and the internal physiological changes. Moreover, the antioxidant actions toward animals further describe a molecular basis to elucidate their underlying mechanisms targeting signal transduction pathways, especially through the antioxidant response element/nuclear factor (erythroid-derived 2)-like 2 transcription system.

Inhibitory effect of chitosan oligosaccharides on the growth of tumor cells

  • Kim, Se-Kwon;Nam, Mi-Young;Nam, Kyung-Soo
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2000.05a
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    • pp.416-417
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    • 2000
  • Chitin, a poly $\beta$-(1longrightarrow14)-N-acetyl-D-glucosamine, is best known as a cell wall component of fungi and as a skeletal materials of invertebrates. Chitosan is derived from chitin by deacetylation in the presence of alkali. Chitosan has been developed as new physiological materials since it possesses antibacterial activity, hypocholesterolemic activity and antihypertensive action. However, the actions of chitosan in vivo still remain ambiguous as the physiological functional properties because most animal intestines, especially the human gastrointestinal tract, do not possess enzyme such as chitosanase which directly degrade the $\beta$-glucosidic linkage in chitosan, and consequently the unbroken polymers may be poorly absorbed into the human intestine. Therefore, recent studies as chitosan have attracted interest for chitosan oligosaccharides, because the oligosaccharides process not only water-soluble property but also versatile functional properties such as antitumor activity, immune-enhancing effects, enhancement of protective effects against infection with some pathogens in mice and antimicrobial activity (Kingsnorth et al., 1983, Mori et al., 1997). (omitted)

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