• Journal of Preventive Medicine and Public Health
• /
• v.35 no.4
• /
• pp.282-286
• /
• 2002

Objectives : The level of 4-hydroxyproline (4-Hyp) in human urine was measured using high performance liquid chromatography (HPLC) with a fluorescence detector. This method is useful for medical examinations and investigating the radicals induced by physical, chemical, mental stresses. This method is superior to many published several methods in terms of its low cost and ability to analyze many samples. Methods : The urine from workers in a tire manufacturing company (22 male pre- and post-shift workers) and 18 office-workers as controls were analyzed. Data concerning age, the cumulative drinking amount and the cumulative smoking amount was collected with a questionnaire. The optimum applied amount of dansyl-Cl, the optimum reaction temperature and time, the recoveries and the optimum pH of the eluent and buffer were determined.4-Hyp from human urine was derivatized with dansyl-Cl (dimethylamino-naphthalene-1-sulfonyl chloride) after removing the a-amino acid by a treatment with phthalic dicarboxaldehyde (OPA) and cleaned with Bond Elut C18 column. The 4-Hyp derivatives were separated on a reversed phase column by gradient elution with a phosphate buffer (5 mmol, pH 8.0) and acetonitrile, and detected by fluorescence measurements at 340 nm (excitation) and 538 nm (emission). Results : The detection limit for the urinary free 4-Hyp was $0.364{\mu}mol/l$. The recovery rate of 4-Hyp was 99.7%, and the effective pH of the phosphate buffer and borate buffer were 3.0 and 8.0, respectively. From statistical analysis, age, drinking and smoking did not affect the urinary free 4-Hyp in both the controls and workers. The range of urinary 4-Hyp in the controls, pre-shift, and post-shift workers were 0.33-16.44, N.D-49.06, and $0.32-56.27{\mu}mol/l$. From the pared-sample t-test, the urinary 4-Hyp levels in post-shift workers ($11.82{\pm}6.73\;nmmol/mg\;Cre$) were 2-fold higher than in pre-shift workers ($5.36{\pm}5.53\;nmol;/mg\;Cre$) and controls ($4.91{\pm}4.89\;nmol;/mg\;Cre$). Conclusions : This method was developed with high sensitivity, accuracy, and precision. The present method was effectively applied to analyze the urinary free 4-Hyp in both controls and workers.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.10
• /
• pp.562-568
• /
• 2016

This study to investigated the therapeutic effect of robot-assisted rehabilitation (Lokomat) with virtual reality (VR) on Pusher syndrome (PS) after stroke. A total of 10 patients presented with PS after stroke were recruited. The participants were divided into two groups: Lokomat (n=5) and control groups (n=5). Lokomat and conventional physical therapy (CPT) were performed together in the experimental group, and the patients in the control group were treated with CPT only twice a day. One session of intervention was carried out for 30 minutes five times per week for 4 weeks. Scale for contraversive pushing (SCP), Berg balance scale (BBS), falling index (FI), and Timed up and go test (TUG) were measured before and after the intervention. The Lokomat group produced significantly better outcomes in SCP (p=0.046), BBS (p=0.046), FI (p=0.038), and TUG (p=0.038) compared with the control group after 4 weeks of intervention. In addition, there were significant correlations between SCP and BBS (p=0.024), FI (p=0.039), and TUG (p=0.030). In conclusion, Lokomat with VR more effectively aided recovery from PS after stroke, and restoration of PS symptoms was related with improvement of balance and gait function.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.12 no.3
• /
• pp.101-115
• /
• 2009

The prompt recovery of housing market in Korea became the national task, for which tools that can analyze the influence that changing situation of housing market and new policy may have on the housing market needs to be developed. Thus, this research intends to develop Multi-Agent Housing Market Model and simulation system in Jinju City as a study area. Analyzing the local housing market of Jinju City, then multi-agent model of housing market that consolidates 3 sub-models, house choice model, hedonic model of house price and location choice model is developed. Moreover in order to develop simulation system the model is programmed in the virtual space of which the size is $150{\times}100$ cell including physical shape of city such as road, urban facilities, land use, etc. With the system, simulations are performed to confirm the impact of urban development on the pattern of residential location. As a result, it is found that the residential location can not be easily induced when only road, commercial and convenient facilities are supplied. However, it is also found that since supplying green results in very many residences, arrangement of infrastructure and environmental factor should be considered at the same time for urban development. As conclusion, it is confirmed that the model and simulation system developed in this research smoothly works to be utilized for the analysis of diverse policy experiment and housing market.

• Geophysics and Geophysical Exploration
• /
• v.23 no.1
• /
• pp.38-49
• /
• 2020

Full-waveform inversion (FWI) is an optimization process of fitting observed and modeled data to reconstruct high-resolution subsurface physical models. In acoustic FWI (AFWI), pressure data acquired using a marine streamer has mainly been used to reconstruct the subsurface P-wave velocity models. With recent advances in marine seismic-acquisition techniques, acquiring multi-component data in marine environments have become increasingly common. Thus, AFWI strategies must be developed to effectively use marine multi-component data. Herein, we proposed an AFWI strategy using horizontal and vertical particle-acceleration data. By analyzing the modeled acoustic data and conducting sensitivity kernel analysis, we first investigated the characteristics of each data component using AFWI. Common-shot gathers show that direct, diving, and reflection waves appearing in the pressure data are separated in each component of the particle-acceleration data. Sensitivity kernel analyses show that the horizontal particle-acceleration wavefields typically contribute to the recovery of the long-wavelength structures in the shallow part of the model, and the vertical particle-acceleration wavefields are generally required to reconstruct long- and short-wavelength structures in the deep parts and over the whole area of a given model. Finally, we present a sequential-inversion strategy for using the particle-acceleration wavefields. We believe that this approach can be used to reconstruct a reasonable P-wave velocity model, even when the pressure data is not available.

• Journal of Digital Convergence
• /
• v.19 no.10
• /
• pp.349-355
• /
• 2021

This study applied aquatic and land-based exercises to breast cancer patients for comparative analysis and elucidation of their effects on the rehabilitation of cancer patients. Participants included 40 breast cancer patients who were divided into two groups: 20 participants in the experimental group using aquatic exercise and 20 participants in the control group using land-based exercise. After the addition of aquatic or land-based exercises five times per week for eight weeks, differences in each group's shoulder and pulmonary functions as well as their quality of life were compared and analyzed. The results showed a statistically significant difference (p<.001) for shoulder dysfunction, with the experimental group showing a greater improvement than the comparison group. Statistically significant differences (p<.05 and p<.001, respectively) were also observed for forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), with the experimental group showing greater improvements. Finally, a statistically significant difference (p<.001) was observed for change in the quality of life, with greater improvements in the experimental group than in the control group. The results of further research in this field are expected to indicate the most efficient method for the recovery and management of physical, psychological, and social health impacts of breast cancer on patients. Furthermore, the research aims to provide fundamental resources for breast cancer rehabilitation in South Korea by conducting studies on patients with lung cancer or colorectal cancer and the application of various aquatic exercise methods.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.25 no.4
• /
• pp.28-36
• /
• 2021

It is known that buried rebars inside concrete structures are protected from corrosion due to passive layer. It is very important to delay the timing of corrosion or evaluate a detection of corrosion initiation for the purpose of cost-beneficiary service life of a structure. In this study, corrosion monitoring was performed on concrete specimens considering 3 levels of cover depth(60 mm, 45 mm, and 30 mm), W/C(water to cement) ratio(40.0%, 50.0%, and 60.0%) and chloride concentration(0.0%, 3.5%, and 7.0%). OCP(Open Circuit Potential) was measured using agar-based socket type sensors. The OCP measurement showed the consistent behavior where the potential was reduced in wet conditions and it was partially recovered in dry conditions. In the case of 30 mm of cover depth for most W/C ratio cases, the lowest OCP value was measured and rapid OCP recovery was evaluated in increasing cover depth from 30 mm to 45 mm, since cover depth was an effective protection against chloride ion ingress. As the chloride concentration increased, the effect on the cover depth tended to be more dominant than the that of W/C ratio. After additional monitoring and physical evaluation of chloride concentration after specimen dismantling, the proposed system can be improved with increasing reliability of the corrosion monitoring.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.2
• /
• pp.694-703
• /
• 2019

This study was to investigate the effect of therapeutic exercise with electrical stimulation on knee joint pain, range of motion and muscle strength in patients who underwent anterior cruciate ligament reconstruction. The subjects of this study were recruited who diagnosed with anterior cruciate ligament rupture and undergoing anterior cruciate ligament reconstruction, total of 20 patients were randomly divided to the 10 control groups and 10 experimental groups. The therapeutic exercise was carried out for 3 weeks with three exercises made by referring to the previous study. The measurement tools used were knee joint pain measurements were made using the visual analogue scale, range of motion was measured using a goniometer, and the muscle strength was measured using a handheld dynamometer. In the statistical analysis, to compare about pre and post test the difference in each same groups was accomplished by using the paired t-test, and compare the difference between the different each groups was accomplished by using the independent t-test. The results of the study showed that the experimental group showed significantly enhanced results than the control group(p<.05). Based on these results, it is concluded that it is effective for the recovery of the patient if the therapeutic exercise with electrical stimulation in parallel with knee joint therapy are performed for the patients with anterior cruciate ligament reconstruction.

• The Korean Journal of Archival Studies
• /
• no.14
• /
• pp.91-117
• /
• 2006

Electronic Records need to be appraised the authenticity as well as the value itself. There has been various kinds of discussion about how records to be appraised the value of themselves, but there's little argument about how electronic records to be appraised the authenticity of themselves. Therefore this article is modeling some specific authenticity appraisal methods and showing each stages those methods should or may be applied. At the Ingest stage, integrity verification right after records creation in the organization which produced the records, quality and integrity verification about the transferred in the organization which received the records and integrity check between SIP and AIP in the organization which received and preserved the records are essential. At the Preservation stage, integrity check between same AIPs stored in different medium separately and validation of records where or not damaged and recovery damaged records are needed. At the various Processing stages, suitability evaluation after changing the record's management control meta data and changing the record's classification, integrity check after records migration and periodical validation and integrity verification about DIPs are required. For those activities, the appraisal methods including integrity verification, content consistency check, suitability evaluation about record's meta data, feasibility check of unauthorized update and physical status validation should be applied to the electronic records management process.

• The Journal of the Convergence on Culture Technology
• /
• v.5 no.3
• /
• pp.359-367
• /
• 2019

The purpose of this study was to investigate the effects of ingestion of rabies and ginseng fruit extracts on alcohol hangover, liver damage protection, fatigue recovery, and physical strength improvement. A total of 64 volunteers aged over 20 were participated in this study and the randomized and repeated measures design method was used to divide a group of participants with a random assignment. All participants were divided into 4 groups (n=16) treated with hoveni dulcis thunb extract + ginseng berry extract (ARI 1000), hoveni dulcis thunb extract, ginseng berry extract, and placebo. As a result of respiratory alcohol concentration change, the group treated with ARI 1000 was significantly lower than the group treated with hoveni dulcis thunb extract, ginseng berry extract, and placebo in 1 hour of drinking, and significantly lower than the placebo group in 2 hours and 3 hours of drinking (p<0.05). After 2 and 3 hours of alcohol consumption, blood alcohol concentration of the group treated with rabies ARI 1000 was significantly lower than those of the other 3 groups (p <0.05). In conclusion, ingestion of ARI 1000 before drinking may significantly reduce the respiratory and blood alcohol concentrations, which may induce an effect on the hangover effect.

• Asian-Australasian Journal of Animal Sciences
• /
• v.32 no.8
• /
• pp.1145-1152
• /
• 2019

Objective: Mulberry (Morus alba L.) is a cultivated shrub grown widely in the sub-tropical and tropical areas. It has been shown that mulberry leaf contains high levels of protein while having polyphenols as phytonutrients. Therefore, it is important to conduct an experiment to assess potential toxic level from mulberry on behavior, blood hematological and coagulation parameter using Sprague-Dawley (SD) rats. Methods: Both male and female SD rats were given an intragastric administration of respective treatments of mulberry leaf intakes (control, low and high levels). Parameters of feed intake, hematological and coagulation of blood parameters, as well as liveweight changes were taken during the 7 d of adaptation, 28 d of treatment exposure, and 14 d of recovery periods, respectively. All treatment data were statistically analyzed using analysis of variance of SPSS17.0 for Windows Statistical Software following the Randomized complete block design with sex as a block. Results: Most of the parameters of the physical symptoms of the SD rats, were not significantly different (p>0.05) when compared with that of the control group. Those which remain unchanged in each dose group were, body weight (BW) gain, feed intake, the hematology and coagulation indexes. Although, there were a few individual indicators that were abnormal, but the overall physiological appearance of the rats were normal. Conclusion: Results under this experiment revealed that most hematological and coagulation parameters of the SD rats in both male and female were normal, although the weight gain of female rats in high-dose group was significantly reduced than those of the male rats. Under this study, the use of mulberry leaf up to 2 g/kg BW did not result in abnormal phenomenon in the SD rats. These findings would offer useful information for further in vivo feeding trials in animals to extensively use of mulberry leaf to improve animal production, particularly in P.R. China.