• Title/Summary/Keyword: Physical presence

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Secondary Fermented Extract of Chaga-Cheonggukjang Attenuates the Effects of Obesity and Suppresses Inflammatory Response in the Liver and Spleen of High-Fat Diet-Induced Obese Mice

  • Na, Ha Gyoon;Park, Yuna;Kim, Min-Ah;Lee, Jin Woo;So, Gyeongseop;Kim, Sung Hyeok;Jang, Ki-Hyo;Kim, Mi-Ja;Namkoong, Seung;Koo, Hyun Jung;Lee, Sung Ryul;Sohn, Eun-Hwa
    • Journal of Microbiology and Biotechnology
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    • v.29 no.5
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    • pp.739-748
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    • 2019
  • Cheonggukjang and chaga mushrooms have numerous health benefits, and have been used in alternative medicine. Therefore, a powder mixture of 98: Cheonggukjang and 2: Chaga extracts was fermented with Lactobacillus acidophilus KCTC3925 (FCC) and its anti-obesity effects in high-fat diet (HFD)-induced obese mice were determined. Five-week-old male ICR mice were fed a normal diet or HFD in the presence or absence of 3% and 5% FCC by weight (n = 10 per group). After 12 weeks, the mice were sacrificed, and the serum and tissue samples were collected for analysis. Body weight and epididymal fat pad weight were significantly lowered in the 3% and 5% FCC groups compared with those in the HFD control group (p < 0.01). FCC supplementation suppressed serum triglyceride and increased serum HDL-C levels (p < 0.01). Serum GOT, GPT, and leptin levels, hepatic COX-2 mRNA expression, and splenic COX-2 and IL-4 mRNA expression were significantly higher in the HFD groups than in the control group (p > 0.05); however, except for splenic IL-4 levels, the increases were significantly attenuated by FCC supplementation. Expression of ICAM-1, an aortic inflammatory marker, was significantly increased in the HFD group; this effect was suppressed in the 3% FCC group (p < 0.01) but not in the 5% FCC group. FCC suppressed the body weight and epididymal fat pad weight gain, as well as inflammatory responses in the liver and spleen of HFD-fed mice. Thus, FCC supplementation will be beneficial for the treatment of obesity-related effects.

A Study on the Characteristics of Clinker and Cement as Chlorine Content (염소 함량에 따른 클링커 및 시멘트의 물성에 관한 연구)

  • Lee, Young-Jun;Kim, Nam-Il;Cho, Jeong-Hoon;Seo, Sung-Kwan;Chu, Yong-Sik
    • Resources Recycling
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    • v.30 no.5
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    • pp.10-16
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    • 2021
  • In this study, a clinker was prepared using raw materials with CaCl2. The characteristics of the chlorine-added clinker and cement were analyzed. The clinker modulus were set to Lime Saturation Factor (LSF) 92, Silica modulus (SM) 2.5, and Iron Modulus (IM) 1.5. The physical properties of cement using the chlorine-containing clinker were characterized. As the chlorine content increased, the free-CaO content in the clinker decreased, and that in the 2000 ppm clinker was reduced by approximately 40% compared to that in the 0 ppm clinker. There was an increase in the amount of chlormayenite, with a content of up to 3.4% present in the 2000 ppm clinker. The amounts of alite and belite also slightly increased. The compressive strength of mortar at 3 days and 7 days increased as the chlorine content increased. This trend was presumed to arise from the effect of hydration, which was promoted by the presence of chlorine. The compressive strength of 1000 ppm mortar increased by approximately 20% compared to that of 0 ppm mortar.

A Characteristic Analysis of Glass Beads in Geumgwan Gaya, Korea (I) (금관가야 유리구슬의 특성 분석 (I))

  • Kim, Eun A;Lee, Je Hyun;Kim, Gyu Ho
    • Journal of Conservation Science
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    • v.37 no.3
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    • pp.232-244
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    • 2021
  • This study examined the physical attributes and heat treatment characteristics of glass beads excavated from the Gimhae area, which is the location of Geumgwan Gaya. This enabled classification of surface characteristics of the beads based on the investigation of the color, size, and shape. The glass beads were classified into eight color systems, with purplish-blue beads as the representative color. Bead size was categorized into three types depending on the outer diameter and how it increased over time. Bead shapes were categorized as round, tubular, or doughnut-shaped based on the inner diameter and length, with round being the typical shape. According to the degree of heat treatment, there are three types of cross-section for glass beads that are manufactured by the drawing technique, most of which are the HT-III type. In addition, it is estimated that the heat treatment technology has more considerable effects than other methods. Through non-destructive analysis, the chemical composition was obtained and categorized as flux, stabilizer, and colorant. Analysis confirmed the presence of 63 and 9 pieces in the potash and soda glass groups, respectively. Overall findings from the study highlighted a correlation between the chemical composition and the external factors such as color, size, shape, and manufacturing technology of glass beads recovered from Geumgwan Gaya, revealing characteristics related to that time and region.

Fabrication of Chitosan Nanoparticles with Lactococcus lactis for the Removal of Phthalate Endocrine Hormone (Phthalate계 환경호르몬 제거를 위한 Lactococcus lactis를 함유한 Chitosan Nanoparticles의 제조)

  • Yoon, Hee-Soo;Kang, Ik-Joong
    • Korean Chemical Engineering Research
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    • v.59 no.1
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    • pp.21-34
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    • 2021
  • Chitosan nanoparticles (CNPs) and Lactococcus lactis (L. lac.) were used as adsorbents to evaluate the adsorption performance of endocrine hormones, which are phthalates, in the healthy food packages. CNPs were produced through the cross bond with tripolyphosphate (TPP), and L. lac.-CNPs were prepared through the introduction of L. lac. during the preparation. The various functional groups of all adsorbents were identified using Fourier transform infrared spectroscopy (FTIR). Adsorption isotherm and adsorption kinetic confirmed the adsorption behavior and mechanism of CNPs, L. lac. and L. lac.-CNPs. The adsorption behavior of DBP and DEP for all particles was more suitable for the Freundlich adsorption isotherm model than for the Langmuir adsorption isotherm model, which means that the surface of the particles is heterogeneous. The adsorption mechanism was more suitable for the Pseudo-2nd-order model than for the Pseudo-1st-order model. This means that due to the presence of various functional groups on the particle surface, the adsorption of DBP and DEP is dominated by chemical adsorption such as electrostatic attraction and hydrogen bonding rather than physical adsorption. Finally, it was confirmed that the preparation of CNPs and L. lac.-CNPs can be performed easily and quickly, and it could be used as a cheaper adsorbent that can effectively remove phthalates.

Calculation (Computation) of Habitat Suitability Index for Swimming Fish Species Living in Miho Stream in Geum River Water System (금강수계 미호천에 서식하고 있는 유영성 어종의 서식지적합도지수 산정)

  • Hur, Jun Wook;Kim, Kyung Hoon;Lee, Jong Jin
    • Ecology and Resilient Infrastructure
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    • v.8 no.1
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    • pp.9-21
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    • 2021
  • In this study, fish and flow surveys were conducted at 12 survey points to calculate the fish habitat suitability index of Miho Stream in the Geum River Water System. The field surveys were conducted four times from September 2019 to May 2020. The results show the presence of 8 families, 37 species, and 5,754 individuals. The number of water purification species that preferred waters with a low flow rate was the highest. The habitat suitability index was calculated according to the Washington Department of Fish and Wildlife method based on the populations collected at various water depths and flow rate sections and the flow rate survey results. For the dominant species, Zacco platypus and swimming species, the results were compared by calculating at Gasan Bridge and Palgye Bridge at the upper stream. The single species showed no significant difference between the upstream and downstream at water depths of 0.1 - 0.5 m and flow rates of 0.2 - 0.5 m/s. The species swimming ability was similarly calculated at water depths of 0.2 - 0.5 m and flow rates of 0.2 - 0.5 m/s. The dominant species, Pyramid, had a wide range of physical habitats. The habitat suitability index between the swimming species was similarly calculated. These results can be effectively used as basic data for calculating the environmental ecological flow rate and establishing a river restoration plan of the Miho Stream.

The analysis of Factors associated with the Health Examination expenditure in a General Hospital based on the cased (일개 종합병원 종합(민간)검진 비용 영향요인 분석)

  • Lim, Ji Hyun;Suh, Won Sik
    • Korea Journal of Hospital Management
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    • v.25 no.4
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    • pp.76-93
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    • 2020
  • Purpose: In this study, the general characteristics of subjects who spent more than a certain amount of cost for general medical examination at the general hospital health promotion center, and the characteristics of disease, family history, and lifestyle (smoking, alcohol, physical activity, oral care) significantly differed in cost expenditure. We intend to provide basic data for establishing an appropriate marketing strategy for comprehensive examination. Method: It was conducted for users who received comprehensive checkups at a health promotion center at a general hospital in Seoul. The research data collection period is for 979 people who performed comprehensive examinations from January 2019 to December 2020. In order to carry out a comprehensive examination, a questionnaire before the examination was distributed to the subjects who visited the hospital to prepare, and the investigation was conducted in a way that the subjects of the investigation directly filled in. Results: There was a significant influence on the difference in expenditure for comprehensive examination according to the gender, age, and type of health insurance of the subject. In addition, there were significant differences in expenditure according to the presence or absence of disease and the type of family history. Weight loss, smoking history, smoking period, smoking frequency, drinking history, and drinking frequency all had significant effects on cost expenditure. Also, strength training and oral treatment management showed a significant effect on the cost of comprehensive examination. The number of flossing and interdental brushing was also found to have a significant effect. According to the results of multiple regression analysis, disease history (t=2.683, p<.01) and mean smoking frequency (t=4.315, p<.001) appeared to have the most significant effect on expenditure statistically. In other words, when the subject has a history of disease and when the average number of smoking is large, it means that the comprehensive examination cost is remarkably large. Conclusion: By using these contents, hospitals can further refine the marketing of the examination center. In addition, a more convenient and specialized process should be used by patients by linking the general medical department and the examination center well. In terms of management of operating medical institutions, this can be expected to create patients and increase profits.

Adsorption of Dyes with Different Functional Group by Activated Carbon: Parameters and Competitive Adsorption (활성탄에 의한 작용기가 다른 염료의 흡착: 파라미터 및 경쟁 흡착)

  • Lee, Jong Jib
    • Applied Chemistry for Engineering
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    • v.33 no.2
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    • pp.151-158
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    • 2022
  • In this paper, parameter characteristics such as pH effect, isotherm, kinetic and thermodynamic parameters and competitive adsorption of dyes including malachite green (MG), direct red 81 (DR 81) and thioflavin S (TS), which have different functional groups, being adsorbed onto activated carbon were investigated. Langmuir, Freundlich and Temkin isotherm models were employed to find the adsorption mechanism. Effectiveness of adsorption treatment of three dyes by activated carbon were confirmed by the Langmuir dimensionless separation factor. The mechanism was found to be a physical adsorption which can be verified through the adsorption heat calculated by Temkin equation. The adsorption kinetics followed the pseudo second order and the rate limiting step was intra-particle diffusion. The positive enthalpy and entropy changes showed an endothermic reaction and increased disorder via adsorption at the S-L interface, respectively. For each dye molecule, negative Gibbs free energy increased with the temperature, which means that the process is spontaneous. In the binary component system, it was found that the same functional groups of the dye could interfere with the mutual adsorption, and different functional groups did not significantly affect the adsorption. In the ternary component system, the adsorption for MG lowered a bit, likely to be disturbed by the other dyes meanwhile DR 81 and TS were to be positively affected by the presence of MG, thus resulting in much higher adsorption.

Evaluation of 3D Printing Filaments for Radiation Shielding using High Density Polyethylene and Bismuth (고밀도 폴리에틸렌과 비스무트를 이용한 3D 프린팅용 방사선 복합필라멘트 개발 및 차폐능력 평가)

  • Park, Ki-Seok;Kim, Dong-Hyun
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.233-240
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    • 2022
  • Research on the presence or absence of radiation shielding for FDM-type filaments has recently begun to be studied, but filaments with shielding capabilities are not sold in Korea, and not studies yet. Therefore, in this research, we will use HDPE (High Density Polyethylene) as a base material, select bismuth as a reinforcing material to manufacture a composite filament, evaluate the shielding ability, and provide basic data for the development of a radiation shielding composite material using 3D printing.A filament is produced by mixing Bismuth with an effective atomic number 83 with HDPE of PE series and adjusting the content of Bismuth to 20% wt, 30% wt, 40% wt. Compounded filaments were evaluated for their physical properties and shielding capabilities by ASTM evaluation methods. As the bismuth content increases, the density, weight, and tensile strength increase, and the shielding capacity is confirmed to be excellent. As a result of the radiation shielding capacity evaluation, it was confirmed that HDPE (80%) + Bi (20%) showed a shielding rate of 82% at 60 kV and a shielding rate of up to 94% or more at 40% bismuth content. In this study, we confirmed that it was possible to produce a radiation shield that is lighter than the metal particle-containing filaments. Furthermore, that have been shield radiation by using HDPE + Bi filaments, and radiation in the medical and radiation industries. The possibility of using it as a shielding complex was confirmed.

Experiences of Ageism and "Self-Ageism" (노인차별 경험과 자기연령주의(self-ageism))

  • Kim, Juhyun;Oh, Hyein;Ju, Kyonghee
    • 한국노년학
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    • v.40 no.4
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    • pp.659-689
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    • 2020
  • This study focuses on the process of internalizing the perception of negative discrimination among elderly people who have experienced age discrimination. The grounded theory method was used to identify the age discrimination experienced by the elderly in their daily lives and to explore the consequences of such discrimination through self-ageism. According to the analysis results, the elderly respond not only to explicit discrimination but also to implicit discrimination. In this process, the stronger the pain of old age (poverty, disease, ignorance, and solitude) and the stronger the memory of failing to respond to discrimination, the higher the level of self-ageism. "Self-ageism" has internalized the negative image of the elderly, who have been discriminated against by age, resulting in disadvantages in terms of quality of life through various reject/separate/suspension actions in reality. In the presence of supportive resources such as health, institutional support, and caregivers, the elderly have room to overcome self-ageism through more active ways. However elderly people who cannot motivate themselves and they lack these resources, elderly are trapped in negative reflux caused by self-ageism and sustained a depressed and shrinking life. In this state, it is not easy to motivate themselves and make physical, cognitive, emotional and social responses. Therefore, in this analysis, we specifically noted two aspects, contextual conditions and interventional conditions, and proposed programs for synchronizing senior citizens and improving resiliency from a microscopic point of view, and argued for the need to develop systems such as supplementing welfare and health service systems related to the entire life cycle, expanding accessibility and 'age-integration' through 'Community Care', awareness improvement and anti-discrimination laws.

Carrageenan-Based Liquid Bioadhesives for Paper and Their Physical Properties (카라기난 기반 액상형 바이오 종이 접착제의 제조 및 물성에 관한 연구)

  • Oh, Seung-Jun;Han, Won-Sik;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.36 no.6
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    • pp.541-548
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    • 2020
  • There is a growing demand for natural materials to replace adhesives based on volatile organic compounds (VOCs). However, the exclusion of VOCs from the manufacturing process leads to difficulties in manufacturing, and reduction in productivity and preservability. In this paper, we report the manufacture of natural bioadhesives using the carrageenan component of seaweed. λ-carrageenan, isolated from the extracted total carrageenan, was used to prepare a highly stable adhesive for paper. The resulting composition was 52.0 ± 1.0% λ-carrageenan, 30.5 ± 0.5% Polyvinylpyrrolidone, 1.0 ± 0.05% ethylhexylglycerin, 1.5 ± 0.05% glycerin, 13.5 ± 0.5% dextrine, and 0.6 ± 0.05% food-grade antifoam emulsion. The viscosity was found to be 1.13 ± 0.07 × 105 cP (25℃), UV degradation occurred at pH6.22, drying rate was 15min, △b* was -10.79, and △E* ab was 8.18. The bioadhesive showed an excellent adhesion strength of 44.63 kgf/cm2. Thus this adhesive showed excellent fungal resistance and good adhesive persistence, without the presence of total volatile organic compounds (TVOC), formaldehyde (HCHO), and heavy metals.