• Safety and Health at Work
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• 제8권4호
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• pp.393-397
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• 2017

Background: It has been suggested that engaging technology can empower individuals to be more proactive about their health and reduce their health risks. The aim of the present intervention was to study the effects of technology-aided testing and feedback on physical activity and biological age of employees in a middle-sized enterprise. Methods: In all, 121 employees (mean age $42{\pm}10$ years) participated in the 12-month three-arm cluster randomized trial. The fitness measurement process (Body Age) determined the participants' biological age in years. Physical activity was measured with the International Physical Activity Questionnaire Short Form. Results: Physical activity did not change during the intervention. Biological age (better fitness) improved in all groups statistically significantly (p < 0.001), but with no interaction effects. The mean changes (years) in the groups were -2.20 for the controls, e2.83 for the group receiving their biological age and feedback, and -2.31 for the group receiving their biological age, feedback, and a training computer. Conclusion: Technology-aided testing with feedback does not seem to change the amount of physical activity but may enhance physical fitness measured by biological age.

• Biomolecules & Therapeutics
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• 제2권4호
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• pp.316-321
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• 1994

This study was undertaken to estimate whether nalbuphine, a mixed agonist/antagonist opioid analgesic produced psychic dependence. Moreover, the physical dependence liability of nalbuphine was compared with that of morphine after 7 days administrations of the drugs in mice and rats, and the effects of ginseng total saponin (GTS) on the development of physical dependence on nalbuphine were also studied. Nalbuphine did not produce psychic dependence. However, various abstinence signs precipitated by naloxone were observed in nalbuphine-dependent mice and rats. As the nature of the dependence syndrome produced by nalbuphine 30 mg/kg under these conditions seems similar to that induced by morphine 10 mg/kg, it is clear that nalbuphine possesses the substantial abuse potential. Therefore, nalbuphine may be needed to initiate more stringent controls for the prevention of nalbuphine abuse. On the other hand, GTS inhibited the development of physical dependence on nalbuphine and reduced the contents of dopamine and its metabolite in the brains of mice. Accordingly, results of this study suggest that the inhibitory effects of GTS on the development of physical dependence on nalbuphine may involve dopaminergic mechanism. GTS may be useful for the therapy of physical dependence on nalbuphine.

• 대한의생명과학회지
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• 제12권4호
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• pp.443-450
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• 2006

To demonstrate their possibilities as an enhanced vaccine delivery system, protein-loaded Poly lactide glycolide copolymer (PLGA) microspheres were prepared with different physical characteristics. Ethyl acetate (EA) solvent extraction process was employed to prepare microspheres and the effects of process parameters on drug release properties were evaluated. The biodeuadability of microspheres was also evaluated by the pH change and GPC (Gel permeation chromatography). Primary IgG antibody responses in BALB/c mice were compared with protein saline solutions as negative controls and adsorbed alum suspensions as positive controls after single subcutaneous injection for in vivo studies. The microspheres showed a erosion with a highly porous structure and did not keep their spherical shape at 45 days and this result could be confirmed by GPC. In vitro release of proteinous drug showed initial burst effect in all batches of microspheres, followed by gradual release over the next 4 weeks. PLGA microspheres were degraded until 45 days and the secondary structure of OVA was not affected by the preparation method. Enzyme-linked immunosorbent assays demonstrated that the single subcutaneous administrations of OVA-loaded PLGA microspheres induced enhanced serum IgG antibody response in comparison to negative and positive controls. These results demonstrated that microspheres providing the controlled release of antigens might be useful in advanced vaccine formulations for the parenteral carrier system.

• 대한후두음성언어의학회지
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• 제16권2호
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• pp.146-151
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• 2005

Objectives: Prospective study of quality of life in patients underwent microlaryngeal surgery for dysphonia was performed. Materials and Methods : 51 patients with dysphonia took part in the study, and patients with malignancies or functional voice disorder were excluded. Patients were asked to complete the SF-36 questionnaire before surgery and within 6-12 months after surgery. Preoperative and postoperative SF-36 scores were compared with data on 46 age-matched healthy controls. Results The most of SF-36 subscale scores showed significantly improvement after surgery, except of PF (physical functioning) and MH (mental health). Preoperative scores had significantly poorer than the normal controls on 6 subscales, but there is no statistically significant differences between postoperative scores and normal controls on 5 subscales. Conclusion In the study, patients with organic voice disorder show improvement in quality of life after microlaryngeal surgery.

• The Journal of Korean Physical Therapy
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• 제10권2호
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• pp.195-200
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• 1998

도인술은 경락과 경혈에 자극에 의한 체조법과 호흡법을 결합하여 기혈의 순환을 활발하게 하고 사기의 배설을 촉진시키므로 근육, 건, 인대의 탄력성과 활력성을 증강하고 관절의 활액 분비와 관절 주위의 순환을 촉진하고 경락을 통해 전신을 조정해 준다.(신준식, 1995). 내$\cdot$외관적 질환, 부인과 질환을 예방하고 치료하는 운동요법 중에 요통과 견괄절 질환에 대해서만 몇 가지 행법만 소개하므로 모든 질병을 치료보다 예방적인 측면으로 건강증진, 치료목적, 근 이완, 피로 회복의 효과를 달성할 수 있다. 도인법은 확고하게 과학적으로 증명된 것은 아니지만 질병 치료와 건강 증진 목적으로 현재까지 시행하고 있으므로 한방 물리치료의 한 분야이므로 좀 더 효과적이고 발전에 많은 활용하기 위하여 제한하는 바이다.

• 대한물리의학회지
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• 제14권1호
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• pp.15-23
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• 2019

PURPOSE: This study was conducted to investigate the effects of the myofascial meridians release technique on pain and postural control of college students with forward head posture and to compare the intervention effects of the Grastone massage and the Rollfing massage. METHODS: Thirty subjects with forward head posture were randomly and equally allocated to experimental group I (myofascial meridians release technique using Grastone massage, n=15) or experimental group II (myofascial meridians release using Rollfing massage, n=15). All subjects underwent 30 minutes of different myofascial meridians release techniques in addition to general physical therapy (hot pack: 15 min, interferential current therapy: 15 min, ultra sound: 5 min) three times a week for a total of 6 weeks. Outcome was measured before and after 4 weeks of intervention. RESULTS: In both groups, the numerical rating scale of pain was significantly decreased after intervention, with experimental group I showing a greater decrease than experimental group II. The neck disability index decreased significantly after intervention in both groups, with experimental group I showing a significantly greater decrease than the controls. The distance of the head forward displacement did not differ significantly between the two groups (p>.05). CONCLUSION: This study suggests that the Grastone method combined with the myofascial meridians release technique is a more effective intervention for improvement of pain and postural control in adults with moderate forward head posture.

• The Journal of Korean Physical Therapy
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• 제16권2호
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• pp.33-43
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• 2004

The multiple acupuncture techniques have been used to relieve the pain of lateral ankle sprain. Recently, early functional rehabilitation is emphasized in rehabilitative concepts using active ROM, facilitated proprioception, alphabet exercise and so forth. Similarly, in oriental rehabilition medicine, traditional movement technique called 'Dong-Ki' has been used to relieve pain of ankle sprain. So we used 'Dong-Ki' technique with SSP(silver spike point) electrotherapy transformed from alphabet exercise and evaluated the effects in method of randomized controlled trials. 27 outpatients with lateral ankle sprains were randomized into two groups : 15 samples and 12 controls. Sample group was treated with 'Dong-Ki' technique(writing his name with foot) with SSP electrotherapy to relieve pain during additionally. 'Dong-Ki'. Outcomes were measured by 10cm VAS and ankle circumference(cm). In terms of VAS, Sample group had inclination of pain relieving but not significantly meaningful. In terms of ankle circumference measurement, Sample group showed significantly improved.

• 한국전문물리치료학회지
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• 제5권3호
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• pp.48-55
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• 1998

The purpose of this study was to identify vital capacity (VC) in relation to the changing position of 19 patients with spinal cord injury (SCI) and 20 normal controls. Among the 19 SCI patients, there were 9 quadriplegics and 10 paraplegics. The vital capacity was measured in each subject during sitting, standing, lying, and head down position of 30 degrees. The data were analysed by the Kruskal-Wallis test, Mann-Whitney test, and Wilcoxon signed rank test. For the SCI, significant difference of VC accoring to the 4 positions between quadriplegics and paraplegics. In the control group, significant difference of VC according to the 4 positions. In 4 positions the VC of men were significantly larger than that of women between two groups. No statistical significant difference was shown in VC by the postural change between quadriplegics and paraplegics.

• 한국전문물리치료학회지
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• 제1권1호
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• pp.25-34
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• 1994

This study investigated the hypothesis that purposeful activity is an intrinsic motivator. Affecting exertion during the performance of purposeful and nonpurposeful activity was studied in 30 elementary school students. The subjects acted as their own controls in the performance of other exercise. The three experimental exercises were jumping rope, defined as a nonpurposeful activity, and jumping rope with reinforcement, defined as purposeful activity I, and jumping rope with double reinforcement (food), defined as purposeful activity II. Duration and cessation of exercise were entirely controlled by the subject. The number of jumps were measured immediately after cessation of exercise and duration of exercise in seconds by observer. The results were as follows : 1. There was a significant difference in the required time of performance between purposeful and nonpurposeful jumping (p< .05). 2. There was a significant difference in the number of jumps between nonpurposeful and nonpurposeful jumping after reinforcement. (p< .05). Implications for practice and further research are discussed.

• 진공이야기
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• 제1권3호
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• pp.21-27
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• 2014

Advanced process and integration for future semiconductor devices is approaching the physical limit. The new materials with low dimensional structure have recently attracted great attention due to its expandability for the future electronic devices. In order to apply the materials to future semiconductor devices, the control of carrier scattering is critical issue. That is, the carrier scattering with physical quantity in low dimensional structure significantly modulates the device characteristics. We introduce the role of defect in several future semiconductor materials and devices. The analysis of defect in the structure becomes the most important techniques. In particular, surface defect in nano structures totally controls the device characteristics. The changes imply that the metrology field is leading the future industry for semiconductor.