• 한국주거학회논문집
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• 제26권2호
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• pp.39-46
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• 2015

The 'pathways' in the Deteriorated Residential Area is the valuable place which represents the history of the community. The 'pathways' is the physical boundary which connects individual environment of private residential area to public environment and which has value as a medium for the definite site for regeneration of Deteriorated Residential Area. Thus, the 'pathways' is considered as the perfect material for the public design for spatial culture to regenerate the Deteriorated Residential Area. However, the most of the public design projects utilize the 'pathways' fragmentarily, there are few systematic studies based on the attribute of the Deteriorated Residential Area. The purpose of this study is the consideration on the attributes of the 'pathways', the detection of the spatial characteristics to find application of the 'pathways', and the cultivation of the baseline data for further research for the spatial nature of the Deteriorated Residential Area. For this study, theoretical consideration is practiced in advance to analyze the meaning of the 'pathways' and Deteriorated Residential Area, the case research is performed using design elements as the analytic frame, and the approach is inferred for systematic public design based on the above result. The objects of case research were chosen among the latest projects implemented in the Deteriorated Residential Area whose subject was 'pathways' and which showed successful result. The characteristics of them were investigated and the details were examined through the homepages of the projects, the reports related to the projects, research material, and interview with the people involved. And to conclude, 'pathways' represents the composition of contents, the space of movement, the formation of community, the landscape design, and the participatory design in the Deteriorated Residential Area. The 'pathways' also finds the proper secondary cultural material for the spatial characteristics and can create the space for the various movements, stay, and communication using the characteristics of movements. The narrow and closed space should be utilized actively to be altered into beautiful space and the Deteriorated Residential Area should be regenerated into coexistent design where people share their lives through sharing spaces.

• 에너지공학
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• 제11권2호
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• pp.136-141
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• 2002

석탄가스화 복합발전용 고온건식 탈황제의 반응성을 개선하기 위하여 $Al_2$O$_3$를 지지체로사용한 ZnO/Al$_2$O$_3$ 탈황제를 제조하고 반응특성을 조사하였다. ZnO/Al$_2$O$_3$의 성분함량 및 소성온도에 따른 물리화학적 구조변화를 XRD로 관찰하였고 ZnO의 소결 및 열화로 인한 활성저하를 $Al_2$O$_3$의 함량과 소성온도를 변화시켜 개선할 수 있음을 탈황 및 재생반응실험을 통하여 확인하였다. 마지막으로 첨가제를 함유한 ZnO/Al$_2$O$_3$ 탈황제의 내구성실험에 의한 고온건식 탈황제로의 사용가능성을 실험적으로 확인하였다.

• Archives of Plastic Surgery
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• 제37권3호
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• pp.207-212
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• 2010

Purpose: The object of this study is to develop a novel BMP-2 delivery system for continuous osteogenic differentiation and to induce osteogenesis of stem cells using a bi-phase alginate carrier in vitro. Methods: Alginate nanoparticle loaded BMP-2 was prepared by the reverse emulsification-diffusion technique. Physical properties and release profiles of alginate carriers were measured by Instron and ELISA kit, respectively. Cell viability and alkaline phosphate activity of hBMSCs differentiation was also evaluated by MTS and Metra BAP assays, respectively. Results: Optimal concentration for bi-phase alginate carrier was determined as 2 wt% by evaluating mechanical and biological properties, and differentiation of BMSCs for bone regeneration. The 2% bi-phase alginate carrier had the lowest initial and final release ratio. In addition, the 2% bi-phase alginate carrier had a little higher ALP activity than the homogeneous carrier. An improved controlled release profile was obtained by combining alginate hydrogel with lyophilized particles. Conclusion: Bi-phase alginate carrier has many advantages such as biocompatibility and controlled release capability. It is expected to be effective as a scaffold and carrier in bone tissue engineering.

• 농촌계획
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• 제20권1호
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• pp.105-113
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• 2014

This study analyzed settlement motivation, life satisfaction factors, policy requirement targeting return farmers on mountain village. 8 target villages where return farmers live at least 10 people were selected according as cooperation of the local governments through literature by considering the area of the whole country. The return farmers in target villages were conducted a face to face survey with village headman's pre-coordination from February to September 2013. A total of 94 surveys were performed and 87 copies were used in the analysis. According to the results, the most important factor influenced the decision to be a return farmer was "my family health(3.97)". The correlation analysis was performed to examine factors related with satisfaction of "return farmer life in general". The result showed that "change of physical health" was the most important correlativity with 0.544 correlation coefficient and 0.05 significant level and "family relationship" was followed with 0.424 correlation coefficient and 0.05 significant level. According to the "important factor for the successful return-farmer life", 42.7% of respondents chose "harmonious relationships with local residents" and "stable source of income" was chosen by 29.3% of residents. A questionnaire for the analysis of policy requirements showed that "education system related Forestry(Agriculture)" was the highest demand with 4.oo points. The result can be used as a basis for establishing policies with activation of mountain villages to attract to constantly increasing population of return farmers.

• 한국실내디자인학회논문집
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• 제24권6호
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• pp.192-201
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• 2015

This research aims to find planning issues on reuse of an industrial heritage as a cultural cluster and to suggest planning factors which can be referred when designing the similar cases. Analysis standards were formed through reviewing of precedent literatures, and the selected cases(i.e Shanghai M50, Yokohama BankART1929, and Incheon ArtPlatform) were analyzed to identify both physical and nonphysical planning characteristics. By combining analyses, the following results were obtained; (1) The demand and supply of the arts coexist in one place, and the studios and galleries are designed with high ceilings; (2) The regional and historical characteristics are revealed from preserving major architectural elements of previous buildings, and open spaces are provided to promote a variety of activities for local residents; (3) Various strategies to overcome disadvantage in location are developed, and the concepts of design can be easily recognized by buildings' exterior as the reused industrial heritage and the cultural cluster; (4) Diverse supports for artists make it possible to gather many competent artists, and the cooperative networks among artists play a pivotal role in the development of cultural cluster; (5) The cluster runs educational programs reflecting the needs of local residents, and builds a strong relationship with the local community by supporting regional art industry or developing linked programs; (6) The cluster serves various functions such as cafes, pubs, restaurants, art shops, and bookstores, and hosts appealing events and festivals to attract many people even who are not interested in arts.

• The Korean Journal of Physiology and Pharmacology
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• 제15권1호
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• pp.23-29
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• 2011

Melatonin, which is the main product of the pineal gland, has well documented antioxidant and immune-modulatory effects. Macrophages produce molecules that are known to play roles in inflammatory responses. We conducted microarray analysis to evaluate the global gene expression profiles in response to treatment with melatonin in lipopolysaccharide (LPS) activated RAW 264.7 macrophage cells. In addition, eight genes were subjected to real-time reverse transcription polymerase chain reaction (RT-PCR) to confirm the results of the microarray. The cells were treated with LPS or melatonin plus LPS for 24 hr. LPS induced the up-regulation of 1073 genes and the down-regulation of 1144 genes when compared to the control group. Melatonin pretreatment of LPS-stimulated RAW 264.7 cells resulted in the down regulation of 241 genes and up regulation of 164 genes. Interestingly, among genes related to macrophage-mediated immunity, LPS increased the expression of seven genes (Adora2b, Fcgr2b, Cish, Cxcl10, Clec4n, Il1a, and Il1b) and decreased the expression of one gene (Clec4a3). These changes in expression were attenuated by melatonin. Furthermore, the results of real-time PCR were similar to those of the microarray. Taken together, these results suggest that melatonin may have a suppressive effect on LPS-induced expression of genes involved in the regulation of immunity and defense in RAW 264.7 macrophage cells. Moreover, these results may explain beneficial effects of melatonin in the treatment of various inflammatory conditions.

• 한국결정성장학회지
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• 제25권3호
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• pp.98-104
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• 2015

Titanium barrier membranes are prepared to investigate the effect of surface-treatments, such as machining, electropolishing, anodizing, and electropolishing + TiN coating, on the biocompatibility and physical properties of the membranes. The surface roughness (Ra) of the membrane decreases from machining ($0.37{\pm}0.09{\mu}m$), TiN coating ($0.22{\pm}0.09{\mu}m$), electropolishing ($0.20{\pm}0.03{\mu}m$), to anodizing ($0.15{\pm}0.03{\mu}m$). The highest ductility (24.50 %) is observed for the electropolished Ti membrane. No evidence of causing cell lysis or toxicity is found for the membranes regardless of the surface-treatments. Cell adhesion results of L-929 and MG-63 show that the machined Ti membrane exhibits the highest cell adhesion while the electropolished membrane is the best membrane for the L-929 cell proliferation after 7 days. However, no appreciable difference in MG-63 cell proliferation among variously surface-treated membranes is detected, suggesting that the electropolished Ti membrane is likely to be the best membrane due to the synergic combination of tailored flexibility and excellent fibroblast proliferation.

• Journal of Periodontal and Implant Science
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• 제37권1호
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• pp.53-64
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• 2007

The aim of this study was to examine the possibility of periodontal ligament regeneration when autotransplantation was used by the periodontal ligament fibroblasts cultured on the acellular dermal matrix in teeth without a periodontal ligament. One minipig was used in this study. The mandibular and maxillary permanent incisors were ex-tracted for the culture of the periodontal ligament cells. The roots of the unextracted teeth were classified into a positive control group, in which the normal periodontal ligament was preserved. The roots of the extracted teeth were divided into the following two groups: The negative control group, in which the periodontal ligament had been removed and the acellular dermal matrix was not applied; and an experimental group, in which the periodontal ligament had been removed and periodontal ligament fibroblast cultured on an acellular dermal matrix was applied. The prepared teeth were transplanted, and completely submerged using physical barrier membranes. The animal was sacrificed 4 weeks after the autotransplant. The transplanted teeth were examined histologically. In this study, the periodontal ligament was normal in the positive control group, and ankylosis was discovered on the denuded root surface in the negative control group. Periodontal ligament-like connective tissue was found adjacent to the denuded root and the new cementum-like layer of hard tissue was formed in the experimental group. These results suggest that the periodontal ligament fibroblasts cultured on the acellular dermal matrix may play a role in regenerating the periodontal ligament-like tissue with new cememtum-like tissue formation.

• 공업화학
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• 제29권5호
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• pp.571-580
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• 2018

본 연구에서는 수용액에서 Pb(II)를 흡착 제거하기 위하여 커피찌꺼기(spent coffee grounds; SCG)와 점토광물인 견운모(sericite)를 혼합하여 복합흡착제(SS)를 제조하였다. FT-IR 분석결과 SS의 주요 관능기는 O-H, C=O와 C-N 그룹이었다. SS의 비표면적, 기공직경 그리고 양이온 치환 용량은 SCG와 sericite보다 크고, 높았다. SS 흡착제 제조를 위한 최적의 조건은 소성온도 $300^{\circ}C$, SCG : sericite 비율 8 : 2, 입자의 크기는 0.3 mm이었다. SS 흡착제를 이용하여 Pb(II)를 제거하기 위한 실험에서는 Langmuir 흡착식이 Freundlich보다 적합하였으며, Langmuir 등온흡착식에 의한 Pb(II)의 최대 흡착용량은 44.42 mg/g이었다. 또한, 열역학 분석에 의하면 SS 흡착제를 이용한 Pb(II)의 흡착 공정은 물리적인 흡착이었으며, 자연적인 발열반응이었다. SS 흡착제의 흡착-탈착 실험에서는 88-92%를 회수할 수 있었으나, 탈착 횟수가 증가할수록 SS 흡착제의 활성사이트는 감소하였다. 위의 실험결과 SS 흡착제는 전처리 없이 저렴하고, 효율적으로 Pb(II)를 수용액에서 흡착 제거할 수 있다.

• 공업화학
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• 제19권4호
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• pp.445-451
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• 2008

마이크로파를 이용하여 휘발성유기화합물(VOCs; Volatile Organic Compounds)로 오염된 활성탄을 재생하기 위하여, 절연물질로서 활석(Talc)과 Ni-Zn ferrite를 각각 활성탄에 코팅하여 벤젠의 흡착 및 탈착 특성을 조사하였다. 절연물질이 코팅된 활성탄의 물리적 특성 및 표면상태는 질소가스 흡착장치와 주사전자현미경(SEM)을 이용하여 각각 확인하였다. 비표면적과 벤젠에 대한 흡착량은 비례관계를 보였고, 활성탄에 활석이나 Ni-Zn ferrite를 코팅하면 마이크로파에 의한 불꽃방전을 억제할 수 있었다. 활성탄에 절연물질을 코팅하기 위해 사용한 바인더는 PS (potassium silicate)가 벤젠에 대한 흡착성능이 가장 우수한 것으로 나타났다. 마이크로파 출력에 따른 탈착량은 출력에 비례하는 경향을 보였고, 연속되는 흡착과 탈착과정이 5회 반복되더라도 재현성이 충분히 나타났다. 결과적으로 VOCs로 오염된 폐활성탄의 재생방법으로서, PS를 바인더로 사용하여 활석이나 Ni-Zn ferrite를 활성탄에 코팅하여 마이크로파로 탈착시키면 효과적임을 알 수 있었다.