• 운동영양학회지
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• 제24권2호
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• pp.38-46
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• 2020

[Purpose] This study aimed to investigate the effects of leucine-enriched essential amino acid (LEAA) supplementation on muscle fatigue and the level of inflammatory cytokines in wheelchair basketball players after a basketball game and interval training. [Methods] Of the ten recruited wheelchair basketball players (aged 34.5±8.9 years; lean body mass of 34.3±10.0 kg) who had spinal cord injury (SCI) and had undergone amputation, nine participated in the final test. These nine athletes received LEAA supplements (3 times 4.0 g/day) or placebo treatment in a double-blind, randomized, crossover study. We measured variables related to muscular fatigue and inflammatory response before the intense exercise and 4 days after recovery. [Results] The significant effect of LEAA supplementation was inhibition of circulating IL-6 levels in the LEAA-treated group compared with the placebo group (P < .05). However, no changes were observed in the TNF-α and creatinine kinase levels. Moreover, analysis of variance analysis showed no significant difference in the relative values of muscle soreness. However, the effect size analysis with Cohen's d reported a significant improvement in the relative values of whole body and back muscle soreness. [Conclusion] Our results revealed that LEAA supplementation before and after intense exercise could help reduce muscle soreness and IL-6 levels in wheelchair basketball players.

• Journal of Ginseng Research
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• 제35권3호
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• pp.331-338
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• 2011

Red ginseng (RG, the extract of Panax ginseng Meyer) has various biological and psychological activities and may also alleviate fatigue-related disorders. The present study was undertaken to evaluate what kind of fatigue red ginseng alleviate. Animals were orally administered with 50, 100, 200, 400 mg/kg of RG for 7 days. Before experiments were performed. Physiological stress (swimming, rotarod, and wire test) are behavioral parameters used to represent physical fatigue. Restraint stress and electric field test to a certain degree, induce psychological fatigue in animals. Plasma concentration of lactate and corticosterone (CORT) were also measured after these behavioral assays. RG supplementation (100 mg/kg) increased movement duration and rearing frequency of restrainted mice in comparison with control. 100 and 200 mg/kg of RG increased swimming time in cold water ($8{\pm}4^{\circ}C$) while at 100 mg/kg, RG increased electric field crossing over frequencies. 50, 100 and 200 mg/kg RG prolonged running time on the rotarod and at 100 mg/kg, it increased balancing time on the wire. RG at those doses also reduced falling frequencies. RG supplementation decreased plasma CORT levels, which was increased by stress. Lactate levels were not significantly altered. These results suggest that RG supplementation can alleviate more the damages induced by psychological than physical fatigue.

• 한국전문물리치료학회지
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• 제8권3호
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• pp.11-26
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• 2001

In rehabilitation programs involving muscle re-education and endurance exercise, it is necessary to confirm when fatigue occurs. It is also necessary to quantify fatigue, to confirm whether the muscle has been exercised sufficiently. In general, as fatigue occurs, the force-generating ability of the muscle is reduced. If the median frequency (MDF) obtained from electromyogram (EMG) power spectrum is correlated highly with work, then the timing and degree of fatigue may be confirmed. This study examined the relationship between work and MDF obtained from the EMG power spectrum during repetitive isokinetic exercise. Surface EMG signals were collected from biceps brachii and vastus lateralis of 52 normal subjects (26 males, 26 females) at $120^{\circ}/sec$ and $60^{\circ}/sec$ while performing an isokinetic exercise. The exercise was finished at 25% of peak work. MDF data was obtained using a moving fast Fourier transformation (FFT), and random noise was removed using the inverse FFT, then a new MDF data was obtained from the main signal. There was a high correlation between work and MDF during repetitiv isokinetic exercise in the biceps brachii and vastus lateralis of males and the biceps brachii of females (r=.50~.77). However, there was a low correlation between work and MDF in the vastus lateralis of females (r=.06~.19).

• 한국전문물리치료학회지
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• 제21권3호
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• pp.28-37
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• 2014

The purpose of this study was to investigate the effects of smartphone use on muscle fatigue and tenderness in the cervical erector spinae (CES) and the upper trapezius (UT) and on the cervical range of motion among subjects with and without neck muscle pain. The subjects were 30 smartphone users in their 20 s who -were assigned to either an experimental group with neck muscle pain or a control group without neck muscle pain. Muscle fatigue and tenderness in the CES and the UT as well as the subjects' cervical range of motion were measured before and after 20-min smartphone sessions in a sitting position. In a between-group comparison of muscle fatigue, the experimental group showed a significantly greater decrease in median frequency in the CES and the right UT after smartphone use (p<.05). Regarding the assessment of muscle tenderness after smartphone use, the experimental group showed a statistically significant decrease in the pressure-pain threshold (PPT) in all muscles (p<.05), whereas the control group showed a significantly decreased PPT in the right CES and the UT (p<.05). The assessment of the cervical range of motion revealed a statistically significant reduction in the cervical flexion-extension and left lateral flexion in the experimental group (p<.05) after smartphone use. However, there was no significant change in the cervical range of motion in the control group (p>.05) after smartphone use. When compared with the control group, the experimental group demonstrated greater changes in cervical extension, lateral flexion, and rotation, except for cervical flexion (p<.05). In conclusion, when smartphone users have pre-existing neck muscle pain, the use of a smartphone further increased muscle fatigue and tenderness in the neck and reduced PPT and the cervical range of motion.

• 한국도로학회논문집
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• 제15권1호
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• pp.1-9
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• 2013

PURPOSES: The purpose of this study is to evaluate physical properties, durability, fatigue resistance, and long-term performance of poly-urethane concrete (PU) which can be possible application of thin layer on long-span orthotropic steel bridge and to check structural stability of bridge structure. METHODS : Various tests of physical properties, such as flexural strength, tensile strength, bond strength and coefficient of thermal expansion tests were conducted for physical property evaluation using two types of poly urethane concrete which have different curing time. Freezing and thawing test, accelerated weathering test and chloride ion penetration test were performed to evaluate the effect of exposed to marine environment. Beam fatigue test and small scale accelerated pavement test were performed to assess the resistance of PU against fatigue damage and long-term performance. Structural analysis were conducted to figure out structural stability of bridge structure and thin bridge deck pavement system. RESULTS: The property tests results showed that similar results were observed overall however the flexural strength of PUa was higher than those of PUb. It was also found that PU materials showed durability at marine environment. Beam fatigue test results showed that the resistances of the PUa against fatigue damage were two times higher than those of the PUb. It was found form small scale accelerated pavement test to evaluate long-term performance that there is no distress observed after 800,000 load applications. Structural analysis to figure out structural stability of bridge structure and thin bridge deck pavement system indicated that bridge structures were needed to increase thickness of steel deck plate or to improve longitudinal rib shape. CONCLUSIONS: It has been known that the use of PU can be positively considered to thin layer on long-span orthotropic steel bridge in terms of properties considered marine environment, resistance of fatigue damage and long-term performance.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.260-268
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• 2016

본 연구는 만성질환자 노인의 피로, 우울 및 신체활동의 정도와 그 관계를 밝히고, 우울 및 신체활동이 피로에 미치는 영향을 파악하기 위한 서술적 조사 연구이다. 연구 대상자는 경북지역의 3곳의 의료기관 외래를 방문한 500명의 만성질환 노인이었으며, 자료는 일반적 특성, 피로, 우울과 신체활동에 관한 설문지를 통해 수집되었다. 수집된 자료는 ANOVA, t-test, sheffe test, pearson's correlation coefficient와 hierarchial regression으로 분석하였다. 연구결과 만성질환자의 피로는 우울과는 음의 상관관계를, 신체활동 정도와는 양의 상관관계를 보였고, 일반적 특성과의 차이비교에서는 연령과 성별, 학력에서 차이가 있었다. 또한 피로와 차이를 보인 연령, 성별 및 학력을 통제하기 위해 위계적 회귀분석을 실시한 결과 1단계 모형에서 연령, 성별 및 학력은 피로에 6%의 영향력을 가지고 있었고, 2단계 모형에서는 우울과 신체활동은 만성질환 노인의 피로에 16%의 영향력을 갖는 것으로 나타났다. 결론적으로 만성질환자 노인의 피로는 우울 및 신체활동에 영향을 받으므로 우울의 중재와 신체활동 향상를 위한 노력은 피로를 감소시키는 데에 도움이 될 수 있다. 따라서 만성질환을 가진 노인에 대한 피로 중재에는 우울을 감소시키기 위한 방안과 신체활동을 증가시킬 수 있는 전략이 함께 포함되어야 할 것이다. 본 연구 결과는 만성질환 노인의 피로 정도를 감소시키기 위한 전략을 개발하는 데에 기초자료로 활용할 수 있다.

• 한국콘텐츠학회논문지
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• 제17권4호
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• pp.285-293
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• 2017

이 연구는 그 동안 조직 구성원들의 피로도와 피로도가 조직에 미치는 영향에 대한 연구들이 계속해서 진행되어 왔지만, Saito(1999)의 전체설문을 사용한 연구와 조직몰입의 하위변수를 종합적으로 살펴본 연구는 없었다는 인식에서 출발하여 경찰공무원의 피로도 수준을 측정하고 피로도가 조직몰입에 미치는 영향을 실증적으로 검증하였다. 선행연구의 검토를 통하여, 경찰공무원의 피로도(정신적 피로, 육체적 피로, 신체적 부조화)를 독립변수로, 조직몰입(감정몰입, 지속몰입, 규범몰입)을 종속변수로 선정하였다. 이 연구의 의미와 시사점은 다음과 같다. 첫째, 이론적 관점에서 보면, 이 연구는 경찰조직을 대상으로 Saito(1999)의 전체 척도를 사용하고, 조직몰입의 하위변수와의 관계를 종합적으로 검증한 최초의 연구로서 가치가 있다는 것이며, 조직 관리자에게 피로도 관리의 중요성을 다시 한 번 확인시켜 주었다는 점이다. 둘째, 더 나아가 조직관리 관점에서 보면, 경찰조직의 근간을 이루는 재직기간이 5-10년이며, 계급이 경장과 경사인 경찰공무원들의 피로도를 조직차원에서 측정하고 적극적으로 관리하려는 노력이 필요하다는 점과, 이들을 대상으로 그들이 가지고 있는 조직에 대한 태도를 개선시키기 위한 교육훈련 프로그램의 개발이 필요하다는 것을 시사한다.

• 동의생리병리학회지
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• 제34권1호
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• pp.37-44
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• 2020

Previous studies have reported an association between poor sleep and various symptoms and diseases, such as fatigue, obesity, depression, and anxiety. The effects of poor sleep may differ by age and sex. In addition, sleep characteristics and their effects may vary according to Sasang constitutional type. The aim of this study was to investigate the associations between sleep quality, fatigue, and quality of life and to assess whether these differ by constitutional type. Participants were individuals aged 40-69 years living in two Korean communities in 2012-2014. Sleep quality, fatigue, and quality of life were measured using the Pittsburgh Sleep Quality Index (PSQI), the Fatigue Severity Scale, and the 12-item Short Form Health Survey, respectively. The effects of total PSQI score and PSQI component scores were analyzed using a generalized additive model. A Korean Sasang constitutional diagnostic questionnaire was used to assess Sasang constitution. Data for 5,793 participants were analyzed. Poor sleep quality was related to greater fatigue, and lower physical and mental quality of life. The PSQI components including subjective sleep quality, sleep latency, sleep disturbances, use of sleep medications, and daytime dysfunction were associated with fatigue and physical and mental quality of life. Sleep quality was significantly lower in So-Eum compared to So-Yang and Tae-Eum. PSQI component scores for fatigue and quality of life differed significantly by Sasang constitution: for Tae-Eum, sleep latency and use of sleep medications; for So-Eum, daytime dysfunction; and for So-Yang, use of sleep medications and daytime dysfunction. The effects of different aspects of sleep quality differ by Sasang constitution. To improve sleep quality, interventions need to be tailored to constitutional type.

• 셀메드
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• 제6권2호
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• pp.13.1-13.7
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• 2016

Fatigue is a common complaint and affects the quality of life in modern people. Physical stress may induce activation of certain immune cells. Fermented porcine placenta (FPP) has been used to alleviate fatigue. Inflammatory cytokines are produced by physical stress and results in symptoms of fatigue. However, the role of FPP on fatigue-associated inflammatory cytokine production has not been elucidated yet. Thus, we estimated the anti-fatigue effect of FPP and its active components, leucine (Leu) and lysine (Lys) in activated RAW264.7 macrophages and forced swimming test (FST) fatigue animal model. Pretreatment with FPP, Leu, or Lys significantly inhibited the lipopolysaccharide (LPS)-induced tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production without inducing cytotoxicity on LPS-stimulated RAW264.7 macrophages. FPP, Leu, or Lys inhibited the production of nitric oxide and downregulated the expression of inducible nitric oxide synthase on LPS-stimulated RAW264.7 macrophages. Furthermore, caspase-1 activities increased by LPS were significantly reduced by FPP, Leu, or Lys. In the FST, inflammatory cytokine levels of the mice administrated with FPP, Lys, and Leu were significantly reduced compared with the control group at 21 days. Collectively, these results show that anti-fatigue effect of FPP and its active components, Leu and Lys might be derived from the down-regulating of inflammatory mediators.

• 기본간호학회지
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• 제11권3호
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• pp.317-326
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• 2004

Purpose: This study was done to identify correlations between fatigue and quality of lift in clinical nurses. Method: A sample of 294 nurses working in 3 general hospitals answered a questionnaire containing Yoshitake's fatigue scale and WHOQOL-BREF. Data were analyzed using t-test, ANOVA and Pearson correlation coefficients. The SPSS/WIN 11.0 version program was used. Results: The score for level of fatigue was 2.11 (52.7%) and quality of lift, 2.89 (57.8%). The level of fatigue was highest in the physical domain followed by psychical and nervous-sensual domain in that order. There were statistically significant differences in scores of fatigue depending on the nurse's age, marital status, career, position, health status and present illness. Quality of life had the highest score in the social domain followed by physical, overall, psychological, and environmental domain in that order. There were statistically significant differences in scores on quality of life depending on nurse's age, marital status, career, position, health status and present illness. Conclusion: The relationship between fatigue and quality of lift revealed a significant negative correlation. Based on this study, nursing administrators need to reduce the level of nurse fatigue by providing various programs, which improve quality of life.