• International Journal of Computer Science & Network Security
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• 제21권5호
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• pp.52-56
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• 2021

There is no assurance that malware could only cause virtual damage to computer programs and data as its potential is endless. However, legal provisions were earlier developed to cater to either a physical damage caused by a physical action or a virtual damage caused by a virtual action. When crossovers occur, it becomes quite uncertain as to how viable the current laws are in handling this matter. The author seeks to address the issue from the perspective of the laws of Malaysia.

• Molecules and Cells
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• 제27권5호
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• pp.557-562
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• 2009

We examined the effects of the NADPH oxidase p22phox C242T polymorphism on endurance exercise performance and oxidative DNA damage in response to acute and chronic exercises. One hundred three subjects were recruited, among which 26 healthy subjects (CC: 12, TC: 12, and TT: 2) were studied during rest, exercise at 85% $VO_2max$, and recovery before and after 8 weeks of treadmill running. Lymphocyte DNA damage increased significantly in response to exercise (p < 0.05). There were no significant differences in plasma MDA, SOD concentrations and lymphocyte DNA damage between CC genotype and T allele group, but significant endurance training differences were observed. Endurance training increased exercise time to exhaustion in both the CC genotype and T allele groups (p < 0.05) but no significant difference was found between groups. The results of the current study with young, healthy, Korean men are interpreted to mean that 1) the majority had the CC genotype of the NADPH oxidase p22phox C242T polymorphism (82.5%: CC, 15.5%: TC, 1.9%: TT), 2) acute exercise increased lymphocyte DNA damage, 3) endurance training significantly increased exercise time to exhaustion, and alleviated lymphocyte DNA damage, and 4) The NADPH oxidase p22phox C242T polymorphism, however, did not alter lymphocyte DNA damage or exercise performance at rest, immediately after exercise, or during recovery.

• The Journal of Korean Physical Therapy
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• 제13권2호
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• pp.407-420
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• 2001

This article provide information pertaining to recent scientific findings regarding neural and motor control development and the effects of brain damage on that development. Clinical and scientific issues pertaining to perinatal and adult-onset brain damage are discussed. The article is intended to provide the clinician with new information that will assist in patient assessment and the establishment of therapeutic interventions

• 한국응용과학기술학회지
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• 제35권3호
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• pp.778-786
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• 2018

We investigated the effect of different exercise intensities on biomarkers of oxidant-antioxidant balance, inflammation, and muscle damage. Eighteen healthy and untrained male subjects were enrolled.Subjects were randomly and equally assigned to a moderate-intensityexercise(MIE, $65%VO_2max$) group(n=9) or a high-intensity exercise(HIE, $85%VO_2max$) group(n=9).Blood samples were collectedimmediately pre-exercise, post-exercise, and 60min post-exercisetoexamine oxidant-antioxidant balance(d-ROMs; BAP), inflammation(CRP; fibrinogen), muscle damage(CK; LDH), and lactate. Serum d-ROMs and BAP levels were significantly increased post-exercise compared with pre-exercise levels in HIE group(p<0.05). Lactate levels were significantly increased post-exercise compared pre-exercise levels in both the MIE and HIE groups(p<0.05). In addition, post-exercise serum d-ROMs and plasma lactate levels were significantly higher in the HIE group than in the MIE group(p<0.05). These results suggest that although relatively high-intensity exercises may increase oxidative stress levels in the body, they do not produce inflammatory response and/or muscle damage.

• The Journal of Korean Physical Therapy
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• 제10권1호
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• pp.23-30
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• 1998

The purpose of this study was to analyze the delayed muscle soreness after exercise and the indicators of muscle damage. Subjects of this study were 9 male students. Some muscle enzymes and others(GOT, LDH, ALD, CPK in serum, WBC, ESR) that known as the indicators of muscle damage were measured before exercise. After measurements they run on a treadmill ($incline:25\%$, speed;3.5miles/h) for 7 min. on an average. The intensity of this kind of exercise was $90.5\%$ of maximal exercise intensity. After exercise, same indicators were measured at the just after exercise, 24hr after, 48hr after, 72hr after. Also muscle soreness level was evaluated at same intervals by make use of Modified Abraham's scale. The result was as follow: There was no relationships between muscle soreness and the indicators of muscle damage but ALD was the most important indicator that can be explains the muscle soreness very well.

• Journal of Pharmaceutical Investigation
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• 제39권2호
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• pp.107-110
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• 2009

To investigate the interaction and skin damage of valsartan with polysorbate 80, the physical mixture of valsartan and polysorbate 80 was prepared and then its adhesion, dispersibility, DSC and skin damage in nude rats were investigated. The physical mixture of valsartan and polysorbate 80 appeared as an aggregated form and could hardly be dispersed in water. The DSC curve showed that physical mixture disappeared the intrinsic peaks of valsartan and polysorbate 80 at about $115^{\circ}C$ and $170^{\circ}C$, respectively. It appeared a new relatively broad endothermic peak at about $150^{\circ}C$, suggesting that valsartan was chemically interacted with polysorbate 80. Furthermore, it induced the severe skin irritation and damage in nude mice. Thus, polysorbate 80 must not be used in the preparation of valsartan-loaded pharmaceutical dosage forms.

• 대한통합의학회지
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• 제8권1호
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• pp.15-25
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• 2020

Purpose : Sexual harassment cases involving health and medical workers, including physical therapists, nurses and psychotherapists, are on the rise. Despite the increased incidence of sexual harassment, prior studies show that physical therapists, nursing assistants and caregivers are not doing well cope with sexual harassment. Therefore this study examines the factors associated with sexual harassment damage experience among physical therapists, as well as the relationship between sexual harassment damage experience and job-related aspects. It is intended to prepare basic data for programs and research that can mediate these issues. Methods : We conducted a self-reported questionnaire survey of 200 physical therapists working at medical institutions in the Seoul metropolitan area. The survey items included sexual harassment experience and job-related aspects such as satisfaction, stress, burnout, and engagement. A correlation analysis was conducted to clarify the relationship between sexual harassment experience and job-related factors, and multiple regression analysis was conducted to verify the correlations of sexual harassment experience on physical therapists' job. Results : There was a weak correlation between sexual harassment experience, job satisfaction, and job engagement, and a moderate correlation between sexual harassment experience, job stress, and job burnout. The impact of sexual harassment experience on job had a significant correlation on job satisfaction, job stress and burnout. Conclusions : Sexual harassment damage experience among physical therapists had a significant impact on many job aspects. Thus, there is a need for countermeasures and education to prevent sexual harassment, or at least effectively cope with the consequences. It is proposed to expand to other local or national units as follow-up studies, to study other factors affecting sexual harassment damage experience, and to develop and verify programs to cope with or prevent sexual harassment damage experience.

• The Journal of Korean Physical Therapy
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• 제17권2호
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• pp.67-87
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• 2005

Impaired sensorimotor function of the hand ipsilateral to a unilateral brain damage has been reported in a variety of motor task. however, it is still the controversial issue because of the difficulty of detection in clinical situation, patients' variability(time after onset, contralateral upper extremity severity, other cognitive functions including apraxia), and the performed various motor task. The purpose of this study is to determine the presence of ipsilateral motor deficit following unilateral brain damage in three different specific tasks(hand tapping, visual tracking and coin rotation) compared with healthy age-sex matched control group using the same hand and to investigate the lateralized motor control in each hemispheric function. Findings revealed that stroke patients with unilateral brain damage experienced difficulties with rapid-simple repetitive movement, visuomotor coordination, complex sequencing movement on ipsilateral side. Also, Comparison of the left-hemispheric stroke groups and the right-hemispheric stroke groups revealed that patients with a left-hemisphere damage tended to be more variable in performing all of the three tasks. These results show that stroke patient with left hemisphere damage has more ipsilateral motor deficit, and the left hemisphere contributes to the processing of motor control that necessary for the executing actions with ipsilateral hand.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.259-262
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• 2002

This paper provides the experimental verification of a non-destructive time domain approach to examine structural damage. Time histories of the vibration response of structure were used to identify the presence of damage. Damage in a structure cause changes in the physical coefficients of mass density, elastic modulus and damping coefficient. This paper examines the use of beam like structures with PVDF sensor and PZT actuator to perform identification of those physical parameters, and hence to detect the damage. Experimental results are presented from tests on cantilevered composite beams damaged at different location and with damage of different dimensions. It is demonstrated that the method can sense the presence of damage, and characterize the damage to a satisfactory precision.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2013년도 춘계학술대회 논문집
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• pp.179-180
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• 2013